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G

Glenn A. McConkey

University of Leeds

H指数:37

被引数:4,272

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Structure-guided targeting of Plasmodium falciparum aminopeptidase P: exploiting S4’ dimer-interface interactions for selective antimalarial drug design

基于结构的恶性疟原虫氨肽酶P靶向：利用S4'二聚体界面相互作用进行选择性抗疟药设计

Expert Opinion on Therapeutic Targets

IF4.4

2026-10-030

OA

Hydroxamate-based inhibitors reveal structural determinants of selectivity for Plasmodium falciparum aminopeptidase P

羟肟酸基抑制剂揭示恶性疟原虫氨肽酶P的选择性结构决定因素

Journal of Biological Chemistry

IF3.9

2026-04-010

OAAI

Toxoplasma gondii infection induces extracellular vesicle miRNAs in synaptic plasticity and neural mechanisms

弓形虫感染诱导突触可塑性和神经机制中的细胞外囊泡miRNAs

Extracellular Vesicles and Circulating Nucleic Acids

IF4.8

2026-03-010

PRE

The role of parasite-produced dopamine in Toxoplasma gondii-altered host behaviour

弓形虫（Toxoplasma gondii）改变宿主行为中寄生虫产生的多巴胺的作用

Nature Communications

IF15.7

2025-12-050

OAAI

Infection-induced extracellular vesicles evoke neuronal transcriptional and epigenetic changes

SCIENTIFIC REPORTS

IF3.9

2023-04-279

OAAI

Choosing drugs for UK COVID-19 treatment trials COMMENT

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2021-12-075

OA

Combination therapies for COVID-19: An overview of the clinical trials landscape

新型冠状病毒肺炎的联合治疗: 临床试验概况

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-10-1726

OAAI

Noradrenergic Signaling and Neuroinflammation Crosstalk Regulate Toxoplasma gondi-Induced Behavioral Changes

TRENDS IN IMMUNOLOGY

IF13.9

2020-12-0114

OAAI

Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection

IF3.3

2017-05-1757

OAAI

Pantothenic Acid Biosynthesis in the Parasite Toxoplasma gondii: a Target for Chemotherapy

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-11-0113

OAAI

Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-06-1550

PREAI

PlasmoPredict: a gene function prediction website for Plasmodium falciparum

Trends in Parasitology

IF6.6

2010-03-013

PREAI

The effect of Toxoplasma gondii on host behaviour: studies on mechanism of action using psychotropics, anti-parasite medication and parasite genes

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2009-09-011

PREAI

Alio intuitu: the automated reconstruction of the metabolic networks of parasites

Trends in Parasitology

IF6.6

2009-09-013

PREAI

Prediction of horizontal gene transfers in eukaryotes: approaches and challenges

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2009-07-2218

PREAI

The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes

IF9.4

2009-04-1555

OAAI

Structure-Based Design, Synthesis, and Characterization of Inhibitors of Human and Plasmodium falciparum Dihydroorotate Dehydrogenases

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-04-0789

PREAI

metaTIGER: a metabolic evolution resource

NUCLEIC ACIDS RESEARCH

IF13.1

2008-10-2527

OAAI

Metabolic reconstruction and analysis for parasite genomes

Trends in Parasitology

IF6.6

2007-11-0139

PREAI

Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-12-2973

PREAI