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D

Danyel Jennen

Maastricht University
H指数:41
被引数:4,598

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Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety

定量系统毒理学: 建模以机械地理解和预测药物安全性

Nature Reviews Drug Discovery
IF101.8
2025-10-270
PRE
Christopher E. Goldring; Giusy Russomanno; Carmen Pin; Panuwat Trairatphisan; Kylie A. Beattie; Ciarán P. Fisher; Janet Piñero; Richard J. Brennan; Diana Clausznitzer; Ian M. Copple; Theo M. de Kok; Carrie A. Duckworth; Laura I. Furlong; Barbara Füzi; Attila Gabor; Louis Gall; Jan Hengstler; Henning Hermjakob; Fiona Hunter; Danyel Jennen; Mikko Koskinen; Steven J. Kunnen; Lieve Lammens; Sebastian Lobentanzer; Marcel Mohr; Elisa Passini; D. Mark Pritchard; Rahuman S. Malik-Sheriff; Blanca Rodríguez; Eric I. Rossman; Julio Saez-Rodríguez; Friedemann Schmidt; Rowena Sison-Young; Inari Soininen; Sean Turner; Bob van de Water; Johan G. C. van Hasselt; Filippo Venezia; Jeffrey A. Willy; Derek J. Leishman; James L. Stevens; Loic Laplanche
Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer(vol12, 1256, 2022)
NANOMATERIALS
IF4.3
2023-10-310
OAAI
Bischoff, Nicolaj S.; Proquin, Heloise; Jetten, Marlon J.; Schrooders, Yannick; Jonkhout, Marloes C. M.; Briede, Jacco J.; van Breda, Simone G.; Jennen, Danyel G. J.; Medina-Reyes, Estefany I.; Delgado-Buenrostro, Norma L.; Chirino, Yolanda I.; van Loveren, Henk; de Kok, Theo M.
A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
2023-09-114
OA
Gall, Louis; Jardi, Ferran; Lammens, Lieve; Pinero, Janet; Souza, Terezinha M.; Rodrigues, Daniela; Jennen, Danyel G. J.; de Kok, Theo M.; Coyle, Luke; Chung, Seung-Wook; Ferreira, Sofia; Jo, Heeseung; Beattie, Kylie A.; Kelly, Colette; Duckworth, Carrie A.; Pritchard, D. Mark; Pin, Carmen
Reply to Kaminski, NE; Cohen, SM Comment on Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256

回复Kaminski，NE; Cohen，SM对Bischoff等人的评论。食品添加剂二氧化钛 (E171) 对结肠直肠癌转基因小鼠模型结肠中肿瘤形成和基因表达的影响。纳米材料2022，12，1256

NANOMATERIALS
IF4.3
2023-05-050
OAAI
Bischoff, Nicolaj S.; Proquin, Heloise; Jetten, Marlon J.; Schrooders, Yannick; Jonkhout, Marloes C. M.; Briede, Jacco J.; van Breda, Simone G.; Jennen, Danyel G. J.; Medina-Reyes, Estefany I.; Delgado-Buenrostro, Norma L.; Chirino, Yolanda I.; van Loveren, Henk; de Kok, Theo M.
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids
ARCHIVES OF TOXICOLOGY
IF6.9
2021-06-2027
OAAI
Rodrigues, Daniela; de Souza, Terezinha; Coyle, Luke; Di Piazza, Matteo; Herpers, Bram; Ferreira, Sofia; Zhang, Mian; Vappiani, Johanna; Sevin, Daniel C.; Gabor, Attila; Lynch, Anthony; Chung, Seung-Wook; Saez-Rodriguez, Julio; Jennen, Danyel G. J.; Kleinjans, Jos C. S.; de Kok, Theo M.
Safer chemicals using less animals: kick-off of the European ONTOX project
TOXICOLOGY
IF4.6
2021-06-0154
OAAI
Vinken, Mathieu; Benfenati, Emilio; Busquet, Francois; Castell, Jose; Clevert, Djork-Arne; de Kok, Theo M.; Dirven, Hubert; Fritsche, Ellen; Geris, Liesbet; Gozalbes, Rafael; Hartung, Thomas; Jennen, Danyel; Jover, Ramiro; Kandarova, Helena; Kramer, Nynke; Krul, Cyrille; Luechtefeld, Thomas; Masereeuw, Rosalinde; Roggen, Erwin; Schaller, Stephan; Vanhaecke, Tamara; Yang, Chihae; Piersma, Aldert H.

研究方向

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J
Jos Kleinjans
H 指数:60论文数:536被引数:1.4万
T
Theo M. de Kok
H 指数:48论文数:234被引数:9,323
S
Simone G. van Breda
H 指数:26论文数:71被引数:3,488
J
Jacob J. Briedé
H 指数:36论文数:118被引数:5,395
T
Terezinha Souza
H 指数:17论文数:77被引数:911
S
Sandra M.H. Claessen
H 指数:29论文数:98被引数:2,057
M
Marlon J. Jetten
H 指数:15论文数:36被引数:589
J
Joost H.M. van Delft
H 指数:38论文数:167被引数:3,675
M
Marcel van Herwijnen
H 指数:16论文数:70被引数:920
M
Maria Tsamou
H 指数:13论文数:32被引数:673