Gráinne S. Gorman - Publications, H-index & Citations

Gráinne S. Gorman

newcastle university

52H指数

261论文数

1.0W被引数

收录论文 117

发表时间

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use 线粒体疾病中的数字认知测试：临床试验应用的效度与挑战

Annals of Clinical and Translational Neurology

IF3.9

2026-08-20

OAAI

Oksana Pogoryelova; Jan Smeitink; Herma Renkema; Rosabeth White; Frankie Barton; Rachel Lyon; Jane Newman; Aye Moe; Yi Shiau Ng; Grainne Siobhan Gorman

Skeletal muscle effects of Janus kinase inhibition in rheumatoid arthritis (RAMUS): a single-arm, experimental medicine study 类风湿关节炎中JAK激酶抑制对骨骼肌的影响（RAMUS）：一项单臂实验性药物研究

The Lancet Rheumatology

IF0

2025-10-15

OAAI

Joshua L Bennett; Kieren G Hollingsworth; Arthur G Pratt; Abbie E A Degnan; Gráinne S Gorman; Catherine Feeney; Najib Naamane; Jérémie Nsengimana; Avan A Sayer; Amy E Anderson; John D Isaacs

RePOWER: An International, Prospective, Non-Interventional Registry of Patients With Primary Mitochondrial Myopathy RePOWER：一项国际性、前瞻性、非干预性原发性线粒体肌病患者登记研究

Clinical Genetics

IF2.3

2025-08-11

PREAI

Amel Karaa; Amy Goldstein; Bruce H. Cohen; Richard H. Haas; Jerry Vockley; Gráinne S. Gorman; Michelangelo Mancuso; the RePOWER, MMPOWER-3, and MOTOR investigators

Delineating the mechanisms of cerebellar degeneration in paediatric and adult primary mitochondrial disease 阐述儿童及成人原发性线粒体疾病中小脑退行性变的机制

Acta Neuropathologica

IF9.3

2025-05-30

OAAI

Laura A. Smith; Elizaveta A. Olkhova; Nichola Z. Lax; Yi Shiau Ng; Robert W. Taylor; Grainne S. Gorman; Daniel Erskine; Robert McFarland

Qualitative study of fatigue in adults with primary mitochondrial disease: Development of the PROMIS Fatigue Mitochondrial Disease Short Form 原发性线粒体疾病成人疲劳的定性研究：PROMIS疲劳线粒体疾病简表的开发

Molecular Genetics and Metabolism

IF3.5

2025-05-26

PREAI

Sarah Clifford; Renae J. Stefanetti; Roxana Bahar; Magnus J. Hansson; Gráinne S. Gorman; Amel Karaa

Measurement of Twitch Dynamics in Response to Exercise Induced Changes in Mitochondrial Disease Using Motor Unit Magnetic Resonance Imaging (MUMRI): A Proof-of-Concept Study 使用运动单位磁共振成像（MUMRI）测量运动诱发的线粒体疾病中抽搐动力学的变化：一项概念验证研究

NMR IN BIOMEDICINE

IF2.7

2025-04-09

OAAI

Birkbeck, Matthew G.; Elameer, Mathew; Heskamp, Linda; Newman, Jane; Stefanetti, Renae J.; Barrow, Isabel; Pogoryelova, Oksana; Gorman, Grainne S.; Hall, Julie; Schofield, Ian S.; Blamire, Andrew M.; Whittaker, Roger G.

Effect of acipimox on skeletal muscle biochemistry, structure and function in older people with probable sarcopenia: an experimental medicine study 阿昔莫司对可能患有肌肉减少症的老年人骨骼肌生化，结构和功能的影响: 一项实验医学研究

GEROSCIENCE

IF5.4

2025-03-01

OAAI

Mcdonald, Claire; Alderson, Craig; Birkbeck, Matthew G.; Del Din, Silvia; Gorman, Grainne S.; Hollingsworth, Kieren G.; Kirk, Cameron; Massarella, Clare; Rochester, Lynn; Tuppen, Helen A. L.; Warren, Charlotte; Sayer, Avan A.; Witham, Miles D.

Elevated glioma-related cortical glutamate in vivo is associated with ex vivo interictal discharges in human brain slices 在体升高的胶质瘤相关皮层谷氨酸与离体间期放电在人类脑片中的关联

BRAIN COMMUNICATIONS

IF4.5

2025-01-01

OAAI

Jayasekera, Bodiabaduge Ashan P.; Parikh, Jehill; Modebadze, Tamara; Brito Da Silva, Anderson; Stefanetti, Renae J.; Crossman, John; Holliman, Damian; Hussain, Mohammed A.; Jenkins, Alistair; Major, Otto; Mitchell, Patrick; Nicholson, Claire; Ross, Nicholas; Wallace, Dorothy; Ward, Louise; Hodgson, Tim; Baker, Mark R.; Gorman, Grainne S.; Blamire, Andrew; Cunningham, Mark O.; Cowie, Christopher J. A.; Lebeau, Fiona E. N.

Outcomes misaligned in mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS): implications for trial design 线粒体脑肌病、乳酸酸中毒和卒中样发作（MELAS）中结果的不一致：对试验设计的启示

BRAIN COMMUNICATIONS

IF4.5

2025-01-01

OAAI

Stefanetti, Renae J.; Charman, Sarah J.; Newman, Jane; Hallsworth, Kate; Blain, Alasdair P.; Ng, Yi Shiau; Gorman, Grainne S.

Optimizing rare disorder trials: a phase 1a/1b randomized study of KL1333 in adults with mitochondrial disease

BRAIN

IF11.7

2024-12-09

PREAI

Pizzamiglio, Chiara; Stefanetti, Renae J.; Mcfarland, Robert; Thomas, Naomi; Ransley, George; Hugerth, Matilda; Gronberg, Alvar; Serrano, Sonia Simon; Elmer, Eskil; Hanna, Michael G.; Hansson, Magnus J.; Gorman, Grainne S.; Pitceathly, Robert D. S.

Genotype-specific effects of elamipretide in patients with primary mitochondrial myopathy: a post hoc analysis of the MMPOWER-3 trial

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2024-11-21

OAAI

Karaa, Amel; Bertini, Enrico; Carelli, Valerio; Cohen, Bruce; Ennes, Gregory M.; Falk, Marni J.; Goldstein, Amy; Gorman, Grainne; Haas, Richard; Hirano, Michio; Klopstock, Thomas; Koenig, Mary Kay; Kornblum, Cornelia; Lamperti, Costanza; Lehman, Anna; Longo, Nicola; Molnar, Maria Judit; Parikh, Sumit; Phan, Han; Pitceathly, Robert D. S.; Saneto, Russekk; Scaglia, Fernando; Servidei, Serenella; Tarnopolsky, Mark; Toscano, Antonio; Van Hove, Johan L. K.; Vissing, John; Vockley, Jerry; Finman, Jeffrey S.; Abbruscato, Anthony; Brown, David A.; Sullivan, Alana; Shiffer, James A.; Mancuso, Michelango

Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation 2b期sonlicromanol项目，用于m.3243A>G突变所致线粒体疾病患者

BRAIN

IF11.7

2024-11-06

OAAI

Smeitink, Jan; van Es, Just; Bosman, Brigitte; Janssen, Mirian C. H.; Klopstock, Thomas; Gorman, Grainne; Vissing, John; Ruiterkamp, Gerrit; Edgar, Chris J.; Abbink, Evertine J.; van Maanen, Rob; Pogoryelova, Oksana; Stendel, Claudia; Bischoff, Almut; Karin, Ivan; Munshi, Mahtab; Kummel, Anne; Burgert, Lydia; Verhaak, Christianne; Renkema, Herma

Auditory and vestibular function in mitochondrial patients harbouring the m.3243A>G variant 携带m.3243A>G变体的线粒体患者的听觉和前庭功能

BRAIN COMMUNICATIONS

IF4.5

2024-10-14

OAAI

Stefanetti, Renae J.; Newman, Jane; Blain, Alasdair P.; Chisari, Donella; Gorman, Grainne S.; Rance, Gary

Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2024-04-02

OAAI

Olkhova, Elizaveta A.; Smith, Laura A.; Dennis, Bethany H.; Ng, Yi Shiau; Lebeau, Fiona E. N.; Gorman, Grainne S.

Conformational fingerprinting with Raman spectroscopy reveals protein structure as a translational biomarker of muscle pathology

ANALYST

IF3.3

2024-01-01

OAAI

Alix, James J. P.; Plesia, Maria; Dudgeon, Alexander P.; Kendall, Catherine A.; Hewamadduma, Channa; Hadjivassiliou, Marios; Gorman, Grainne S.; Taylor, Robert W.; McDermott, Christopher J.; Shaw, Pamela J.; Mead, Richard J.; Day, John C.

The West of Scotland Cohort of Mitochondrial Individuals with the m.3243A>G Variant: Variations in Phenotypes and Predictors of Disease Severity 具有m.3243A>G变体的线粒体个体的苏格兰西部队列: 疾病严重程度的表型和预测因子的变化

JOURNAL OF NEUROMUSCULAR DISEASES

IF3.4

2023-12-13

OAAI

Saunders, Charlie; Longman, Cheryl; Gorman, Grainne; James, Kelly; Oliwa, Agata; Petty, Richard; Snadden, Lesley; Farrugia, Maria Elena

Review of mortality data in mitochondrial disease over 12 years

JOURNAL OF THE NEUROLOGICAL SCIENCES

IF3.2

2023-12-01

PREAI

Moe, Aye; Gorman, Grainne; Mcfarland, Robert; Ng, Yi

Biologically derived epicardial patch induces macrophage mediated pathophysiologic repair in chronically infarcted swine hearts

COMMUNICATIONS BIOLOGY

IF5.1

2023-11-25

OAAI

Lancaster, J. J.; Grijalva, A.; Fink, J.; Ref, J.; Daugherty, S.; Whitman, S.; Fox, K.; Gorman, G.; Lancaster, L. D.; Avery, R.; Acharya, T.; Mcarthur, A.; Strom, J.; Pierce, M. K.; Moukabary, T.; Borgstrom, M.; Benson, D.; Mangiola, M.; Pandey, A. C.; Zile, M. R.; Bradshaw, A.; Koevary, J. W.; Goldman, S.

A novel mouse model of mitochondrial disease exhibits juvenile-onset severe neurological impairment due to parvalbumin cell mitochondrial dysfunction

COMMUNICATIONS BIOLOGY

IF5.1

2023-10-23

OAAI

Olkhova, Elizaveta A.; Bradshaw, Carla; Blain, Alasdair; Alvim, Debora; Turnbull, Doug M.; Lebeau, Fiona E. N.; Ng, Yi Shiau; Gorman, Grainne S.; Lax, Nichola Z.

T cell differentiation drives the negative selection of pathogenic mitochondrial DNA variants T细胞分化驱动致病性线粒体DNA变体的负选择

LIFE SCIENCE ALLIANCE

IF2.9

2023-08-31

OAAI

Franklin, Imogen G.; Milne, Paul; Childs, Jordan; Boggan, Roisin M.; Barrow, Isabel; Lawless, Conor; Gorman, Grainne S.; Ng, Yi Shiau; Collin, Matthew; Russell, Oliver M.; Pickett, Sarah J.

研究方向