Cheung, Belamy B.; Mittra, Ritu; Murray, Jayne; Wang, Qian; Seneviratne, Janith A.; Raipuria, Mukesh; Wong, Iris Poh Ling; Restuccia, David; Gifford, Andrew; Salib, Alice; Sutton, Selina; Huang, Libby; Ferdowsi, Parisa Vahidi; Tsang, Joanna; Sekyere, Eric; Mayoh, Chelsea; Luo, Lin; Brown, Darren L.; Stow, Jennifer L.; Zhu, Shizhen; Young, Richard J.; Solomon, Benjamin J.; Chappaz, Stephane; Kile, Benjamin; Kueh, Andrew; Herold, Marco J.; Hilton, Douglas J.; Liu, Tao; Norris, Murray D.; Haber, Michelle; Carter, Daniel R.; Parker, Michael W.; Marshall, Glenn M.

Multiorgan locked-state model of chronic diseases and systems pharmacology opportunities

DRUG DISCOVERY TODAY

IF7.5

2024-01-011

OAAI

Network Biology-Inspired Machine Learning Features Predict Cancer Gene Targets and Reveal Target Coordinating Mechanisms

PHARMACEUTICALS

IF4.8

2023-05-162

OAAI

A Knowledge-Based Discovery Approach Couples Artificial Neural Networks With Weight Engineering to Uncover Immune-Related Processes Underpinning Clinical Traits of Breast Cancer

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-144

OAAI

Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma

CANCER RESEARCH

IF16.6

2021-07-0736

Zebrafish as a Neuroblastoma Model: Progress Made, Promise for the Future

CELLS

IF5.2

2021-03-0610

OAAI

A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma

ONCOGENE

IF7.3

2021-03-0316

OAAI

GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma

CANCER RESEARCH

IF16.6

2021-02-1816

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

CANCER RESEARCH

IF16.6

2019-11-0126

OAAI

Koach, Jessica; Holien, Jessica K.; Massudi, Hassina; Carter, Daniel R.; Ciampa, Olivia C.; Herath, Mika; Lim, Taylor; Seneviratne, Janith A.; Milazzo, Giorgio; Murray, Jayne E.; McCarroll, Joshua A.; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W.; Gorman, Michael A.; Bell, Jessica L.; Doughty, Larissa; Huettelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J.; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W. Clay; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie I.; Perini, Giovanni; Parker, Michael W.; Cheung, Belamy B.; Marshall, Glenn M.

Loss of function of GAS7 promotes neuroblastoma metastasis in the context of MYCN overexpression

CANCER RESEARCH

IF16.6

2019-07-010

PRE

MYC activation through enhancer hijacking or focal enhancer amplification drives a subset of high-risk pediatric neuroblastoma

CANCER RESEARCH

IF16.6

2018-10-010

PRE

c-MYC drives a subset of high-risk pediatric neuroblastoma and is activated through mechanisms including enhancer hijacking and focal enhancer amplification

CANCER RESEARCH