Peter Lobel - Publications, H-index & Citations

Peter Lobel

Rutgers University

54H指数

122论文数

9.5K被引数

收录论文 63

发表时间

Elevated tripeptidyl-peptidase 1 corrects multiple phenotypes of disease in a mouse model of juvenile neuronal ceroid lipofuscinosis 升高的三肽基肽酶1纠正幼年神经元蜡样脂褐质沉积症小鼠模型中的多种疾病表型

Molecular Therapy Methods & Clinical Development

IF4.7

2025-09-03

OAAI

Whitney Banach-Petrosky; Katherine E. Larrimore; Elizabeth H. Sleat; Allyson Bazer; Benjamin Samuels; Yalun Tan; Andrew C. Melton; Justin K. Ichida; Todd P. Logan; Peter Lobel; David E. Sleat

Thermal Stability of Animal Orthologs of the Lysosomal Protease Tripeptidyl-peptidase 1 Does Not Correlate with Cellular Half-life: Implications for Evolutionary Redesign of the Human Enzyme

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-01

OAAI

Modak, Anurag; Banach-Petrosky, Whitney; Sleat, David; Lobel, Peter

Elevated levels of tripeptidyl peptidase 1 do not ameliorate pathogenesis in a mouse model of Alzheimer disease 三肽基肽酶1水平升高不能改善阿尔茨海默病小鼠模型的发病机制

NEUROBIOLOGY OF AGING

IF3.5

2022-10-01

OAAI

Sleat, David E.; Maita, Isabella; Banach-Petrosky, Whitney; Larrimore, Katherine E.; Liu, Tonia; Cruz, Dana; Baker, Lukas; Maxfield, Frederick R.; Samuels, Benjamin; Lobel, Peter

Novel Polyanionic Tracts Improve Expression of a TPP1:K16ApoE Chimera

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Modak, Anurag; Banach-Petrosky, Whitney; Sleat, David E.; Lobel, Peter

A Method to Estimate the Distribution of Proteins across Multiple Compartments Using Data from Quantitative Proteomics Subcellular Fractionation Experiments

JOURNAL OF PROTEOME RESEARCH

IF3.6

2022-05-06

PREAI

Moore, Dirk F.; Sleat, David E.; Lobel, Peter

Comparative Analysis of Quantitative Mass Spectrometric Methods for Subcellular Proteomics

JOURNAL OF PROTEOME RESEARCH

IF3.6

2020-03-05

OAAI

Tannous, Abla; Boonen, Marielle; Zheng, Haiyan; Zhao, Caifeng; Germain, Colin J.; Moore, Dirk F.; Sleat, David E.; Jadot, Michel; Lobel, Peter

Lysosomal protein thermal stability does not correlate with cellular half-life: global observations and a case study of tripeptidyl-peptidase 1

BIOCHEMICAL JOURNAL

IF4.3

2020-02-14

OAAI

Collier, Aaron M.; Nemtsova, Yuliya; Kuber, Narendra; Banach-Petrosky, Whitney; Modak, Anurag; Sleat, David E.; Nanda, Vikas; Lobel, Peter

Analysis of Brain and Cerebrospinal Fluid from Mouse Models of the Three Major Forms of Neuronal Ceroid Lipofuscinosis Reveals Changes in the Lysosomal Proteome

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2019-11-01

OAAI

Sleat, David E.; Wiseman, Jennifer A.; El-Banna, Mukarram; Zheng, Haiyan; Zhao, Caifeng; Soherwardy, Amenah; Moore, Dirk F.; Lobel, Peter

Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain 溶酶体酶三肽基肽酶1通过 β-折叠结构域内的多个内切蛋白水解切割使原纤维a β 不稳定

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-01-29

OAAI

Sole-Domenech, Santiago; Rojas, Ana V.; Maisuradze, Gia G.; Scheraga, Harold A.; Lobel, Peter; Maxfield, Frederick R.

Proteomic Analysis of Brain and Cerebrospinal Fluid from the Three Major Forms of Neuronal Ceroid Lipofuscinosis Reveals Potential Biomarkers 来自三种主要形式的神经元类固醇脂褐质病的脑和脑脊液的蛋白质组学分析揭示了潜在的生物标志物

JOURNAL OF PROTEOME RESEARCH

IF3.6

2017-08-28

OAAI

Sleat, David E.; Tannous, Abla; Sohar, Istvan; Wiseman, Jennifer A.; Zheng, Haiyan; Qian, Meqian; Zhao, Caifeng; Xin, Winnie; Barone, Rosemary; Sims, Katherine B.; Moore, Dirk F.; Lobel, Peter

Using whole-exome sequencing to investigate the genetic bases of lysosomal storage diseases of unknown etiology 使用全外显子组测序研究病因不明的溶酶体贮积病的遗传基础

HUMAN MUTATION

IF3.7

2017-07-25

OAAI

Wang, Nan; Zhang, Yeting; Gedvilaite, Erika; Loh, Jui Wan; Lin, Timothy; Liu, Xiuping; Liu, Chang-Gong; Kumar, Dibyendu; Donnelly, Robert; Raymond, Kimiyo; Schuchman, Edward H.; Sleat, David E.; Lobel, Peter; Xing, Jinchuan

A Basic ApoE-Based Peptide Mediator to Deliver Proteins across the Blood-Brain Barrier: Long-Term Efficacy, Toxicity, and Mechanism

MOLECULAR THERAPY

IF12

2017-07-01

OAAI

Meng, Yu; Wiseman, Jennifer A.; Nemtsova, Yuliya; Moore, Dirk F.; Guevarra, Jenieve; Reuhl, Kenneth; Banks, William A.; Daneman, Richard; Sleat, David E.; Lobel, Peter

Accounting for Protein Subcellular Localization: A Compartmental Map of the Rat Liver Proteome

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2017-02-01

OAAI

Jadot, Michel; Boonen, Marielle; Thirion, Jaqueline; Wang, Nan; Xing, Jinchuan; Zhao, Caifeng; Tannous, Abla; Qian, Meiqian; Zheng, Haiyan; Everett, John K.; Moore, Dirk F.; Sleat, David E.; Lobel, Peter

Effective Intravenous Therapy for Neurodegenerative Disease With a Therapeutic Enzyme and a Peptide That Mediates Delivery to the Brain

MOLECULAR THERAPY

IF12

2014-03-01

OAAI

Meng, Yu; Sohar, Istvan; Sleat, David E.; Richardson, Jason R.; Reuhl, Kenneth R.; Jenkins, Robert B.; Sarkar, Gobinda; Lobel, Peter

Extending the Mannose 6-Phosphate Glycoproteome by High Resolution/Accuracy Mass Spectrometry Analysis of Control and Acid Phosphatase 5-Deficient Mice

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2013-07-01

OAAI

Sleat, David E.; Sun, Pengling; Wiseman, Jennifer A.; Huang, Ling; El-Banna, Mukarram; Zheng, Haiyan; Moore, Dirk F.; Lobel, Peter

Proteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain

PROTEOMICS

IF3.9

2012-11-22

OAAI

Sleat, David E.; Wiseman, Jennifer A.; Sohar, Istvan; El-Banna, Mukarram; Zheng, Haiyan; Moore, Dirk F.; Lobel, Peter

Intrathecal tripeptidyl-peptidase 1 reduces lysosomal storage in a canine model of late infantile neuronal ceroid lipofuscinosis 鞘内三肽基肽酶1可减少晚期婴儿神经元蜡样脂褐质病犬模型中的溶酶体储存

MOLECULAR GENETICS AND METABOLISM

IF3.5

2011-11-01

PREAI

Vuillemenot, Brian R.; Katz, Martin L.; Coates, Joan R.; Kennedy, Derek; Tiger, Pascale; Kanazono, Shinichi; Lobel, Peter; Sohar, Istvan; Xu, Su; Cahayag, Rhea; Keve, Steve; Koren, Eugen; Bunting, Stuart; Tsuruda, Laurie S.; O'Neill, Charles A.

Large-volume Intrathecal Enzyme Delivery Increases Survival of a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

MOLECULAR THERAPY

IF12

2011-10-01

OAAI

Xu, Su; Wang, Lingling; El-Banna, Mukarram; Sohar, Istvan; Sleat, David E.; Lobel, Peter

Classification of Subcellular Location by Comparative Proteomic Analysis of Native and Density-shifted Lysosomes

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2011-04-01

OAAI

Della Valle, Maria Cecilia; Sleat, David E.; Zheng, Haiyan; Moore, Dirk F.; Jadot, Michel; Lobel, Peter