R. Stephen Lloyd - Publications, H-index & Citations

R. Stephen Lloyd

Oregon Health & Science University

61H指数

372论文数

1.2W被引数

收录论文 109

发表时间

A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad 双功能DNA糖基化酶中具有进化保守的天冬氨酸-赖氨酸二聚体的统一催化机制

Nature Communications

IF15.7

2026-07-15

OAAI

Aleem Syed; Leonardo F. Serafim; Andrew S. Arvai; Irina G. Minko; Henry Y. H. Tang; Joy L. Huffman; Clifford D. Mol; Kenichi Hitomi; Altaf H. Sarker; Sudip Parikh; Chi-Lin Tsai; Albino Bacolla; David S. Shin; Richard P. Cunningham; Shigenori Iwai; Dipanjan Chowdhury; R. Stephen Lloyd; Ivaylo Ivanov; John A. Tainer

A metal ion-dependent mechanism promoting gain of function in NEIL1 variants 金属离子依赖性机制促进NEIL1变体的功能获得

International Journal of Radiation Biology

IF2.4

2026-01-01

PREAI

Zuckerman, Jamie T.; Minko, Irina G.; Lybrand, Terry P.; Egli, Martin; McCullough, Amanda K.; Lloyd, R. Stephen

Role of NEIL1 in genome maintenance (vol 148, 103820, 2025)NEIL1在基因组维持中的作用（卷148，103820，2025）

DNA REPAIR

IF2.7

2025-05-01

PREAI

McCullough, Amanda K.; Minko, Irina G.; Luzadder, Michael M.; Zuckerman, Jamie T.; Vartanian, Vladimir L.; Jaruga, Pawel; Dizdaroglu, Miral; Lloyd, R. Stephen

Inhibition by 4-(4-Bromo-2-oxo-3H-benzimidazol-1-yl)-N-(4-iodophenyl)piperidine-1-carboxamide (TH5487) of the Activity of Human 8-Oxoguanine DNA Glycosylase-1 (OGG1) for the Excision of 2,6-Diamino-4-hydroxy-5-formamidopyrimidine, 4,6-Diamino-5-formamidopyrimidine, and 8-Oxoguanine from Oxidatively Damaged DNA 4-(4-溴-2-氧代-3H-苯并咪唑-1-基)-N-(4-碘苯基)哌啶-1-甲酰胺（TH5487）对人8-氧代鸟嘌呤DNA糖基化酶-1（OGG1）活性的抑制，该酶活性针对氧化损伤DNA中2,6-二氨基-4-羟基-5-甲酰氨基嘧啶、4,6-二氨基-5-甲酰氨基嘧啶和8-氧代鸟嘌呤的切除。

BIOCHEMISTRY

IF3

2025-04-03

OAAI

Jaruga, Pawel; Kant, Melis; Luzadder, Michael M.; Lloyd, R. Stephen; Boldogh, Istvan; Dizdaroglu, Miral

Role of NEIL1 in genome maintenance NEIL1在基因组维持中的作用

DNA REPAIR

IF2.7

2025-04-01

PREAI

Mccullough, Amanda K.; Minko, Irina G.; Luzadder, Michael M.; Zuckerman, Jamie T.; Vartanian, Vladimir L.; Jaruga, Pawel; Dizdaroglu, Miral; Lloyd, R. Stephen

Aflatoxin B1-induced DNA adduct formation in murine kidney and liver

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

IF4.2

2025-03-01

PREAI

Jaruga, Pawel; Vartanian, Vladimir L.; Minko, Irina G.; Dizdaroglu, Miral; Lloyd, R. Stephen

The Distinct Roles of NEIL1 and XPA in Limiting Aflatoxin B1-Induced Mutagenesis in Mice

MOLECULAR CANCER RESEARCH

IF4.7

2024-10-10

PREAI

Luzadder, Michael M.; Minko, Irina G.; Vartanian, Vladimir L.; Davenport, Marten; Fedorov, Lev M.; Mccullough, Amanda K.; Lloyd, R. Stephen

Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in South Asian populations

DNA REPAIR

IF2.7

2024-07-01

PREAI

Zuckerman, Jamie T.; Jackson, Asia Sage; Minko, Irina G.; Kant, Melis; Jaruga, Pawel; Stone, Michael P.; Dizdaroglu, Miral; Mccullough, Amanda K.; Lloyd, R. Stephen

Mass Spectrometry-Based Method to Measure Aflatoxin B1 DNA Adducts in Formalin-Fixed Paraffin-Embedded Tissues

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2024-03-18

PREAI

Bellamri, Medjda; Yao, Lihua; Tomar, Rachana; Vartanian, Vladimir; Rizzo, Carmelo J.; Stone, Michael P.; Groopman, John D.; Lloyd, R. Stephen; Turesky, Robert J.

Interaction of mitoxantrone with abasic sites - DNA strand cleavage and inhibition of apurinic/apyrimidinic endonuclease 1, APE1

DNA REPAIR

IF2.7

2024-01-01

OAAI

Minko, Irina G.; Moellmer, Samantha A.; Luzadder, Michael M.; Tomar, Rachana; Stone, Michael P.; Mccullough, Amanda K.; Lloyd, R. Stephen

Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations

DNA REPAIR

IF2.7

2023-09-01

OAAI

Zuckerman, Jamie T.; Minko, Irina G.; Kant, Melis; Jaruga, Pawel; Stone, Michael P.; Dizaroglu, Miral; McCullough, Amanda K.; Lloyd, R. Stephen

Synthesis and Characterization of 15N5-Labeled Aflatoxin B1-Formamidopyrimidines and Aflatoxin B1-N7-Guanine from a Partial Double-Stranded Oligodeoxynucleotide as Internal Standards for Mass Spectrometric Measurements

ACS OMEGA

IF4.3

2023-04-11

OAAI

Jaruga, Pawel; Tomar, Rachana; Kant, Melis; Vartanian, Vladimir; Sexton, Benjamin; Rizzo, Carmelo J.; Turesky, Robert J.; Stone, Michael P.; Lloyd, R. Stephen; Dizdaroglu, Miral

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase hNEIL1糖基化酶对N-(2-脱氧-d-红戊呋喃糖基)-尿素损伤的碱基切除修复

NUCLEIC ACIDS RESEARCH

IF13.1

2023-04-04

OAAI

Tomar, Rachana; Minko, Irina G.; Sharma, Pankaj; Kellum Jr, Andrew H.; Lei, Li; Harp, Joel M.; Iverson, T. M.; Lloyd, R. Stephen; Egli, Martin; Stone, Michael P.

Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase ζ

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

114

OAAI

Washington, MT; Minko, IG; Johnson, RE; Haracska, L; Harris, TM; Lloyd, RS; Prakash, S; Prakash, L

Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases ι and κ

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Wolfle, WT; Johnson, RE; Minko, IG; Lloyd, RS; Prakash, S; Prakash, L

Human DNA polymerase ι promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Wolfle, WT; Johnson, RE; Minko, IG; Lloyd, RS; Prakash, S; Prakash, L

Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases ι and κ

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

120

OAAI

Washington, MT; Minko, IG; Johnson, RE; Wolfle, WT; Harris, TM; Lloyd, RS; Prakash, S; Prakash, L

Polymorphic variant Asp239Tyr of human DNA glycosylase NTHL1 is inactive for removal of a variety of oxidatively-induced DNA base lesions from genomic DNA

DNA REPAIR

IF2.7

2022-09-01

PREAI

Kant, Melis; Quintana, Victoria; Coskun, Erdem; Jaruga, Pawel; Lloyd, R. Stephen; Sweasy, Joann B.; Dizdaroglu, Miral

DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model

DNA REPAIR

IF2.7

2021-09-01

OAAI

Paluri, Sesha L.; Burak, Matthew; Senejani, Alireza G.; Levinson, Madison; Rahim, Tania; Clairmont, Kaylyn; Kashgarian, Michael; Alvarado-Cruz, Isabel; Meas, Rithy; Cardo-Vila, Marina; Zeiss, Caroline; Maher, Stephen; Bothwell, Alfred L. M.; Coskun, Erdem; Kant, Melis; Jaruga, Pawel; Dizdaroglu, Miral; Lloyd, R. Stephen; Sweasy, Joann B.

Sequence-Based Structural Stability Modulate Biological Processing of AFB1-Fapy-dG Adduct by NEIL1 DNA glycosylase

FASEB JOURNAL

IF4.2

2021-05-14

PREAI

Tomar, Rachana; Minko, Irina; Kellum, Andrew; Voehler, Markus; McCullough, Amanda; Lloyd, R.; Stone, Michael

研究方向