未登录 Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA YOLK) administered by parenteral or mucosal routes against Brucella ovis in rams 评价聚丙烯抗原BLSOmp31与新型笼状颗粒佐剂(ISPA YOLK)结合后，通过皮内或黏膜途径给药对绵羊布鲁氏菌Brucella ovis的疗效评估 Moran, Maria Celeste; Santos, Agostina Tammone; Dominguez, Paula; Moriones, Lucila; Farias, Maria Victoria Nieto; Mate, Laura; Garcia, Juan Agustin; Kuhn, Tobias; Paolicchi, Fernando Alberto; Fiorentino, Maria Andrea; Rodriguez, Marcelo Gaston; Garcia, Jorge Pablo; Cacciato, Claudio Santiago; Goldbaum, Fernando Alberto; Zylberman, Vanesa; Pardo, Romina Paola; Foscaldi, Sabrina; Lutzelschwab, Claudia Maria; Lupi, Giuliana; Marcipar, Ivan Santiago; Estein, Silvia Marcela 分享 收藏
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome 工程化志贺毒素基免疫原的冷冻电镜结构，这些免疫原能够诱导具有治疗潜力的中和抗体，以对抗溶血性尿毒症综合征 Cristofalo, Alejandro Ezequiel; Sharma, Arvind; Cerutti, Maria Laura; Sharma, Kedar; Melero, Roberto; Pardo, Romina; Goldbaum, Fernando Alberto; Borgnia, Mario; Zylberman, Vanesa; Otero, Lisandro Horacio 分享 收藏
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A phase I study to evaluate the safety, tolerance and pharmacokinetics of anti-Shiga toxin hyperimmune equine F (ab′)2 fragments in healthy volunteers Hiriart, Yanina; Scibona, Paula; Ferraris, Augusto; Belloso, Waldo H.; Beruto, Valeria; Bournissen, Facundo Garcia; Zylberman, Vanesa; Munoz, Luciana; Goldbaum, Fernando; Spatz, Linus; Colonna, Mariana; Sanguineti, Santiago; Simonovich, Ventura A. 分享 收藏
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A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers Llauger, Gabriela; Melero, Roberto; Monti, Demian; Sycz, Gabriela; Huck-Iriart, Cristian; Cerutti, Maria L.; Klinke, Sebastian; Mikkelsen, Evelyn; Tijman, Ariel; Arranz, Rocio; Alfonso, Victoria; Arellano, Sofia M.; Goldbaum, Fernando A.; Sterckx, Yann G. J.; Carazo, Jose-Maria; Kaufman, Sergio B.; Dans, Pablo D.; del Vas, Mariana; Otero, Lisandro H. 分享 收藏
Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms Srinivasan, Lakshmi; Alzogaray, Vanina; Selvakumar, Dakshnamurthy; Nathan, Sara; Yoder, Jesse B.; Wright, Katharine M.; Klinke, Sebastian; Nwafor, Justin N.; Labanda, Maria S.; Goldbaum, Fernando A.; Schon, Arne; Freire, Ernesto; Tomaselli, Gordon F.; Amzel, L. Mario; Ben-Johny, Manu; Gabelli, Sandra B. 分享 收藏
Non-clinical safety assessment and in vivo biodistribution of CoviFab, an RBD-specific F(ab')2 fragment derived from equine polyclonal antibodies Salinas, Facundo; Marelli, Belkis E. E.; Sanguineti, Santiago; Goldbaum, Fernando; Munoz, Luciana; Etchevers, Lucas; Silvestrini, Paula; Notaro, Ulises S. S.; Salvetti, Natalia R. R.; Zylberman, Vanesa; Ortega, Hugo H. H. 分享 收藏
Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level Otero, Lisandro H.; Foscaldi, Sabrina; Antelo, Giuliano T.; Rosano, German L.; Sirigu, Serena; Klinke, Sebastian; Defelipe, Lucas A.; Sanchez-Lamas, Maximiliano; Battocchio, Giovanni; Conforte, Valeria; Vojnov, Adrian A.; Chavas, Leonard M. G.; Goldbaum, Fernando A.; Mroginski, Maria-Andrea; Rinaldi, Jimena; Bonomi, Hernan R. 分享 收藏
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Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms Conforte, Valeria; Horacio Otero, Lisandro; Toum, Laila; Sirigu, Serena; Tomas Antelo, Giuliano; Rinaldi, Jimena; Foscaldi, Sabrina; Klinke, Sebastian; Chavas, Leonard Michel Gabriel; Alberto Vojnov, Adrian; Alberto Goldbaum, Fernando; Malamud, Florencia; Ruy Bonomi, Hernan 分享 收藏
Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase Rinaldi, Jimena; Fernandez, Ignacio; Shin, Heewhan; Sycz, Gabriela; Gunawardana, Semini; Kumarapperuma, Indika; Paz, Juan M.; Otero, Lisandro H.; Cerutti, Maria L.; Zorreguieta, Angeles; Ren, Zhong; Klinke, Sebastian; Yang, Xiaojing; Goldbaum, Fernando A. 分享 收藏
RBD-specific polyclonal F(ab′)2 fragments of equine antibodies in patients with moderate to severe COVID-19 disease: A randomized, multicenter, double-blind, placebo-controlled, adaptive phase 2/3 clinical trial Lopardo, Gustavo; Belloso, Waldo H.; Nannini, Esteban; Colonna, Mariana; Sanguineti, Santiago; Zylberman, Vanesa; Munoz, Luciana; Dobarro, Martin; Lebersztein, Gabriel; Farina, Javier; Vidiella, Gabriela; Bertetti, Anselmo; Crudo, Favio; Fernanda Alzogaray, Maria; Barcelona, Laura; Teijeiro, Ricardo; Lambert, Sandra; Scublinsky, Dario; Iacono, Marisa; Stanek, Vanina; Solari, Ruben; Cruz, Pablo; Martin Casas, Marcelo; Abusamra, Lorena; Lucas Luciardi, Hector; Cremona, Alberto; Caruso, Diego; de Miguel, Bernardo; Perez Lloret, Santiago; Millan, Susana; Kilstein, Yael; Pereiro, Ana; Sued, Omar; Cahn, Pedro; Spatz, Linus; Goldbaum, Fernando 分享 收藏
Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59 Pellizza, Leonardo; Lopez, Jose L.; Vazquez, Susana; Sycz, Gabriela; Guimaraes, Beatriz G.; Rinaldi, Jimena; Goldbaum, Fernando A.; Aran, Martin; Mac Cormack, Walter P.; Klinke, Sebastian 分享 收藏
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Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein 通过嵌合蛋白引发的抗MICA抗体恢复抗肿瘤免疫力 Torres, Nicolas; Victoria Regge, Maria; Secchiari, Florencia; David Friedrich, Adrian; German Spallanzani, Raul; Raffo Iraolagoitia, Ximena Lucia; Yanel Nunez, Sol; Mariel Sierra, Jessica; Ziblat, Andrea; Cecilia Santilli, Maria; Gilio, Nicolas; Almada, Evangelina; Lauche, Constanza; Pardo, Romina; Ines Domaica, Carolina; Beatriz Fuertes, Mercedes; Patrick Madauss, Kevin; Hance, Kenneth W.; Gloger, Israel S.; Zylberman, Vanesa; Alberto Goldbaum, Fernando; Walter Zwirner, Norberto 分享 收藏
Development and Evaluation of a Novel VHH-Based Immunocapture Assay for High-Sensitivity Detection of Shiga Toxin Type 2 (Stx2) in Stool Samples Melli, Luciano J.; Zylberman, Vanesa; Hiriart, Yanina; Lauche, Constanza E.; Baschkier, Ariela; Pardo, Romina; Miliwebsky, Elizabeth; Chinen, Isabel; Rivas, Marta; Goldbaum, Fernando A.; Ugalde, Juan E.; Comerci, Diego J.; Ciocchini, Andres E. 分享 收藏
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Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+tumors in mouse models in vivo Fumey, William; Koenigsdorf, Julia; Kunick, Valentin; Menzel, Stephan; Schuetze, Kerstin; Unger, Mandy; Schriewer, Levin; Haag, Friedrich; Adam, Gerhard; Oberle, Anna; Binder, Mascha; Fliegert, Ralf; Guse, Andreas; Zhao, Yong Juan; Lee, Hon Cheung; Malavasi, Fabio; Goldbaum, Fernando; van Hegelsom, Rob; Stortelers, Catelijne; Bannas, Peter; Koch-Nolte, Friedrich 分享 收藏
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