Iiris Hovatta

university of helsinki

H指数:53

被引数:1.5万

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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

122,341例欧洲血统病例中主要焦虑疾病的全基因组关联研究确定了58个基因座并突出了gaba能信号传导

Nature Genetics

IF29

2026-02-030

OAAI

Nora I. Strom; Brad Verhulst; Silviu-Alin Bacanu; Rosa Cheesman; Kirstin L. Purves; Hüseyin Gedik; Brittany L. Mitchell; Alex S. Kwong; Annika B. Faucon; Kritika Singh; Sarah Medland; Lucia Colodro-Conde; Kristi Krebs; Per Hoffmann; Stefan Herms; Jan Gehlen; Stephan Ripke; Swapnil Awasthi; Teemu Palviainen; Elisa M. Tasanko; Roseann E. Peterson; Daniel E. Adkins; Andrey A. Shabalin; Mark J. Adams; Matthew H. Iveson; Archie Campbell; Laurent F. Thomas; Bendik S. Winsvold; Ole Kristian Drange; Sigrid Børte; Abigail R. ter Kuile; Joonas Naamanka; Tan-Hoang Nguyen; Sandra M. Meier; Elizabeth C. Corfield; Laurie Hannigan; Daniel F. Levey; Darina Czamara; Heike Weber; Karmel W. Choi; Giorgio Pistis; Baptiste Couvy-Duchesne; Sandra Van der Auwera; Alexander Teumer; Robert Karlsson; Miguel Garcia-Argibay; Donghyung Lee; Rujia Wang; Ottar Bjerkeset; Eystein Stordal; Julia Bäckman; Giovanni A. Salum; Clement C. Zai; James L. Kennedy; Gwyneth Zai; Arun K. Tiwari; Stefanie Heilmann-Heimbach; Börge Schmidt; Jaakko Kaprio; Martin M. Kennedy; Joseph Boden; Alexandra Havdahl; Christel M. Middeldorp; Fabiana L. Lopes; Nirmala Akula; Francis J. McMahon; Elisabeth B. Binder; Lydia Fehm; Andreas Ströhle; Enrique Castelao; Henning Tiemeier; Dan J. Stein; David Whiteman; Catherine Olsen; Zachary Fuller; Xin Wang; Naomi R. Wray; Enda M. Byrne; Glyn Lewis; Nicholas J. Timpson; Lea K. Davis; Ian B. Hickie; Nathan A. Gillespie; Lili Milani; Johannes Schumacher; David P. Woldbye; Andreas J. Forstner; Markus M. Nöthen; Iiris Hovatta; John Horwood; William E. Copeland; Hermine H. Maes; Andrew M. McIntosh; Ole A. Andreassen; John-Anker Zwart; Ole Mors; Anders D. Børglum; Preben B. Mortensen; Helga Ask; Ted Reichborn-Kjennerud; Jackob M. Najman; Murray B. Stein; Joel Gelernter; Yuri Milaneschi; Brenda W. Penninx; Dorret I. Boomsma; Eduard Maron; Angelika Erhardt-Lehmann; Christian Rück; Tilo T. Kircher; Christiane A. Melzig; Georg W. Alpers; Volker Arolt; Katharina Domschke; Jordan W. Smoller; Martin Preisig; Nicholas G. Martin; Michelle K. Lupton; Annemarie I. Luik; Andreas Reif; Hans J. Grabe; Henrik Larsson; Patrik K. Magnusson; Albertine J. Oldehinkel; Catharina A. Hartman; Gerome Breen; Anna R. Docherty; Hilary Coon; Rupert Conrad; Kelli Lehto; Jürgen Deckert; Thalia C. Eley; Manuel Mattheisen; John M. Hettema

Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression

全基因组关联分析识别出早发型和晚发型抑郁症不同的遗传结构

Nature Genetics

IF29

2025-11-130

OAAI

John R. Shorter; Joëlle A. Pasman; Siim Kurvits; Andreas Jangmo; Joonas Naamanka; Arvid Harder; Espen Hagen; Kaarina Kowalec; Nelli Frilander; Richard Zetterberg; Joeri J. Meijsen; Jesper R. Gådin; Jacob Bergstedt; Ying Xiong; Sara Hägg; Mikael Landén; Christian Rück; John Wallert; Alkistis Skalkidou; Elise Koch; Bayram C. Akdeniz; Oleksandr Frei; Iiris Hovatta; Ted Reichborn-Kjennerud; Thomas M. Werge; Patrick F. Sullivan; Ole A. Andreassen; Martin Tesli; Kelli Lehto; Alfonso Buil; Yi Lu

Predicting cardiovascular morbidity and mortality with SCORE2 (OP) and Framingham risk estimates in combination with indicators of biological ageing

使用SCORE2 (OP)和Framingham风险评分，结合生物学衰老指标预测心血管疾病发病率和死亡率

AGE AND AGEING

IF7.1

2025-04-030

PRE

Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease

与冠状动脉疾病相比，主动脉瓣狭窄的遗传风险特征不同

JAMA CARDIOLOGY

IF14.1

2025-02-011

PRE

Trenkwalder, Teresa; Maj, Carlo; Al-Kassou, Baravan; Debiec, Radoslaw; Doppler, Stefanie A.; Musameh, Muntaser D.; Nelson, Christopher P.; Dasmeh, Pouria; Grover, Sandeep; Knoll, Katharina; Naamanka, Joonas; Mordi, Ify R.; Braund, Peter S.; Dressen, Martina; Lahm, Harald; Wirth, Felix; Baldus, Stephan; Kelm, Malte; von Scheidt, Moritz; Krefting, Johannes; Ellinghaus, David; Small, Aeron M.; Peloso, Gina M.; Natarajan, Pradeep; Thanassoulis, George; Engert, James C.; Dufresne, Line; Franke, Andre; Goerg, Siegfried; Laudes, Matthias; Nowak-Goettl, Ulrike; Vaht, Mariliis; Metspalu, Andres; Stoll, Monika; Berger, Klaus; Pellegrini, Costanza; Kastrati, Adnan; Hengstenberg, Christian; Lang, Chim C.; Kessler, Thorsten; Hovatta, Iiris; Nickenig, Georg; Noethen, Markus M.; Krane, Markus; Schunkert, Heribert; Samani, Nilesh J.; Schumacher, Johannes

Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes

携带APP瑞典突变的人iPSC衍生的周细胞样细胞过度产生 β-淀粉样蛋白并诱导脑淀粉样血管病样变化

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2024-09-270

OAAI

The effect of REM-sleep disruption on affective processing: A systematic review of human and animal experimental studies

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

IF7.9

2024-07-010

OAAI

Genetic contribution to microglial activation in schizophrenia

精神分裂症小胶质细胞激活的遗传贡献

MOLECULAR PSYCHIATRY

IF10.1

2024-03-226

OAAI

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

抑郁症病理生理学，使用全基因组分析的复发和共病精神疾病的风险预测

NATURE MEDICINE

IF50

2023-07-1862

Als, Thomas D. D.; Kurki, Mitja I. I.; Grove, Jakob; Voloudakis, Georgios; Therrien, Karen; Tasanko, Elisa; Nielsen, Trine Tollerup; Naamanka, Joonas; Veerapen, Kumar; Levey, Daniel F. F.; Bendl, Jaroslav; Bybjerg-Grauholm, Jonas; Zeng, Biao; Demontis, Ditte; Rosengren, Anders; Athanasiadis, Georgios; Baekved-Hansen, Marie; Qvist, Per; Walters, G. Bragi; Thorgeirsson, Thorgeir; Stefansson, Hreinn; Musliner, Katherine L. L.; Rajagopal, Veera M. M.; Farajzadeh, Leila; Thirstrup, Janne; Vilhjalmsson, Bjarni J. J.; McGrath, John J. J.; Mattheisen, Manuel; Meier, Sandra; Agerbo, Esben; Stefansson, Kari; Nordentoft, Merete; Werge, Thomas; Hougaard, David M. M.; Mortensen, Preben B. B.; Stein, Murray B. B.; Gelernter, Joel; Hovatta, Iiris; Roussos, Panos; Daly, Mark J. J.; Mors, Ole; Palotie, Aarno; Borglum, Anders D. D.

Childhood adversities are associated with shorter leukocyte telomere length at adult age in a population-based study (vol 130, 105276, 2021)

PSYCHONEUROENDOCRINOLOGY

IF3.6

2023-07-010

OAAI

Genetic insights into the neurobiology of anxiety

TRENDS IN NEUROSCIENCES

IF15.1

2023-04-0112

Node of Ranvier remodeling in chronic psychosocial stress and anxiety

NEUROPSYCHOPHARMACOLOGY

IF7.1

2023-03-226

OAAI

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice

CELLS

IF5.2

2022-12-182

OAAI

GENOME-WIDE ANALYSIS IDENTIFIES SORCS3 AS A NOVEL SUSCEPTIBILITY LOCUS FOR PANIC DISORDER IN THE FINNGEN STUDY

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2022-10-010

PRE

Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia

GLIA

IF5.1

2021-12-2214

OAAI

Koskuvi, Marja; Lehtonen, Sarka; Trontti, Kalevi; Keuters, Meike; Wu, Ying-Chieh; Koivisto, Hennariikka; Ludwig, Anastasia; Plotnikova, Lidiia; Virtanen, Pekka L. J.; Rasanen, Noora; Kaipainen, Satu; Hyotylainen, Ida; Dhungana, Hiramani; Giniatullina, Raisa; Ojansuu, Ilkka; Vaurio, Olli; Cannon, Tyrone D.; Lonnqvist, Jouko; Therman, Sebastian; Suvisaari, Jaana; Kaprio, Jaakko; Lahteenvuo, Markku; Tohka, Jussi; Giniatullin, Rashid; Rivera, Claudio; Hovatta, Iiris; Tanila, Heikki; Tiihonen, Jari; Koistinaho, Jari

miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine

NEUROBIOLOGY OF STRESS

IF3.6

2021-11-0128

OAAI

Childhood adversities are associated with shorter leukocyte telomere length at adult age in a population-based study

在一项基于人群的研究中，儿童时期的逆境与成年时较短的白细胞端粒长度有关

PSYCHONEUROENDOCRINOLOGY

IF3.6

2021-08-018

OAAI

Peripheral metabolic state and immune system in first-episode psychosis ? A gene expression study with a prospective one-year follow-up