未登录 Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation 自身免疫病风险基因ANKRD55通过代谢调控促进TH17效应功能 Xu, Jinjin; Kong, Lingjia; Creasey, Elizabeth A.; Rath, Sneha; Deng, Lei; Avila-Pacheco, Julian; Li, Chenhao; Oliver, Blayne A.; Dao, Tyler T.; Shih, Angela R.; Daly, Mark J.; Shalek, Alex K.; Clish, Clary B.; Graham, Daniel B.; Deguine, Jacques; Xavier, Ramnik J. 分享 收藏
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A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells 一种表达MHCII和ror γ t的独特人类细胞类型，具有树突状细胞和3型固有淋巴样细胞的双重特征 Antonova, Alina Ulezko; Lonardi, Silvia; Monti, Matilde; Missale, Francesco; Fan, Changxu; Coates, Matthew L.; Bugatti, Mattia; Jaeger, Natalia; Rodrigues, Patrick Fernandes; Brioschi, Simone; Trsan, Tihana; Fachi, Jose L.; Nguyen, Khai M.; Nunley, Ryan M.; Moratto, Daniele; Zini, Stefania; Kong, Lingjia; Deguine, Jacques; Peeples, Mark E.; Xavier, Ramnik J.; Clatworthy, Menna R.; Wang, Ting; Cella, Marina; Vermi, William; Colonna, Marco 分享 收藏
The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon (vol 56, pg 444, 2023) Kong, Lingjia; Pokatayev, Vladislav; Lefkovith, Ariel; Carter, Grace T.; Creasey, Elizabeth A.; Krishna, Chirag; Subramanian, Sathish; Kochar, Bharati; Ashenberg, Orr; Lau, Helena; Ananthakrishnan, Ashwin N.; Graham, Daniel B.; Deguine, Jacques; Xavier, Ramnik J. 分享 收藏
Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production Xu, Jinjin; Kong, Lingjia; Oliver, Blayne A.; Li, Bihua; Creasey, Elizabeth A.; Guzman, Gaelen; Schenone, Monica; Carey, Kimberly L.; Carr, Steven A.; Graham, Daniel B.; Deguine, Jacques; Xavier, Ramnik J. 分享 收藏
The landscape of immune dysregulation in Crohn?s disease revealed through single-cell transcriptomic profiling in the ileum and colon 通过回肠和结肠中的单细胞转录组分析揭示了克罗恩病的免疫失调景观 Kong, Lingjia; Pokatayev, Vladislav; Lefkovith, Ariel; Carter, Grace T.; Creasey, Elizabeth A.; Krishna, Chirag; Subramanian, Sathish; Kochar, Bharati; Ashenberg, Orr; Lau, Helena; Ananthakrishnan, Ashwin N.; Graham, Daniel B.; Deguine, Jacques; Xavier, Ramnik J. 分享 收藏
Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults Chou, Chih-Hung; Mohanty, Subhasis; Kang, Heather A.; Kong, Lingjia; Avila-Pacheco, Julian; Joshi, Samit R.; Ueda, Ikuyo; Devine, Lesley; Raddassi, Khadir; Pierce, Kerry; Jeanfavre, Sarah; Bullock, Kevin; Meng, Hailong; Clish, Clary; Santori, Fabio R.; Shaw, Albert C.; Xavier, Ramnik J. 分享 收藏
Long Intergenic Noncoding RNA MIAT as a Regulator of Human Th17 Cell Differentiation 长基因间非编码RNA MIAT作为人类Th17细胞分化的调节剂 Khan, Mohd Moin; Khan, Meraj Hasan; Kalim, Ubaid Ullah; Khan, Sofia; Junttila, Sini; Paulin, Niklas; Kong, Lingjia; Rasool, Omid; Elo, Laura L.; Lahesmaa, Riitta 分享 收藏
Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes Kong, Lingjia; Moorlag, Simone J. C. F. M.; Lefkovith, Ariel; Li, Bihua; Matzaraki, Vasiliki; Emst, Liesbeth van; Kang, Heather A.; Latorre, Isabel; Jaeger, Martin; Joosten, Leo A. B.; Netea, Mihai G.; Xavier, Ramnik J. 分享 收藏
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TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41 Carey, Kimberly L.; Paulus, Geraldine L. C.; Wang, Lingfei; Balce, Dale R.; Luo, Jessica W.; Bergman, Phil; Ferder, Ianina C.; Kong, Lingjia; Renaud, Nicole; Singh, Shantanu; Kost-Alimova, Maria; Nyfeler, Beat; Lassen, Kara G.; Virgin, Herbert W.; Xavier, Ramnik J. 分享 收藏
The synthesized transporter K16APoE enabled the therapeutic HAYED peptide to cross the blood-brain barrier and remove excess iron and radicals in the brain, thus easing Alzheimer's disease 合成的转运蛋白K16APoE使治疗性HAYED肽能够穿过血脑屏障并去除大脑中多余的铁和自由基，从而缓解阿尔茨海默氏病 Zou, Zhenyou; Shen, Qiqiong; Pang, Yanxia; Li, Xin; Chen, Yongfeng; Wang, Xinjuan; Luo, Xinhua; Wu, Zhongmin; Bao, Zhaosheng; Zhang, Juanli; Liang, Jiawei; Kong, Lingjia; Yan, Lunan; Xiong, Lijun; Zhu, Tianjun; Yuan, Shuaibin; Wang, Miaoyang; Cai, Kewei; Yao, Yinning; Wu, Jianchao; Jiang, Yuding; Liu, Heng; Liu, Jing; Zhou, Yan; Dong, Qianqian; Wang, Wei; Zhu, Kangjie; Li, Li; Lou, Yingjie; Wang, Hongdian; Li, Yizi; Lin, Hong 分享 收藏
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Characterization of candidate genes in inflammatory bowel disease-associated risk loci Peloquin, Joanna M.; Goel, Gautam; Kong, Lingjia; Huang, Hailiang; Haritunians, Talin; Sartor, R. Balfour; Daly, Mark J.; Newberry, Rodney D.; McGovern, Dermot P.; Yajnik, Vijay; Lira, Sergio A.; Xavier, Ramnik J. 分享 收藏
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Toll-like Receptor 5 in Obesity: The Role of Gut Microbiota and Adipose Tissue Inflammation Pekkala, Satu; Munukka, Eveliina; Kong, Lingjia; Pollanen, Eija; Autio, Reija; Roos, Christophe; Wiklund, Petri; Fischer-Posovszky, Pamela; Wabitsch, Martin; Alen, Markku; Huovinen, Pentti; Cheng, Sulin 分享 收藏
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