Adelina Orellana

ACE Alzheimer Center Barcelona

H指数:35

被引数:9,414

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A single-center open-label, randomized, parallel-group controlled clinical trial on the long-term effect of the treatment with EGb 761 in blood markers of inflammation and neurodegeneration in patients with mild cognitive impairment: ACE-2020-EGb 761

单中心开放标签、随机、平行组对照临床试验，研究EGb 761治疗对轻度认知障碍患者炎症和神经退行性变血液标志物的长期效果：ACE-2020-EGb 761

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2026-09-290

PRE

Xavier Morato; Marta Marquié; Juan Pablo Tartari; Asunción Lafuente; María Eugenia Sáez; Laia Montoliu-Gaya; Hanna Huber; Montserrat Alegret; Sara Jofresa; Mar Buendía; Ana Pancho; Nuria Aguilera; Marta Ibarria; Susana Diego; Rosario Cuevas; Laia Cañada; Alba Pérez-Cordón; Angela Sanabria; Itziar De Rojas; Amanda Cano; Adelina Orellana; Laura Montrreal; Maitee Rosende-Roca; Liliana Vargas; Ana Espinosa; Gemma Ortega; Raúl Núñez-Llaves; Marta Martínez-Lucas; Yahveth Cantero-Fortiz; Emilio Alarcón-Martín; Miren Gurruchaga; Lluís Tárraga; Sergi Valero; Pilar Sanz-Cartagena; Santos Mañes; Henrik Zetterberg; Agustín Ruiz; Mercè Boada

Validation of human kallikrein 6 in the cerebrospinal fluid of patients with progressive and non-progressive alzheimer’s disease: correlation with other biomarkers

人类激肽释放酶6在进展性和非进展性阿尔茨海默病患者脑脊液中的验证：与其他生物标志物的相关性

Clinical Proteomics

IF3.3

2026-03-150

OAAI

A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

一种微创的干血斑生物标志物检测方法，用于检测阿尔茨海默病的病理学

Nature Medicine

IF50

2026-01-050

OAAI

Hanna Huber; Laia Montoliu-Gaya; Wagner S. Brum; Jakub Vávra; Yara Yakoub; Haley Weninger; Luisa Sophie Braun-Wohlfahrt; Joel Simrén; Mercé Boada; Agustín Ruiz; Amanda Cano; Adelina Orellana; Sergi Valero; Laia Cañada; Natalia Tantinya; Ana Belen Nogales; Pilar Sanz-Cartagena; Anna Dittrich; Ingmar Skoog; Millie Sander-Long; Clive Ballard; Megan Richards; Mary O’Leary; Frederikke Kragh Clemmensen; Hannah H. D. Wandall; Daniele Altomare; Valentina Cantoni; Erik Stomrud; Sebastian Palmqvist; Alberto Lleo; Daniel Alcolea; Maria Carmona Iragui; Aida Sanjuan Hernandez; Bessy Benejam; Laura Videla Toro; Alpana Singh; Marisa N. Denkinger; Anja Hviid Simonsen; Silke Kern; Anne Corbett; Juan Fortea; Lee Honigberg; Barbara Borroni; Oskar Hansson; Xavier Morató; Kaj Blennow; Henrik Zetterberg; Nicholas J. Ashton

Associations of lifestyle factors with amyloid pathology in persons without dementia

生活方式因素与无痴呆人群淀粉样蛋白病理的相关性

Journal of Alzheimer’s Disease

IF0

2025-11-130

Julie E Oomens; Stephanie JB Vos; Nancy N Maserejian; Mercè Boada; Mira Didic; Sebastiaan Engelborghs; Tormod Fladby; Wiesje M van der Flier; Giovanni B Frisoni; Lutz Fröhlich; Kiran Dip Gill; Timo Grimmer; Jakub Hort; Yoshiaki Itoh; Takeshi Iwatsubo; Aleksandra Klimkowicz-Mrowiec; Susan M Landau; Dong Young Lee; Alberto Lleó; Pablo Martinez-Lage; Alexandre de Mendonça; Philipp T Meyer; Piero Parchi; Matteo Pardini; Lucilla Parnetti; Julius Popp; Lorena Rami; Eric M Reiman; Juha O Rinne; Karen M Rodrigue; Pascual Sánchez-Juan; Isabel Santana; Nikolaos Scarmeas; Philip Scheltens; Ingmar Skoog; Reisa A Sperling; Yaakov Stern; Sylvia Villeneuve; Gunhild Waldemar; Jens Wiltfang; Henrik Zetterberg; Daniel Alcolea; Ricardo F Allegri; Daniele Altomare; Randall J Bateman; Simone Baiardi; Ines Baldeiras; Kaj Blennow; Anouk den Braber; Mark A van Buchem; Min Soo Byun; Jiří Cerman; Kewei Chen; Elena Chipi; Gregory S Day; Alexander Drzezga; Laura L Ekblad; Stefan Förster; Juan Fortea; Yvonne Freund-Levi; Lars Frings; Eric Guedj; Christian G Habeck; Ron Handels; Lucrezia Hausner; Sabine Hellwig; Julio F Jiménez-Bonilla; Ane Iriondo Juaristi; Ramesh Kandimalla; Silke Kern; Bjørn-Eivind S Bordewick Kirsebom; Johannes Kornhuber; Nienke Legdeur; Johannes Levin; Wolfgang Maier; Marta Marquié; Shinobu Minatani; Silvia Daniela Morbelli; Barbara Mroczko; Eva Ntanasi; Catarina Resende de Oliveira; Adelina Orellana; Oliver Peters; Sudesh Prabhakar; Inez H Ramakers; Eloy Rodríguez-Rodriguez; Agustín Ruiz; Eckart Rüther; Jayant Sakhardande; Per Selnes; Dina Silva; Hilkka Soininen; Luiza Spiru; Akitoshi Takeda; Charlotte E Teunissen; Betty M Tijms; Lisa Vermunt; Åsa K Wallin; Wietse Wiels; Mary Yannakoulia; Dahyun Yi; Anna Zettergren; Rik Ossenkoppele; Frans RJ Verhey; Pieter Jelle Visser; Willemijn J Jansen

Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration

认知正常个体脑脊液蛋白质组学特征可识别与神经退行性变相关的不同集群

Nature Aging

IF19.4

2025-10-140

PRE

Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO

FUNCTIONAL & INTEGRATIVE GENOMICS

IF3.1

2025-03-250

OAAI

Puerta, Raquel; de Rojas, Itziar; Garcia-Gonzalez, Pablo; Olive, Claudia; Sotolongo-Grau, Oscar; Garcia-Sanchez, Ainhoa; Garcia-Gutierrez, Fernando; Montrreal, Laura; Tartari, Juan Pablo; Sanabria, Angela; Pytel, Vanesa; Lage, Carmen; Quintela, Ines; Aguilera, Nuria; Rodriguez-Rodriguez, Eloy; Alarcon-Martin, Emilio; Orellana, Adelina; Pastor, Pau; Perez-Tur, Jordi; Pinol-Ripoll, Gerard; de Munain, Adolfo Lopez; Garcia-Alberca, Jose Maria; Royo, Jose Luis; Bullido, Maria J.; Alvarez, Victoria; Real, Luis Miguel; Anchuelo, Arturo Corbaton; Gomez-Garre, Dulcenombre; Larrad, Maria Teresa Martinez; Franco-Macias, Emilio; Mir, Pablo; Medina, Miguel; Sanchez-Valle, Raquel; Dols-Icardo, Oriol; Saez, Maria Eugenia; Carracedo, Angel; Tarraga, Lluis; Alegret, Montse; Valero, Sergi; Marquie, Marta; Boada, Merce; Juan, Pascual Sanchez; Cavazos, Jose Enrique; Cabrera-Socorro, Alfredo; Cano, Amanda; Ruiz, Agustin; Alzheimers Dis Neuroimaging Initiative

Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia

brain behavior and immunity

IF3.5

2024-12-010

OAAI

Amyloid deposition in adults with drug-resistant temporal lobe epilepsy

EPILEPSIA

IF6.6

2024-10-150

PRE

Clinical value of plasma pTau181 to predict Alzheimer's ' s disease pathology in a large real-world cohort of a memory clinic

血浆pTau181在记忆诊所大型真实队列中预测阿尔茨海默病病理的临床价值

EBIOMEDICINE

IF10.8

2024-10-010

OAAI

Cano, Amanda; Capdevila, Maria; Puerta, Raquel; Arranz, Javier; Montrreal, Laura; de Rojas, Itziar; Garcia-Gonzalez, Pablo; Olive, Claudia; Garcia-Gutierrez, Fernando; Sotolongo-Grau, Oscar; Orellana, Adelina; Aguilera, Nuria; Ramis, Maribel; Rosende-Roca, Maitee; Lleo, Alberto; Fortea, Juan; Tartari, Juan Pablo; Lafuente, Asuncion; Vargas, Liliana; Perez-Cordon, Alba; Munoz, Nathalia; Sanabria, Angela; Alegret, Montserrat; Morato, Xavier; Tarraga, Lluis; Fernandez, Victoria; Marquie, Marta; Valero, Sergi; Alcolea, Daniel; Boada, Merce; Ruiz, Agustin

Association of oxidative stress and inflammatory metabolites with Alzheimer's disease cerebrospinal fluid biomarkers in mild cognitive impairment

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2024-07-302

OAAI

An Insertion Within SIRPβ1 Shows a Dual Effect Over Alzheimer's Disease Cognitive Decline Altering the Microglial Response

SIRPβ1内的插入显示出对阿尔茨海默氏病认知下降的双重作用，改变了小胶质细胞的反应

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-03-191

PRE

Garcia-Alberca, Jose Maria; de Rojas, Itziar; Sanchez-Mejias, Elisabeth; Garrido-Martin, Diego; Gonzalez-Palma, Laura; Jimenez, Sebastian; Pino-Angeles, Almudena; Cruz-Gamero, Jose Manuel; Mendoza, Silvia; Alarcon-Martin, Emilio; Munoz-Castro, Clara; Miguel Real, Luis; Jesus Tenao, Juan; Polvillo, Rocio; Govantes, Fernando; Lopez, Aroa; Royo-Aguado, Jose Luis; Navarro, Victoria; Gonzalez, Irene; Ruiz, Maximiliano; Reyes-Engel, Armando; Gris, Esther; Jose Bravo, Maria; Lopez-Gutierrez, Lidia; Mejias-Ortega, Marina; De la Guia, Paz; Lopez de la Rica, Maria; Ocejo, Olga; Torrecilla, Javier; Zafra, Carmen; Dolores Nieto, Maria; Urbano, Concepcion; Jimenez-Sanchez, Rocio; Pareja, Nuria; Luque, Macarena; Garcia-Peralta, Maria; Carrillejo, Rosario; del Carmen Furniet, Maria; Rueda, Lourdes; Sanchez-Fernandez, Ana; Mancilla, Tomas; Pena, Isabel; Garcia-Casares, Natalia; Moreno-Grau, Sonia; Hernandez, Isabel; Montrreal, Laura; Quintela, Ines; Gonzalez-Perez, Antonio; Calero, Miguel; Franco-Macias, Emilio; Macias, Juan; Menendez-Gonzalez, Manuel; Frank-Garcia, Ana; Huerto Vilas, Raquel; Diez-Fairen, Monica; Lage, Carmen; Garcia-Madrona, Sebastian; Garcia-Gonzalez, Pablo; Valero, Sergi; Sotolongo-Grau, Oscar; Perez-Cordon, Alba; Rabano, Alberto; Arias Pastor, Alfonso; Belen Pastor, Ana; Espinosa, Ana; Corma-Gomezn, Anais; Martin Montes, Angel; Sanabria, Angela; Martinez Rodriguez, Carmen; Buiza-Rueda, Dolores; Rodriguez-Rodriguez, Eloy; Ortega, Gemma; Alvarez, Ignacio; Rosas Allende, Irene; Pineda, Juan A.; Rosende-Roca, Maitee; Sanchez-Arjona, Maria Bernal; Fernandez-Fuertes, Marta; Alegret, Montserrat; Roberto, Natalia; del Ser, Teodoro; Garcia-Ribas, Guillermo; Sanchez-Juan, Pascual; Pastor, Pau; Pinol-Ripoll, Gerard; Jose Bullido, Maria; Alvarez, Victoria; Mir, Pablo; Medina, Miguel; Marquie, Marta; Eugenia Saez, Maria; Carracedo, Angel; Laplana, Marina; Tomas-Gallardo, Laura; Orellana, Adelina; Tarraga, Lluis; Boada, Merce; Fibla Palazon, Joan; Vitorica, Javier; Ruiz, Agustin; Guigo, Roderic; Gutierrez, Antonia; Luis Royo, Jose

Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots-A new collectionmethod for remote settings

ALZHEIMERS & DEMENTIA

IF11.1

2024-01-2911

OAAI

Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

MOLECULAR PSYCHIATRY

IF10.1

2024-01-123

OAAI

Hayek, Dayana; Ziegler, Gabriel; Kleineidam, Luca; Brosseron, Frederic; Nemali, Aditya; Vockert, Niklas; Ravichandran, Kishore A.; Betts, Matthew J.; Peters, Oliver; Schneider, Luisa-Sophie; Wang, Xiao; Priller, Josef; Altenstein, Slawek; Schneider, Anja; Fliessbach, Klaus; Wiltfang, Jens; Bartels, Claudia; Rostamzadeh, Ayda; Glanz, Wenzel; Buerger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris-Stephan; Teipel, Stefan; Kilimann, Ingo; Laske, Christoph; Mengel, David; Synofzik, Matthis; Munk, Matthias H.; Spottke, Annika; Roy, Nina; Roeske, Sandra; Kuhn, Elizabeth; Ramirez, Alfredo; Dobisch, Laura; Schmid, Matthias; Berger, Moritz; Wolfsgruber, Steffen; Yakupov, Renat; Hetzer, Stefan; Dechent, Peter; Ewers, Michael; Scheffler, Klaus; Schott, Bjoern H.; Schreiber, Stefanie; Orellana, Adelina; de Rojas, Itziar; Marquie, Marta; Boada, Merce; Sotolongo, Oscar; Gonzalez, Pablo Garcia; Puerta, Raquel; Duezel, Emrah; Jessen, Frank; Wagner, Michael; Ruiz, Augustin; Heneka, Michael T.; Maass, Anne

Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease

MOLECULAR NEURODEGENERATION

IF17.5

2024-01-0311

OAAI

Wang, Lihua; Nykaenen, Niko-Petteri; Western, Daniel; Gorijala, Priyanka; Timsina, Jigyasha; Li, Fuhai; Wang, Zhaohua; Ali, Muhammad; Yang, Chengran; Liu, Menghan; Brock, William; Marquie, Marta; Boada, Merce; Alvarez, Ignacio; Aguilar, Miquel; Pastor, Pau; Ruiz, Agustin; Puerta, Raquel; Orellana, Adelina; Rutledge, Jarod; Oh, Hamilton; Greicius, Michael D.; Le Guen, Yann; Perrin, Richard J.; Wyss-Coray, Tony; Jefferson, Angela; Hohman, Timothy J.; Graff-Radford, Neill; Mori, Hiroshi; Goate, Alison; Levin, Johannes; Sung, Yun Ju; Cruchaga, Carlos

Harnessing acoustic speech parameters to decipher amyloid status in individuals with mild cognitive impairment

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-09-076

OAAI

A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

SCIENTIFIC REPORTS

IF3.9

2023-04-0312

OAAI

Morato, Xavier; Marquie, Marta; Tartari, Juan Pablo; Lafuente, Asuncion; Abdelnour, Carla; Alegret, Montserrat; Jofresa, Sara; Buendia, Mar; Pancho, Ana; Aguilera, Nuria; Ibarria, Marta; Diego, Susana; Cuevas, Rosario; Canada, Laia; Calvet, Anna; Esteban-De Antonio, Ester; Perez-Cordon, Alba; Sanabria, Angela; de Rojas, Itziar; Nunez-Llaves, Raul; Cano, Amanda; Orellana, Adelina; Montrreal, Laura; Canabate, Pilar; Rosende-Roca, Maitee; Vargas, Liliana; Bojaryn, Urszula; Ricciardi, Mario; Ariton, Diana M.; Espinosa, Ana; Ortega, Gemma; Munoz, Nathalia; Lleonart, Nuria; Alarcon-Martin, Emilio; Moreno, Mariola; Preckler, Silvia; Tantinya, Natalia; Ramis, Maribel; Nogales, Ana Belen; Seguer, Susanna; Martin, Elvira; Pytel, Vanesa; Valero, Sergi; Gurruchaga, Miren; Tarraga, Lluis; Ruiz, Agustin; Boada, Merce

Macular vessel density in the superficial plexus is not associated to cerebrospinal fluid core biomarkers for Alzheimer's disease in individuals with mild cognitive impairment: The NORFACE cohort

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-02-235

OAAI

Marquie, Marta; Garcia-Sanchez, Ainhoa; Alarcon-Martin, Emilio; Martinez, Joan; Castilla-Marti, Miguel; Castilla-Marti, Luis; Orellana, Adelina; Montrreal, Laura; de Rojas, Itziar; Garcia-Gonzalez, Pablo; Puerta, Raquel; Olive, Claudia; Cano, Amanda; Hernandez, Isabel; Rosende-Roca, Maitee; Vargas, Liliana; Pablo Tartari, Juan; Esteban-De Antonio, Ester; Bojaryn, Urszula; Ricciardi, Mario; Ariton, Diana M.; Pytel, Vanesa; Alegret, Montserrat; Ortega, Gemma; Espinosa, Ana; Perez-Cordon, Alba; Sanabria, Angela; Munoz, Nathalia; Lleonart, Nuria; Aguilera, Nuria; Tarraga, Lluis; Valero, Sergi; Ruiz, Agustin; Boada, Merce

The Synergic Effect of AT(N) Profiles and Depression on the Risk of Conversion to Dementia in Patients with Mild Cognitive Impairment

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2023-01-106

OAAI

Marquie, Marta; Garcia-Gutierrez, Fernando; Orellana, Adelina; Montrreal, Laura; de Rojas, Itziar; Garcia-Gonzalez, Pablo; Puerta, Raquel; Olive, Claudia; Cano, Amanda; Hernandez, Isabel; Rosende-Roca, Maitee; Vargas, Liliana; Tartari, Juan Pablo; Esteban-De Antonio, Ester; Bojaryn, Urszula; Ricciardi, Mario; Ariton, Diana M.; Pytel, Vanesa; Alegret, Montserrat; Ortega, Gemma; Espinosa, Ana; Perez-Cordon, Alba; Sanabria, Angela; Munoz, Nathalia; Lleonart, Nuria; Aguilera, Nuria; Garcia-Sanchez, Ainhoa; Alarcon-Martin, Emilio; Tarraga, Lluis; Ruiz, Agustin; Boada, Merce; Valero, Sergi

Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers

ACTA NEUROPATHOLOGICA

IF9.3

2022-09-0649

OAAI

Jansen, Ris E.; van der Lee, Sven J.; Gomez-Fonseca, Duber; de Rojas, Itziar; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Zettergren, Anna; Mishra, Aniket; Ali, Muhammad; Andrade, Victor; Bellenguez, Celine; Kleineidam, Luca; Kucukali, Fahri; Sung, Yun Ju; Tesi, Niccolo; Vromen, Ellen M.; Wightman, Douglas P.; Alcolea, Daniel; Alegret, Montserrat; Alvarez, Ignacio; Amouyel, Philippe; Athanasiu, Lavinia; Bahrami, Shahram; Bailly, Henri; Belbin, Olivia; Bergh, Sverre; Bertram, Lars; Biessels, Geert Jan; Blennow, Kaj; Blesa, Rafael; Boada, Merce; Boland, Anne; Buerger, Katharina; Carracedo, Angel; Cervera-Carles, Laura; Chene, Genevieve; Claassen, Jurgen A. H. R.; Debette, Stephanie; Deleuze, Jean-Francois; de Deyn, Peter Paul; Diehl-Schmid, Janine; Djurovic, Srdjan; Dols-Icardo, Oriol; Dufouil, Carole; Duron, Emmanuelle; Duezel, Emrah; Fladby, Tormod; Fortea, Juan; Froelich, Lutz; Garcia-Gonzalez, Pablo; Garcia-Martinez, Maria; Giegling, Ina; Goldhardt, Oliver; Gobom, Johan; Grimmer, Timo; Haapasalo, Annakaisa; Hampel, Harald; Hanon, Olivier; Hausner, Lucrezia; Heilmann-Heimbach, Stefanie; Helisalmi, Seppo; Heneka, Michael T.; Hernandez, Isabel; Herukka, Sanna-Kaisa; Holstege, Henne; Jarholm, Jonas; Kern, Silke; Knapskog, Anne-Brita; Koivisto, Anne M.; Kornhuber, Johannes; Kuulasmaa, Teemu; Lage, Carmen; Laske, Christoph; Leinonen, Ville; Lewczuk, Piotr; Lleo, Alberto; de Munain, Adolfo Lopez; Lopez-Garcia, Sara; Maier, Wolfgang; Marquie, Marta; Mol, Merel O.; Montrreal, Laura; Moreno, Fermin; Moreno-Grau, Sonia; Nicolas, Gael; Nothen, Markus M.; Orellana, Adelina; Palhaugen, Lene; Papma, Janne M.; Pasquier, Florence; Perneczky, Robert; Peters, Oliver; Pijnenburg, Yolande A. L.; Popp, Julius; Posthuma, Danielle; Pozueta, Ana; Priller, Josef; Puerta, Raquel; Quintela, Ines; Ramakers, Inez; Rodriguez-Rodriguez, Eloy; Rujescu, Dan; Saltvedt, Ingvild; Sanchez-Juan, Pascual; Scheltens, Philip; Scherbaum, Norbert; Schmid, Matthias; Schneider, Anja; Selbaek, Geir; Selnes, Per; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tarraga, Lluis; Teipel, Stefan; Tijms, Betty; Tsolaki, Magda; Van Broeckhoven, Christine; Van Dongen, Jasper; van Swieten, John C.; Vandenberghe, Rik; Vidal, Jean-Sebastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M. J.; Zetterberg, Henrik; Zulaica, Miren; van Duijn, Cornelia M.; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Andreassen, Ole A.; Clarimon, Jordi; Sleegers, Kristel; Ruiz, Agustin; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles; van der Flier, Wiesje

A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET Imaging

一种基于PET成像验证的实用，数据驱动的方法来确定阿尔茨海默病CSF生物标志物的临界值

NEUROLOGY

IF8.5

2022-08-168

OAAI

Adelina Orellana

个人简介

教育背景

工作经历

荣誉奖项

研究方向