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D

Daniel D. Brown

department of pharmacology
H指数:15
被引数:724

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Targeting HDAC and proteostasis to eradicate quiescent cancer cells

靶向HDAC和蛋白质稳态以清除休眠癌细胞

Cancer Gene Therapy
IF5
2026-08-130
OA
Qi Jiang; Michelle Ertel; Austin Arrigo; Amjad Hijazzi; Sara Sannino; Jennifer L. Goeckeler-Fried; April Sagan; Ian Beddows; Betsy Ann Varghese; Daniel D. Brown; Wayne Stallaert; Adrian Lee; Amanda M. Clark; Hui Shen; Jeffrey L. Brodsky; Hatice U. Osmanbeyoglu; Ronald J. Buckanovich
A dependency map enhanced with next-generation 3D cancer models

一张融合了新一代3D癌症模型的药物靶点互作图

Nature
IF48.5
2026-08-050
OA
James V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez
Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women
Nature Aging
IF19.4
2026-07-270
OA
Neil Carleton; Alexander Chih-Chieh Chang; Sanghoon Lee; Ruxuan Li; Jian Zou; Daniel D. Brown; Jagmohan Hooda; Jian Chen; Rahul Kumar; Linda R. Klei; Lora H. Rigatti; Joseph Newsome; Dixcy Jaba Sheeba John Mary; Jennifer M. Atkinson; Raymond E. West; Thomas D. Nolin; Patrick J. Oberly; Ziyu Huang; Donald Poirier; Emilia J. Diego; Peter C. Lucas; George C. Tseng; Michael T. Lotze; Priscilla F. McAuliffe; Ioannis K. Zervantonakis; Steffi Oesterreich; Adrian V. Lee
Identification of the MRTFA/SRF pathway as a critical regulator of quiescence and chemotherapy resistance in cancer.

鉴定MRTFA/SRF通路为癌症中休眠和化疗耐药的关键调节因子。

Cancer Letters
IF10.1
2026-03-120
PRE
Santiago Panesso-Gómez; Alexander J. Cole; Austin Arrigo; Alex Roberts; Maya Bello; Alyssa Wield; Vivian I. Anyaeche; Stacy McGonigal; Amjad Hijazi; Jaynish Shah; Qi Jiang; Tonge Ebai; Allison C. Sharrow; George Tseng; Euisik Yoon; Daniel D. Brown; Amanda M. Clark; Scott D. Larsen; Ian Eder; David Gau
Integrating artificial intelligence-driven digital pathology and genomics to establish patient-derived organoids as new approach methodologies for drug response in head and neck cancer

整合人工智能驱动的数字病理学和基因组学，以建立基于患者来源的类器官作为头颈癌药物反应的新方法学。

Oral Oncology
IF3.9
2025-11-090
OAAI
Rose Doerfler; Jie Chen; Carl Kim; Joshua D. Smith; Micah Harris; Krishna B. Singh; Brian Isett; Rebekah E. Dadey; Daniel D. Brown; Adrian V. Lee; Xuefeng Wang; Matthew E. Spector; Seungwon Kim; Shaum Sridharan; Kevin Contrera; Katelyn Smith; Carly Reeder; Maureen Lyons; Jianhua Luo; Silvia Liu; Dan P. Zandberg; Heath D. Skinner; Ioannis K. Zervantonakis; Lazar Vujanović; Robert L. Ferris; Raja R. Seethala; José P. Zevallos; Jason J. Luke; Riyue Bao
p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2+ breast cancer that limits trastuzumab deruxtecan efficacy

p95HER2，HER2癌蛋白的一种截断形式，在HER2+乳腺癌中驱动一种免疫抑制程序，限制了T-DXd（trastuzumab deruxtecan）的疗效。

Nature Cancer
IF28.5
2025-06-270
PRE
Dong Hu; Xiaoshuang Lyu; Zheqi Li; Prasanna Ekambaram; Anushka Dongre; Tanner Freeman; Marion Joy; Jennifer M. Atkinson; Daniel D. Brown; Zongyou Cai; Neil M. Carleton; Hannah E. Crentsil; John Little; Felicia Kemp; Linda R. Klei; Maria Beecher; Jeff Sperinde; Weidong Huang; Heikki Joensuu; Ashok Srinivasan; Katherine L. Pogue-Geile; Ying Wang; Huichen Feng; Lisa D. Eli; Alshad S. Lalani; Jian Zou; George C. Tseng; Tullia C. Bruno; Adrian V. Lee; Steffi Oesterreich; Norman Wolmark; Carmen J. Allegra; Samuel A. Jacobs; Linda M. McAllister-Lucas; Peter C. Lucas
Hope for OTHERS - An organ donation program for metastatic breast cancer research
CANCER RESEARCH
IF16.6
2023-03-010
PRE
Oesterreich, Steffi; Miller, Lori; Rosenzweig, Margaret Q.; Bartholow, Tanner L.; Yates, Megan; Elangovan, Ashuvinee; Savariau, Laura; Casey, Allison N.; Priedigkeit, Nolan; Ding, Kai; Wedn, Abdalla; Bin Liu, Jie; Brown, Daniel D.; Hyder, Tara; Pecar, Geoffrey; Carleton, Neil; Bittar, Humberto Trejo; Geisler, Daniel; Lopez-Nunez, Oscar; Clark, Amanda M.; Wells, Alan; Roy, Partha; Puhalla, Shannon; Howard, Naomi; Needles, Christine; Trent, Susan; Walker, Stephanie; Hodgdon, Christine; Bhargava, Rohit; Atkinson, Jennifer M.; Lee, Adrian V.
ER alpha-positive human cell line xenograft models recapitulate metastatic dissemination and endocrine response of invasive lobular breast carcinoma
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Tasdemir, Nilgun; Savariau, Laura; Scott, Julie; Latoche, Joseph D.; Hou, Weizhou; Biery, Kyle; Chung, Minji; Bossart, Emily A.; Sreekumar, Sreeja; Brown, Daniel D.; Nasrazadani, Azadeh; Qin, Ye; Hooda, Jagmohan; Chen, Fangyuan; Castro, Carlos A.; Anderson, Carolyn J.; Atkinson, Jennifer; Lucas, Peter C.; Davison, Nancy E.; Lee, Adrian, V; Oesterreich, Steffi

研究方向

暂未获取到该数据
A
Adrian V. Lee
H 指数:85论文数:1,045被引数:2.6万
S
Steffi Oesterreich
H 指数:63论文数:897被引数:1.6万
J
Jennifer M. Atkinson
H 指数:27论文数:199被引数:2,586
P
Priscilla F. McAuliffe
H 指数:27论文数:190被引数:2,910
J
Jagmohan Hooda
H 指数:12论文数:79被引数:702
P
Peter C. Lucas
H 指数:55论文数:434被引数:1.4万
G
George C. Tseng
H 指数:64论文数:613被引数:1.3万
M
Megan E. Yates
H 指数:10论文数:133被引数:351
S
Steffi Oesterreich
H 指数:7论文数:44被引数:356
I
Ioannis K. Zervantonakis
H 指数:31论文数:185被引数:5,210