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Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation Leeson-Payne, Alasdair; Iyinikkel, Jean; Malcolm, Cameron; Lam, Brian Y. H.; Sommer, Nadine; Dowsett, Georgina K. C.; de Morentin, Pablo B. Martinez; Thompson, Dawn; Mackenzie, Alasdair; Chianese, Raffaella; Kentistou, Katherine; Gardner, Eugene J.; Perry, John R. B.; Grassmann, Felix; Speakman, John R.; Rochford, Justin J.; Yeo, Giles S. H.; Murray, Fiona; Heisler, Lora K. 分享 收藏
An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans McEwan, Andrew R.; Hing, Benjamin; Erickson, Johanna C.; Hutchings, Greg; Urama, Charity; Norton-Hughes, Emily; D'Ippolito, Mariam; Berry, Susan; Delibegovic, Mirela; Grassmann, Felix; MacKenzie, Alasdair 分享 收藏
The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet McEwan, Andrew; Erickson, Johanna Celene; Davidson, Connor; Heijkoop, Jenny; Turnbull, Yvonne; Delibegovic, Mirela; Murgatroyd, Christopher; MacKenzie, Alasdair 分享 收藏
CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake McEwan, Andrew R.; Davidson, Connor; Hay, Elizabeth; Turnbull, Yvonne; Erickson, Johanna Celene; Marini, Pietro; Wilson, Dana; McIntosh, Andrew M.; Adams, Mark J.; Murgatroyd, Chris; Barrett, Perry; Delibegovic, Mirela; Clarke, Toni-Kim; MacKenzie, Alasdair 分享 收藏
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Early and reversible changes to the hippocampal proteome in mice on a high-fat diet McLean, Fiona H.; Campbell, Fiona M.; Sergi, Domenico; Grant, Christine; Morris, Amanda C.; Hay, Elizabeth A.; MacKenzie, Alasdair; Mayer, Claus D.; Langston, Rosamund F.; Williams, Lynda M. 分享 收藏
Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4 Sergi, Domenico; Morris, Amanda C.; Kahn, Darcy E.; McLean, Fiona H.; Hay, Elizabeth A.; Kubitz, Phil; MacKenzie, Alasdair; Martinoli, Maria G.; Drew, Janice E.; Williams, Lynda M. 分享 收藏
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In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling 子宫内暴露于香烟烟雾会导致人类胎儿卵巢发育信号异常 Fowler, Paul A.; Childs, Andrew J.; Courant, Frederique; MacKenzie, Alasdair; Rhind, Stewart M.; Antignac, Jean-Philippe; Le Bizec, Bruno; Filis, Panagiotis; Evans, Fergus; Flannigan, Samantha; Maheshwari, Abha; Bhattacharya, Siladitya; Monteiro, Ana; Anderson, Richard A.; O'Shaughnessy, Peter J. 分享 收藏
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Allele-specific Differences in Activity of a Novel Cannabinoid Receptor 1 (CNR1) Gene Intronic Enhancer in Hypothalamus, Dorsal Root Ganglia, and Hippocampus Nicoll, Gemma; Davidson, Scott; Shanley, Lynne; Hing, Ben; Lear, Marissa; McGuffin, Peter; Ross, Ruth; MacKenzie, Alasdair 分享 收藏
Differential Activity by Polymorphic Variants of a Remote Enhancer that Supports Galanin Expression in the Hypothalamus and Amygdala: Implications for Obesity, Depression and Alcoholism Davidson, Scott; Lear, Marissa; Shanley, Lynne; Hing, Benjamin; Baizan-Edge, Amanda; Herwig, Annika; Quinn, John P.; Breen, Gerome; McGuffin, Peter; Starkey, Andrew; Barrett, Perry; MacKenzie, Alasdair 分享 收藏
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Genome-Wide Association Study of Major Recurrent Depression in the UK Population Lewis, Cathryn M.; Ng, Mandy Y.; Butler, Amy W.; Cohen-Woods, Sarah; Uher, Rudolf; Pirlo, Katrina; Weale, Michael E.; Schosser, Alexandra; Paredes, Ursula M.; Rivera, Margarita; Craddock, Nicholas; Owen, Mike J.; Jones, Lisa; Jones, Ian; Korszun, Ania; Aitchison, Katherine J.; Shi, Jianxin; Quinn, John P.; MacKenzie, Alasdair; Vollenweider, Peter; Waeber, Gerard; Heath, Simon; Lathrop, Mark; Muglia, Pierandrea; Barnes, Michael R.; Whittaker, John C.; Tozzi, Federica; Holsboer, Florian; Preisig, Martin; Farmer, Anne E.; Breen, Gerome; Craig, Ian W.; McGuffin, Peter 分享 收藏
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