Keith B. Elkon - Publications, H-index & Citations

Keith B. Elkon

university of washington

80H指数

280论文数

2.3W被引数

收录论文 96

发表时间

Single-cell and spatial transcriptomics implicate vascular cell orchestration of inflammatory changes after UV light exposure in skin 单细胞和空间转录组学揭示UV光照射后皮肤中血管细胞对炎症变化的调控

Journal of Investigative Dermatology

IF5.7

2025-12-17

PREAI

Jie An; Rachael Bogle; Rayan Najjar; Lam C. Tsoi; J. Michelle Kahlenberg; Ksenia Anufrieva; Erin Theisen; Kevin Wei; Johann E. Gudjonsson; Keith B. Elkon

Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids

JOURNAL OF LIPID RESEARCH

IF4.1

2025-01-01

OAAI

Barnhart, Shelley; Shimizu-Albergine, Masami; Kedar, Eyal; Kothari, Vishal; Shao, Baohai; Krueger, Melissa; Hsu, Cheng-Chieh; Tang, Jingjing; Kanter, Jenny E.; Kramer, Farah; Djukovic, Danijel; Pascua, Vadim; Loo, Yueh-Ming; Colonna, Lucrezia; Van den Bogaerde, Sadie J.; An, Jie; Gale Jr, Michael; Reue, Karen; Fisher, Edward A.; Gharib, Sina A.; Elkon, Keith B.; Bornfeldt, Karin E.

B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease 树突状细胞、单核细胞和中性粒细胞来源的B细胞活化因子（BAFF）是系统性红斑狼疮样自身免疫性疾病中B细胞成熟和自身抗体产生的必要条件。

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-02-27

OAAI

Giordano, Daniela; Kuley, Runa; Draves, Kevin E.; Elkon, Keith B.; Giltiay, Natalia V.; Clark, Edward A.

Role of the cGAS-STING pathway in systemic and organ-specific diseases

NATURE REVIEWS NEPHROLOGY

IF39.8

2022-06-22

119

OAAI

Skopelja-Gardner, Sladjana; An, Jie; Elkon, Keith B.

Acute skin exposure to ultraviolet light triggers neutrophil-mediated kidney inflammation 急性皮肤暴露于紫外线会引发中性粒细胞介导的肾脏炎症

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-04

OAAI

Skopelja-Gardner, Sladjana; Tai, Joyce; Sun, Xizhang; Tanaka, Lena; Kuchenbecker, James A.; Snyder, Jessica M.; Kubes, Paul; Mustelin, Tomas; Elkon, Keith B.

The (Orf)ull truth about IRF5 and type I interferons in SLE

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2020-07-24

PREAI

Elkon, Keith B.; Briggs, Tracy A.

Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury

JOURNAL OF IMMUNOLOGY

IF3.4

2020-05-15

OAAI

Skopelja-Gardner, Sladjana; Colonna, Lucrezia; Hermanson, Payton; Sun, Xizhang; Tanaka, Lena; Tai, Joyce; Nguyen, Yenly; Snyder, Jessica M.; Alpers, Charles E.; Hudkins, Kelly L.; Salant, David J.; Peng, YuFeng; Elkon, Keith B.

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

SCIENTIFIC REPORTS

IF3.9

2020-05-13

OAAI

Skopelja-Gardner, Sladjana; An, Jie; Tai, Joyce; Tanaka, Lena; Sun, Xizhang; Hermanson, Payton; Baum, Rebecca; Kawasumi, Masaoki; Green, Richard; Gale, Michael, Jr.; Kalus, Andrea; Werth, Victoria P.; Elkon, Keith B.

Georgia abortion law and our commitment to patients

ARTHRITIS & RHEUMATOLOGY

IF10.9

2019-12-29

OAAI

Craft, Joseph E.; Crow, Mary K.; Lockshin, Michael D.; Salmon, Jane E.; Diamond, Betty; Elkon, Keith B.; Flood, Joseph; Fox, David A.; Gabriel, Sherine E.; Gilkeson, Gary S.; Hahn, Bevra H.; Hardin, John; Koopman, William J.; Seaman, William E.; Wofsy, David; Sergent, John S.; Uknis, Audrey B.; Weinblatt, Michael E.

High TLR7 Expression Drives the Expansion of CD19+CD24hiCD38hi Transitional B Cells and Autoantibody Production in SLE Patients 高TLR7表达驱动SLE患者CD19 CD24hiCD38hi过渡b细胞的扩增和自身抗体的产生

FRONTIERS IN IMMUNOLOGY

IF5.9

2019-06-04

OAAI

Wang, Ting; Marken, John; Chen, Janice; Van Bao Tran; Li, Quan-Zhen; Li, Mengtao; Cerosaletti, Karen; Elkon, Keith B.; Zeng, Xiaofeng; Giltiay, Natalia V.

Aspirin meets cGAS

NATURE REVIEWS RHEUMATOLOGY

IF32.7

2019-03-26

PREAI

Elkon, Keith B.

Inhibition of Cyclic GMP-AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1-Deficient Mice

ARTHRITIS & RHEUMATOLOGY

IF10.9

2018-09-14

PREAI

An, Jie; Woodward, Joshua J.; Lai, Weinan; Minie, Mark; Sun, Xizhang; Tanaka, Lena; Snyder, Jessica M.; Sasaki, Tomikazu; Elkon, Keith B.

The role of interferon and retroelements in lupus-prone Ro60 knockout mouse skin

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2018-05-01

OAAI

Rokunohe, D.; Chiou, E.; Sun, X.; Tanaka, L.; Wolin, S. L.; Elkon, K. B.; Kawasumi, M.

Cell Death, Nucleic Acids, and Immunity Inflammation Beyond the Grave

ARTHRITIS & RHEUMATOLOGY

IF10.9

2018-04-18

OAAI

Elkon, Keith B.

TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2017-06-12

OAAI

Lood, Christian; Arve, Sabine; Ledbetter, Jeffrey; Elkon, Keith B.

Ultraviolet B Irradiation Causes Stimulator of Interferon Genes-Dependent Production of Protective Type I Interferon in Mouse Skin by Recruited Inflammatory Monocytes

ARTHRITIS & RHEUMATOLOGY

IF10.9

2017-03-29

OAAI

Sontheimer, Clayton; Liggitt, Denny; Elkon, Keith B.

Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus

ARTHRITIS & RHEUMATOLOGY

IF10.9

2017-03-07

155

OAAI

An, Jie; Durcan, Laura; Karr, Reynold M.; Briggs, Tracy A.; Rice, Gillian I.; Teal, Thomas H.; Woodward, Joshua J.; Elkon, Keith B.

Antimalarial Drugs as Immune Modulators: New Mechanisms for Old Drugs

ANNUAL REVIEW OF MEDICINE

IF0

2017-01-14

104

OAAI

An, Jie; Minie, Mark; Sasaki, Tomikazu; Woodward, Joshua J.; Elkon, Keith B.

Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus

ARTHRITIS & RHEUMATOLOGY

IF10.9

2016-12-02

OAAI

An, Jie; Briggs, Tracy A.; Dumax-Vorzet, Audrey; Alarcon-Riquelme, Marta E.; Belot, Alexandre; Beresford, Michael; Bruce, Ian N.; Carvalho, Claudia; Chaperot, Laurence; Frostegard, Johan; Plumas, Joel; Rice, Gillian I.; Vyse, Timothy J.; Wiedeman, Alice; Crow, Yanick J.; Elkon, Keith B.

Blood-Borne RNA Correlates with Disease Activity and IFN-Stimulated Gene Expression in Systemic Lupus Erythematosus

JOURNAL OF IMMUNOLOGY

IF3.4

2016-10-01

OAAI

Doedens, John R.; Jones, Wendell D.; Hill, Kay; Mason, Michael J.; Gersuk, Vivian H.; Mease, Philip J.; Dall'Era, Maria; Aranow, Cynthia; Martin, Richard W.; Cohen, Stanley B.; Fleischmann, Roy M.; Kivitz, Alan J.; Burge, Daniel J.; Chaussabel, Damien; Elkon, Keith B.; Posada, James A.

研究方向