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Disease-Attenuated Pneumococcal Biosynthesis Gene Mutants Invade the Mucosal Epithelium and Induce Innate Immunity 致病性减弱的肺炎链球菌生物合成基因突变体侵袭黏膜上皮并诱导固有免疫 Weight, Caroline M.; Pollara, Gabriele; Betts, Modupeh; Ragazzini, Roberta; Ramos-Sevillano, Elisa; Reine, Jesus; Whelan, Matthew; Afonso Guerra-Assuncao, Jose; Connor, Michael; Bonfanti, Paola; Jolly, Clare; Noursadeghi, Mahdad; Ferreira, Daniela M.; Brown, Jeremy S.; Heyderman, Robert S. 分享 收藏
Leveraging paired serology to estimate the incidence of typhoidal Salmonella infection in the STRATAA study 利用配对血清学方法估算STRATAA研究中伤寒沙门氏菌感染的发病率 Walker, Jo; Russell, Paula; Kermack, Leanne; Van, Tan Trinh; Thieu Nga, Tran Vu; Mylona, Elli; Camara, Susana; Kim, Young Chan; Shrestha, Sonu; Gehlhaar, Arne; Scott, Josefin Bartholdson; Khanam, Farhana; Shakya, Mila; Thindwa, Deus; Gordon, Melita A.; Basnyat, Buddha; Clemens, John D.; Qadri, Firdausi; Heyderman, Robert S.; Dolecek, Christine; Tonks, Susan; Darton, Thomas C.; Pollard, Andrew J.; Baker, Stephen; Meiring, James E.; Voysey, Merryn; Pitzer, Virginia E.; STRATAA Study Grp 分享 收藏
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High Propensity for Multidrug-Resistant Pneumococcal Shedding Among Adults Living With HIV on Stable Antiretroviral Therapy in Malawi 马拉维接受稳定抗逆转录病毒治疗的HIV感染者中，肺炎链球菌多药耐药分离株高易感性。 Sibale, Lusako L.; Kalata, Newton; Mitole, Ndaona; Nyazika, Tinashe K.; Phiri, Joseph A.; Kusakala, Alice; Khwiya, Mercy; Sagawa, Gift; Lo, Stephanie W.; Chaguza, Chrispin; Thindwa, Deus; Swarthout, Todd D.; French, Neil; Malisita, Ken; Kamng'ona, Arox; Ferreira, Daniela M.; Bentley, Stephen D.; Heyderman, Robert S.; Kwambana-Adams, Brenda A.; Jambo, Kondwani C. 分享 收藏
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Evaluating methods for identifying and quantifying Streptococcus pneumoniae co-colonization using next-generation sequencing data Hackman, Jada; Hibberd, Martin L.; Swarthout, Todd D.; Hinds, Jason; Ashall, James; Sheppard, Carmen; Tonkin-Hill, Gerry; Gould, Kate; Brown, Comfort; Msefula, Jacquline; Mataya, Andrew A.; Toizumi, Michiko; Yoshida, Lay-Myint; French, Neil; Heyderman, Robert S.; Flasche, Stefan; Kwambana, Brenda; Hue, Stephane 分享 收藏
SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections Rosenheim, Joshua; Gupta, Rishi K.; Thakker, Clare; Mann, Tiffeney; Bell, Lucy C. K.; Broderick, Claire M.; Madon, Kieran; Papargyris, Loukas; Dayananda, Pete; Kwok, Andrew J.; Greenan-Barrett, James; Wagstaffe, Helen R.; Conibear, Emily; Fenn, Joe; Hakki, Seran; Lindeboom, Rik G. H.; Dratva, Lisa M.; Lemetais, Briac; Weight, Caroline M.; Venturini, Cristina; Kaforou, Myrsini; Levin, Michael; Kalinova, Mariya; Mann, Alex J.; Catchpole, Andrew; Knight, Julian C.; Nikolic, Marko Z.; Teichmann, Sarah A.; Killingley, Ben; Barclay, Wendy; Chain, Benjamin M.; Lalvani, Ajit; Heyderman, Robert S.; Chiu, Christopher; Noursadeghi, Mahdad 分享 收藏
Radiographically confirmed pneumonia in Malawian children and associated pneumococcal carriage after introduction of the 13-valent pneumococcal conjugate vaccine Mzumara, Grace; Chirombo, James; Swarthout, Todd D.; Bar-Zeev, Naor; Harawa, Philliness Prisca; Jalloh, Mohamed Sanusi; Kirolos, Amir; Mukhula, Victoria; Newberry, Laura; Ogunlade, Olawale; Wachepa, Richard; French, Neil; Heyderman, Robert S.; Tam, Pui-Ying Iroh 分享 收藏
Population genomics of Streptococcus mitis in UK and Ireland bloodstream infection and infective endocarditis cases Kalizang'oma, Akuzike; Richard, Damien; Kwambana-Adams, Brenda; Coelho, Juliana; Broughton, Karen; Pichon, Bruno; Hopkins, Katie L.; Chalker, Victoria; Beleza, Sandra; Bentley, Stephen D.; Chaguza, Chrispin; Heyderman, Robert S. 分享 收藏
Integration and validation of host transcript signatures, including a novel 3-transcript tuberculosis signature, to enable one-step multiclass diagnosis of childhood febrile disease 整合和验证宿主转录本签名，包括一个新的3转录本结核病签名，以实现儿童发热性疾病的一步多类诊断 Channon-Wells, Samuel; Habgood-Coote, Dominic; Vito, Ortensia; Galassini, Rachel; Wright, Victoria J.; Brent, Andrew J.; Heyderman, Robert S.; Anderson, Suzanne T.; Eley, Brian; Martinon-Torres, Federico; Levin, Michael; Kaforou, Myrsini; Herberg, Jethro A. 分享 收藏
Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of pneumococcal conjugate vaccine in Blantyre, Malawi Cave, Rory; Kalizang'oma, Akuzike; Chaguza, Chrispin; Mwalukomo, Thandie S.; Kamng'ona, Arox; Brown, Comfort; Msefula, Jacquline; Bonomali, Farouck; Nyirenda, Roseline; Swarthout, Todd D.; Kwambana-Adams, Brenda; French, Neil; Heyderman, Robert S. 分享 收藏
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Clonal Expansion of a Streptococcus pneumoniae Serotype 3 Capsule Variant Sequence Type 700 With Enhanced Vaccine Escape Potential After 13-Valent Pneumococcal Conjugate Vaccine Introduction 引入13价肺炎球菌结合疫苗后，具有增强的疫苗逃逸潜力的肺炎链球菌血清型3荚膜变异序列700型的克隆扩增 Kalizang'oma, Akuzike; Swarthout, Todd D.; Mwalukomo, Thandie S.; Kamng'ona, Arox; Brown, Comfort; Msefula, Jacquline; Demetriou, Hayley; Chan, Jia Mun; Roalfe, Lucy; Obolski, Uri; Lourenco, Jose; Goldblatt, David; Chaguza, Chrispin; French, Neil; Heyderman, Robert S. 分享 收藏
Efficacy of typhoid conjugate vaccine: final analysis of a 4-year, phase 3, randomised controlled trial in Malawian children Patel, Priyanka D.; Liang, Yuanyuan; Meiring, James E.; Chasweka, Nedson; Patel, Pratiksha; Misiri, Theresa; Mwakiseghile, Felistas; Wachepa, Richard; Banda, Happy C.; Shumba, Florence; Kawalazira, Gift; Dube, Queen; Nampota-Nkomba, Nginache; Nyirenda, Osward M.; Girmay, Tsion; Datta, Shrimati; Jamka, Leslie P.; Tracy, J. Kathleen; Laurens, Matthew B.; Heyderman, Robert S.; Neuzil, Kathleen M.; Gordon, Melita A. 分享 收藏
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The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi 在马拉维城市引入PCV13后，肺炎链球菌的代谢，毒力和抗菌素耐药性转移 Obolski, Uri; Swarthout, Todd D.; Kalizang'oma, Akuzike; Mwalukomo, Thandie S.; Chan, Jia Mun; Weight, Caroline M.; Brown, Comfort; Cave, Rory; Cornick, Jen; Kamng'ona, Arox Wadson; Msefula, Jacquline; Ercoli, Giuseppe; Brown, Jeremy S.; Lourenco, Jose; Maiden, Martin C.; French, Neil; Gupta, Sunetra; Heyderman, Robert S. 分享 收藏
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge 使用人感染攻击对毒力减毒的肺炎链球菌菌株进行鼻腔预防接种的随机对照临床试验 Hill, Helen; Mitsi, Elena; Nikolaou, Elissavet; Blizard, Annie; Pojar, Sherin; Howard, Ashleigh; Hyder-Wright, Angela; Devin, Jack; Reine, Jesus; Robinson, Ryan; Solorzano, Carla; Jochems, Simon P.; Kenny-Nyazika, Tinashe; Ramos-Sevillano, Elisa; Weight, Caroline M.; Myerscough, Chris; McLenaghan, Daniella; Morton, Ben; Gibbons, Emily; Farrar, Madlen; Randles, Victoria; Burhan, Hassan; Chen, Tao; Shandling, Adam D.; Campo, Joe J.; Heyderman, Robert S.; Gordon, Stephen B.; Brown, Jeremy S.; Collins, Andrea M.; Ferreira, Daniela M. 分享 收藏
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