未登录Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging
Honda, Keiko; Takahashi, Hiroo; Hata, Saori; Abe, Ruriko; Saito, Takashi; Saido, Takaomi C.; Taru, Hidenori; Sobu, Yuriko; Ando, Kanae; Yamamoto, Tohru; Suzuki, Toshiharu .png)
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收藏Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment大规模动物模型研究发现大脑pH和乳酸水平的改变是涉及认知障碍的神经精神障碍的诊断内表型Hagihara, Hideo; Shoji, Hirotaka; Hattori, Satoko; Sala, Giovanni; Takamiya, Yoshihiro; Tanaka, Mika; Ihara, Masafumi; Shibutani, Mihiro; Hatada, Izuho; Hori, Kei; Hoshino, Mikio; Nakao, Akito; Mori, Yasuo; Okabe, Shigeo; Matsushita, Masayuki; Urbach, Anja; Katayama, Yuta; Matsumoto, Akinobu; Nakayama, Keiichi I.; Katori, Shota; Sato, Takuya; Iwasato, Takuji; Nakamura, Haruko; Goshima, Yoshio; Raveau, Matthieu; Tatsukawa, Tetsuya; Yamakawa, Kazuhiro; Takahashi, Noriko; Kasai, Haruo; Inazawa, Johji; Nobuhisa, Ikuo; Kagawa, Tetsushi; Taga, Tetsuya; Darwish, Mohamed; Nishizono, Hirofumi; Takao, Keizo; Sapkota, Kiran; Nakazawa, Kazutoshi; Takagi, Tsuyoshi; Fujisawa, Haruki; Sugimura, Yoshihisa; Yamanishi, Kyosuke; Rajagopal, Lakshmi; Hannah, Nanette Deneen; Meltzer, Herbert Y.; Yamamoto, Tohru; Wakatsuki, Shuji; Araki, Toshiyuki; Tabuchi, Katsuhiko; Numakawa, Tadahiro; Kunugi, Hiroshi; Huang, Freesia L.; Hayata-Takano, Atsuko; Hashimoto, Hitoshi; Tamada, Kota; Takumi, Toru; Kasahara, Takaoki; Kato, Tadafumi; Graef, Isabella A.; Crabtree, Gerald R.; Asaoka, Nozomi; Hatakama, Hikari; Kaneko, Shuji; Kohno, Takao; Hattori, Mitsuharu; Hoshiba, Yoshio; Miyake, Ryuhei; Obi-Nagata, Kisho; Hayashi-Takagi, Akiko; Becker, Lea J.; Yalcin, Ipek; Hagino, Yoko; Kotajima-Murakami, Hiroko; Moriya, Yuki; Ikeda, Kazutaka; Kim, Hyopil; Kaang, Bong-Kiun; Otabi, Hikari; Yoshida, Yuta; Toyoda, Atsushi; Komiyama, Noboru H.; Grant, Seth G. N.; Ida-Eto, Michiru; Narita, Masaaki; Matsumoto, Ken-Ichi; Okuda-Ashitaka, Emiko; Ohmori, Iori; Shimada, Tadayuki; Yamagata, Kanato; Ageta, Hiroshi; Tsuchida, Kunihiro; Inokuchi, Kaoru; Sassa, Takayuki; Kihara, Akio; Fukasawa, Motoaki; Usuda, Nobuteru; Katano, Tayo; Tanaka, Teruyuki; Yoshihara, Yoshihiro; Igarashi, Michihiro; Hayashi, Takashi; Ishikawa, Kaori; Yamamoto, Satoshi; Nishimura, Naoya; Nakada, Kazuto; Hirotsune, Shinji; Egawa, Kiyoshi; Higashisaka, Kazuma; Tsutsumi, Yasuo; Nishihara, Shoko; Sugo, Noriyuki; Yagi, Takeshi; Ueno, Naoto; Yamamoto, Tomomi; Kubo, Yoshihiro; Ohashi, Rie; Shiina, Nobuyuki; Shimizu, Kimiko; Higo-Yamamoto, Sayaka; Oishi, Katsutaka; Mori, Hisashi; Furuse, Tamio; Tamura, Masaru; Shirakawa, Hisashi; Sato, Daiki X.; Inoue, Yukiko U.; Inoue, Takayoshi; Komine, Yuriko; Yamamori, Tetsuo; Sakimura, Kenji; Miyakawa, Tsuyoshi 分享 收藏 Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1Shiraki, Yuzuha; Mitsuma, Monet; Takada, Ritsuko; Hata, Saori; Kitamura, Akira; Takada, Shinji; Kinjo, Masataka; Taru, Hidenori; Mueller, Ulrike C.; Yamamoto, Tohru; Sobu, Yuriko; Suzuki, Toshiharu 分享 收藏 分享 收藏 Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide脑p3-alc β 肽恢复阿尔茨海默氏淀粉样 β 肽损害的神经元活力Hata, Saori; Saito, Haruka; Kakiuchi, Takeharu; Fukumoto, Dai; Yamamoto, Shigeyuki; Kasuga, Kensaku; Kimura, Ayano; Moteki, Koichi; Abe, Ruriko; Adachi, Shungo; Kinoshita, Shoich; Yoshizawa-Kumagaye, Kumiko; Nishio, Hideki; Saito, Takashi; Saido, Takaomi C.; Yamamoto, Tohru; Nishimura, Masaki; Taru, Hidenori; Sobu, Yuriko; Ohba, Hiroyuki; Nishiyama, Shingo; Harada, Norihiro; Ikeuchi, Takeshi; Tsukada, Hideo; Ouchi, Yasuomi; Suzuki, Toshiharu 分享 收藏 Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2e in an ex vivo murine model of brain ischemiaRahman, S. M. Khaledur; Hussain, Zahir; Morito, Katsuya; Takahashi, Naoko; Sikder, Mohammad Mamun; Tanaka, Tamotsu; Ohta, Ken-ichi; Ueno, Masaki; Takahashi, Hiroo; Yamamoto, Tohru; Murakami, Makoto; Uyama, Toru; Ueda, Natsuo 分享 收藏 Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic strokeTakahashi, Hiroo; Asahina, Ryo; Fujioka, Masayuki; Matsui, Takeshi K.; Kato, Shigeki; Mori, Eiichiro; Hioki, Hiroyuki; Yamamoto, Tohru; Kobayashi, Kazuto; Tsuboi, Akio 分享 收藏 分享 收藏 Amyloidogenic processing of amyloid ? protein precursor (APP) is enhanced in the brains of alcadein ??deficient miceGotoh, Naoya; Saito, Yuhki; Hata, Saori; Saito, Haruka; Ojima, Daiki; Murayama, Chiaki; Shigeta, Mayo; Abe, Takaya; Konno, Daijiro; Matsuzaki, Fumio; Suzuki, Toshiharu; Yamamoto, Tohru 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Loss of Synapse Repressor MDGA1 Enhances Perisomatic Inhibition, Confers Resistance to Network Excitation, and Impairs Cognitive FunctionConnor, Steven A.; Ammendrup-Johnsen, Ina; Kishimoto, Yasushi; Tari, Parisa Karimi; Cvetkovska, Vedrana; Harada, Takashi; Ojima, Daiki; Yamamoto, Tohru; Wang, Yu Tian; Craig, Ann Marie 分享 收藏 Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2Connor, Steven A.; Ammendrup-Johnsen, Ina; Chan, Allen W.; Kishimoto, Yasushi; Murayama, Chiaki; Kurihara, Naokazu; Tada, Atsushi; Ge, Yuan; Lu, Hong; Yan, Ryan; Ledue, Jeffrey M.; Matsumoto, Hirotaka; Kiyonari, Hiroshi; Kirino, Yutaka; Matsuzaki, Fumio; Suzuki, Toshiharu; Murphy, Timothy H.; Wang, Yu Tian; Yamamoto, Tohru; Craig, Ann Marie 分享 收藏 分享 收藏 Cytoplasmic Fragment of Alcadein α Generated by Regulated Intramembrane Proteolysis Enhances Amyloid β-Protein Precursor (APP) Transport into the Late Secretory Pathway and Facilitates APP CleavageTakei, Norio; Sobu, Yuriko; Kimura, Ayano; Urano, Satomi; Piao, Yi; Araki, Yoichi; Taru, Hidenori; Yamamoto, Tohru; Hata, Saori; Nakaya, Tadashi; Suzuki, Toshiharu 分享 收藏 Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport神经元APP轴突运输的定量分析: JIP1在增强APP顺行运输中的作用Chiba, Kyoko; Araseki, Masahiko; Nozawa, Keisuke; Furukori, Keiko; Araki, Yoichi; Matsushima, Takahide; Nakaya, Tadashi; Hata, Saori; Saito, Yuhki; Uchida, Seiichi; Okada, Yasushi; Nairn, Angus C.; Davis, Roger J.; Yamamoto, Tohru; Kinjo, Masataka; Taru, Hidenori; Suzuki, Toshiharu 分享 收藏 Increased Levels of Plasma p3-Alcα35, a Major Fragment of Alcadeinα by γ-Secretase Cleavage, in Alzheimer's DiseaseOmori, Chiori; Kaneko, Madoka; Nakajima, Etsuko; Akatsu, Hiroyasu; Waragai, Masaaki; Maeda, Masahiro; Morishima-Kawashima, Maho; Saito, Yuhki; Nakaya, Tadashi; Taru, Hidenori; Yamamoto, Tohru; Asada, Takashi; Hata, Saori; Suzuki, Toshiharu 分享 收藏 分享 收藏 
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