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B

Beate Hagl

University of Augsburg
H指数:13
被引数:851

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Signal Transducer and Activator of Transcription 3 (STAT3) Variant p.K709N Causes Hyper-IgE Syndrome Likely by Impaired STAT3-Dimer Formation

信号转导子和转录激活因子3（STAT3）变体p.K709N导致高IgE综合征，可能通过抑制STAT3二聚体形成。

European Journal of Immunology
IF3.7
2025-07-280
OAAI
Beate Hagl; Benedikt D. Spielberger; Betina Neumann; Simon J. Pelham; Dharmendra Pandey; Andreas Schlundt; Camille Barro; Anica Lechner; Christine Wolf; Elissa K. Deenick; Michael Sattler; Stuart G. Tangye; Simon Rothenfusser; Ellen D. Renner
Rescue of STAT3 Function in Hyper-IgE Syndrome Using Adenine Base Editing
CRISPR JOURNAL
IF4
2021-04-0112
PRE
Eberherr, Andreas C.; Maaske, Andre; Wolf, Christine; Giesert, Florian; Berutti, Riccardo; Rusha, Ejona; Pertek, Anna; Kastlmeier, Miriam T.; Voss, Carola; Plummer, Michelle; Sayed, Amina; Graf, Elisabeth; Effner, Renate; Volz, Thomas; Drukker, Micha; Strom, Tim M.; Meitinger, Thomas; Stoeger, Tobias; Buyx, Alena M.; Hagl, Beate; Renner, Ellen D.
Impaired memory B-cell development and antibody maturation with a skewing toward IgE in patients with STAT3 hyper-IgE syndrome

STAT3高IgE综合征患者记忆b细胞发育和抗体成熟受损，向IgE倾斜

ALLERGY
IF12
2019-08-1633
PREAI
van de Veen, Willem; Kraetz, Carolin E.; McKenzie, Craig I.; Aui, Pei M.; Neumann, Jens; van Noesel, Carel J. M.; Wirz, Oliver F.; Hagl, Beate; Kroener, Carolin; Spielberger, Benedikt D.; Akdis, Cezmi A.; van Zelm, Menno C.; Akdis, Mubeccel; Renner, Ellen D.
Lung disease in STAT3 hyper-IgE syndrome requires intense therapy

STAT3高IgE综合征中的肺部疾病需要强化治疗

ALLERGY
IF12
2019-04-0419
PREAI
Kroener, Carolin; Neumann, Jens; Ley-Zaporozhan, Julia; Hagl, Beate; Meixner, Iris; Spielberger, Benedikt D.; Dueckers, Gregor; Belohradsky, Bernd H.; Niehues, Tim; Borte, Michael; Rosenecker, Joseph; Kappler, Matthias; Naehrig, Susanne; Reu, Simone; Griese, Matthias; Renner, Ellen D.
Key findings to expedite the diagnosis of hyper-IgE syndromes in infants and young children
PEDIATRIC ALLERGY AND IMMUNOLOGY
IF4.5
2016-01-2642
PREAI
Hagl, Beate; Heinz, Valerie; Schlesinger, Anne; Spielberger, Benedikt D.; Sawalle-Belohradsky, Julie; Senn-Rauh, Monika; Magg, Thomas; Boos, Annette C.; Hoenig, Manfred; Schwarz, Klaus; Dueckers, Gregor; von Bernuth, Horst; Pache, Christoph; Karitnig-Weiss, Caecilia; Belohradsky, Bernd H.; Frank, Josef; Niehues, Tim; Wahn, Volker; Albert, Michael H.; Wollenberg, Andreas; Jansson, Annette F.; Renner, Ellen D.
DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2015-01-28225
PREAI
Aydin, Susanne E.; Kilic, Sara Sebnem; Aytekin, Caner; Kumar, Ashish; Porras, Oscar; Kainulainen, Leena; Kostyuchenko, Larysa; Genel, Ferah; Kutukculer, Necil; Karaca, Neslihan; Gonzalez-Granado, Luis; Abbott, Jordan; Al-Zahrani, Daifulah; Rezaei, Nima; Baz, Zeina; Thiel, Jens; Ehl, Stephan; Marodi, Laszlo; Orange, Jordan S.; Sawalle-Belohradsky, Julie; Keles, Sevgi; Holland, Steven M.; Sanal, Ozden; Ayvaz, Deniz C.; Tezcan, Ilhan; Al-Mousa, Hamoud; Alsum, Zobaida; Hawwari, Abbas; Metin, Ayse; Matthes-Martin, Susanne; Hoenig, Manfred; Schulz, Ansgar; Picard, Capucine; Barlogis, Vincent; Gennery, Andrew; Ifversen, Marianne; van Montfrans, Joris; Kuijpers, Taco; Bredius, Robbert; Duckers, Gregor; Al-Herz, Waleed; Pai, Sung-Yun; Geha, Raif; Notheis, Gundula; Schwarze, Carl-Philipp; Tavil, Betul; Azik, Fatih; Bienemann, Kirsten; Grimbacher, Bodo; Heinz, Valerie; Gaspar, H. Bobby; Aydin, Roland; Hagl, Beate; Gathmann, Benjamin; Belohradsky, Bernd H.; Ochs, Hans D.; Chatila, Talal; Renner, Ellen D.; Su, Helen; Freeman, Alexandra F.; Engelhardt, Karin; Albert, Michael H.

研究方向

暂未获取到该数据
E
Ellen D. Renner
H 指数:33论文数:98被引数:7,354
B
Benedikt D. Spielberger
H 指数:10论文数:35被引数:312
J
Julie Sawalle‐Belohradsky
H 指数:11论文数:29被引数:1,671
G
Gregor Dückers
H 指数:21论文数:68被引数:2,532
T
Tim Niehues
H 指数:48论文数:366被引数:1.1万
B
Bernd H. Belohradsky
H 指数:56论文数:213被引数:1.5万
R
Renate Effner
H 指数:8论文数:30被引数:464
A
Andreas Wollenberg
H 指数:79论文数:579被引数:2.8万
J
Jens Neumann
H 指数:43论文数:411被引数:9,272
C
Carolin Kröner
H 指数:13论文数:48被引数:677