Richard J. Goodyear - Publications, H-index & Citations

Richard J. Goodyear

university of sussex

45H指数

86论文数

6.1K被引数

收录论文 22

发表时间

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non-Syndromic Hearing Loss TECTB变异揭示显性非综合征性听力损失中盖膜易损性

Advanced Science

IF14.1

2026-09-07

OAAI

Evan B. Hale; Barbara Vona; Richard J. Goodyear; Richard T. Osgood; Jun Shen; Sami S. Amr; Karen Mojica; Michaela A. H. Hofrichter; Jörg Schröder; Sophie Flandin; Paul Gratias; Ricardo Vera-Monroy; Katherine Callahan; Kerry L. Gudlewski; Rolen Quadros; Masato Ohtsuka; JoAnn McGee; Edward J. Walsh; Cynthia C. Morton; Thomas Haaf; Channabasavaiah Gurumurthy; James E. Saunders; Guy P. Richardson; Artur A. Indzhykulian

Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity

JCI INSIGHT

IF6.1

2021-04-08

OAAI

Kenyon, Emma J.; Kirkwood, Nerissa K.; Kitcher, Sian R.; Goodyear, Richard J.; Derudas, Marco; Cantillon, Daire M.; Baxendale, Sarah; de Leon, Antonio de la Vega; Mahieu, Virginia N.; Osgood, Richard T.; Wilson, Charlotte Donald; Bull, James C.; Waddell, Simon J.; Whitfield, Tanya T.; Ward, Simon E.; Kros, Corne J.; Richardson, Guy P.

Accelerated Age-Related Degradation of the Tectorial Membrane in the Ceacam16βgal/βgal Null Mutant Mouse, a Model for Late-Onset Human Hereditary Deafness DFNB113 Ceacam16βgal/β gal无效突变小鼠中与年龄相关的盖膜降解加速，这是一种迟发性人类遗传性耳聋DFNB113的模型

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2019-06-12

OAAI

Goodyear, Richard J.; Cheatham, Mary Ann; Naskar, Souvik; Zhou, Yingjie; Osgood, Richard T.; Zheng, Jing; Richardson, Guy P.

Identification of ion-channel modulators that protect against aminoglycosideinduced hair cell death

JCI INSIGHT

IF6.1

2017-12-21

OAAI

Kenyon, Emma J.; Kirkwood, Nerissa K.; Kitcher, Sian R.; O'Reilly, Molly; Derudas, Marco; Cantillon, Daire M.; Goodyear, Richard J.; Secker, Abigail; Baxendale, Sarah; Bull, James C.; Waddell, Simon J.; Whitfield, Tanya T.; Ward, Simon E.; Kros, Corne J.; Richardson, Guy P.

Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning

DEVELOPMENTAL CELL

IF8.7

2017-03-01

147

OAAI

Shaya, Oren; Binshtok, Udi; Hersch, Micha; Rivkin, Dmitri; Weinreb, Sheila; Amir-Zilberstein, Liat; Khamaisi, Bassma; Oppenheim, Olya; Desai, Ravi A.; Goodyear, Richard J.; Richardson, Guy P.; Chen, Christopher S.; Sprinzak, David

A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane

DEVELOPMENT

IF3.6

2017-01-01

OAAI

Goodyear, Richard J.; Lu, Xiaowei; Deans, Michael R.; Richardson, Guy P.

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells

EMBO MOLECULAR MEDICINE

IF8.3

2014-06-17

OAAI

Pepermans, Elise; Michel, Vincent; Goodyear, Richard; Bonnet, Crystel; Abdi, Samia; Dupont, Typhaine; Gherbi, Souad; Holder, Muriel; Makrelouf, Mohamed; Hardelin, Jean-Pierre; Marlin, Sandrine; Zenati, Akila; Richardson, Guy; Avan, Paul; Bahloul, Amel; Petit, Christine

Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane

HUMAN MOLECULAR GENETICS

IF3.2

2013-12-20

OAAI

Legan, P. Kevin; Goodyear, Richard J.; Morin, Matias; Mencia, Angeles; Pollard, Hilary; Olavarrieta, Leticia; Korchagina, Julia; Modamio-Hoybjor, Silvia; Mayo, Fernando; Moreno, Felipe; Moreno-Pelayo, Miguel-Angel; Richardson, Guy P.

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-08-05

OAAI

Furness, David N.; Johnson, Stuart L.; Manor, Uri; Ruettiger, Lukas; Tocchetti, Arianna; Offenhauser, Nina; Olt, Jennifer; Goodyear, Richard J.; Vijayakumar, Sarath; Dai, Yuhai; Hackney, Carole M.; Franz, Christoph; Di Fiore, Pier Paolo; Masetto, Sergio; Jones, Sherri M.; Knipper, Marlies; Holley, Matthew C.; Richardson, Guy P.; Kachar, Bechara; Marcotti, Walter

A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-11-05

OAAI

Lukashkin, Andrei N.; Legan, P. Kevin; Weddell, Thomas D.; Lukashkina, Victoria A.; Goodyear, Richard J.; Welstead, Lindsey J.; Petit, Christine; Russell, Ian J.; Richardson, Guy P.

A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2012-11-01

OAAI

von Ameln, Simon; Wang, Geng; Boulouiz, Redouane; Rutherford, Mark A.; Smith, Geoffrey M.; Li, Yun; Pogoda, Hans-Martin; Nuernberg, Gudrun; Stiller, Barbara; Volk, Alexander E.; Borck, Guntram; Hong, Jason S.; Goodyear, Richard J.; Abidi, Omar; Nuernberg, Peter; Hofmann, Kay; Richardson, Gu Y. P.; Hammerschmidt, Matthias; Moser, Tobias; Wollnik, Bernd; Koehler, Carla M.; Teitell, Michael A.; Barakat, Abdelhamid; Kubisch, Christian

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-03-21

122

OAAI

Caberlotto, Elisa; Michel, Vincent; Foucher, Isabelle; Bahloul, Amel; Goodyear, Richard J.; Pepermans, Elise; Michalski, Nicolas; Perfettini, Isabelle; Alegria-Prevot, Olinda; Chardenoux, Sebastien; Do Cruzeiro, Marcio; Hardelin, Jean-Pierre; Richardson, Guy P.; Avan, Paul; Weil, Dominique; Petit, Christine

Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with α-tectorin and is mutated in autosomal dominant hearing loss (DFNA4)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-02-22

105

OAAI

Zheng, Jing; Miller, Katharine K.; Yang, Tao; Hildebrand, Michael S.; Shearer, A. Eliot; DeLuca, Adam P.; Scheetz, Todd E.; Drummond, Jennifer; Scherer, Steve E.; Legan, P. Kevin; Goodyear, Richard J.; Richardson, Guy P.; Cheatham, Mary Ann; Smith, Richard J.; Dallos, Peter

In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment 导致DFNA20/26听力障碍的两种新型 γ-肌动蛋白 (ACTG1) 突变的体内和体外作用

HUMAN MOLECULAR GENETICS

IF3.2

2009-05-28

OAAI

Morin, Matias; Bryan, Keith E.; Mayo-Merino, Fernando; Goodyear, Richard; Mencia, Angeles; Modamio-Hoybjor, Silvia; del Castillo, Ignacio; Cabalka, Jessica M.; Richardson, Guy; Moreno, Felipe; Rubenstein, Peter A.; Angel Moreno-Pelayo, Miguel

A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2007-06-01

OAAI

Modamio-Hoybjor, Silvia; Mencia, Angeles; Goodyear, Richard; del Castillo, Ignacio; Richardson, Guy; Moreno, Felipe; Moreno-Pelayo, Miguel Angel

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly

HUMAN MOLECULAR GENETICS

IF3.2

2004-12-08

182

PREAI

Delprat, B; Michel, V; Goodyear, R; Yamasaki, Y; Michalski, N; El-Amraoui, A; Perfettini, I; Legrain, P; Richardson, G; Hardelin, JP; Petit, C

The structure of tip links and kinocilial links in avian sensory hair bundles

BIOPHYSICAL JOURNAL

IF3.1

2004-12-01

OAAI

Tsuprun, V; Goodyear, RJ; Richardson, GP

Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2004-03-01

212

OAAI

Ng, L; Goodyear, RJ; Woods, CA; Schneider, MJ; Diamond, E; Richardson, GP; Kelley, MW; St Germain, DL; Galton, VA; Forrest, D

Sensory organ development in the inner ear: molecular and cellular mechanisms

BRITISH MEDICAL BULLETIN

IF5.2

2002-10-01

104

OAAI

Bryant, J; Goodyear, RJ; Richardson, GP

Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2002-04-23

148

OAAI

Zwaenepoel, I; Mustapha, M; Leibovici, M; Verpy, E; Goodyear, R; Liu, XZ; Nouaille, S; Nance, WE; Kanaan, M; Avraham, KB; Tekaia, F; Loiselet, J; Lathrop, M; Richardson, G; Petit, C

研究方向