Laura T. Donlin - Publications, H-index & Citations

Laura T. Donlin

weill cornell graduate school

33H指数

127论文数

1.0W被引数

收录论文 45

发表时间

SPP1hi macrophages in fibrin niches promote hyperplastic tissue remodeling in rheumatoid arthritis synovium 高SPP1表达巨噬细胞在纤维蛋白微环境中促进类风湿关节炎滑膜组织的增生性重塑

Science Translational Medicine

IF14.6

2026-06-24

PREAI

Ian Mantel; Haoxuan Zhang; Juan Vargas; Gao Ce; Hope Townsend; Richard Bell; Amit Lakhanpal; Miriam R. Fein; ; Thomas M. Norman; Dana E. Orange; Daniel C. Ramirez; Edward F. DiCarlo; Susan M. Goodman; Melanie H. Smith; Fan Zhang; Kevin Wei; Kushal K. Dey; Alexander Y. Rudensky; Christina S. Leslie; Laura T. Donlin

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases RA和其他自身免疫性关节炎疾病中人体组织中的功能和功能失调的T调节细胞状态

Nature Immunology

IF27.6

2026-06-16

PREAI

Byunghee Koh; Shani T. Gal Oz; Ryota Sato; Hung N. Nguyen; Garrett Dunlap; Christopher Mahony; Chrissy Bolton; Lucy R. Wedderburn; Adam P. Croft; Laura Donlin; Melanie H. Smith; Soumya Raychaudhuri; Ilya Korsunsky; Deepak A. Rao; Michael B. Brenner

Pretreatment naive Tcells are associated with severe irAE following PD-1/CTLA-4 checkpoint blockade for melanoma 治疗前naïve T细胞与黑色素瘤PD-1/CTLA4检查点阻断后严重irAE相关

JCI Insight

IF6.1

2026-01-23

PREAI

Marks, Kathryne E.; Horisberger, Alice; Elahee, Mehreen; Adejoorin, Ifeoluwakiisi A.; Ghosh, Nilasha; Postow, Michael; Donlin, Laura; Bass, Anne R.; Rao, Deepak A.

Rheumatoid arthritis synovial fibroblasts modulate T cell activation 类风湿关节炎滑膜成纤维细胞调节T细胞活化

JCI INSIGHT

IF6.1

2025-11-24

OAAI

Romoff, Melissa R.; Periyakoil, Preethi K.; Dicarlo, Edward F.; Ramirez, Daniel; Goodman, Susan M.; Leslie, Christina S.; Rudensky, Alexander Y.; Donlin, Laura T.; Smith, Melanie H.

Antigen-specific B cells cross-present citrullinated proteins to activate CD8 T cells in rheumatoid arthritis

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Moon, Jae Seung; Van Dam, Laura; Smith, Melanie; Donlin, Laura T.; Sharpe, Orr; Robinson, William H.

Characterizing molecular targets in difficult-to-treat rheumatoid arthritis 表征难治性类风湿关节炎的分子靶点

SEMINARS IN ARTHRITIS AND RHEUMATISM

IF4.4

2025-02-01

PREAI

Smith, Melanie H.; Bai, Zilong; Lakhanpal, Amit; Ramirez, Daniel; Dicarlo, Edward; Donlin, Laura; Orange, Dana; Goodman, Susan M.

Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis 通过CDK7抑制破坏RNA聚合酶II转录周期可改善炎症性关节炎

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-11-20

PREAI

Chen, Xi; Shibu, Gayathri; Sokolsky, Baila A.; Soussana, Tamar Nicole; Fisher, Logan; Deochand, Dinesh K.; Dacic, Marija; Mantel, Ian; Ramirez, Daniel C.; Bell, Richard D.; Zhang, Tinghu; Donlin, Laura T.; Goodman, Susan M.; Gray, Nathanael S.; Chinenov, Yurii; Fisher, Robert P.; Rogatsky, Inez

Are There Disease Endotypes in Axial Spondyloarthritis and How Would We Define Them?中轴型脊柱关节炎是否存在疾病类型？我们如何定义它们？

JOURNAL OF RHEUMATOLOGY

IF3.4

2024-10-24

OAAI

Deane, Kevin D.; Donlin, Laura T.; Ritchlin, Christopher T.; Kuhn, Kristine A.

IL-6 receptor blockade prevents polarization of pro-fibrotic macrophages in myeloid-rich RA synovial tissue

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

PREAI

Mantel, Ian; Singaraju, Anvita; Townsend, Hope; Lakhanpal, Amit; Zhang, Fan; Donlin, Laura

Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles 来自多模态单细胞数据的组织特异性增强子基因图谱可识别致病等位基因

NATURE GENETICS

IF31.8

2024-04-09

OAAI

Sakaue, Saori; Weinand, Kathryn; Isaac, Shakson; Dey, Kushal K.; Jagadeesh, Karthik; Kanai, Masahiro; Watts, Gerald F. M.; Zhu, Zhu; Brenner, Michael B.; McDavid, Andrew; Donlin, Laura T.; Wei, Kevin; Price, Alkes L.; Raychaudhuri, Soumya

Associations Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Types and States

ARTHRITIS & RHEUMATOLOGY

IF10.9

2024-01-19

OAAI

Weisenfeld, Dana; Zhang, Fan; Donlin, Laura; Jonsson, Anna Helena; Apruzzese, William; Campbell, Debbie; Rao, Deepak A.; Wei, Kevin; Holers, V. Michael; Gravallese, Ellen; Moreland, Larry; Goodman, Susan; Brenner, Michael; Raychaudhuri, Soumya; Filer, Andrew; Anolik, Jennifer; Bykerk, Vivian; Liao, Katherine P.

Computer Vision Analysis of Rheumatoid Arthritis Synovium Reveals Lymphocytic Inflammation Is Associated With Immunoglobulin Skewing in Blood

ARTHRITIS & RHEUMATOLOGY

IF10.9

2023-11-15

OAAI

Frezza, Damon; DiCarlo, Edward; Hale, Caryn; Ramirez, Daniel; Mehta, Bella; Slater, David; Habib, Saimun; Frank, Mayu O.; Spolaore, Edoardo; Smith, Melanie H.; Donlin, Laura; Goodman, Susan; Thompson, James R.; Orange, Dana E.

Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis

SCIENCE IMMUNOLOGY

IF16.3

2023-07-28

OAAI

Wang, Runci; Singaraju, Anvita; Marks, Kathryne E.; Shakib, Lorien; Dunlap, Garrett; Adejoorin, Ifeoluwakiisi; Greisen, Stinne R.; Chen, Lin; Tirpack, Aidan K.; Aude, Carlos; Fein, Miriam R.; Todd, Derrick J.; MacFarlane, Lindsey; Goodman, Susan M.; DiCarlo, Edward F.; Massarotti, Elena M.; Sparks, Jeffrey A.; Jonsson, A. Helena; Brenner, Michael B.; Postow, Michael A.; Chan, Karmela K.; Bass, Anne R.; Donlin, Laura T.; Rao, Deepak A.

Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis

NATURE IMMUNOLOGY

IF27.6

2023-06-05

OAAI

Smith, Melanie H.; Gao, Vianne R.; Periyakoil, Preethi K.; Kochen, Alejandro; DiCarlo, Edward F.; Goodman, Susan M.; Norman, Thomas M.; Donlin, Laura T.; Leslie, Christina S.; Rudensky, Alexander Y.

Emerging synovial cell states in rheumatoid arthritis as potential therapeutic targets

CURRENT OPINION IN RHEUMATOLOGY

IF4.3

2023-04-07

PREAI

Mantel, Ian; Fein, Miriam R.; Donlin, Laura T.

The adapter molecule sin regulates T-cell-receptor-mediated signal transduction by modulating signaling substrate availability

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Xing, LZ; Donlin, LT; Miller, RH; Alexandropoulos, K

Deficiency in expression of the signaling protein Sin/Efs leads to T-lymphocyte activation and mucosal inflammation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Donlin, LT; Danzl, NM; Wanjalla, C; Alexandropoulos, K

Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis

NATURE COMMUNICATIONS

IF15.7

2023-01-19

OAAI

Moon, Jae-Seung; Younis, Shady; Ramadoss, Nitya S.; Iyer, Radhika; Sheth, Khushboo; Sharpe, Orr; Rao, Navin L. L.; Becart, Stephane; Carman, Julie A.; James, Eddie A.; Buckner, Jane H.; Deane, Kevin D.; Holers, V. Michael; Goodman, Susan M.; Donlin, Laura T.; Davis, Mark M.; Robinson, William H.

Inching closer to precision treatment for rheumatoid arthritis

NATURE MEDICINE

IF50

2022-06-09

PREAI

Donlin, Laura T.

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression 以NR4A核受体表达为特征的RA滑膜中异位淋巴b细胞活化和超突变的动态谱

CELL REPORTS

IF6.9

2022-05-01

OAAI

Meednu, Nida; Rangel-Moreno, Javier; Zhang, Fan; Escalera-Rivera, Katherine; Corsiero, Elisa; Prediletto, Edoardo; DiCarlo, Edward; Goodman, Susan; Donlin, Laura T.; Raychauduri, Soumya; Bombardieri, Michele; Pitzalis, Costantino; Orange, Dana E.; McDavid, Andrew; Anolik, Jennifer H.

研究方向