James R. Sellers - Publications, H-index & Citations

James R. Sellers

National Heart, Lung, and Blood Institute

81H指数

359论文数

2.2W被引数

收录论文 104

发表时间

Structural basis of nonmuscle myosin-2 autoinhibition mechanisms 非肌球蛋白-2自抑制机制的结构基础

Nature Communications

IF15.7

2026-06-20

OAAI

Sarah M. Heissler; Giovanna Grandinetti; James R. Sellers; Krishna Chinthalapudi

Src-dependent tyrosine-phosphorylation of NM2A has a protective role against bacterial pore-forming toxins Src依赖的NM2A酪氨酸磷酸化在对抗细菌成孔毒素中具有保护作用

PLoS Pathogens

IF4.9

2026-02-23

PREAI

Brito, Claudia; Mesquita, Francisco S.; Pereira, Joana M.; Osorio, Daniel S.; Billington, Neil; Lima, Ricardo R.; Vale-Costa, Silvia; Sellers, James R.; Cabanes, Didier; Carvalho, Ana X.; Sousa, Sandra

Effect of Load on Non-Muscle Myosin 2 Paralog Filaments in a Biomimetic Contractile Actin Array 负载对非肌肉肌球蛋白2 paralogs丝在仿生收缩肌动蛋白阵列中的影响

SMALL

IF12.1

2025-11-01

OAAI

Bleicher, Philip; Han, David; Billington, Neil; Hart, Ryan; Combs, Christian A.; Qazi, Shureed; Chandrasekar, Indra; Knutson, Jay R.; Sellers, James R.

Development of clinically viable non-muscle myosin II small molecule inhibitors 开发临床可行的非肌球蛋白II小分子抑制剂

Cell

IF42.5

2025-07-01

PREAI

Laszlo Radnai; Erica J. Young; Carlos Kikuti; Katalin Toth; Minghai Zhou; Madalyn Hafenbreidel; Rebecca F. Stremel; Li Lin; Paolo Pasetto; Xiaomin Jin; Aagam Patel; Michael Conlon; Sherri B. Briggs; Leïla Heidsieck; H. Lee Sweeney; James Sellers; Teresa Krieger-Burke; William H. Martin; Jay Sisco; Steven Young; Paul Pearson; Gavin Rumbaugh; Gian Luca Araldi; Steven K. Duddy; Michael D. Cameron; Matthew Surman; Anne Houdusse; Patrick R. Griffin; Theodore M. Kamenecka; Courtney A. Miller

Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track Myosin-5改变其步长以沿着不规则的F-肌动蛋白轨道直线运送货物

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-03-20

OAAI

Fineberga, Adam; Takagi, Yasuharu; Thirumurugan, Kavitha; Andrecka, Joanna; Billingtonc, Neil; Young, Gavin; Cole, Daniel; Burgess, Stan A.; Curd, Alistair P.; Hammer, John A.; Sellers, James R.; Kukura, Philipp; Knight, Peter J.

Molecular regulatory mechanism of human myosin-7a

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-10-01

OAAI

Hollo, Alexandra; Billington, Neil; Takagi, Yasuharu; Kengyel, Andras; Sellers, James R.; Liu, Rong

A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-09-01

OAAI

Das, Samprita; Mallick, Ditipriya; Sarkar, Sourav; Billington, Neil; Sellers, James R.; Jana, Siddhartha S.

A gene duplication of a septin reveals a developmentally regulated filament length control mechanism

JOURNAL OF CELL BIOLOGY

IF6.4

2023-02-14

OAAI

Cannon, Kevin S.; Vargas-Muniz, Jose M.; Billington, Neil; Seim, Ian; Ekena, Joanne; Sellers, James R.; Gladfelter, Amy. S.

Flagella-like beating of actin bundles driven by self-organized myosin waves

NATURE PHYSICS

IF18.4

2022-08-08

OAAI

Pochitaloff, Marie; Miranda, Martin; Richard, Mathieu; Chaiyasitdhi, Atitheb; Takagi, Yasuharu; Cao, Wenxiang; De la Cruz, Enrique M.; Sellers, James R.; Joanny, Jean-Francois; Juelicher, Frank; Blanchoin, Laurent; Martin, Pascal

Pericentrin interacts with Kinesin-1 to drive centriole motility

JOURNAL OF CELL BIOLOGY

IF6.4

2022-08-05

OAAI

Hannaford, Matthew R.; Liu, Rong; Billington, Neil; Swider, Zachary T.; Galletta, Brian J.; Fagerstrom, Carey J.; Combs, Christian; Sellers, James R.; Rusan, Nasser M.

Cryo-EM structure of the autoinhibited state of myosin-2

SCIENCE ADVANCES

IF12.5

2021-12-24

OAAI

Heissler, Sarah M.; Arora, Amandeep S.; Billington, Neil; Sellers, James R.; Chinthalapudi, Krishna

Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II

ACS CHEMICAL BIOLOGY

IF3.8

2021-09-24

PREAI

Radnai, Laszlo; Surman, Matthew; Hafenbreidel, Madalyn; Young, Erica J.; Stremel, Rebecca F.; Lin, Li; Bdiri, Bilel; Pasetto, Paolo; Jin, Xiaomin; Geedy, Mackenzie; Partridge, Joni-Rae; Patel, Aagam; Conlon, Michael; Sellers, James R.; Cameron, Michael D.; Rumbaugh, Gavin; Griffin, Patrick R.; Kamenecka, Theodore M.; Miller, Courtney A.

The formin inhibitor SMIFH2 inhibits members of the myosin superfamily

JOURNAL OF CELL SCIENCE

IF3.6

2021-04-27

OAAI

Nishimura, Yukako; Shi, Shidong; Zhang, Fang; Liu, Rong; Takagi, Yasuharu; Bershadsky, Alexander D.; Viasnoff, Virgile; Sellers, James R.

A binding protein regulates myosin-7a dimerization and actin bundle assembly

NATURE COMMUNICATIONS

IF15.7

2021-01-25

OAAI

Liu, Rong; Billington, Neil; Yang, Yi; Bond, Charles; Hong, Amy; Siththanandan, Verl; Takagi, Yasuharu; Sellers, James R.

The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Jiang, Fangfang; Takagi, Yasuharu; Shams, Arik; Heissler, Sarah M.; Friedman, Thomas B.; Sellers, James R.; Bird, Jonathan E.

Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells

CURRENT BIOLOGY

IF7.5

2020-07-01

OAAI

Aguilar-Cuenca, Rocio; Llorente-Gonzalez, Clara; Chapman, Jessica R.; Talayero, Vanessa C.; Garrido-Casado, Marina; Delgado-Arevalo, Cristina; Millan-Salanova, Maria; Shabanowitz, Jeffrey; Hunt, Donald F.; Sellers, James R.; Heissler, Sarah M.; Vicente-Manzanares, Miguel

Competition between kinesin-1 and myosin-V defines Drosophila posterior determination

ELIFE

IF0

2020-02-14

OAAI

Lu, Wen; Lakonishok, Margot; Liu, Rong; Billington, Neil; Rich, Ashley; Glotzer, Michael; Sellers, James R.; Gelfand, Vladimir, I

Perfringolysin O-Induced Plasma Membrane Pores Trigger Actomyosin Remodeling and Endoplasmic Reticulum Redistribution

TOXINS

IF4

2019-07-17

OAAI

Brito, Claudia; Mesquita, Francisco S.; Bleck, Christopher K. E.; Sellers, James R.; Cabanes, Didier; Sousa, Sandra