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W

William Bourguet

CNRS
H指数:47
被引数:1.0万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse

使用基于强效激动剂的PROTAC靶向孕烷X受体以延缓结肠癌复发

Oncogenesis
IF6.4
2025-08-300
OAAI
Lucile Bansard; Guillaume Laconde; Vanessa Delfosse; Tiphaine Huet; Margaux Ayeul; Emilie Rigal; Quentin Donati; Sabine Gerbal-Chaloin; Martine Daujat-Chavanieu; Luc Brunel; Baptiste Legrand; Alain Chavanieu; Anthony R. Martin; Julie Pannequin; William Bourguet; Muriel Amblard; Jean Marc Pascussi
An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice (vol 16, 1280, 2025)

一种丰富的姜黄化合物 furanodienone 通过异源核受体 PXR 缓解小鼠肠道炎症（卷 16，1280，2025）

NATURE COMMUNICATIONS
IF15.7
2025-03-030
OA
Wang, Xiaojuan; Zhang, Guohui; Bian, Zhiwei; Chow, Vimanda; Grimaldi, Marina; Carivenc, Coralie; Sirounian, Savannah; Li, Hao; Sladekova, Lucia; Motta, Stefano; Luperi, Yulia; Gong, Yufeng; Costello, Cait; Li, Linhao; Jachimowicz, Matthew; Guo, Miao; Hu, Shian; Wilson, Derek; Balaguer, Patrick; Bourguet, William; Mani, Sridhar; Bonati, Laura; Peng, Hui; March, John; Wang, Hongbing; Wang, Shengpeng; Krause, Henry M.; Liu, Jiabao
Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project (vol 5, 1212509, 2023)

开发用于鉴定和表征内分泌代谢干扰物的新方法方法-PARC项目 (第5卷，1212509，2023)

FRONTIERS IN TOXICOLOGY
IF4.6
2024-03-250
OAAI
Braeuning, Albert; Balaguer, Patrick; Bourguet, William; Carreras-Puigvert, Jordi; Feiertag, Katreece; Kamstra, Jorke H.; Knapen, Dries; Lichtenstein, Dajana; Marx-Stoelting, Philip; Rietdijk, Jonne; Schubert, Kristin; Spjuth, Ola; Stinckens, Evelyn; Thedieck, Kathrin; van den Boom, Rik; Vergauwen, Lucia; von Bergen, Martin; Wewer, Neele; Zalko, Daniel
Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project

开发用于鉴定和表征内分泌代谢干扰物的新方法-PARC项目

FRONTIERS IN TOXICOLOGY
IF4.6
2023-06-2912
OAAI
Braeuning, Albert; Balaguer, Patrick; Bourguet, William; Carreras-Puigvert, Jordi; Feiertag, Katreece; Kamstra, Jorke H.; Knapen, Dries; Lichtenstein, Dajana; Marx-Stoelting, Philip; Rietdijk, Jonne; Schubert, Kristin; Spjuth, Ola; Stinckens, Evelyn; Thedieck, Kathrin; van den Boom, Rik; Vergauwen, Lucia; von Bergen, Martin; Wewer, Neele; Zalko, Daniel
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

激动剂结合的Hsp90-XAP2-AHR胞质复合物的cryo-em结构

NATURE COMMUNICATIONS
IF15.7
2022-11-1664
OAAI
Gruszczyk, Jakub; Grandvuillemin, Loic; Lai-Kee-Him, Josephine; Paloni, Matteo; Savva, Christos G.; Germain, Pierre; Grimaldi, Marina; Boulahtouf, Abdelhay; Kwong, Hok-Sau; Bous, Julien; Ancelin, Aurelie; Bechara, Cherine; Barducci, Alessandro; Balaguer, Patrick; Bourguet, William
Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-12-2844
OAAI
Delfosse, Vanessa; Huet, Tiphaine; Harrus, Deborah; Granell, Meritxell; Bourguet, Maxime; Gardia-Parege, Caroline; Chiavarina, Barbara; Grimaldi, Marina; Le Mevel, Sebastien; Blanc, Pauline; Huang, David; Gruszczyk, Jakub; Demeneix, Barbara; Cianferani, Sarah; Fini, Jean-Baptiste; Balaguer, Patrick; Bourguet, William
Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation
THYROID
IF6.7
2020-08-0121
PREAI
le Maire, Albane; Bouhours-Nouet, Natacha; Soamalala, Jessica; Mirebeau-Prunier, Delphine; Paloni, Matteo; Guee, Laura; Heron, Delphine; Mignot, Cyril; Illouz, Frederic; Joubert, Florence; Briet, Claire; Rodien, Patrice; Bourguet, William; Flamant, Frederic; Guyot, Romain

研究方向

暂未获取到该数据
P
Patrick Balaguer
H 指数:68论文数:303被引数:1.3万
M
Marina Grimaldi
H 指数:28论文数:128被引数:4,135
H
Hinrich Gronemeyer
H 指数:84论文数:437被引数:3.8万
A
Abdelhay Boulahtouf
H 指数:22论文数:45被引数:2,005
V
V. Delfosse
H 指数:22论文数:76被引数:2,647
P
Pierre Germain
H 指数:38论文数:287被引数:6,960
A
Albane le Maire
H 指数:20论文数:64被引数:2,262
Á
Ángel R. de Lera
H 指数:57论文数:464被引数:1.2万
A
Albane le Maire
H 指数:0论文数:0被引数:18
C
Coralie Carivenc
H 指数:6论文数:19被引数:113