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L

Lalitha R. Belur

University of Minnesota Twin Cities

H指数:18

被引数:1,358

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Generation and characterization of an immunodeficient mouse model of mucopolysaccharidosis type II

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-04-012

OAAI

Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine

MOLECULAR THERAPY

IF12

2023-04-014

OAAI

Comparative effectiveness of intravenous and intrathecal AAV9. CB7.hIDS (RGX-121) in a murine model of mucopolysaccharidosis type II

MOLECULAR GENETICS AND METABOLISM

IF3.5

2022-02-010

PRE

Treatment of cardiac, neurologic, and skeletal manifestations of murine MPS I with AAV9-IDUA: Efficacy study of vector dose and route of administration

MOLECULAR GENETICS AND METABOLISM

IF3.5

2022-02-010

PRE

Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2021-05-1034

OAAI

Comparative systemic and neurologic effectiveness of intravenous and intrathecal AAV9 delivered individually or combined in a murine model mucopolysaccharidosis type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2021-02-011

PREAI

Ex vivo lentiviral transduction of hematopoietic stem cells in mucopolysaccharidosis type II (MPS II) mice achieves high levels of systemic iduronate-2-sulfatase (IDS) enzyme activity and normalization of glycosaminoglycans (GAGs)

MOLECULAR GENETICS AND METABOLISM

IF3.5

2021-02-010

PREAI

Effect of supraphysiological alpha-L-iduronidase (IDUA) expression on skeletal manifestations in mucopolysaccharidosis type I (MPS I) mice following ex vivo lentiviral vector transduction of hematopoietic stem cells

MOLECULAR GENETICS AND METABOLISM

IF3.5

2021-02-010

PREAI

Systemic high-level IDUA enzyme activity with correction of neurologic deficit in mucopolysaccharidosis type I mice by ex vivo lentiviral transduction of hematopoietic stem cells

MOLECULAR GENETICS AND METABOLISM

IF3.5

2020-02-010

PREAI

Recovery of neurologic function in mucopolysaccharidosis type I mice with existing neurocognitive dysfunction by treatment with AAV9-IDUA vector

MOLECULAR GENETICS AND METABOLISM

IF3.5

2017-01-010

PREAI

Relative effectiveness of different routes of AAV administration for gene therapy of mucopolysaccharidosis

MOLECULAR GENETICS AND METABOLISM

IF3.5

2017-01-010

PREAI

Intranasal Gene Delivery of AAV Iduronidase: An Effective and Non-Invasive Approach for Treatmentof CNS Disease in a Murine Model of MPS Type I

MOLECULAR THERAPY

IF12

2016-05-010

OAAI

Therapeutic Effectiveness of AAV-Mediated Iduronidase Delivery to the CNS Following Intravenous Administration in a Murine Model of Mucopolysaccharidosis Type I

MOLECULAR THERAPY

IF12

2016-05-010

OAAI

Gene delivery and biodistribution following intravenous administration of AAV9/rh10 iduronidase in a murine model of MPS type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2016-02-010

PREAI

Intranasal gene delivery of AAV9 iduronidase: A non-invasive and effective gene therapy approach for prevention of neurologic disease in a murine model of mucopolysaccharidosis type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2016-02-010

PREAI

Non-Invasive Intranasal Administration of AAV9-Iduronidase Prevents Emergence of Neurologic Disease and Neurocognitive Dysfunction in a Murine Model of Mucopolysaccharidosis Type I

MOLECULAR THERAPY

IF12

2015-05-010

OAAI

Intrathecal and intranasal infusion of adeno-associated virus vector: non-invasive routes of administration achieving corrective levels of iduronidase expression throughout the brain for gene therapy of mucopolysaccharidosis type I

MOLECULAR GENETICS AND METABOLISM

IF3.5

2014-02-010

PREAI

Comparison of Endovascular and Intraventricular Gene Therapy With Adeno-Associated Virus-α-L-Iduronidase for Hurler Disease

IF3.9

2014-01-0125

OAAI

PR_b functionalized stealth liposomes for targeted delivery to metastatic colon cancer

BIOMATERIALS SCIENCE

IF5.7

2013-01-0119

PRE

Direct gene transfer to the CNS prevents emergence of neurologic disease in a murine model of mucopolysaccharidosis type I

直接基因转移至CNS可防止I型粘多糖贮积症小鼠模型中神经系统疾病的出现

NEUROBIOLOGY OF DISEASE

IF5.6

2011-07-0183

OAAI