未登录 Optimization of VE607 to generate analogs with improved neutralization activities against SARS-CoV-2 variants VE607优化以生成对SARS-CoV-2变体具有增强中和活性的类似物 Ding, Shilei; Yang, Derek; Ullah, Irfan; Niu, Ling; Unger, Matthew; Diaz-Salinas, Marco A.; Chandravanshi, Monika; Zhou, Fei; Beaudoin-Bussieres, Guillaume; Benlarbi, Mehdi; Tolbert, William D.; Yoon, Keon-Woong; Xu, Ruixue; Laroche, Genevieve; Gaudette, Fleur; Morton, Abraham J.; Lang, Zabrina C.; Son, Anna; Abrams, Cameron; Cote, Marceline; Smith III, Amos B.; Huang, Rick K.; Matthies, Doreen; Munro, James B.; Pazgier, Marzena; Uchil, Pradeep D.; Finzi, Andres 分享 收藏
The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation 保守的HIV-1间隔肽2触发基质晶格成熟 Stacey, James C. V.; Hrebik, Dominik; Nand, Elizabeth; Shetty, Snehith Dyavari; Qu, Kun; Boicu, Marius; Anders-oesswein, Maria; Uchil, Pradeep D.; Dick, Robert A.; Mothes, Walther; Kraeusslich, Hans-Georg; Mueller, Barbara; Briggs, John A. G. 分享 收藏
TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF-κB-Responsive Long Terminal Repeat Elements( vol 85 , pg 5183 , 2011) Kajaste-Rudnitski, Anna; Marelli, Sara S.; Pultrone, Cinzia; Pertel, Thomas; Uchil, Pradeep D.; Mechti, Nadir; Mothes, Walther; Poli, Guido; Luban, Jeremy; Vicenzi, Elisa 分享 收藏
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Proof- of- concept studies with a computationally designed Mpro inhibitor as a synergistic combination regimen alternative to Paxlovid Papini, Christina; Ullah, Irfan; Ranjan, Amalendu P.; Zhang, Shuo; Wu, Qihao; Spasov, Krasimir A.; Zhang, Chunhui; Mothes, Walther; Crawford, Jason M.; Lindenbach, Brett D.; Uchil, Pradeep D.; Kumar, Priti; Jorgensen, William L.; Anderson, Karen S. 分享 收藏
Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine 基于OMV的SARS-CoV-2疫苗的免疫原性和临床前功效 Grandi, Alberto; Tomasi, Michele; Ullah, Irfan; Bertelli, Cinzia; Vanzo, Teresa; Accordini, Silvia; Gagliardi, Assunta; Zanella, Ilaria; Benedet, Mattia; Corbellari, Riccardo; Di Lascio, Gabriele; Tamburini, Silvia; Caproni, Elena; Croia, Lorenzo; Rava, Micol; Fumagalli, Valeria; Di Lucia, Pietro; Marotta, Davide; Sala, Eleonora; Iannacone, Matteo; Kumar, Priti; Mothes, Walther; Uchil, Pradeep D.; Cherepanov, Peter; Bolognesi, Martino; Pizzato, Massimo; Grandi, Guido 分享 收藏
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry Leonhardt, Susan A.; Purdy, Michael D.; Grover, Jonathan R.; Yang, Ziwei; Poulos, Sandra; McIntire, William E.; Tatham, Elizabeth A.; Erramilli, Satchal K.; Nosol, Kamil; Lai, Kin Kui; Ding, Shilei; Lu, Maolin; Uchil, Pradeep D.; Finzi, Andres; Rein, Alan; Kossiakoff, Anthony A.; Mothes, Walther; Yeager, Mark 分享 收藏
Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models Lorenzo, Maria M.; Marin-Lopez, Alejandro; Chiem, Kevin; Jimenez-Cabello, Luis; Ullah, Irfan; Utrilla-Trigo, Sergio; Calvo-Pinilla, Eva; Lorenzo, Gema; Moreno, Sandra; Ye, Chengjin; Park, Jun-Gyu; Matia, Alejandro; Brun, Alejandro; Sanchez-Puig, Juana M.; Nogales, Aitor; Mothes, Walther; Uchil, Pradeep D.; Kumar, Priti; Ortego, Javier; Fikrig, Erol; Martinez-Sobrido, Luis; Blasco, Rafael 分享 收藏
The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice Ullah, Irfan; Beaudoin-Bussieres, Guillaume; Symmes, Kelly; Cloutier, Marc; Ducas, Eric; Tauzin, Alexandra; Laumaea, Annemarie; Grunst, Michael W.; Dionne, Katrina; Richard, Jonathan; Begin, Philippe; Mothes, Walther; Kumar, Priti; Bazin, Renee; Finzi, Andres; Uchil, Pradeep D. 分享 收藏
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities 工程ACE2-Fc通过直接中和和Fc效应子活性对抗小鼠致死性SARS-CoV-2感染 Chen, Yaozong; Sun, Lulu; Ullah, Irfan; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Hederman, Andrew P.; Tolbert, William D.; Sherburn, Rebekah; Nguyen, Dung N.; Marchitto, Lorie; Ding, Shilei; Wu, Di; Luo, Yuhong; Gottumukkala, Suneetha; Moran, Sean; Kumar, Priti; Piszczek, Grzegorz; Mothes, Walther; Ackerman, Margaret E.; Finzi, Andres; Uchil, Pradeep D.; Gonzalez, Frank J.; Pazgier, Marzena 分享 收藏
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A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection Fc增强的NTD结合非中和抗体延迟病毒扩散，并与nAb协同保护小鼠免受致死性SARS-CoV-2感染 Beaudoin-Bussieres, Guillaume; Chen, Yaozong; Ullah, Irfan; Prevost, Jeremie; Tolbert, William D.; Symmes, Kelly; Ding, Shilei; Benlarbi, Mehdi; Gong, Shang Yu; Tauzin, Alexandra; Gasser, Romain; Chatterjee, Debashree; Vezina, Dani; Goyette, Guillaume; Richard, Jonathan; Zhou, Fei; Stamatatos, Leonidas; McGuire, Andrew T.; Charest, Hughes; Roger, Michel; Pozharski, Edwin; Kumar, Priti; Mothes, Walther; Uchil, Pradeep D.; Pazgier, Marzena; Finzi, Andres 分享 收藏
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern 两种广泛中和抗体针对SARS-CoV-2令人关注的新兴变体的结构基础和作用方式 Li, Wenwe; Chen, Yaozong; Prevost, Jeemie; Ullah, Irfan; Lu, Maoli; Gong, Shang Yu; Tauzin, Alexandra; Gasser, Romain; Vezina, Dani; Anand, Sai Priya; Goyette, Guillaume; Chaterjee, Debashree; Ding, Shilei; Tolbert, William D.; Grunst, Michael W.; Bo, Yuxia; Zhang, Shijian; Richard, Jonathan; Zhou, Fei; Huang, Rick K.; Esser, Lothar; Zeher, Allison; Cote, Marceline; Kumar, Priti; Sodroski, Joseph; Xia, Di; Uchil, Pradeep D.; Pazgier, Marzena; Finzi, Andres; Mothes, Walther 分享 收藏
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy 小鼠SARS-CoV-2感染的实时成像显示，中和抗体需要Fc功能才能获得最佳疗效 Ullah, Irfan; Prevost, Jeremie; Ladinsky, Mark S.; Stone, Helen; Lu, Maolin; Anand, Sai Priya; Beaudoin-Bussieres, Guillaume; Symmes, Kelly; Benlarbi, Mehdi; Ding, Shilei; Gasser, Romain; Fink, Corby; Chen, Yaozong; Tauzin, Alexandra; Goyette, Guillaume; Bourassa, Catherine; Medjahed, Halima; Mack, Matthias; Chung, Kunho; Wilen, Craig B.; Dekaban, Gregory A.; Dikeakos, Jimmy D.; Bruce, Emily A.; Kaufmann, Daniel E.; Stamatatos, Leonidas; McGuire, Andrew T.; Richard, Jonathan; Pazgier, Marzena; Bjorkman, Pamela J.; Mothes, Walther; Finzi, Andres; Kumar, Priti; Uchil, Pradeep D. 分享 收藏
In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission Haugh, Kelsey A.; Ladinsky, Mark S.; Ullah, Irfan; Stone, Helen M.; Pi, Ruoxi; Gilardet, Alexandre; Grunst, Michael W.; Kumar, Priti; Bjorkman, Pamela J.; Mothes, Walther; Uchil, Pradeep D. 分享 收藏
Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice Ventura, John D.; Beloor, Jagadish; Allen, Edward; Zhang, Tongyu; Haugh, Kelsey A.; Uchil, Pradeep D.; Ochsenbauer, Christina; Kieffer, Collin; Kumar, Priti; Hope, Thomas J.; Mothes, Walther 分享 收藏
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