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S

Simon Lovestone

department of psychiatry, university of oxford , oxford ox1 2jd ,
H指数:117
被引数:6.4万

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Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

APOE基因型与脑脊液蛋白质组的关联揭示了阿尔茨海默病中不同的保护机制和风险机制

Alzheimer's & Dementia
IF11.1
2025-10-140
OAAI
Eleonora M. Vromen; Senne B. Lageman; Johan Gobom; Rik van der Kant; Valerija Dobricic; Lars Bertram; Johannes Streffer; Simon Lovestone; Stephanie J. B. Vos; Mikel Tainta; Yvonne Freund-Levi; Lutz Frölich; Julius Popp; Gwendoline Peyratout; Magda Tsolaki; Frans Verhey; Rik Vandenberghe; Jolien Schaeverbeke; Kaj Blennow; Sven J. van der Lee; Philip Scheltens; Yolande A. L. Pijnenburg; Wiesje M. van der Flier; Charlotte E. Teunissen; Henrik Zetterberg; Pieter Jelle Visser; Betty Tijms
Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology

认知功能正常个体中疑似非阿尔茨海默病病理生理机制的脑脊液蛋白质组学分析

Brain Communications
IF4.5
2025-06-200
OAAI
Aurore Delvenne; Johan Gobom; Lianne M Reus; Valerija Dobricic; Mara ten Kate; Suzanne E Schindler; Inez Ramakers; Betty M Tijms; Rik Vandenberghe; Jolien Schaeverbeke; Pablo Martinez-Lage; Mikel Tainta; Charlotte E Teunissen; Julius Popp; Gwendoline Peyratout; Magda Tsolaki; Yvonne Freund-Levi; Simon Lovestone; Johannes Streffer; Frederik Barkhof; Lars Bertram; Kaj Blennow; Henrik Zetterberg; Pieter Jelle Visser; Stephanie J B Vos
Synaptic protein CSF levels relate to memory scores in individuals without dementia

突触蛋白CSF水平与无痴呆个体的记忆评分相关

ALZHEIMERS RESEARCH & THERAPY
IF7.6
2025-03-030
OA
Wesenhagen, KEJ; de Leeuw, DM; Tomassen, J; Gobom, J; Bos, I; Vos, SJB; Martinez-Lage, P; Tainta, M; Popp, J; Peyratout, G; Tsolaki, M; Vandenberghe, R; Freund-Levi, Y; Verhey, F; Lovestone, S; Streffer, J; Dobricic, V; Blennow, K; Scheltens, P; Smit, AB; Bertram, L; Teunissen, CE; Zetterberg, H; Tijms, BM; Visser, PJ
Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers
Stem Cells
IF3.6
2024-12-200
PRE
Rowland, Helen A.; Miller, Georgina; Liu, Qiang; Li, Shuhan; Sharp, Nicola R.; Ng, Bryan; Wei, Tina; Arunasalam, Kanisa; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Zetterberg, Henrik; Cader, M. Zameel; Wade-Martins, Richard; Lovestone, Simon; Nevado-Holgado, Alejo; Kormilitzin, Andrey; Buckley, Noel J.
Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies
FLUIDS AND BARRIERS OF THE CNS
IF6.2
2024-07-183
OAAI
Delvenne, Aurore; Vandendriessche, Charysse; Gobom, Johan; Burgelman, Marlies; Dujardin, Pieter; De Nolf, Clint; Tijms, Betty M.; Teunissen, Charlotte E.; Schindler, Suzanne E.; Verhey, Frans; Ramakers, Inez; Martinez-Lage, Pablo; Tainta, Mikel; Vandenberghe, Rik; Schaeverbeke, Jolien; Engelborghs, Sebastiaan; De Roeck, Ellen; Popp, Julius; Peyratout, Gwendoline; Tsolaki, Magda; Freund-Levi, Yvonne; Lovestone, Simon; Streffer, Johannes; Bertram, Lars; Blennow, Kaj; Zetterberg, Henrik; Visser, Pieter Jelle; Vandenbroucke, Roosmarijn E.; Vos, Stephanie J. B.
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
ALZHEIMERS & DEMENTIA
IF11.1
2024-07-061
OA
Delvenne, Aurore; Gobom, Johan; Schindler, Suzanne E.; ten Kate, Mara; Reus, Lianne M.; Dobricic, Valerija; Tijms, Betty M.; Benzinger, Tammie L. S.; Cruchaga, Carlos; Teunissen, Charlotte E.; Ramakers, Inez; Martinez-Lage, Pablo; Tainta, Mikel; Vandenberghe, Rik; Schaeverbeke, Jolien; Engelborghs, Sebastiaan; De Roeck, Ellen; Popp, Julius; Peyratout, Gwendoline; Tsolaki, Magda; Freund-Levi, Yvonne; Lovestone, Simon; Streffer, Johannes; Barkhof, Frederik; Bertram, Lars; Blennow, Kaj; Zetterberg, Henrik; Visser, Pieter Jelle; Vos, Stephanie J. B.
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease
ALZHEIMERS & DEMENTIA
IF11.1
2023-02-154
OA
Shi, Liu; Xu, Jin; Green, Rebecca; Wretlind, Asger; Homann, Jan; Buckley, Noel J.; Tijms, Betty M.; Vos, Stephanie J. B.; Lill, Christina M.; ten Kate, Mara; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Streffer, Johannes; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Lovestone, Simon; Bertram, Lars; Nevado-Holgado, Alejo J.; Proitsi, Petroula; Legido-Quigley, Cristina
Identification of a possible proteomic biomarker in Parkinson's disease: discovery and replication in blood, brain and cerebrospinal fluid
BRAIN COMMUNICATIONS
IF4.5
2022-12-2815
OAAI
Winchester, Laura; Barber, Imelda; Lawton, Michael; Ash, Jessica; Liu, Benjamine; Evetts, Samuel; Hopkins-Jones, Lucinda; Lewis, Suppalak; Bresner, Catherine; Malpartida, Ana Belen; Williams, Nigel; Gentlemen, Steve; Wade-Martins, Richard; Ryan, Brent; Holgado-Nevado, Alejo; Hu, Michele; Ben-Shlomo, Yoav; Grosset, Donald; Lovestone, Simon
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks
FRONTIERS IN AGING NEUROSCIENCE
IF4.5
2022-11-2911
OAAI
Zhang, Yuting; Ghose, Upamanyu; Buckley, Noel J.; Engelborghs, Sebastiaan; Sleegers, Kristel; Frisoni, Giovanni B.; Wallin, Anders; Lleo, Alberto; Popp, Julius; Martinez-Lage, Pablo; Legido-Quigley, Cristina; Barkhof, Frederik; Zetterberg, Henrik; Visser, Pieter Jelle; Bertram, Lars; Lovestone, Simon; Nevado-Holgado, Alejo J.; Shi, Liu
Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability
BRAIN COMMUNICATIONS
IF4.5
2022-10-218
OAAI
Ng, Bryan; Rowland, Helen A.; Wei, Tina; Arunasalam, Kanisa; Hayes, Emma Mee; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Ffytche, Dominic; Gunn, Roger N.; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh A.; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Buckley, Noel J.; Cader, Zameel M.; Lovestone, Simon; Wade-Martins, Richard
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology
ALZHEIMERS & DEMENTIA
IF11.1
2022-06-147
OA
Delvenne, Aurore; Gobom, Johan; Tijms, Betty; Bos, Isabelle; Reus, Lianne M.; Dobricic, Valerija; Ten Kate, Mara; Verhey, Frans; Ramakers, Inez; Scheltens, Philip; Teunissen, Charlotte E.; Vandenberghe, Rik; Schaeverbeke, Jolien; Gabel, Silvy; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Tsolaki, Magda; Freund-Levi, Yvonne; Lovestone, Simon; Streffer, Johannes; Barkhof, Frederik; Bertram, Lars; Blennow, Kaj; Zetterberg, Henrik; Visser, Pieter Jelle; Vos, Stephanie J. B.
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease (vol 17, pg 1, 2022)

脑脊液tau水平与阿尔茨海默氏病的异常神经元可塑性标志物有关 (第17卷，第1页，2022页)

MOLECULAR NEURODEGENERATION
IF17.5
2022-05-132
OAAI
Visser, Pieter Jelle; Reus, Lianne M.; Gobom, Johan; Jansen, Iris; Dicks, Ellen; van der Lee, Sven J.; Tsolaki, Magda; Verhey, Frans R. J.; Popp, Julius; Martinez-Lage, Pablo; Vandenberghe, Rik; Lleo, Alberto; Molinuevo, Jose Luis; Engelborghs, Sebastiaan; Freund-Levi, Yvonne; Froelich, Lutz; Sleegers, Kristel; Dobricic, Valerija; Lovestone, Simon; Streffer, Johannes; Vos, Stephanie J. B.; Bos, Isabelle; Smit, August B.; Smit, August B.; Blennow, Kaj; Scheltens, Philip; Teunissen, Charlotte E.; Bertram, Lars; Zetterberg, Henrik; Tijms, Betty M.; Smit, August B.; Blennow, Kaj; Scheltens, Philip; Teunissen, Charlotte E.; Bertram, Lars; Zetterberg, Henrik; Tijms, Betty M.
Effects of age, amyloid, sex, and APOE e4 on the CSF proteome in normal cognition
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING
IF4.4
2022-05-066
OA
Wesenhagen, Kirsten E. J.; Gobom, Johan; Bos, Isabelle; Vos, Stephanie J. B.; Martinez-Lage, Pablo; Popp, Julius; Tsolaki, Magda; Vandenberghe, Rik; Freund-Levi, Yvonne; Verhey, Frans; Lovestone, Simon; Streffer, Johannes; Dobricic, Valerija; Bertram, Lars; Blennow, Kaj; Pikkarainen, Maria; Hallikainen, Merja; Kuusisto, Johanna; Laakso, Markku; Soininen, Hilkka; Scheltens, Philip; Zetterberg, Henrik; Teunissen, Charlotte E.; Visser, Pieter Jelle; Tijms, Betty M.
Genome- and epigenome-wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING
IF4.4
2022-04-203
OAAI
Hillary, Robert F.; Gadd, Danni A. A.; McCartney, Daniel L. L.; Shi, Liu; Campbell, Archie; Walker, Rosie M. M.; Ritchie, Craig W. W.; Deary, Ian J. J.; Evans, Kathryn L. L.; Nevado-Holgado, Alejo J. J.; Hayward, Caroline; Porteous, David J. J.; McIntosh, Andrew M. M.; Lovestone, Simon; Robinson, Matthew R. R.; Marioni, Riccardo E. E.
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease

脑脊液tau水平与阿尔茨海默氏病的异常神经元可塑性标志物相关

MOLECULAR NEURODEGENERATION
IF17.5
2022-03-2843
OAAI
Visser, Pieter Jelle; Reus, Lianne M.; Gobom, Johan; Jansen, Iris; Dicks, Ellen; van der Lee, Sven J.; Tsolaki, Magda; Verhey, Frans R. J.; Popp, Julius; Martinez-Lage, Pablo; Vandenberghe, Rik; Lleo, Alberto; Molinuevo, Jose Luis; Engelborghs, Sebastiaan; Freund-Levi, Yvonne; Froelich, Lutz; Sleegers, Kristel; Dobricic, Valerija; Lovestone, Simon; Streffer, Johannes; Vos, Stephanie J. B.; Bos, Isabelle; Smit, August B.; Blennow, Kaj; Scheltens, Philip; Teunissen, Charlotte E.; Bertram, Lars; Zetterberg, Henrik; Tijms, Betty M.
Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset

欧洲阿尔茨海默病多模态生物标志物发现数据集医学信息框架中阿尔茨海默病脑成像生物标志物和神经心理学表型的全基因组关联研究

FRONTIERS IN AGING NEUROSCIENCE
IF4.5
2022-03-2124
OA
Homann, Jan; Osburg, Tim; Ohlei, Olena; Dobricic, Valerija; Deecke, Laura; Bos, Isabelle; Vandenberghe, Rik; Gabel, Silvy; Scheltens, Philip; Teunissen, Charlotte E.; Engelborghs, Sebastiaan; Frisoni, Giovanni; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Lleo, Alberto; Alcolea, Daniel; Popp, Julius; Clark, Christopher; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Dobson, Richard J. B.; Legido-Quigley, Cristina; Sleegers, Kristel; Van Broeckhoven, Christine; Wittig, Michael; Franke, Andre; Lill, Christina M.; Blennow, Kaj; Zetterberg, Henrik; Lovestone, Simon; Streffer, Johannes; ten Kate, Mara; Vos, Stephanie J. B.; Barkhof, Frederik; Visser, Pieter Jelle; Bertram, Lars

研究方向

暂未获取到该数据
M
Magda Tsolaki
H 指数:102论文数:1,007被引数:5.6万
P
Patrizia Mecocci
H 指数:105论文数:634被引数:4.6万
H
Hilkka Soininen
H 指数:144论文数:1,229被引数:10.9万
P
Powell, John
H 指数:0论文数:3被引数:202
I
Iwona Kłoszewska
H 指数:63论文数:347被引数:1.7万
J
Julie Williams
H 指数:83论文数:602被引数:4.4万
A
Andrew Simmons
H 指数:102论文数:431被引数:3.6万
P
Petroula Proitsi
H 指数:55论文数:202被引数:3.1万
B
Bruno Vellas
H 指数:0论文数:7被引数:679
H
Henrik Zetterberg
H 指数:190论文数:3,761被引数:18.1万