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T

Thomas Thum

Hannover Medical School
H指数:109
被引数:4.3万

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荣誉奖项

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Nucleoside-Modified mRNA Encoding Alpha-Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC-Derived Cardiomyocytes

核苷修饰的mRNA编码α-半乳糖苷酶A改善人类iPSC来源的心肌细胞中的法布里病表型

Advanced Science
IF14.1
2026-08-280
OAAI
Malte Juchem; Lea Oehlsen; Sedef Ersoy; Jia Li Ye; Natalie Weber; Elisa Mohr; Wilson Agyapong; Junqing Liu; Maximilian Fuchs; Ke Xiao; Christopher Jahn; Reto Eggenschwiler; Tobias Cantz; Julia Beimdiek; Falk F. R. Buettner; Theresia Kraft; Jan Hegermann; Ivonne J. Knorr; Lisa Ernst; Linda Feldbrügge; Resa Puffert; Kevin Schmidt; Christian Bär; Jeannine Hoepfner; Thomas Thum
Integrated Multi-Omics Analysis Uncovers Molecular Dysregulation in Glucosylceramide Synthase-Deficient Human Induced Pluripotent Stem Cells

整合多组学分析揭示葡糖基神经酰胺合成酶缺陷型人诱导多能干细胞中的分子失调

MOLECULAR & CELLULAR PROTEOMICS
IF5.5
2026-08-010
PRE
Beimdiek, Julia; Cirksena, Karsten; Rossdam, Charlotte; Brand-Merseburger, Smilla; Oberbeck, Astrid; Barbosa, Philippe V.; Tzvetkova, Ana; Juchem, Malte; Baer, Christian; Thum, Thomas; Schambach, Axel; Pich, Andreas; Bruegger, Britta; Kuss, Andreas W.; Buettner, Falk F. R.
Preclinical evaluation of cysteine protease-inhibitor aloxistatin (E64d) for heart failure therapy

半胱氨酸蛋白酶抑制剂aloxistatin (E64d)在心力衰竭治疗中的临床前评估

JOURNAL OF MOLECULAR MEDICINE-JMM
IF4.2
2026-06-250
OAAI
Maria Jordan; Angelika Stucki-Koch; Maximilian Schinke; Lena Willmer; Ingrid Senne; Naisam Abbas; Marco Bentele; Dana Oldenkott; Nico Lachmann; Linda Feldbrügge; Resa Puffert; Josef Fangmann; Robert Ramm; Thomas Thum; Katherina Sewald; Kevin Schmidt; Jan Fiedler
Serotonin 5-HT7 receptor signaling modulates inflammatory responses and survival after myocardial infarction

5-HT7受体信号调节心肌梗死后炎症反应和存活

Journal of Translational Medicine
IF7.5
2026-06-170
OA
Franziska E. Müller; Frauke S. Bahr; Sergej Erschow; Martina Kasten; Maren Heimerl; Nils Benen; Mira Jung; Arne Schmidt; Michaela Scherr; Christine S. Falk; Christian Bustamante; Igor Ponomarev; Johann Bauersachs; Denise Hilfiker-Kleiner; Thomas Thum; Evgeni G. Ponimaskin; Melanie Ricke-Hoch
Increase in mechanical load and pro-fibrotic stimulation leads to fibrotic and hypertrophic remodeling in porcine living myocardial slices

机械负荷增加和促纤维化刺激会导致猪活体心肌切片发生纤维化和肥大性重塑。

Scientific Reports
IF3.9
2025-11-210
OAAI
Marco Bentele; Sophie Linke; Susanne Neumüller; Andrea Korte; Anika Gietz; Annette Just; Angelika Stucki-Koch; Angelika Pfanne; Junqing Liu; Jiahao Zhao; Cornelia Schwennen; Christian Homann; Christian Visscher; Michael Pflaum; Bettina Wiegmann; Christian Bär; Natalie Weber; Jan Fiedler; Thomas Thum
The RNA-binding protein Quaking is essential for cardiac homeostasis and function by regulating Morf4l2 splicing

RNA结合蛋白Quaking通过调控Morf4l2的剪接对心脏稳态和功能至关重要。

Journal of Molecular and Cellular Cardiology
IF4.7
2025-11-080
PRE
Sunaina Kumari; null Shashi; Sandhya Singh; Abinash Swain; Shakti Prakash; Pragya Chitkara; Rakesh Kumar Sharma; Pratyush Agarwal; Samprikta Kundu; Aakash Gaur; Renu Kumari; Abhipsa Sinha; Shambhabi Chatterjee; Pankaj Prasun; Oliver Hummel; Bhaskar Pant; Kinshuk Raj Srivastava; Norbert Hübner; Dipak Datta; Kalyan Mitra; Durga Prasad Mishra; Rajdeep Guha; Thomas Thum; Shailesh Kumar; Shashi Kumar Gupta
Type I IFNs Decrease SARS-CoV-2 Replication in Human Cardiomyocytes and Increase Cytokine Production in Macrophages

I型IFNs在人类心肌细胞中抑制SARS-CoV-2复制，并在巨噬细胞中增加细胞因子产生。

Journal of Clinical Immunology
IF5.7
2025-10-210
OA
Verónica Durán; Eirini Nikolouli; Shambhabi Chatterjee; Bibiana Costa; Andreas Pavlou; Annett Ziegler; Jennifer Becker; Kira Baumann; Matthias Bruhn; Kathrin Haake; Anna Rafiei Hashtchin; Ingrid Gensch; Andrea Korte; Yvonne Lisa Behrens; Shen-Ying Zhang; Jean-Laurent Casanova; Christian Bär; Nico Lachmann; Thomas Thum; Ulrich Kalinke
A circular RNA derived from the ryanodine receptor 2 locus controls cardiac hypertrophy and calcium handling

一种源自ryanodine receptor 2位点的环状RNA调控心肌肥厚和钙处理

Cellular and Molecular Life Sciences
IF6.2
2025-10-210
OA
Wen Pan; Hannah J. Hunkler; Shambhabi Chatterjee; Dongchao Lu; Isabelle Riedel; Anika Gietz; Ke Xiao; Maximilian Fuchs; Dimyana Neufeldt; Theresia Kraft; Cheng-Kai Huang; Sarah Cushman; Anne Bührke; Arne Schmidt; Elisa Mohr; Natalie Weber; Christian Bär; Thomas Thum
Pathophysiology and clinical use of agents with vasodilator properties in acute heart failure. A scientific statement of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

急性心力衰竭中血管扩张剂的作用机制与临床应用。欧洲心脏病学会（ESC）心力衰竭协会（HFA）的科学声明。

EUROPEAN JOURNAL OF HEART FAILURE
IF10.8
2025-05-040
PRE
Chioncel, Ovidiu; Mebazaa, Alexandre; Farmakis, Dimitrios; Abdelhamid, Magdy; Lund, Lars H.; Harjola, Veli-Pekka; Anker, Stefan; Filippatos, Gerasimos; Ben-Gal, Tuvia; Damman, Kevin; Skouri, Hadi; Antohi, Laura; Collins, Sean P.; Adamo, Marianna; Miro, Oscar; Hill, Loreena; Parissis, John; Moura, Brenda; Mueller, Christian; Jankowska, Ewa; Lopatin, Yury; Dunlap, Mark; Volterrani, Maurizio; Fudim, Marat; Flammer, Andreas J.; Mullens, Wilfried; Pang, Peter S.; Tica, Otilia; Ponikowski, Piotr; Ristic, Arsen; Butler, Javed; Savarese, Gianluigi; Cicoira, Mariantonietta; Thum, Thomas; Bayes Genis, Antoni; Polyzogopoulou, Effie; Seferovic, Petar; Yilmaz, Mehmet Birhan; Rosano, Giuseppe; Coats, Andrew J. S.; Metra, Marco

研究方向

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B
Bauersachs, Johann
H 指数:0论文数:5被引数:0
C
Christian Bär
H 指数:37论文数:146被引数:5,254
J
Jan Fiedler
H 指数:39论文数:113被引数:9,471
S
Sándor Bátkai
H 指数:71论文数:184被引数:2.2万
S
Shashi Kumar Gupta
H 指数:45论文数:118被引数:1.6万
K
Ke Xiao
H 指数:31论文数:192被引数:4,351
A
Andrew J.S. Coats
H 指数:152论文数:1,155被引数:16.6万
P
Petar Seferović
H 指数:96论文数:427被引数:6.5万
O
Ovidiu Chioncel
H 指数:69论文数:549被引数:4.8万
C
Carlo G. Tocchetti
H 指数:69论文数:318被引数:3.1万