Alexander Rodríguez‐López

9800 medical center drive

20H指数

108论文数

1.1K被引数

收录论文 42

发表时间

Reactivation of Human X-Linked Gene and Stable X-Chromosome Inactivation Observed in Generation and Differentiation of iPSCs from a Female Patient with HNRNPH2 Mutation 人类X连锁基因的再激活和X染色体稳定的失活，在携带HNRNPH2突变的女性患者来源的诱导多能干细胞（iPSCs）的生成和分化过程中被观察到。

Cells 2025, Vol. 14, Page 1486

IF5.2

2025-09-26

OAAI

Guibin Chen; Alexander Rodriguez-Lopez; Darawalee Wangsa; Richa Madan Lomash; Xiuli Huang; Catherine Z. Chen; Rodney A. Bowling, Jr.; Neda Ghousifam; Courtney J. Banks; Kerstin A. Hurd; Jizhong Zou; Wei Zheng

Novel human recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in a glyco-engineered Escherichia coli strain

HELIYON

IF3.6

2024-06-01

OAAI

Pimentel-Vera, Luisa N.; Rodriguez-Lopez, Alexander; Espejo-Mojica, Angela J.; Ramirez, Aura Maria; Cardona, Carolina; Reyes, Luis H.; Tomatsu, Shunji; Jaroentomeechai, Thapakorn; DeLisa, Matthew P.; Sanchez, Oscar F.; Almeciga-Diaz, Carlos J.

Metabolic impact of infant formulas in young infants. An outlook from the urine metabolome

HELIYON

IF3.6

2022-09-01

OAAI

Marcela Calvo Barbosa, Angie; Casallas Cortes, Stefany; Pulido, Ninna; Yaneth Parra, Martha; Rodriguez-Lopez, Alexander; Guevara-Morales, Johana; Yaneth Echeverri-Pena, Olga

Iduronate-2-sulfatase interactome: validation by yeast two-hybrid assay

HELIYON

IF3.6

2022-03-01

OAAI

Benincore-Florez, Eliana; El-Azaz, Jorge; Solarte, Gabriela Alejandra; Rodriguez, Alexander; Reyes, Luis H.; Almeciga-Diaz, Carlos Javier; Cardona-Ramirez, Carolina

1H-Nuclear Magnetic Resonance Analysis of Urine as Diagnostic Tool for Organic Acidemias and Aminoacidopathies

METABOLITES

IF3.7

2021-12-20

OAAI

Pulido, Ninna; Guevara-Morales, Johana M.; Rodriguez-Lopez, Alexander; Pulido, Alvaro; Diaz, Jhon; Edrada-Ebel, Ru Angelie; Echeverri-Pena, Olga Y.

Use of a neuron-glia genome-scale metabolic reconstruction to model the metabolic consequences of the Arylsulphatase a deficiency through a systems biology approach

HELIYON

IF3.6

2021-07-01

OAAI

Echeverri-Pena, Olga Y.; Salazar-Barreto, Diego A.; Rodriguez-Lopez, Alexander; Gonzalez, Janneth; Almeciga-Diaz, Carlos J.; Verano-Guevara, Cristian H.; Barrera, Luis A.

Bromocriptine as a Novel Pharmacological Chaperone for Mucopolysaccharidosis IV A 溴隐亭作为粘多糖贮积症IV a的新型药理伴侣

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-06-24

OAAI

Olarte-Avellaneda, Sergio; Cepeda Del Castillo, Jacobo; Felipe Rojas-Rodriguez, Andres; Sanchez, Oscar; Rodriguez-Lopez, Alexander; Suarez Garcia, Diego A.; Salazar Pulido, Luz Mary; Almeciga-Diaz, Carlos J.

Characterization of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase Produced in Pichia pastoris as Potential Enzyme for Mucopolysaccharidosis IVA Treatment

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2019-08-01

PREAI

Rodriguez-Lopez, Alexander; Pimentel-Vera, Luisa N.; Espejo-Mojica, Angela J.; Van Hecke, Annelies; Tiels, Petra; Tomatsu, Shunji; Callewaert, Nico; Almeciga-Diaz, Carlos J.

Identification of Ezetimibe and Pranlukast as Pharmacological Chaperones for the Treatment of the Rare Disease Mucopolysaccharidosis Type IVA

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-06-12

PREAI

Almeciga-Diaz, Carlos J.; Hidalgo, Oscar A.; Olarte-Avellaneda, Sergio; Rodriguez-Lopez, Alexander; Guzman, Esteban; Garzon, Rafael; Natalia Pimentel-Vera, Luisa; Alejandra Puentes-Tellez, Maria; Felipe Rojas-Rodriguez, Andres; Gorshkov, Kirill; Li, Rong; Zheng, Wei

Identification of the iduronate-2-sulfatase proteome in wild-type mouse brain

HELIYON

IF3.6

2019-05-01

OAAI

Cardona, Carolina; Benincore, Eliana; Pimentel, Natalia; Reyes, Luis H.; Patarroyo, Camilo; Rodriguez-Lopez, Alexander; Martin-Rufian, M.; Barrera, Luis Alejandro; Almeciga-Diaz, Carlos J.

Chondrocytes and cardiomyocytes derived from Morquio syndrome type A induced pluripotent stem cells (iPCS)

MOLECULAR GENETICS AND METABOLISM

IF3.5

2019-02-01

PREAI

Almeciga-Diaz, Carlos J.; Rodriguez-Lopez, Alexander; Baskfield, Amanda; Li, Rong; Zheng, Wei

Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2018-09-17

OAAI

Vu, Mylinh; Li, Rong; Baskfield, Amanda; Lu, Billy; Farkhondeh, Atena; Gorshkov, Kirill; Motabar, Omid; Beers, Jeanette; Chen, Guokai; Zou, Jizhong; Espejo-Mojica, Angela J.; Rodriguez-Lopez, Alexander; Almeciga-Diaz, Carlos J.; Barrera, Luis A.; Jiang, Xuntian; Ory, Daniel S.; Marugan, Juan J.; Zheng, Wei

Research, diagnosis and education in inborn errors of metabolism in Colombia: 20 years' experience from a reference center

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2018-08-16

OAAI

Echeverri, Olga Y.; Guevara, Johana M.; Espejo-Mojica, Angela J.; Ardila, Andrea; Pulido, Ninna; Reyes, Magda; Rodriguez-Lopez, Alexander; Almeciga-Diaz, Carlos J.; Barrera, Luis A.

Impact of Psychosocial Characteristics on Survival in Patients Undergoing Left Ventricular Assist Device (LVAD) Implantation

JOURNAL OF CARDIAC FAILURE

IF8.2

2018-08-01

PREAI

Rodriguez, Alexander; Wehbe, Ramsey; Anderson, Allen; Ghafourian, Kambiz; Okwuosa, Ike; Wilcox, Jane; Vorovich, Esther; Hubert, Adam; Duc Pham; Rich, Jonathan D.

Production and characterization of a human lysosomal recombinant iduronate-2-sulfatase produced in Pichia pastoris

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

IF2.7

2018-04-23

PREAI

Pimentel, Natalia; Rodriguez-Lopez, Alexander; Diaz, Sergio; Losada, Juan C.; Diaz-Rincon, Dennis J.; Cardona, Carolina; Espejo-Mojica, Angela J.; Ramirez, Aura M.; Ruiz, Fredy; Landazuri, Patricia; Poutou-Pinales, Raul A.; Cordoba-Ruiz, Henry A.; Almeciga-Diaz, Carlos J.; Barrera-Avellaneda, Luis A.

Characterization of two potential pharmacological chaperones for N-acetylgalactosamine-6-sulfate sulfates (GALNS) enzyme

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Almeciga-Diaz, Carlos J.; Hidalgo, Oscar A.; Olarte-Avellaneda, Sergio; Rodriguez-Lopez, Alexander

Recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme produced in pichia pastoris as an alternative for Morquio syndrome type A ERT

MOLECULAR GENETICS AND METABOLISM

IF3.5

2018-02-01

PREAI

Rodriguez-Lopez, Alexander; Pimentel-Vera, Luisa N.; Espejo-Mojica, Angela J.; Hidalgo, Oscar A.; Tomatsu, Shunji; Almeciga-Diaz, Carlos J.

Production of human recombinant phenylalanine hydroxylase in Lactobacillus plantarum for gastrointestinal delivery

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-11-01

PREAI

Maria Ramirez, Aura; Rodriguez-Lopez, Alexander; Ardila, Andrea; Beltran, Laura; Andres Patarroyo, Camilo; Del Pilar Melendez, Adelina; Fernando Sanchez, Oscar; Javier Almeciga-Diaz, Carlos

Improvement in the production of the human recombinant enzyme N- acetylgalactosamine-6-sulfatase (rhGALNS) in Escherichia coli using synthetic biology approaches

SCIENTIFIC REPORTS

IF3.9

2017-07-19

OAAI

Reyes, Luis H.; Cardona, Carolina; Pimentel, Luisa; Rodriguez-Lopez, Alexander; Almeciga-Diaz, Carlos J.

Human recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in a glycoengineered Escherichia coli strain

MOLECULAR GENETICS AND METABOLISM

IF3.5

2017-01-01

PREAI

Almeciga-Diaz, Carlos J.; Pimentel-Vera, Luisa N.; Rodriguez-Lopez, Alexander; Espejo-Mojica, Angela; Ramirez, Aura M.; Cardona, Carolina; Reyes, Luis H.; DeLisa, Matthew P.; Sanchez, Oscar F.

研究方向