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M

Mark S. Cragg

University of Southampton

67H指数
402论文数
2.1W被引数
收录论文 141
发表时间
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Deletion or immunotherapeutic blockade of FcγRIIb (CD32b) impairs α-Syn propagation in vivo删除或免疫治疗性阻断FcγRIIb（CD32b）会损害α-突触核蛋白在体内的传播
errActa Neuropathologica
IF9.3
err2026-09-25
err0
errOAAI
errJames M. Hennegan; Michael J. Hurley; Matthew Colley; Kerry L. Cox; Leon R. Douglas; Patrick J. Duriez; Robert J. Oldham; Mark S. Cragg; Björn Frendéus; Ali Roghanian; Jessica L. Teeling
err分享
err收藏
Gas-phase unfolding assay rapidly predicts structure-function relationships in engineered antibodies with tuned flexibilities气相展开分析可快速预测具有调节柔韧性的工程抗体的构象-功能关系
errNature Communications
IF15.7
err2026-06-29
err0
errOAAI
errRosendo C. Villafuerte-Vega; Michael R. Armbruster; Hayden Fisher; Isabel G. Elliott; H. T. Claude Chan; Tatyana Inzhelevskaya; C. Ian Mockridge; Christine A. Penfold; Patrick J. Duriez; Mark S. Cragg; Brandon T. Ruotolo
err分享
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Realizing the potential of agonistic antibody immunotherapy实现激动性抗体免疫治疗的潜力
errNature Reviews Drug Discovery
IF101.8
err2026-05-19
err0
PREAI
errMark S. Cragg; Xiaojie Yu; Christopher Paluch; Simon J. Davis
err分享
err收藏
Tumor-associated CD47 regulation of the phagocyte oxidase shapes innate and adaptive immune responses during anti-tumor antibody therapy
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errHoppe, Adam D.; Sharma, Pratibha; Beers, Stephen A.; Cragg, Mark S.
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Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism结构指导的二硫键工程限制抗体构象以诱导TNFR激动作用
errNATURE COMMUNICATIONS
IF15.7
err2025-04-12
err0
errOAAI
errElliott, Isabel G.; Fisher, Hayden; Chan, H. T. Claude; Inzhelevskaya, Tatyana; Mockridge, C. Ian; Penfold, Christine A.; Duriez, Patrick J.; Orr, Christian M.; Herniman, Julie; Muller, Kri T. J.; Essex, Jonathan W.; Cragg, Mark S.; Tews, Ivo
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FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRsFcγRIIB (CD32B)抗体通过激活FcγR来增强免疫反应。
errCLINICAL AND EXPERIMENTAL IMMUNOLOGY
IF3.8
err2025-03-16
err0
errOAAI
errSimpson, Alexander P.; Oldham, Robert J.; Cox, Kerry L.; Taylor, Martin C.; James, Sonya; White, Ann L.; Bogdanov, Yury; Glennie, Martin J.; Frendeus, Bjoern; Cragg, Mark S.; Roghanian, Ali
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Therapeutic targeting of tumour-associated macrophage receptors靶向肿瘤相关巨噬细胞受体的治疗策略
errIMMUNOTHERAPY ADVANCES
IF4.9
err2025-03-11
err0
errOAAI
errMartins, Rosa Gomes Alves; Tekin, Mehmet M.; Cragg, Mark S.; Roghanian, Ali
err分享
err收藏
The complement system in clinical oncology: Applications, limitations and challenges补体系统在临床肿瘤学中的应用、局限与挑战
errSEMINARS IN IMMUNOLOGY
IF7.8
err2025-03-01
err0
errOAAI
errAjona, Daniel; Cragg, Mark S.; Pio, Ruben
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The ETS-family transcription factor PU.1 is a critical regulator of the inhibitory Fcγ receptor IIB expression in humansETS家族转录因子PU.1是人类抑制性Fcγ受体IIB表达的关键调控因子。
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-02-26
err0
errOAAI
errCarter, Matthew J.; Bogdanov, Yury D.; Smith, Rosanna C.; Cox, Kerry L.; Frampton, Sarah; Ferson, Lili; Foxall, Russel B.; Hussain, Khiyam; Strefford, Jonathan C.; Beers, Stephen A.; Cragg, Mark S.
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CD40L and IL-4 suppress NK cell-mediated antibody-dependent cellular cytotoxicity through the HLA-E:NKG2A axisCD40L和IL-4通过hla-e: NKG2A轴抑制NK细胞介导的抗体依赖性细胞毒性
errIMMUNOTHERAPY ADVANCES
IF4.9
err2025-01-01
err0
errOAAI
errGraham, Lara, V; Horehajova, Ludmila; Haselager, Marco, V; Fisher, Jack G.; Roos, Jamie Lee; Foxall, Russell B.; John, Mel; Cox, Kerry L.; Oldham, Robert J.; Taylor, Martin C.; Ashton-Key, Margaret; Sale, Ben; Bartlett, Laura G.; Roghanian, Ali; Eldering, Eric; Vallejo, Andres F.; Forconi, Francesco; Khakoo, Salim, I; Cragg, Mark S.; Blunt, Matthew D.
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Downhill running does not alter blood C1q availability or complement-dependent cytotoxicity of therapeutic monoclonal antibodies against haematological cancer cell lines in vitro
errSCIENTIFIC REPORTS
IF3.9
err2024-11-15
err0
errOAAI
errCollier-Bain, Harrison D.; Brown, Frankie F.; Causer, Adam J.; Ross, Lois; Rothschild-Rodriguez, Daniela; Browne, Noah; Eddy, Rachel; Cleary, Kirstie L.; Gray, Juliet C.; Cragg, Mark S.; Moore, Sally; Murray, James; Turner, James E.; Campbell, John P.
err分享
err收藏
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease
errIMMUNOLOGICAL REVIEWS
IF8.3
err2024-09-30
err0
errOAAI
errFrampton, Sarah; Smith, Rosanna; Ferson, Lili; Gibson, Jane; Hollox, Edward J.; Cragg, Mark S.; Strefford, Jonathan C.
err分享
err收藏
KIR2DS2+NK cells in cancer patients demonstrate high activation in response to tumour-targeting antibodies
errFRONTIERS IN ONCOLOGY
IF3.3
err2024-09-02
err0
errOAAI
errGraham, Lara V.; Fisher, Jack G.; Doyle, Amber D. P.; Sale, Ben; Del Rio, Luis; French, Albert J. E.; Mayor, Neema P.; Turner, Thomas R.; Marsh, Steven G. E.; Cragg, Mark S.; Forconi, Francesco; Khakoo, Salim I.; Blunt, Matthew D.
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Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity
errSCIENCE IMMUNOLOGY
IF16.3
err2024-07-19
err0
errOAAI
errStockis, Julie; Yip, Thomas; Moreno-Vicente, Julia; Burton, Oliver; Samarakoon, Youhani; Schuijs, Martijn J.; Raghunathan, Shwetha; Garcia, Celine; Luo, Weike; Whiteside, Sarah K.; Png, Shaun; Simpson, Charlotte; Monk, Stela; Sawle, Ashley; Yin, Kelvin; Barbieri, Johanna; Papadopoulos, Panagiotis; Wong, Hannah; Rodewald, Hans-Reimer; Vyse, Timothy; McKenzie, Andrew N. J.; Cragg, Mark S.; Hoare, Matthew; Withers, David R.; Fehling, Hans Joerg; Roychoudhuri, Rahul; Liston, Adrian; Halim, Timotheus Y. F.
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Impact of isotype on the mechanism of action of agonist anti-OX40 antibodies in cancer: implications for therapeutic combinations同种型对激动剂anti-OX40抗体在癌症中的作用机制的影响: 对治疗组合的影响
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2024-07-04
err0
errOAAI
errWilloughby, Jane E.; Dou, Lang; Bhattacharya, Sabyasachi; Jackson, Heather; Seestaller-Wehr, Laura; Kilian, David; Bover, Laura; Voo, Kui S.; Cox, Kerry L.; Murray, Tom; John, Mel; Shi, Hong; Bojczuk, Paul; Jing, Junping; Niederer, Heather; Shepherd, Andrew J.; Hook, Laura; Hopley, Stephanie; Inzhelevskaya, Tatyana; Penfold, Chris A.; Mockridge, C. Ian; English, Vikki; Brett, Sara J.; Srinivasan, Roopa; Hopson, Christopher; Smothers, James; Hoos, Axel; Paul, Elaine; Martin, Stephen L.; Morley, Peter J.; Yanamandra, Niranjan; Cragg, Mark S.
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A single bout of vigorous intensity exercise enhances the efficacy of rituximab against human chronic lymphocytic leukaemia B-cells ex vivo
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2024-05-01
err3
errOAAI
errCollier-Bain, Harrison D.; Emery, Annabelle; Causer, Adam J.; Brown, Frankie F.; Oliver, Rebecca; Dutton, David; Crowe, Josephine; Augustine, Daniel; Graby, John; Leach, Shoji; Eddy, Rachel; Rothschild-Rodriguez, Daniela; Gray, Juliet C.; Cragg, Mark S.; Cleary, Kirstie L.; Moore, Sally; Murray, James; Turner, James E.; Campbell, John P.
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Disrupting B and T-cell collaboration in autoimmune disease: T-cell engagers versus CAR T-cell therapy?在自身免疫性疾病中破坏b细胞和T细胞的合作: T细胞接合器与CAR T细胞疗法？
errCLINICAL AND EXPERIMENTAL IMMUNOLOGY
IF3.8
err2024-04-20
err6
errOAAI
errShah, Kavina; Leandro, Maria; Cragg, Mark; Kollert, Florian; Schuler, Franz; Klein, Christian; Reddy, Venkat
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err收藏
MicroRNA manipulation of macrophage polarization in DLBCL to augment antibody immunotherapy
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errLongley, Jemma; Foxall, Russell; Thirdborough, Steven; Beers, Steve; Cragg, Mark
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err收藏
Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity
errMOLECULAR THERAPY
IF12
err2024-02-01
err11
errOAAI
errKennedy, Paul T.; Saulters, Emma L.; Duckworth, Andrew D.; Lim, Yeong Jer; Woolley, John F.; Slupsky, Joseph R.; Cragg, Mark S.; Ward, Frank J.; Dahal, Lekh N.
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Agonist Antibodies for Cancer Immunotherapy: History, Hopes, and Challenges癌症免疫治疗的激动剂抗体: 历史，希望和挑战
errCLINICAL CANCER RESEARCH
IF10.2
err2023-12-28
err2
errOAAI
errLim, Sean H.; Beers, Stephen A.; Al-Shamkhani, Aymen; Cragg, Mark S.
err分享
err收藏

研究方向

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合作学者
合作期刊
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Brian Druker
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H 指数: 126 · 论文数: 1.2K
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V. Hugh Perry
H 指数: 119 · 论文数: 428
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John G. Gribben
H 指数: 115 · 论文数: 873
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