He N. Xu - Publications, H-index & Citations

He N. Xu

University of Pennsylvania

21H指数

104论文数

1.7K被引数

收录论文 32

发表时间

Distinct Mitochondrial Recovery Dynamics Following Taxol Removal in Triple-Negative Breast Cancer Cells 三阴性乳腺癌细胞在紫杉醇去除后的不同线粒体恢复动力学

Cells

IF5.2

2026-09-26

OAAI

Jack Kollmar; Mihiar Wannousse; Julia Tchou; Lin Z. Li; He N. Xu

Live-Cell Optical Redox Imaging Reveals Metabolic Heterogeneity and Context-Dependent Responses to Metabolic Perturbation in TNBC Cells 活细胞光学还原成像揭示三阴性乳腺癌细胞中代谢异质性和对代谢扰动的依赖性反应

Metabolites

IF3.7

2026-08-30

OAAI

He N. Xu; Jack Kollmar; Allison Podsednik; Mihiar Wannousse; Alexander Shestov; Roddy S. O’Connor; Joseph A. Baur; Julia Tchou; Rong Zhou; Lin Z. Li

β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer Β-羟基丁酸酯增强癌症中CAR T细胞的代谢适应性

Cell

IF42.5

2026-03-06

PREAI

Shan Liu; Puneeth Guruprasad; Ranjani Ramasubramanian; Bhoomi Madhu; Luca Paruzzo; Kecheng Han; Andre Kelly; Alexander Shestov; He N. Xu; Alberto Carturan; Chaoting Zhou; Kevin R. Amses; Amichay Afriat; Lev Litichevskiy; Jason Lin; Ezra Dubowitz; Neil Tangal; Jing Zhang; Alana McSween; Melody Tan

Bibliometrics and potential gene analysis of post-translational modifications in lung cancer 文献计量学及肺癌中翻译后修饰的潜在基因分析

Journal of Thoracic Disease

IF1.9

2025-12-31

PREAI

Xu, He; Ma, Yao

Optical Redox Imaging of Breast Cancer NADH Redox Status Associated with PGC1α Gene Expression 乳腺癌NADH氧化还原状态的光学氧化还原成像及其与PGC1α基因表达的关系

Academic Radiology

IF3.9

2025-12-18

OAAI

Zhenwu Lin; Yu Wen; He N. Xu; Lijun Zhang; Chenbo Zeng; Tony R. Lin; Joanna Floros; Robert Mach; Lin Z. Li

Differential Mitochondrial Redox Responses to the Inhibition of NAD+ Salvage Pathway of Triple Negative Breast Cancer Cells 三阴性乳腺癌细胞中，抑制NAD+补救途径引起的差异线粒体氧化还原反应

CANCERS

IF4.4

2024-12-24

OAAI

Kollmar, Jack; Xu, Junmei; Gonzalves, Diego; Baur, Joseph A.; Li, Lin Z.; Tchou, Julia; Xu, He N.

Use of Optical Redox Imaging to Quantify Alveolar Macrophage Redox State in Infants: Proof of Concept Experiments in a Murine Model and Human Tracheal Aspirates Samples (vol 13, 546, 2024)

ANTIOXIDANTS

IF6.6

2024-10-18

OAAI

Xu, He N.; Gonzalves, Diego; Hoffman, Jonathan H.; Baur, Joseph A.; Li, Lin Z.; Jensen, Erik A.

MRG002-HER2 ADC combined with pucotenlimab (a PD-1 inhibitor), in patients with locally advanced or metastatic urothelial carcinoma (UC): Preliminary results of a phase I/II study MRG002-HER2 ADC与pucotenlimab（一种PD-1抑制剂）联合治疗局部晚期或转移性尿路上皮癌（UC）患者的I/II期研究初步结果

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Cui, C.; Zhou, L.; Yang, Y.; Qu, W.; Sheng, X.; Chi, Z.; Si, L.; Mao, L.; Lian, B.; Wang, X.; Yan, X.; Li, S.; Li, C.; Wei, X.; Li, J.; Duan, R.; Xu, H.; Zhou, A.; Guo, J.

Disitamab vedotin (DV) plus toripalimab (T) in unresectable locally advanced or metastatic urothelial carcinoma (la/mUC): Long-term outcomes from a phase Ib/II study Disitamab vedotin (DV) 联合 toripalimab (T) 治疗不可切除局部晚期或转移性尿路上皮癌 (la/mUC) 的长期疗效：一项 Ib/II 期研究的结果

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Zhou, L.; Yang, K.; Zhang, S.; Yan, X.; Li, S.; Xu, H.; Li, J.; Chi, Z.; Mao, L.; Lian, B.; Bixia, T.; Wang, X.; Guo, H.; He, Z.; Guo, J.; Sheng, X.

Use of Optical Redox Imaging to Quantify Alveolar Macrophage Redox State in Infants: Proof of Concept Experiments in a Murine Model and Human Tracheal Aspirates Samples

ANTIOXIDANTS

IF6.6

2024-04-29

OAAI

Xu, He N.; Gonzalves, Diego; Hoffman, Jonathan H.; Baur, Joseph A.; Li, Lin Z.; Jensen, Erik A.

TAK-500 is a clinical stage immune-cell directed antibody drug conjugate (iADC) inducing STING activation in CCR2-expressing intratumor myeloid cells and favorable immunomodulation TAK-500是一种临床阶段的免疫细胞定向抗体药物偶联物 (iADC)，可诱导CCR2-expressing肿瘤内髓样细胞的STING激活和良好的免疫调节

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Schalper, Kurt A.; Matsuda, Atsushi; Ganno-Sherwood, Michelle; Maldonado-Lopez, Angel E.; Rosentrater, Emily; Porciuncula, Angelo; Zhang, Dong Mei; Christensen, Camilla L.; Merrigan, Samantha A.; Hatten, Tiquella; Lee, Hong Myung; Lee, Min Young; Dong, Linlin; Huang, Jian; Iartchouk, Natasha; Wang, Jianing; Xu, He; Yoneyama, Tomoki; Piatkov, Konstantin I.; Harbison, Carole E.; Parent, Alex; Lineberry, Neil; Abu-Yousif, Adnan O.; Appleman, Vicky

Development of an Endoscopic Auto-Fluorescent Sensing Device to Aid in the Detection of Breast Cancer and Inform Photodynamic Therapy

METABOLITES

IF3.7

2022-11-11

OAAI

Gaitan, Brandon; Inglut, Collin; Kanniyappan, Udayakumar; Xu, He N.; Conant, Emily F.; Frankle, Lucas; Li, Lin Z.; Chen, Yu; Huang, Huang-Chiao

Optical Redox Imaging of Ex Vivo Hippocampal Tissue Reveals Age-Dependent Alterations in the 5XFAD Mouse Model of Alzheimer's Disease

METABOLITES

IF3.7

2022-08-25

OAAI

Xu, He N.; Gourmaud, Sarah; Podsednik, Allison; Li, Xiaofan; Zhao, Huaqing; Jensen, Frances E.; Talos, Delia M.; Li, Lin Z.

Subcellular analysis of nuclear and cytoplasmic redox indices differentiates breast cancer cell subtypes better than nuclear-to-cytoplasmic area ratio

JOURNAL OF BIOMEDICAL OPTICS

IF2.9

2022-08-01

OAAI

Jacob, Annemarie; Xu, He N.; Stout, Andrea L.; Li, Lin Z.

Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-05-17

OAAI

Vyskocil, Stepan; Cardin, David; Ciavarri, Jeffrey; Conlon, Joe; Cullis, Courtney; England, Dylan; Gershman, Rachel; Gigstad, Kenneth; Gipson, Krista; Gould, Alexandra; Greenspan, Paul; Griffin, Robert; Gulavita, Nanda; Harrison, Sean; Hu, Zhigen; Hu, Yongbo; Hata, Akito; Huang, Jian; Huang, Shih-Chung; Janowick, Dave; Jones, Matthew; Kolev, Vihren; Langston, Steven P.; Lee, Hong Myung; Li, Gang; Lok, David; Ma, Liting; Mai, Doanh; Malley, Jenna; Matsuda, Atsushi; Mizutani, Hirotake; Mizutani, Miho; Molchanova, Nina; Nunes, Elise; Pusalkar, Sandeep; Renou, Christelle; Rowland, Scott; Sato, Yosuke; Shaw, Michael; Shen, Luhua; Shi, Zhan; Skene, Robert; Soucy, Francois; Stroud, Steve; Xu, He; Xu, Tianlin; Abu-Yousif, Adnan O.; Zhang, Ji

Dimethyl Fumarate, an Approved Multiple Sclerosis Treatment, Reduces Brain Oxidative Stress in SIV-Infected Rhesus Macaques: Potential Therapeutic Repurposing for HIV Neuroprotection

ANTIOXIDANTS

IF6.6

2021-03-09

OAAI

Garcia-Mesa, Yoelvis; Xu, He N.; Vance, Patricia; Gruenewald, Analise L.; Garza, Rolando; Midkiff, Cecily; Alvarez-Hernandez, Xavier; Irwin, David J.; Gill, Alexander J.; Kolson, Dennis L.

Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-02-25

113

OAAI

Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil; Bowman, Douglas; Bump, Nancy; Chau, Ryan; Chuang, Bei-Ching; Claiborne, Christopher; Cohen, Larry; Connolly, Kelly; Duffey, Matthew; Durvasula, Nitya; Freeze, Scott; Gallery, Melissa; Galvin, Katherine; Gaulin, Jeffrey; Gershman, Rachel; Greenspan, Paul; Grieves, Jessica; Guo, Jianping; Gulavita, Nanda; Hailu, Shumet; He, Xingyue; Hoar, Kara; Hu, Yongbo; Hu, Zhigen; Ito, Mitsuhiro; Kim, Mi-Sook; Lane, Scott Weston; Lok, David; Lublinsky, Anya; Mallender, William; McIntyre, Charles; Minissale, James; Mizutani, Hirotake; Mizutani, Miho; Molchinova, Nina; Ono, Koji; Patil, Ashok; Qian, Mark; Riceberg, Jessica; Shindi, Vaishali; Sintchak, Michael D.; Song, Keli; Soucy, Teresa; Wang, Yana; Xu, He; Yang, Xiaofeng; Zawadzka, Agatha; Zhang, Ji; Pulukuri, Sai M.

Sex and SP-A2 Dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19

ANTIOXIDANTS

IF6.6

2020-09-25

OAAI

Xu, He N.; Lin, Zhenwu; Gandhi, Chintan K.; Amatya, Shaili; Wang, Yunhua; Li, Lin Z.; Floros, Joanna

Commemorating Britton Chance

MOLECULAR IMAGING AND BIOLOGY

IF2.5

2019-04-24

OAAI

Li, Lin Z.; Xu, He N.; Yodh, Arjun G.