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收藏Stable Biotherapeutic Penetration Screening in Critically Small Colorectal Metastatic Cancer Biopsies Allows for Oncolytic Virus-Delivered Chemotherapeutic Response Assessment through 3D Bioprinted Organoid Expansion
Mcguckin, Colin; Forraz, Nico; Milet, Clement; Lacroix, Mathieu; Sbirkov, Yordan; Sarafian, Victoria; Ebel, Caroline; Spindler, Anita; Koerper, Veronique; Quemeneur, Eric; Balloul, Jean-Marc; Erbs, Philippe 分享 收藏 3D bioprinted CRC model brings to light the replication necessity of an oncolytic vaccinia virus encoding FCU1 gene to exert an efficient anti-tumoral activityMarquette, Christophe A.; Petiot, Emma; Spindler, Anita; Ebel, Caroline; Nzepa, Mael; Moreau, Baptiste; Erbs, Philippe; Balloul, Jean-Marc; Quemeneur, Eric; Zaupa, Cecile 分享 收藏 Patient-derived tumoroids and proteomic signatures: tools for early drug discoveryLe, Helene; Deforges, Jules; Cutolo, Pasquale; Lamarque, Anissa; Hua, Guoqiang; Lindner, Veronique; Jain, Shreyansh; Balloul, Jean-Marc; Benkirane-Jessel, Nadia; Quemeneur, Eric 分享 收藏 Patient-Derived Tumoroid for the Prediction of Radiotherapy and Chemotherapy Responses in Non-Small-Cell Lung Cancer患者来源的肿瘤样预测非小细胞肺癌的放疗和化疗反应Nounsi, Anasse; Seitlinger, Joseph; Ponte, Charlotte; Demiselle, Julien; Idoux-Gillet, Ysia; Pencreach, Erwan; Beau-Faller, Michele; Lindner, Veronique; Balloul, Jean-Marc; Quemeneur, Eric; Burckel, Helene; Noel, Georges; Olland, Anne; Fioretti, Florence; Falcoz, Pierre-Emmanuel; Benkirane-Jessel, Nadia; Hua, Guoqiang 分享 收藏 Feasibility and immunogenicity of adjuvant TG4050, a patient tailored cancer vaccine in head and neck and ovarian cancerLalanne, Ana; Jamet, Camille; Ottensmeier, Christian H.; Delord, Jean-Pierre; Le Tourneau, Christophe; Block, Matthew S.; Colon-Otero, Gerardo; Knutson, Keith L.; Tavernaro, Annette; Lacoste, Gisele; Grellier, Benoit; Noiriel, Xavier; Huss, Thierry; Burtin, Bernard; Yamashita, Yoshiko; Onoue, Kousuke; Onoguchi, Kazuhide; Malone, Brandon; Lantz, Olivier; Baker, Oliver; Yamagata, Naoko; Tanaka, Yuki; Quemeneur, Eric; Brandely, Maud; Bendjama, Kaidre 分享 收藏 Selection of an optimal anti-PD-L1 single domain antibody format for the vectorization into oncolytic vaccinia virus and the generation of bispecific immunomodulatorsMarchand, Jean-Baptiste; Pintado, Elodie; Dunlop, Marshall; Remy, Christelle; Kleinpeter, Patricia; Shon, Shirley; Laetitia, Fend; Brandely, Renee; Suhner, Delphine; Winter, Eline; Silvestre, Nathalie; Huguet, Claire; Fitzgerald, Peter; Quemeneur, Eric 分享 收藏 TG6050 an oncolytic vaccinia virus armed with interleukin 12 and anti-CTLA4 antibody induces TME remodeling and strong anti-tumoral responsesMarchand, Jean-Baptiste; Azar, Fadi; Demeusoit, Christelle; Kleinpeter, Patricia; Deforges, Jules; Laetitia, Fend; Hoffmann, Chantal; Schultz, Huguette; Silvestre, Nathalie; Quemeneur, Eric 分享 收藏 Extracellular vesicles (EV) - mediators of therapeutic vaccination? In vivo and in vitro characterization of EVs generated after infection of human and murine cells with therapeutic poxvirusesWalther, Lucas; Tosch, Caroline; Deforges, Jules; Carapito, Christine; Rompais, Magali; Claudepierre, Marie-Christine; Silvestre, Nathalie; Bendjama, Kaidre; Quemeneur, Eric; Goetz, Jacky; Hyenne, Vincent; Rittner, Karola 分享 收藏 PoxSTG, a novel chimeric poxvirus with improved oncolytic potencyErbs, Philippe; Findeli, Annie; Foloppe, Johann; Kempf, Juliette; Farine, Isabelle; Moreau, Baptiste; Hortelano, Julie; Pichon, Christelle; Deforges, Jules; Quemeneur, Eric 分享 收藏 分享 收藏 AZD4820 ONCOLYTIC VACCINIA VIRUS ENCODING IL-12 MEDIATES ANTI-TUMOR ACTIVITY THROUGH ONCOLYSIS AND TUMOR-SPECIFIC IMMUNITYKurokawa, Cheyne; Agrawal, Sonia; Mitra, Abhisek; Galvani, Elena; Burke, Shannon; Varshine, Ankita; Rothstein, Raymond; Foloppe, Johann; Silvestre, Nathalie; Quemeneur, Eric; Sapra, Puja; Barrett, Carl; Hammond, Scott; Laliberte, Jason; Durham, Nicholas; Oberst, Michael; Broggi, Maria 分享 收藏 Direct imaging and automatic analysis in tumor-on-chip reveal cooperative antitumoral activity of immune cells and oncolytic vaccinia virusMencattini, Arianna; Lansche, Christine; Veith, Irina; Erbs, Philippe; Balloul, Jean-Marc; Quemeneur, Eric; Descroix, Stephanie; Mechta-Grigoriou, Fatima; Zalcman, Gerard; Zaupa, Cecile; Parrini, Maria Carla; Martinelli, Eugenio 分享 收藏 分享 收藏 Vascularization of Patient-Derived Tumoroid from Non-Small-Cell Lung Cancer and Its MicroenvironmentSeitlinger, Joseph; Nounsi, Anasse; Idoux-Gillet, Ysia; Pujol, Eloy Santos; Le, Helene; Grandgirard, Erwan; Olland, Anne; Lindner, Veronique; Zaupa, Cecile; Balloul, Jean-Marc; Quemeneur, Eric; Massard, Gilbert; Falcoz, Pierre-Emmanuel; Hua, Guoqiang; Benkirane-Jessel, Nadia 分享 收藏 VECTORIZED TREG-DEPLETING ANTI-CTLA-4 ELICITS ANTIGEN CROSS-PRESENTATION AND CD8+T CELL IMMUNITY TO REJECT COLD TUMORSSemmrich, Monika; Marchand, Jean-Baptiste; Rehn, Matilda; Fend, Laetitia; Remy-Ziller, Christelle; Holmkvist, Petra; Silvestre, Nathalie; Svensson, Carolin; Kleinpeter, Patricia; Deforges, Jules; Junghus, Fred; Martensson, Linda; Foloppe, Johann; Teige, Ingrid; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 分享 收藏 Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast CancerBeguin, Jeremy; Foloppe, Johann; Maurey, Christelle; Laloy, Eve; Hortelano, Julie; Nourtier, Virginie; Pichon, Christelle; Cochin, Sandrine; Cordier, Pascale; Huet, Helene; Quemeneur, Eric; Klonjkowski, Bernard; Erbs, Philippe 分享 收藏 Oncolytic vaccinia virus TG6010 expressing cytidine deaminase induces DNA damage and shows potent anti-tumor effectsFoloppe, Johann; Kempf, Juliette; Pichon, Christelle; Findeli, Annie; Farine, Isabelle; Hortelano, Julie; Moreau, Baptiste; Klein, Michele; Cochin, Sandrine; Brandely, Renee; Koerper, Veronique; Silvestre, Nathalie; Machon, Christelle; Guitton, Jerome; Quemeneur, Eric; Erbs, Philippe 分享 收藏 BT-001, an oncolytic vaccinia virus armed with a Treg-depletion-optimized recombinant human anti-CTLA4 antibody and GM-CSF to target the tumor microenvironmentMarchand, Jean-Baptiste; Semmrich, Monika; Fend, Laetitia; Rehn, Matilda; Silvestre, Nathalie; Teige, Ingrid; Foloppe, Johann; Martensson, Linda; Quemeneur, Eric; Frendeus, Bjorn 分享 收藏 
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