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Combined benznidazole and pentoxifylline therapy improves behavioral and cognitive changes in association with the regulation of systemic inflammatory profile in chronic experimental Chagas disease 联合苯并咪唑和己酮可可碱治疗改善了慢性实验性恰加斯病的行为和认知变化，并与系统性炎症谱的调节相关。 Vilar-Pereira, Glaucia; Castano-Barrios, Leda Margarita; Pereira, Isabela Resende; Da Silva Pinheiro, Ana Paula; Do Espirito Santo Protasio Da Silva, Thayse; Hernandez-Velasco, Lina L.; Silva Grijo Farani, Priscila; Kulkarni, Aditi; Roy, Sourav; Mata Dos Santos, Hilton Antonio; De Oliveira Lopes, Raquel; Tinoco, Luzineide Wanderley; Britto, Constanca; Moreira, Otacilio Cruz; Silva, Andrea Alice; Lannes-Vieira, Joseli 分享 收藏
Genetic diversity of Trypanosoma cruzi in individuals with chronic Chagas disease in the Northern Minas Gerais and Vale do Jequitinhonha regions, Minas Gerais, Brazil 巴西米纳斯吉拉斯州北部米纳斯吉拉斯和杰基廷永河谷地区慢性查加斯病患者中克氏锥虫的遗传多样性 Xavier, Emanuelle de Moura Santos; Araujo, Paula Finamore; Pedras, Jenifer Raiane Silva; da Silva Goncalves, Thainara; de Souza, Nubia Nunes; Ferreira, Ariela Mota; de Oliveira-da Silva, Lea Campos; Sabino, Ester Cerdeira; Nunes, Maria do Carmo Pereira; Ribeiro, Antonio Luiz Pinho; Moreira, Otacilio C.; Vieira, Thallyta Maria 分享 收藏
New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial 苯唑硝唑的新治疗方案用于治疗成人慢性恰加斯病（indeterminate form或伴有轻度心脏进展）患者（NuestroBen研究）：一项III期随机、多中心非劣效性临床试验的方案 Marques, Tayna; Forsyth, Colin; Barreira, Fabiana; Lombas, Carola; Blum de Oliveira, Bethania; Laserna, Monica; Molina, Israel; Bangher, Maria del Carmen; Javier Fernandez, Rosmiro; Lloveras, Susana; Fernandez, Marisa Liliana; Scapellato, Pablo; Patterson, Patricia; Garcia, Wilson; Ortiz, Lourdes; Schijman, Alejandro; Moreira, Otacilio C.; Garcia, Lineth; Viele, Kert; Longhi, Silvia; Vaillant, Michel; Tipple, Craig; Fraisse, Laurent; Silvestre-Sousa, Andrea; Sosa-Estani, Sergio; Pinazo, Maria-Jesus 分享 收藏
Gene deletion as a possible strategy adopted by New World Leishmania infantum to maximize geographic dispersion Florencio, Monique; Chagas, Marne Coimbra Batalha; Guimaraes-Costa, Anderson; Oliveira, Jullyanna; Waclawiak, Ingrid; Oliveira, Thamara K. F.; Saraiva, Elvira Maria; Freitas-Mesquita, Anita Leocadio; Meyer-Fernandes, Jose Roberto; Aragao-Farias, Laura; Trindade, Camilly Enes; Escobar, Patricia Cuervo; do Nascimento, Renata Azevedo; Moreira, Otacilio C.; Ribeiro-Gomes, Flavia Lima; Traub-Cseko, Yara M.; Telleria, Erich Loza; Vaselek, Slavica; Lestinova, Tereza; Volf, Petr; Spath, Gerald F.; Cupolillo, Elisa; Boite, Mariana Cortes 分享 收藏
Serum microRNA 143 and 223 Gene Expression Profiles as Potential Biomarkers in Individuals with Hepatitis and COVID-19 da Silva, Lucas Lima; Leon, Luciane Almeida Amado; da Cruz Moreira, Otacilio; da Costa Nunes Pimentel Coelho, Wagner Luis; da Costa, Vanessa Duarte; Ivantes, Claudia Alexandra Pontes; Pollo-Flores, Priscila; Lewis-Ximenez, Lia Laura; de Paula, Vanessa Salete; Villar, Livia Melo 分享 收藏
Preclinical evaluation of combined therapy with amiodarone and low-dose benznidazole in a mouse model of chronic Trypanosoma cruzi infection Barbosa, Juliana Magalhaes Chaves; Pedra-Rezende, Yasmin; Mata-Santos, Hilton Antonio; Vilar-Pereira, Glaucia; de Melo, Tatiana Galva; Ramos, Isalira Peroba; Gibaldi, Daniel; Moreira, Otacilio C.; Nunes, Daniela Ferreira; Batista, Marcos Meuser; Lannes-Vieira, Joseli; Daliry, Anissa; Salomao, Kelly 分享 收藏
The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi Vilar-Pereira, Glaucia; Gibaldi, Daniel; Castano-Barrios, Leda; da Silva, Andrea Alice; Resende Pereira, Isabela; Cruz Moreira, Otacilio; Britto, Constanca; Mata dos Santos, Hilton Antonio; de Oliveira Lopes, Raquel; Wanderley Tinoco, Luzineide; Oliveira, Wilson; Lannes-Vieira, Joseli 分享 收藏
Efficacy of three benznidazole dosing strategies for adults living with chronic Chagas disease (MULTIBENZ) : an international, randomised, double-blind, phase 2b trial Bosch-Nicolau, Pau; Fernandez, Marisa L.; Sulleiro, Elena; Villar, Juan Carlos; Perez-Molina, Jose A.; Correa-Oliveira, Rodrigo; Sosa-Estani, Sergio; Sanchez-Montalva, Adridn; Bangher, Maria del Carmen; Moreira, Otacilio C.; Salvador, Fernando; Ferreira, Ariela Mota; Eloi-Santos, Silvana Maria; Serre-Delcor, Nuria; Ramirez, Juan Carlos; Silgado, Aroa; Oliveira, Ines; Martin, Oihane; Aznar, Maria Luisa; Ribeiro, Antonio Luiz P.; Almeida, Paulo Emilio Clementino; Chamorro-Tojeiro, Sandra; Espinosa-Pereiro, Juan; de Paula, Alfredo Mauricio Batista; Vaquiro-Herrera, Eliana; Tur, Carmen; Molina, Israel 分享 收藏
SARS-COV-2 P.1 strain infection in lung, breast and colon tumoral patientderived organoids Sassaro, Tayanne F.; Viana, Anael; Zalis, Mariano; Ferreira, Carlos Gil Moreira; Canedo, Jorge; Ferreira, Danielle; Moreira, Aline S.; Mello, Elen; Rondao, Fabiana; Ferreira, Beatriz I.; Moreira, Otacilio C.; Moreira, Daniel A.; Souza, Bruno; Waghabi, Mariana C.; Tilli, Tatiana M. 分享 收藏
Use of PET/CT to detect myocardial inflammation and the risk of malignant arrhythmia in chronic Chagas disease de Oliveira, Renee Sarmento; Moll-Bernardes, Renata; de Brito, Adriana Xavier; Pinheiro, Martha Valeria Tavares; de Almeida, Sergio Altino; Gomes, Natalia Lins da Silva; Terzi, Flavia Vernin de Oliveira; Moreira, Otacilio Cruz; Xavier, Sergio Salles; Rosado-de-Castro, Paulo Henrique; de Sousa, Andrea Silvestre 分享 收藏
Biomarkers and Echocardiographic Predictors of Cardiovascular Outcome in Patients With Chronic Chagas Disease Mendes, Veronica G.; Rimolo, Lorena; de Lima, Ana Carolina B.; Ferreira, Roberto R.; Oliveira, Luciano S.; Nisimura, Lindice M.; Horita, Samuel I. M.; Costa, Andrea R.; da Silva, Gilberto Marcelo S.; Sangenis, Luiz Henrique C.; Mendes, Fernanda S. N. S.; Sousa, Andrea S.; Veloso, Henrique H.; Holanda, Marcelo T.; Mediano, Mauro F. F.; Waghabi, Mariana C.; Garzoni, Luciana R.; Moreira, Otacilio C.; Britto, Constanca; Cunha, Ademir B.; Hasslocher-Moreno, Alejandro Marcel; Saraiva, Roberto M. 分享 收藏
Validation of the NAT Chagas IVD Kit for the Detection and Quantification of Trypanosoma cruzi in Blood Samples of Patients with Chagas Disease Moreira, Otacilio C.; Fernandes, Alice Gomes; Gomes, Natalia Lins da Silva; dos Santos, Carolina Messias; Jacomasso, Thiago; Costa, Alexandre Dias Tavares; Rossetti Nascimento, Lucas de O.; Hasslocher-Moreno, Alejandro Marcel; do Brasil, Pedro Emmanuel Alvarenga Americano; Morello, Luis Gustavo; Marchini, Fabricio Klerynton; Krieger, Marco Aurelio; Britto, Constanca 分享 收藏
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy Oliveira, Ana Carolina; Vicentino, Amanda Roberta Revoredo; Andrade, Daniele; Pereira, Isabela Resende; Saboia-Vahia, Leonardo; Moreira, Otacilio da Cruz; Carvalho-Pinto, Carla Eponina; da Mota, Julia Barbalho; Maciel, Leonardo; Vilar-Pereira, Glaucia; Pesquero, Joao B.; Lannes-Vieira, Joseli; Sirois, Pierre; Campos de Carvalho, Antonio Carlos; Scharfstein, Julio 分享 收藏
PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma Paz, Mariana M.; Ferretti, Giulia D. S.; Martins-Dinis, Mafalda M. C.; Ferreira, Beatriz I. S.; Faier-Pereira, Amanda; Barnoud, Thibaut; Moreira, Otacilio C.; Silva, Jerson L.; Cordeiro, Yraima; Rangel, Luciana P. 分享 收藏
Clinical Profile and Risk Factors for Severe COVID-19 in Hospitalized Patients from Rio de Janeiro, Brazil: Comparison between the First and Second Pandemic Waves Amado, Luciane Almeida; Coelho, Wagner Luis da Costa Nunes Pimentel; Alves, Arthur Daniel Rocha; Carneiro, Vanessa Cristine de Souza; Moreira, Otacilio da Cruz; de Paula, Vanessa Salete; Lemos, Andreza Salvio; Duarte, Larissa Araujo; Gutman, Elisa Gouvea; Fontes-Dantas, Fabricia Lima; Goncalves, Joao Paulo da Costa; Ramos, Carlos Henrique Ferreira; Ramos Filho, Carlos Henrique Ferreira; Cavalcanti, Marta Guimaraes; Amaro, Marisa Pimentel; Kader, Rafael Lopes; Medronho, Roberto de Andrade; Sarmento, Dmitry Jose de Santana; Alves-Leon, Soniza Vieira 分享 收藏
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy Farani, Priscila Silva Grijo; Ferreira, Beatriz Iandra da Silva; Begum, Khodeza; Vilar-Pereira, Glaucia; Pereira, Isabela Resende; Figueroa, Edith Araceli Fernandez; Cardenas-Ovando, Roberto Alejandro; Almeida, Igor C.; Roy, Sourav; Lannes-Vieira, Joseli; Moreira, Otacilio Cruz 分享 收藏
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The Low Variability of Tc24 in Trypanosoma cruzi TcI as an Advantage for Chagas Disease Prophylaxis and Diagnosis in Mexico Becker, Ingeborg; Miranda-Ortiz, Haydee; Fernandez-Figueroa, Edith A.; Sanchez-Montes, Sokani; Colunga-Salas, Pablo; Grostieta, Estefania; Juarez-Gabriel, Javier; Lozano-Sardaneta, Yokomi N.; Arce-Fonseca, Minerva; Rodriguez-Morales, Olivia; Meneses-Ruiz, Gabriela; Pasten-Sanchez, Sergio; Martinez, Irma Lopez; Gonzalez-Guzman, Saul; Paredes-Cervantes, Vladimir; Moreira, Otacilio C.; Finamore-Araujo, Paula; Canseco-Mendez, Julio C.; Coquis-Navarrete, Uriel; Rengifo-Correa, Laura; Gonzalez-Salazar, Constantino; Alfaro-Cortes, Myrna M.; Falcon-Lezama, Jorge A.; Tapia-Conyer, Roberto; Stephens, Christopher R. 分享 收藏
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