Peter J. Facchini - Publications, H-index & Citations

Peter J. Facchini

University of Calgary

64H指数

259论文数

1.2W被引数

收录论文 110

发表时间

Bioproduction of a Large-Scale Library of Tryptamine Derivatives for Neuropsychiatric Drug Screening 大规模色胺衍生物库的生物合成及其在精神神经药物筛选中的应用

ACS CHEMICAL BIOLOGY

IF3.8

2025-05-15

PREAI

Hagel, JM; Chang, LM; Li, J; Chen, X; Yu, LS; Gallant, JA; Facchini, PJ

Two ubiquitous aldo-keto reductases in the genus Papaver support a patchwork model for morphine pathway evolution

COMMUNICATIONS BIOLOGY

IF5.1

2024-10-29

OAAI

Carr, Samuel C.; Rehman, Fasih; Hagel, Jillian M.; Chen, Xue; Ng, Kenneth K. S.; Facchini, Peter J.

Novel Psilocin Prodrugs with Altered Pharmacological Properties as Candidate Therapies for Treatment-Resistant Anxiety Disorders

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-11-20

OAAI

Raithatha, Sheetal A.; Hagel, Jillian M.; Matinkhoo, Kaveh; Yu, Lisa; Press, David; Cook, Sarah G.; Sharma, Govinda; Dhananjaya, D.; Jensen, Glynnis; Lee, Jessica B.; Cai, Charlie; Gallant, Jonathan; Bains, Jaideep; Tucker, Joseph E.; Facchini, Peter J.

A cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic amines

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-10-01

OAAI

Chen, Xue; Li, Jing; Yu, Lisa; Maule, Francesca; Chang, Limei; Gallant, Jonathan A.; Press, David J.; Raithatha, Sheetal A.; Hagel, Jillian M.; Facchini, Peter J.

Elucidation of the mescaline biosynthetic pathway in peyote (Lophophora williamsii)

PLANT JOURNAL

IF5.7

2023-09-07

OAAI

Watkins, Jacinta L.; Li, Qiushi; Yeaman, Sam; Facchini, Peter J.

Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera)

SCIENTIFIC REPORTS

IF3.9

2023-02-20

OAAI

Menendez-Perdomo, Ivette M. M.; Facchini, Peter J. J.

Strong Feedback Inhibition of Key Enzymes in the Morphine Biosynthetic Pathway from Opium Poppy Detectable in Engineered Yeast

ACS CHEMICAL BIOLOGY

IF3.8

2023-02-03

PREAI

Ozber, Natali; Yu, Lisa; Hagel, Jillian M.; Facchini, Peter J.

Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation

NATURE COMMUNICATIONS

IF15.7

2022-11-09

OAAI

Ozber, Natali; Carr, Samuel C.; Morris, Jeremy S.; Liang, Siyu; Watkins, Jacinta L.; Caldo, Kristian M.; Hagel, Jillian M.; Ng, Kenneth K. S.; Facchini, Peter J.

Phloem-specific localization of benzylisoquinoline alkaloid metabolism in opium poppy

JOURNAL OF PLANT PHYSIOLOGY

IF4.1

2022-04-01

PREAI

Ozber, Natali; Facchini, Peter J.

Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-10-01

OAAI

Carr, Samuel C.; Torres, Megan A.; Morris, Jeremy S.; Facchini, Peter J.; Ng, Kenneth K. S.

Crystal Structure of Codeinone Reductase Reveals Novel Features Responsible for Defining Benzylisoquinoline Alkaloid Substrate Specificity

FASEB JOURNAL

IF4.2

2021-05-14

OAAI

Carr, Samuel; Morris, Jeremy; Torres, Megan; Facchini, Peter; Ng, Kenneth

Back to the plant: overcoming roadblocks to the microbial production of pharmaceutically important plant natural products

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

IF3.2

2020-10-01

OAAI

Ozber, Natali; Watkins, Jacinta L.; Facchini, Peter J.

Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy (vol 11, 1190, 2020)

NATURE COMMUNICATIONS

IF15.7

2020-06-04

OAAI

Li, Qiushi; Ramasamy, Sukanya; Singh, Pooja; Hagel, Jillian M.; Dunemann, Sonja M.; Chen, Xue; Chen, Rongji; Yu, Lisa; Tucker, Joseph E.; Facchini, Peter J.; Yeaman, Sam

Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy 罂粟生物碱代谢途径的基因聚类和拷贝数变异

NATURE COMMUNICATIONS

IF15.7

2020-03-04

OAAI

Li, Qiushi; Ramasamy, Sukanya; Singh, Pooja; Hagel, Jillian M.; Dunemann, Sonja M.; Chen, Xue; Chen, Rongji; Yu, Lisa; Tucker, Joseph E.; Facchini, Peter J.; Yeaman, Sam

A single residue determines substrate preference in benzylisoquinoline alkaloid N-methyltransferases

PHYTOCHEMISTRY

IF3.4

2020-02-01

PREAI

Morris, Jeremy S.; Yu, Lisa; Facchini, Peter J.

Isolation and characterization of two O-methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in sacred lotus (Nelumbo nucifera)神圣莲花 (Nelumbo nucifera) 中参与苄基异喹啉生物碱生物合成的两个O-甲基转移酶的隔离和表征

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-02-01

OAAI

Menendez-Perdomo, Ivette M.; Facchini, Peter J.