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Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus Xie, Jenny H.; Zhang, Yifan; Loubeau, Martine; Mangan, Paul; Heimrich, Elizabeth; Tovar, Christian; Zhou, Xiadi; Madia, Priyanka; Doyle, Michael; Dudhgaonkar, Shailesh; Rudra, Anjuman; Subramani, Siva; Young, James; Salter-Cid, Luisa; Malek, Thomas R.; Struthers, Mary 分享 收藏
Comparison of Ensemble and Single Molecule Methods for Particle Characterization and Binding Analysis of a PEGylated Single-Domain Antibody Schneeweis, Lumelle A.; Obenauer-Kutner, Linda; Kaur, Parminder; Yamniuk, Aaron P.; Tamura, James; Jaffe, Neil; O'Mara, Brian W.; Lindsay, Stuart; Doyle, Michael; Bryson, James 分享 收藏
Hydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeutics Iacob, Roxana E.; Krystek, Stanley R.; Huang, Richard Y-C; Wei, Hui; Tao, Li; Lin, Zheng; Morin, Paul E.; Doyle, Michael L.; Tymiak, Adrienne A.; Engen, John R.; Chen, Guodong 分享 收藏
A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor Emanuel, Stuart L.; Engle, Linda J.; Chao, Ginger; Zhu, Rong-Rong; Cao, Carolyn; Lin, Zheng; Yamniuk, Aaron; Hosbach, Jennifer; Brown, Jennifer; Fitzpatrick, Elizabeth; Gokemeijer, Jochem; Morin, Paul; Morse, Brent; Carvajal, Irvith M.; Fabrizio, David; Wright, Martin C.; Das Gupta, Ruchira; Gosselin, Michael; Cataldo, Daniel; Ryseck, Rolf P.; Doyle, Michael L.; Wong, Tai W.; Camphausen, Raymond T.; Cload, Sharon T.; Marsh, H. Nicholas; Gottardis, Marco M.; Furfine, Eric S. 分享 收藏
The Influence of Adnectin Binding on the Extracellular Domain of Epidermal Growth Factor Receptor Iacob, Roxana E.; Chen, Guodong; Ahn, Joomi; Houel, Stephane; Wei, Hui; Mo, Jingjie; Tao, Li; Cohen, Daniel; Xie, Dianlin; Lin, Zheng; Morin, Paul E.; Doyle, Michael L.; Tymiak, Adrienne A.; Engen, John R. 分享 收藏
Kinetic Exclusion Analysis (KinExa) of Avidity Enhancement of a Multi-Valent Adnectin Binding to Clustered Receptors on CHO Cells Schneeweis, Lumelle A.; Hatcher, Sandra V.; Barnhart, Bryan; Glass, Thomas R.; Cheng, Lin; Blum, Benjamin; Lawrence, Eric; Ryseck, Rolf; Camphausen, Ray; Abramczyk, Bozena M.; Della Pietra, Anthony; Corbett, Martin J.; McDonagh, Thomas; Doyle, Michael L.; Bryson, James 分享 收藏
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Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor® technology Carver, TE; Bordeau, B; Cummings, MD; Petrella, EC; Pucci, MJ; Zawadzke, LE; Dougherty, BA; Tredup, JA; Bryson, JW; Yanchunas, J; Doyle, ML; Witmer, MR; Nelen, MI; DesJarlais, RL; Jaeger, EP; Devine, H; Asel, ED; Springer, BA; Bone, R; Salemme, FR; Todd, MJ 分享 收藏
Selective binding and oligomerization of the murine granulocyte colony-stimulating factor receptor by a low molecular weight, nonpeptidyl ligand Doyle, ML; Tian, SS; Miller, SG; Kessler, L; Baker, AE; Brigham-Burke, MR; Dillon, SB; Duffy, KJ; Keenan, RM; Lehr, R; Rosen, J; Schneeweis, LA; Trill, J; Young, PR; Luengo, JI; Lamb, P 分享 收藏
Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein Xiang, SH; Kwong, PD; Gupta, R; Rizzuto, CD; Casper, DJ; Wyatt, R; Wang, LP; Hendrickson, WA; Doyle, ML; Sodroski, J 分享 收藏
Potent, novel in vitro inhibitors of the Pseudomonas aeruginosa deacetylase LpxC Kline, T; Andersen, NH; Harwood, EA; Bowman, J; Malanda, A; Endsley, S; Erwin, AL; Doyle, M; Fong, S; Harris, AL; Mendelsohn, B; Mdluli, K; Raetz, CRH; Stover, CK; Witte, PR; Yabannavar, A; Zhu, SG 分享 收藏
Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae β-ketoacyl-acyl carrier protein synthase III (FabH) Khandekar, SS; Gentry, DR; Van Aller, GS; Warren, P; Xiang, H; Silverman, C; Doyle, ML; Chambers, PA; Konstantinidis, AK; Brandt, M; Daines, RA; Lonsdale, JT 分享 收藏
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Temperature-sensitive differential affinity of TRAIL for its receptors - DR5 is the highest affinity receptor Truneh, A; Sharma, S; Silverman, C; Khandekar, S; Reddy, MP; Deen, KC; Mclaughlin, MM; Srinivasula, SM; Livi, GP; Marshall, LA; Alnemri, ES; Williams, WV; Doyle, ML 分享 收藏