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J

Jonathan Rios-Doria

AstraZeneca
H指数:15
被引数:1,320

个人简介

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教育背景

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荣誉奖项

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INCA33890, a novel PD-1xTGF.R2 bispecific antibody conditionally antagonizes TGFβ signaling in primary immune cells co- expressing PD-
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Wang, Liang-Chuan S.; Klooster, Rinse; Kulkarni, Ashwini; de Vinuesa, Amaya Garcia; Soloviev, Maxim; Hendriks, Linda J. A.; Huo, Lu; Weber, Michael; Mondal, Arpita; Zhao, Yonghong; Harvey, Shane; He, Xin; Chang, Hong; Horsey, April; Volgina, Alla; Zhang, Yue; Pandey, Veethika; Yang, Yan-Ou; Rios-Doria, Jonathan; Eruslanov, Evgeniy; Powell, Daniel J.; Albelda, Steven M.; de Kruif, John; Nastri, Horacio; Geuijen, Cecile; Mayes, Patrick A.
Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
CANCER DISCOVERY
IF33.3
2022-03-0768
OAAI
Koblish, Holly K.; Wu, Liangxing; Wang, Liang-Chuan S.; Liu, Phillip C. C.; Wynn, Richard; Rios-Doria, Jonathan; Spitz, Susan; Liu, Hao; Volgina, Alla; Zolotarjova, Nina; Kapilashrami, Kanishk; Behshad, Elham; Covington, Maryanne; Yang, Yan-Ou; Li, Jingwei; Diamond, Sharon; Soloviev, Maxim; O'Hayer, Kevin; Rubin, Stephen; Kanellopoulou, Chrysi; Yang, Gengjie; Rupar, Mark; DiMatteo, Darlise; Lin, Luping; Stevens, Christina; Zhang, Yue; Thekkat, Pramod; Geschwindt, Ryan; Marando, Cindy; Yeleswaram, Swamy; Jackson, Jeff; Scherle, Peggy; Huber, Reid; Yao, Wenqing; Hollis, Gregory
A Potent and Selective Dual Inhibitor of AXL and MERTK Possesses Both Immunomodulatory and Tumor-Targeted Activity
FRONTIERS IN ONCOLOGY
IF3.3
2020-12-0734
OAAI
Rios-Doria, Jonathan; Favata, Margaret; Lasky, Kerri; Feldman, Patricia; Lo, Yvonne; Yang, Gengjie; Stevens, Christina; Wen, Xiaoming; Sehra, Sarita; Katiyar, Kamna; Liu, Ke; Wynn, Richard; Harris, Jennifer J.; Ye, Min; Spitz, Susan; Wang, Xiaozhao; He, Chunhong; Li, Yun-Long; Yao, Wenqing; Covington, Maryanne; Scherle, Peggy; Koblish, Holly
Characterization of INCB081776, a potent and selective dual AXL/MER kinase inhibitor
CANCER RESEARCH
IF16.6
2018-07-0112
PRE
Favata, Margaret; Lasky, Kerri; Lo, Yvonne; Feldman, Patricia; Li, Jun; Chen, Yaoyu; Stevens, Christina; Ye, Min; Wang, Hui; Liu, Ke; Wynn, Richard; Li, Yanlong; Harris, Jennifer; Landman, Robert; Li, Yu; Wang, Xiaozhao; He, Chunhong; Li, Yun-Long; Xue, Chu-Biao; Yao, Wenqing; Rios-Doria, Jonathan; Gao, Zhenhai; Covington, Maryanne; Liu, Xuesong M.; Koblish, Holly; Scherle, Peggy
Antibody-drug conjugates bearing pyrrolobenzodiazepine or tubulysin payloads alter the tumor immune microenvironment and synergize with multiple immunotherapies
CANCER RESEARCH
IF16.6
2017-07-011
PRE
Rios-Doria, Jonathan; Harper, Jay; Rothstein, Raymond; Wetzel, Leslie; Chesebrough, Jon; Marrero, Allison; Chen, Cui; Strout, Patrick; Mulgrew, Kathy; McGlinchey, Kelly; Fleming, Ryan; Bezabeh, Binyam; Meekin, John; Stewart, David; Kennedy, Maureen; Martin, Philip; Buchanan, Andrew; Dimasi, Nazzareno; Michelotti, Emil; Hollingsworth, Robert
Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies

带有吡咯并苯并二氮杂或微管溶素有效载荷的抗体-药物结合物具有免疫调节作用，并与多种免疫疗法协同作用

CANCER RESEARCH
IF16.6
2017-05-1484
OAAI
Rios-Doria, Jonathan; Harper, Jay; Rothstein, Raymond; Wetzel, Leslie; Chesebrough, Jon; Marrero, Allison; Chen, Cui; Strout, Patrick; Mulgrew, Kathy; McGlinchey, Kelly; Fleming, Ryan; Bezabeh, Binyam; Meekin, John; Stewart, David; Kennedy, Maureen; Martin, Philip; Buchanan, Andrew; Dimasi, Nazzareno; Michelotti, Emil; Hollingsworth, Robert
Targeting CD73 in the tumor microenvironment with MEDI9447
ONCOIMMUNOLOGY
IF6.3
2016-07-11247
OAAI
Hay, Carl M.; Sult, Erin; Huang, Qihui; Mulgrew, Kathy; Fuhrmann, Stacy R.; McGlinchey, Kelly A.; Hammond, Scott A.; Rothstein, Raymond; Rios-Doria, Jonathan; Poon, Edmund; Holoweckyj, Nick; Durham, Nicholas M.; Leow, Ching Ching; Diedrich, Gundo; Damschroder, Melissa; Herbst, Ronald; Hollingsworth, Robert E.; Sachsenmeier, Kris F.
Medi3622, a monoclonal antibody to ADAM17, inhibits tumor growth by inhibiting EGFR- and non-EGFR-mediated pathways
CANCER RESEARCH
IF16.6
2015-08-010
PRE
Sabol, Darrin; RiosDoria, Jonathan; Chesebrough, Jon; Stewart, David; Schifferli, Kevin; Rothstein, Raymond; Leow, Ching Ching; Heidbrink-Thompson, Jenny; Cheng, Li; Du, Qun; Xu, Linda; Jin, Xiaofang; Tammali, Ravinder; Gao, Chanshou; Friedman, Jay; Wilkinson, Brandy; Damschroder, Melissa; Pierce, Andrew; Patnaik, MunMun; Zeng, Rong; Wu, Yuling; Spitz, Susan; Robbie, Gabriel; Roskos, Lorin; Hollingsworth, Robert; Tice, David; Michelotti, Emil
A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways
MOLECULAR CANCER THERAPEUTICS
IF5.5
2015-07-0647
OAAI
Rios-Doria, Jonathan; Sabol, Darrin; Chesebrough, Jon; Stewart, Dave; Xu, Linda; Tammali, Ravinder; Cheng, Li; Du, Qun; Schifferli, Kevin; Rothstein, Ray; Leow, Ching Ching; Heidbrink-Thompson, Jenny; Jin, Xiaofang; Gao, Changshou; Friedman, Jay; Wilkinson, Brandy; Damschroder, Melissa; Pierce, Andrew J.; Hollingsworth, Robert E.; Tice, David A.; Michelotti, Emil F.

研究方向

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H
Holly K. Koblish
H 指数:26论文数:115被引数:4,111
R
Robert E. Hollingsworth
H 指数:36论文数:253被引数:4,913
C
Christina Stevens
H 指数:13论文数:123被引数:748
R
Raymond Rothstein
H 指数:17论文数:110被引数:1,957
L
Leslie Wetzel
H 指数:10论文数:50被引数:1,035
J
Jon Chesebrough
H 指数:8论文数:38被引数:618
K
Kerri Lasky
H 指数:6论文数:40被引数:267
W
Wenqing Yao
H 指数:31论文数:138被引数:3,590
E
Emil F. Michelotti
H 指数:14论文数:47被引数:1,647
C
Ching Ching Leow
H 指数:22论文数:155被引数:2,625