Andrea J. Tenner - Publications, H-index & Citations

Andrea J. Tenner

university of california irvine

76H指数

280论文数

1.8W被引数

收录论文 90

发表时间

Complement-dependent phagocytosis in the clearance of various cellular targets 补体依赖性吞噬作用在清除各种细胞靶标中的作用

Protein & Cell

IF0

2026-08-22

OAAI

Marfa Blanter; Max L B Grönloh; Pedro E Marques; Suzan H M Rooijakkers; Andrea J Tenner; Leendert A Trouw

Young Adult Microglial Deletion of C1q Reduces Engulfment of Synapses and Partially Mitigates Cognitive Impairment in an Aggressive Alzheimer's Disease Mouse Model 成年小鼠小胶质细胞C1q的删除减少了突触的吞噬，并在具有攻击性的阿尔茨海默病小鼠模型中部分缓解了认知障碍

Glia

IF5.1

2026-08-11

OAAI

Tiffany J. Petrisko; Shu-Hui Chu; Angela Gomez-Arboledas; Blossom Zhang; Andrea J. Tenner

The TREM2 R47H variant is associated with liver-plasma-brain axis dyshomeostasis in the 5xFAD mouse model of Alzheimer’s disease TREM2 R47H变异与阿尔茨海默病5xFAD小鼠模型中肝-血浆-脑轴失衡相关

Neurobiology of Aging

IF3.5

2026-04-29

OAAI

Gina Faraci; Benjamin Goodfriend; Joseph Bishop; Michael Vu; Julio Avelar-Barragan; Sage Dunham; Jason Rothman; Katrine Whiteson; Amrita K Cheema; Giedre Milinkeviciute; Andrea J Tenner; Frank M LaFerla; Grant R MacGregor; Kim N Green; Mark Mapstone

Knowing the enemy: strategic targeting of complement to treat Alzheimer disease 了解敌人：利用补体进行靶向治疗以治疗阿尔茨海默病

NATURE REVIEWS NEUROLOGY

IF33.1

2025-03-24

PREAI

Tenner, Andrea J.; Petrisko, Tiffany J.

APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology APOE Christchurch增强了与疾病相关的小胶质细胞对斑块的反应，但抑制了对tau病理的反应

MOLECULAR NEURODEGENERATION

IF17.5

2025-01-22

OAAI

Tran, Kristine M.; Kwang, Nellie E.; Butler, Claire A.; Gomez-Arboledas, Angela; Kawauchi, Shimako; Mar, Cassandra; Chao, Donna; Barahona, Rocio A.; Da Cunha, Celia; Tsourmas, Kate I.; Shi, Zechuan; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Alcantara, Joshua A.; Neumann, Jonathan; Duong, Duc M.; Seyfried, Nicholas T.; Tenner, Andrea J.; Laferla, Frank M.; Hohsfield, Lindsay A.; Swarup, Vivek; Macgregor, Grant R.; Green, Kim N.

C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer's disease mouse model

NATURE COMMUNICATIONS

IF15.7

2024-08-15

OAAI

Schartz, Nicole D.; Liang, Heidi Y.; Carvalho, Klebea; Chu, Shu-Hui; Mendoza-Arvilla, Adrian; Petrisko, Tiffany J.; Gomez-Arboledas, Angela; Mortazavi, Ali; Tenner, Andrea J.

Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAβ-KI) mice AD基因型与人类 β 淀粉样蛋白敲入 (haβ-ki) 小鼠的微生物组之间的性别特异性关联

ALZHEIMERS & DEMENTIA

IF11.1

2024-04-04

OAAI

Dunham, Sage J. B.; Avelar-Barragan, Julio; Rothman, Jason A.; Adams, Eric D.; Faraci, Gina; Forner, Stefania; Kawauchi, Shimako; Tenner, Andrea J.; Green, Kim N.; LaFerla, Frank M.; MacGregor, Grant R.; Mapstone, Mark; Whiteson, Katrine L.

The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-20

OAAI

Butler, Claire A.; Arvilla, Adrian Mendoza; Milinkeviciute, Giedre; Da Cunha, Celia; Kawauchi, Shimako; Rezaie, Narges; Liang, Heidi Y.; Javonillo, Dominic; Thach, Annie; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Gomez-Arboledas, Angela; Henningfield, Caden M.; Hohsfield, Lindsay A.; Mapstone, Mark; Tenner, Andrea J.; LaFerla, Frank M.; Mortazavi, Ali; MacGregor, Grant R.; Green, Kim N.

BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-09

OAAI

Garcia-Agudo, Laura Fernandez; Shi, Zechuan; Smith, Ian F.; Kramar, Eniko A.; Tran, Katelynn; Kawauchi, Shimako; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Liang, Heidi Yahan; Da Cunha, Celia; Milinkeviciute, Giedre; Morabito, Samuel; Miyoshi, Emily; Rezaie, Narges; Gomez-Arboledas, Angela; Arvilla, Adrian Mendoza; Ghaemi, Daryan Iman; Tenner, Andrea J.; LaFerla, Frank M.; Wood, Marcelo A.; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N.

Genetic diversity promotes resilience in a mouse model of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-03-01

OAAI

Soni, Neelakshi; Hohsfield, Lindsay A.; Tran, Kristine M.; Kawauchi, Shimako; Walker, Amber; Javonillo, Dominic; Phan, Jimmy; Matheos, Dina; Da Cunha, Celia; Uyar, Asli; Milinkeviciute, Giedre; Gomez-Arboledas, Angela; Tran, Katelynn; Kaczorowski, Catherine C.; Wood, Marcelo A.; Tenner, Andrea J.; LaFerla, Frank M.; Carter, Gregory .; Mortazavi, Ali; Swarup, Vivek; MacGregor, Grant R.; Green, Kim N.

C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease

ALZHEIMERS & DEMENTIA

IF11.1

2024-01-26

OAAI

Gomez-Arboledas, Angela; Fonseca, Maria I.; Kramar, Eniko; Chu, Shu-Hui; Schartz, Nicole D.; Selvan, Purnika; Wood, Marcelo A.; Tenner, Andrea J.

Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models

JOURNAL OF NEUROINFLAMMATION

IF10.1

2023-09-19

OAAI

Petrisko, Tiffany J.; Gargus, Matthew; Chu, Shu-Hui; Selvan, Purnika; Whiteson, Katrine L.; Tenner, Andrea J.

Complement in the Brain: Contributions to Neuroprotection, Neuronal Plasticity, and Neuroinflammation

ANNUAL REVIEW OF IMMUNOLOGY

IF33.3

2023-04-26

OAAI

Bohlson, Suzanne S.; Tenner, Andrea J.

A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques 没有隐性剪接的Trem2R47H小鼠模型驱动年龄和疾病依赖性组织损伤和响应于斑块的突触丢失

MOLECULAR NEURODEGENERATION

IF17.5

2023-02-17

OAAI

Tran, Kristine M. M.; Kawauchi, Shimako; Kramar, Eniko A.; Rezaie, Narges; Liang, Heidi Yahan; Sakr, Jasmine S. S.; Gomez-Arboledas, Angela; Arreola, Miguel A. A.; da Cunha, Celia; Phan, Jimmy; Wang, Shuling; Collins, Sherilyn; Walker, Amber; Shi, Kai-Xuan; Neumann, Jonathan; Filimban, Ghassan; Shi, Zechuan; Milinkeviciute, Giedre; Javonillo, Dominic I. I.; Tran, Katelynn; Gantuz, Magdalena; Forner, Stefania; Swarup, Vivek; Tenner, Andrea J. J.; LaFerla, Frank M. M.; Wood, Marcelo A. A.; Mortazavi, Ali; MacGregor, Grant R. R.; Green, Kim N. N.

C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2022-08-17

OAAI

Gomez-Arboledas, Angela; Carvalho, Klebea; Balderrama-Gutierrez, Gabriela; Chu, Shu-Hui; Liang, Heidi Yahan; Schartz, Nicole D.; Selvan, Purnika; Petrisko, Tiffany J.; Pan, Miranda A.; Mortazavi, Ali; Tenner, Andrea J.

Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression

JOURNAL OF NEUROINFLAMMATION

IF10.1

2022-07-11

OAAI

Carvalho, Klebea; Schartz, Nicole D.; Balderrama-Gutierrez, Gabriela; Liang, Heidi Y.; Chu, Shu-Hui; Selvan, Purnika; Gomez-Arboledas, Angela; Petrisko, Tiffany J.; Fonseca, Maria, I; Mortazavi, Ali; Tenner, Andrea J.

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease 阿尔茨海默病3xTg-AD小鼠模型的系统表型和表征

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-01-24

OAAI

Javonillo, Dominic I.; Tran, Kristine M.; Phan, Jimmy; Hingco, Edna; Kramar, Enikoe A.; da Cunha, Celia; Forner, Stefania; Kawauchi, Shimako; Milinkeviciute, Giedre; Gomez-Arboledas, Angela; Neumann, Jonathan; Banh, Crystal E.; Huynh, Michelle; Matheos, Dina P.; Rezaie, Narges; Alcantara, Joshua A.; Mortazavi, Ali; Wood, Marcelo A.; Tenner, Andrea J.; MacGregor, Grant R.; Green, Kim N.; LaFerla, Frank M.

Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research

ALZHEIMERS & DEMENTIA

IF11.1

2021-12-07

OAAI

Gordon, Marcia N.; Heneka, Michael T.; Le Page, Lydia M.; Limberger, Christian; Morgan, David; Tenner, Andrea J.; Terrando, Niccolo; Willette, Auriel A.; Willette, Sara A.

C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex

GLIA

IF5.1

2021-11-11

OAAI

Cong, Qifei; Soteros, Breeanne M.; Huo, Anran; Li, Yang; Tenner, Andrea J.; Sia, Gek Ming

The Role of Complement in Synaptic Pruning and Neurodegeneration

IMMUNOTARGETS AND THERAPY

IF4.4

2021-09-01

OAAI

Gomez-Arboledas, Angela; Acharya, Munjal M.; Tenner, Andrea J.

研究方向