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Prospective observational study to assess the feasibility and safety of appropriate Plasmodium vivax radical cure with tafenoquine or primaquine after quantitative G6PD testing during pilot implementation in Thailand 前瞻性观察性研究，旨在评估在泰国试点实施期间，在定量G6PD检测后，使用阿托喹酮或伯氨喹进行适当的间日疟原虫根治的可行性与安全性。 Sudathip, Prayuth; Khantikul, Nardlada; Saejeng, Aungkana; Duparc, Stephan; Daumerie, Penny Grewal; Lynch, Caroline; Jambert, Elodie; Viboonsanti, Saowanee; Areechokchai, Darin; Kanjanasuwan, Jerdsuda; Thong-ard, Thannika; Kowsurat, Panupong; Borghini-Fuhrer, Isabelle; Padungtod, Chantana 分享 收藏
Operational effectiveness of tafenoquine and primaquine for the prevention of Plasmodium vivax recurrence in Brazil: a retrospective observational study Brito, Marcelo; Rufatto, Rosilene; Brito-Sousa, Jose Diego; Murta, Felipe; Sampaio, Vanderson; Balieiro, Patricia; Baia-Silva, Djane; Castro, Vanessa; Alves, Brenda; Alencar, Aline; Duparc, Stephan; Daumerie, Penny Grewal; Borghini-Fuhrer, Isabelle; Jambert, Elodie; Peterka, Cassio; Lima Jr, Francisco Edilson; Maia, Leonardo Carvalho; Cruz, Catherine Lucena; Maciele, Bruna; Vasconcelos, Mariana; Machado, Myrna; Figueira, Elder Augusto; Balieiro, Antonio Alcirley; Pereira, Dhelio Batista; Lacerda, Marcus 分享 收藏
Tafenoquine co-administered with dihydroartemisinin- piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study Sutanto, Inge; Soebandrio, Amin; Ekawati, Lenny L.; Chand, Krisin; Noviyanti, Rintis; Satyagraha, Ari Winasti; Subekti, Decy; Santy, Yulia Widya; Crenna-Darusallam, Chelzie; Instiaty, Instiaty; Budiman, Waras; Prasetya, Catur Bidik; Lardo, Soroy; Elyazar, Iqbal; Duparc, Stephan; Cedar, Eve; Rolfe, Katie; Fernando, Disala; Berni, Alessandro; Jones, Sion; Kleim, Joerg-Peter; Fletcher, Kim; Sharma, Hema; Martin, Ana; Taylor, Maxine; Goyal, Navin; Green, Justin A.; Tan, Lionel K.; Baird, J. Kevin 分享 收藏
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial Chandiwana, Nomathemba; Kruger, Chelsea; Johnstone, Hilary; Chughlay, Mohamed Farouk; Ju, Chung; Kim, Byungsu; Dineka, Yengiwe; Arbe-Barnes, Sarah; Miller, Robert; Owen, Andrew; Hill, Andrew; Windgassen, Daniel; Abla, Nada; Marrast, Anne Claire; Duparc, Stephan; Venter, Willem Daniel Francois 分享 收藏
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Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data Mansoor, Rashid; Commons, Robert J.; Douglas, Nicholas M.; Abuaku, Benjamin; Achan, Jane; Adam, Ishag; Adjei, George O.; Adjuik, Martin; Alemayehu, Bereket H.; Allan, Richard; Allen, Elizabeth N.; Anvikar, Anupkumar R.; Arinaitwe, Emmanuel; Ashley, Elizabeth A.; Ashurst, Hazel; Asih, Puji B. S.; Bakyaita, Nathan; Barennes, Hubert; Barnes, Karen, I; Basco, Leonardo; Bassat, Quique; Baudin, Elisabeth; Bell, David J.; Bethell, Delia; Bjorkman, Anders; Boulton, Caroline; Bousema, Teun; Brasseur, Philippe; Bukirwa, Hasifa; Burrow, Rebekah; Carrara, Verena, I; Cot, Michel; D'Alessandro, Umberto; Das, Debashish; Das, Sabyasachi; Davis, Timothy M. E.; Desai, Meghna; Djimde, Abdoulaye A.; Dondorp, Arjen M.; Dorsey, Grant; Drakeley, Chris J.; Duparc, Stephan; Espie, Emmanuelle; Etard, Jean-Francois; Falade, Catherine; Faucher, Jean Francois; Filler, Scott; Fogg, Carole; Fukuda, Mark; Gaye, Oumar; Genton, Blaise; Rahim, Awab Ghulam; Gilayeneh, Julius; Gonzalez, Raquel; Grais, Rebecca F.; Grandesso, Francesco; Greenwood, Brian; Grivoyannis, Anastasia; Hatz, Christoph; Hodel, Eva Maria; Humphreys, Georgina S.; Hwang, Jimee; Ishengoma, Deus; Juma, Elizabeth; Kachur, S. Patrick; Kager, Piet A.; Kamugisha, Erasmus; Kamya, Moses R.; Karema, Corine; Kayentao, Kassoum; Kazienga, Adama; Kiechel, Jean-Rene; Kofoed, Poul-Erik; Koram, Kwadwo; Kremsner, Peter G.; Lalloo, David G.; Laman, Moses; Lee, Sue J.; Lell, Bertrand; Maiga, Amelia W.; Martensson, Andreas; Mayxay, Mayfong; Mbacham, Wilfred; McGready, Rose; Menan, Herve; Menard, Didier; Mockenhaupt, Frank; Moore, Brioni R.; Muller, Olaf; Nahum, Alain; Ndiaye, Jean-Louis; Newton, Paul N.; Ngasala, Billy E.; Nikiema, Frederic; Nji, Akindeh M.; Noedl, Harald; Nosten, Francois; Ogutu, Bernhards R.; Ojurongbe, Olusola; Osorio, Lyda; Ouedraogo, Jean-Bosco; Owusu-Agyei, Seth; Pareek, Anil; Penali, Louis K.; Piola, Patrice; Plucinski, Mateusz; Premji, Zul; Ramharter, Michael; Richmond, Caitlin L.; Rombo, Lars; Rosenthal, Philip J.; Salman, Sam; Same-Ekobo, Albert; Sibley, Carol; Sirima, Sodiomon B.; Smithuis, Frank M.; Some, Fabrice A.; Staedke, Sarah G.; Starzengruber, Peter; Strub-Wourgaft, Nathalie; Sutanto, Inge; Swarthout, Todd D.; Syafruddin, Din; Talisuna, Ambrose O.; Taylor, Walter R.; Temu, Emmanuel A.; Thwing, Julie, I; Tinto, Halidou; Tjitra, Emiliana; Toure, Offianan A.; Tran, T. Hien; Ursing, Johan; Valea, Innocent; Valentini, Giovanni; van Vugt, Michele; von Seidlein, Lorenz; Ward, Stephen A.; Were, Vincent; White, Nicholas J.; Woodrow, Charles J.; Yavo, William; Yeka, Adoke; Zongo, Issaka; Simpson, Julie A.; Guerin, Philippe J.; Stepniewska, Kasia; Price, Ric N.; Roper, Cally 分享 收藏
Tafenoquine exposure assessment, safety, and relapse prevention efficacy in children with Plasmodium vivax malaria: open-label, single-arm, non-comparative, multicentre, pharmacokinetic bridging, phase 2 trial Velez, Ivan D.; Hien, Tran T.; Green, Justin A.; Martin, Ana; Sharma, Hema; Rousell, Victoria M.; Breton, John J.; Ernest, Terry B.; Rolfe, Katie; Taylor, Maxine; Mohamed, Khadeeja; Jones, Sion W.; Chau, Nguyen Hoang; Hoa, Nhu Thi; Duparc, Stephan; Tan, Lionel K.; Goyal, Navin 分享 收藏
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study Lutete, Gaston Tona; Mombo-Ngoma, Ghyslain; Assi, Serge-Brice; Bigoga, Jude D.; Koukouikila-Koussounda, Felix; Ntamabyaliro, Nsengi Y.; Ntoumi, Francine; Agnandji, Selidji T.; Groger, Mirjam; Shin, Jangsik; Borghini-Fuhrer, Isabelle; Arbe-Barnes, Sarah; Allen, Stephen J.; Kremsner, Peter G.; Miller, Robert; Duparc, Stephan; Ramharter, Michael 分享 收藏
Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial 吡那啶-青蒿琥酯在无症状疟疾感染者中的疗效，安全性和耐受性: 一项随机对照试验 Dabira, Edgard D.; Hachizovu, Sebastian; Conteh, Bakary; Mendy, Alieu; Nyang, Haddy; Lawal, Bolarinde; Ndiath, Mamadou Ousmane; Mulenga, Joyce M.; Mwanza, Sydney; Borghini-Fuhrer, Isabelle; Arbe-Barnes, Sarah; Miller, Robert; Shin, Jangsik; Duparc, Stephan; D'Alessandro, Umberto; Manyando, Christine; Achan, Jane 分享 收藏
Safety, Tolerability, Pharmacokinetics, and Antimalarial Activity of the Novel Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 in Healthy Volunteers Sinxadi, Phumla; Donini, Cristina; Johnstone, Hilary; Langdon, Grant; Wiesner, Lubbe; Allen, Elizabeth; Duparc, Stephan; Chalon, Stephan; McCarthy, James S.; Lorch, Ulrike; Chibale, Kelly; Moehrle, Joerg; Barnes, Karen, I 分享 收藏
Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data Chan, Xin Hui S.; Win, Yan Naung; Haeusler, Ilsa L.; Tan, Jireh Y.; Loganathan, Shanghavie; Saralamba, Sompob; Chan, Shu Kiat S.; Ashley, Elizabeth A.; Barnes, Karen I.; Baiden, Rita; Bassi, Peter U.; Djimde, Abdoulaye; Dorsey, Grant; Duparc, Stephan; Hanboonkunupakarn, Borimas; ter Kuile, Feiko O.; Lacerda, Marcus V. G.; Nasa, Amit; Nosten, Franc Comma Ois H.; Onyeji, Cyprian O.; Pukrittayakamee, Sasithon; Siqueira, Andre M.; Tarning, Joel; Taylor, Walter R. J.; Valentini, Giovanni; van Vugt, Michele; Wesche, David; Day, Nicholas P. J.; Huang, Christopher L-H; Brugada, Josep; Price, Ric N.; White, Nicholas J. 分享 收藏
Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers Ackert, Jessica; Mohamed, Khadeeja; Slakter, Jason S.; El-Harazi, Sherif; Berni, Alessandro; Gevorkyan, Hakop; Hardaker, Elizabeth; Hussaini, Azra; Jones, Sion W.; Koh, Gavin C. K. W.; Patel, Jyoti; Rasmussen, Scott; Kelly, Deborah S.; Baranano, David E.; Thompson, John T.; Warren, Keith A.; Sergott, Robert C.; Tonkyn, John; Wolstenholme, Allen; Coleman, Hanna; Yuan, Alex; Duparc, Stephan; Green, Justin A. 分享 收藏
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method Funck-Brentano, Christian; Ouologuem, Nouhoum; Duparc, Stephan; Felices, Mathieu; Sirima, Sodiomon B.; Sagara, Issaka; Soulama, Issiaka; Ouedraogo, Jean-Bosco; Beavogui, Abdoul H.; Borghini-Fuhrer, Isabelle; Khan, Yasmin; Djimde, Abdoulaye A.; Voiriot, Pascal 分享 收藏
Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation Funck-Brentano, Christian; Bacchieri, Antonella; Valentini, Giovanni; Pace, Silvia; Tommasini, Silva; Voiriot, Pascal; Ubben, David; Duparc, Stephan; Evene, Eric; Felices, Mathieu; Corsi, Marco 分享 收藏
Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria Lacerda, M. V. G.; Llanos-Cuentas, A.; Krudsood, S.; Lon, C.; Saunders, D. L.; Mohammed, R.; Yilma, D.; Batista Pereira, D.; Espino, F. E. J.; Mia, R. Z.; Chuquiyauri, R.; Val, F.; Casapia, M.; Monteiro, W. M.; Brito, M. A. M.; Costa, M. R. F.; Buathong, N.; Noedl, H.; Diro, E.; Getie, S.; Wubie, K. M.; Abdissa, A.; Zeynudin, A.; Abebe, C.; Tada, M. S.; Brand, F.; Beck, H. -P.; Angus, B.; Duparc, S.; Kleim, J. -P.; Kellam, L. M.; Rousell, V. M.; Jones, S. W.; Hardaker, E.; Mohamed, K.; Clover, D. D.; Fletcher, K.; Breton, J. J.; Ugwuegbulam, C. O.; Green, J. A.; Koh, G. C. K. W. 分享 收藏
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria Llanos-Cuentas, A.; Lacerda, M. V. G.; Hien, T. T.; Velez, I. D.; Namaik-Iarp, C.; Chu, C. S.; Villegas, M. F.; Val, F.; Monteiro, W. M.; Brito, M. A. M.; Costa, M. R. F.; Chuquiyauri, R.; Casapia, M.; Nguyen, C. H.; Aruachan, S.; Papwijitsil, R.; Nosten, F. H.; Bancone, G.; Angus, B.; Duparc, S.; Craig, G.; Rousell, V. M.; Jones, S. W.; Hardaker, E.; Clover, D. D.; Kendall, L.; Mohamed, K.; Koh, G. C. K. W.; Wilches, V. M.; Breton, J. J.; Green, J. A. 分享 收藏
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Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study 单剂量DSM265，一种新型疟原虫二氢乳清酸脱氢酶抑制剂，在无并发症的恶性疟原虫或间日疟原虫感染患者中的抗疟活性: 概念验证，开放标签，2a期研究 Llanos-Cuentas, Alejandro; Casapia, Martin; Chuquiyauri, Raul; Hinojosa, Juan-Carlos; Kerr, Nicola; Rosario, Maria; Toovey, Stephen; Arch, Robert H.; Phillips, Margaret A.; Rozenberg, Felix D.; Bath, Jade; Ng, Caroline L.; Cowell, Annie N.; Winzeler, Elizabeth A.; Fidock, David A.; Baker, Mark; Mohrle, Jorg J.; van Huijsduijnen, Rob Hooft; Gobeau, Nathalie; Araeipour, Nada; Andenmatten, Nicole; Ruckle, Thomas; Duparc, Stephan 分享 收藏
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