David Leitsch

Medical University of Vienna

H指数:26

被引数:2,407

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The NfsB-like nitroreductase RdxA in Helicobacter pylori is a flavin reductase: possible implications for metronidazole resistance

幽门螺杆菌中NfsB样硝基还原酶RdxA是一种黄素还原酶：对甲硝唑耐药性的可能影响

Biochimie

IF3

2026-09-280

OAAI

Downregulation of an NfsA-like nitroreductase causes metronidazole resistance in Gardnerella vaginalis

NfsA样硝基还原酶的下调会导致加德纳菌对甲硝唑产生耐药性。

International Journal of Antimicrobial Agents

IF4.6

2025-12-010

OAAI

Culturing of Giardia lamblia under microaerobic conditions can impact metronidazole susceptibility by inducing increased expression of antioxidant enzymes

在微需氧条件下培养贾第鞭毛虫（Giardia lamblia）可通过诱导抗氧化酶表达增加来影响甲硝唑敏感性。

international journal for parasitology drugs and drug resistance

IF0

2025-02-010

OAAI

Comparative proteomic analysis of metronidazole-sensitive and resistant Trichomonas vaginalis suggests a novel mode of metronidazole action and resistance

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2024-12-012

OAAI

Evaluating the amoeba thioredoxin reductase selenoprotein as potential drug target for treatment of Acanthamoeba infections

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2024-12-010

OAAI

Proteomics-Based RT-qPCR and Functional Analysis of 18 Genes in Metronidazole Resistance of Bacteroides fragilis

ANTIBIOTICS-BASEL

IF4.6

2024-02-220

A Comparison of Bottom-Up Proteomic Sample Preparation Methods for the Human Parasite Trichomonas vaginalis

ACS OMEGA

IF4.3

2024-02-136

OAAI

Proteomic analysis of metronidazole resistance in the human facultative pathogen Bacteroides fragilis

人类兼性病原体脆弱拟杆菌对甲硝唑耐药性的蛋白质组学分析

FRONTIERS IN MICROBIOLOGY

IF4.5

2023-03-314

OAAI

Modulation of Iron Import and Metronidazole Resistance in Bacteroides fragilis Harboring a nimA Gene

FRONTIERS IN MICROBIOLOGY

IF4.5

2022-06-0912

OAAI

Haemin deprivation renders Bacteroides fragilis hypersusceptible to metronidazole and cancels high-level metronidazole resistance

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2022-01-198

OAAI

A reassessment of the role of oxygen scavenging enzymes in the emergence of metronidazole resistance in trichomonads

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2021-08-015

OAAI

An unusual thioredoxin system in the facultative parasite Acanthamoeba castellanii

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2021-02-1812

OAAI

Validation of reference genes for the normalization of RT-qPCR gene expression in Acanthamoeba spp.

SCIENTIFIC REPORTS

IF3.9

2020-06-2550

OAAI

A novel 5-Plex qPCR-HRM assay detecting human diarrheal parasites

GUT PATHOGENS

IF4

2020-05-2910

OAAI

Metabolomic Profiling of Wildtype and Transgenic Giardia lamblia Strains by 1H HR-MAS NMR Spectroscopy

METABOLITES

IF3.7

2020-01-307

OAAI

Activity of methylgerambullin from Glycosmis species (Rutaceae) against Entamoeba histolytica and Giardia duodenalis in vitro

来自糖基物种 (芸香科) 的甲基gerambullin对溶组织内阿米巴和十二指肠贾第鞭毛虫的体外活性

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2019-08-018

OAAI

Redox Pathways as Drug Targets in Microaerophilic Parasites

Trends in Parasitology

IF6.6

2018-07-0124

PREAI

Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2017-12-0125

OAAI

Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2016-12-0144

OAAI

Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2015-08-0144

OAAI

David Leitsch

个人简介

教育背景

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