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Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles 连接体修饰能够控制大环化合物中关键官能团的取向 Brudy, Christian; Ruijsenaars, Enrico; Meyners, Christian; Sugiarto, Wisely O.; Achaq, Hanaa; Spiske, Moritz; Buffa, Vanessa; Springer, Margherita; Repity, Maximilian; Weller, Arjen; Haferkamp, Undine; Pless, Ole; Muschong, Patricia; Miltner, Dominik; Mezler, Mario; Schmidt, Mathias V.; Riniker, Sereina; Hausch, Felix 分享 收藏
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FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice FKBP51在谷氨酸能前脑神经元中促进雌性小鼠早期生活应激接种。 van Doeselaar, Lotte; Abromeit, Alexandra; Stark, Tibor; Menegaz, Danusa; Ballmann, Markus; Mitra, Shiladitya; Yang, Huanqing; Rehawi, Ghalia; Huettl, Rosa-Eva; Bordes, Joeri; Narayan, Sowmya; Harbich, Daniela; Deussing, Jan M.; Rammes, Gerhard; Czisch, Michael; Knauer-Arloth, Janine; Eder, Matthias; Lopez, Juan Pablo; Schmidt, Mathias V. 分享 收藏
Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism Bordes, Joeri; Bajaj, Thomas; Miranda, Lucas; van Doeselaar, Lotte; Brix, Lea Maria; Narayan, Sowmya; Yang, Huanqing; Mitra, Shiladitya; Kovarova, Veronika; Springer, Margherita; Kleigrewe, Karin; Mueller-Myhsok, Bertram; Gassen, Nils C.; Schmidt, Mathias V. 分享 收藏
HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice Contreras, Raian E.; Gruber, Tim; Gonzalez-Garcia, Ismael; Schriever, Sonja C.; De Angelis, Meri; Mallet, Noemi; Bernecker, Miriam; Legutko, Beata; Kabra, Dhiraj; Schmidt, Mathias; Tschoep, Matthias H.; Gutierrez-Aguilar, Ruth; Mellor, Jane; Garcia-Caceres, Cristina; Pfluger, Paul T. 分享 收藏
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Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice 抑制Hippo通路激酶释放WWC1促进小鼠AMPAR依赖性突触可塑性和长时记忆 Stepan, Jens; Heinz, Daniel E.; Dethloff, Frederik; Wiechmann, Svenja; Martinelli, Silvia; Hafner, Kathrin; Ebert, Tim; Junglas, Ellen; Haeusl, Alexander S.; Poehlmann, Max L.; Jakovcevski, Mira; Pape, Julius C.; Zannas, Anthony S.; Bajaj, Thomas; Hermann, Anke; Ma, Xiao; Pavenstaedt, Hermann; Schmidt, Mathias V.; Philipsen, Alexandra; Turck, Christoph W.; Deussing, Jan M.; Rammes, Gerhard; Robinson, Andrew C.; Payton, Antony; Wehr, Michael C.; Stein, Valentin; Murgatroyd, Christopher; Kremerskothen, Joachim; Kuster, Bernhard; Wotjak, Carsten T.; Gassen, Nils C. 分享 收藏
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration Hartmann, Jakob; Bajaj, Thomas; Otten, Joy; Klengel, Claudia; Ebert, Tim; Gellner, Anne-Kathrin; Junglas, Ellen; Hafner, Kathrin; Anderzhanova, Elmira A.; Tang, Fiona; Missig, Galen; Rexrode, Lindsay; Trussell, Daniel T.; Li, Katelyn X.; Pohlmann, Max L.; Mackert, Sarah; Geiger, Thomas M.; Heinz, Daniel E.; Lardenoije, Roy; Dedic, Nina; McCullough, Kenneth M.; Prochnicki, Tomasz; Rhomberg, Thomas; Martinelli, Silvia; Payton, Antony; Robinson, Andrew C.; Stein, Valentin; Latz, Eicke; Carlezon, William A., Jr.; Hausch, Felix; Schmidt, Mathias V.; Murgatroyd, Chris; Berretta, Sabina; Klengel, Torsten; Pantazopoulos, Harry; Ressler, Kerry J.; Gassen, Nils C. 分享 收藏
Efficacy and safety data (52-week) from a phase 1/2 trial and extension study of JR-171 (lepunafusp alfa) used in enzyme replacement therapy for patients with MPS I Giugliani, Roberto; Harmatz, Paul; Martins, Ana Maria; Hamazaki, Takashi; Kira, Ryutaro; Kubo, Toru; Sato, Yuji; Moriuchi, Hiroaki; Kawashima, Satoshi; Ikeda, Toshiaki; So, Sairei; Tanizawa, Kazunori; Schmidt, Mathias 分享 收藏
Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus Kos, Aron; Lopez, Juan Pablo; Bordes, Joeri; de Donno, Carlo; Dine, Julien; Brivio, Elena; Karamihalev, Stoyo; Luecken, Malte D.; Almeida-Correa, Suellen; Gasperoni, Serena; Dick, Alec; Miranda, Lucas; Buettner, Maren; Stoffel, Rainer; Flachskamm, Cornelia; Theis, Fabian J.; Schmidt, Mathias V.; Chen, Alon 分享 收藏
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Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus Brivio, Elena; Kos, Aron; Ulivi, Alessandro Francesco; Karamihalev, Stoyo; Ressle, Andrea; Stoffel, Rainer; Hirsch, Dana; Stelzer, Gil; Schmidt, Mathias V.; Lopez, Juan Pablo; Chen, Alon 分享 收藏