John M. Luk - Publications, H-index & Citations

John M. Luk

National University of Singapore

60H指数

368论文数

1.5W被引数

收录论文 111

发表时间

Development of a cadherin-17 (CDH17) immunohistochemistry assay for use as a companion diagnostic for cabotamig in gastrointestinal cancers 开发一种用于cabotamig胃肠道癌伴随诊断的cadherin-17 (CDH17)免疫组织化学检测方法

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Wong, D. A.; Yu, W. S.; Leung, P.; Li, M.; Luk, J. M.

Development of a Trop2/CD3 bispecific antibody with modulated Trop2 binding affinity as a novel immunotherapy for advanced gastrointestinal cancer treatment

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Yee, Chui O.; Wong, Po Yee; Chow, Kronos; Wong, Kwan Wa; Wong, Dennis; Luk, John Moon; Wong, Kwong Fai

Pre-clinical development of ARB011: A CDH17 targeting allogeneic nonviral RNA-based Flash CAR-NK therapy for gastrointestinal cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Roy, Jaydeep; Lin, Nga Tin; Chow, Kronos; Yang, Chih Ya; Lin, James C. L.; Luk, John M.; Wong, Kwong F.

Novel CDH17-targeting antibody-drug conjugate exhibits anti-tumor efficacy in preclinical models of gastrointestinal cancers

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wong, Po Yee; He, Lin; Chow, Kronos; Wong, Kwan Wa; O, Chui Yee; Wong, Dennis; Luk, John Moon; Lo, Pui-Chi; Wong, Kwong Fai

A novel CDH17/PD-1 bispecific antibody for treatment of advanced gastrointestinal cancers

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wong, Kwan Wa; Wong, Po Yee; Chow, Kronos; Yee, Chui O.; Wong, Dennis; Luk, John Moon; Wong, Kwong Fai

Diagnostic application of a novel blood CDH17 immunoassay in the detection of colorectal adenoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lui, Ng; Hon, Felix; Sun, Stella; Leung, Pauline; Ho, David; Luk, John Moon; Foo, Dominic Chi-Chung

The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

IF3.6

2023-02-09

PREAI

Pei, Xiao Meng; Wong, Heong Ting; Ng, Simon Siu Man; Leung, Wing Wa; Wong, Yee Ni; Tsang, Hin Fung; Chan, Amanda Kit Ching; Wong, Yin Kwan Evelyn; Yu, Allen Chi Shing; Yim, Aldrin Kay Yuen; Cho, William Chi Shing; Chan, John Kwok Cheung; Wong, Kwong Fai; Luk, John M.; Tai, William Chi Shing; Wong, Sze Chuen Cesar

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

ELIFE

IF0

2019-09-03

101

OAAI

McMahon, Mary; Contreras, Adrian; Holm, Mikael; Uechi, Tamayo; Forester, Craig M.; Pang, Xiaming; Jackson, Cody; Calvert, Meredith E.; Chen, Bin; Quigley, David A.; Luk, John M.; Kelley, R. Kate; Gordan, John D.; Gill, Ryan M.; Blanchard, Scott C.; Ruggero, Davide

Evaluation of retargeted T cell cytotoxicity of a bispecific antibody targeting CDH17 and CD3 in 2D-and 3D-colon cancer models

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Irigoyen, Macarena; Dai, Eric; Luk, John; Castillo, Gonzalo; Staunton, Don

Serine peptidase inhibitor Kazal type 1 (SPINK1) as novel downstream effector of the cadherin-17/β-catenin axis in hepatocellular carcinoma

CELLULAR ONCOLOGY

IF4.8

2017-06-19

PREAI

Shek, Felix H.; Luo, Ruibang; Lam, Brian Y. H.; Sung, Wing Kin; Lam, Tak-Wah; Luk, John M.; Leung, Ming Sum; Chan, Kin Tak; Wang, Hector K.; Chan, Chung Man; Poon, Ronnie T.; Lee, Nikki P.

LncRNA ANRIL indicates a potential prognostic biomarker in gastric cancer and promotes tumor growth by silencing of miR-99a/miR-449a

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Xu, Zhi; Chen, Jinfei; Luk, John M.; De, Wei

Circulating mortalin autoantibody-a new serological marker of liver cirrhosis

CELL STRESS & CHAPERONES

IF3.2

2015-07-01

OAAI

Lu, Wen-Jing; Saxena, Nishant; Luk, John M.; Kaul, Sunil C.; Wadhwa, Renu

Genomic Predictors for Recurrence Patterns of Hepatocellular Carcinoma: Model Derivation and Validation

PLOS MEDICINE

IF9.9

2014-12-23

OAAI

Kim, Ji Hoon; Sohn, Bo Hwa; Lee, Hyun-Sung; Kim, Sang-Bae; Yoo, Jeong Eun; Park, Yun-Yong; Jeong, Woojin; Lee, Sung Sook; Park, Eun Sung; Kaseb, Ahmed; Kim, Baek Hui; Kim, Wan Bae; Yeon, Jong Eun; Byun, Kwan Soo; Chu, In-Sun; Kim, Sung Soo; Wang, Xin Wei; Thorgeirsson, Snorri S.; Luk, John M.; Kang, Koo Jeong; Heo, Jeonghoon; Park, Young Nyun; Lee, Ju-Seog

Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides 通过使用环状YAP样肽特异性中断yap-tead相互作用来靶向Hippo途径

FASEB JOURNAL

IF4.2

2014-11-10

131

PREAI

Zhou, Zheng; Hu, Taishan; Xu, Zhiheng; Lin, Zhaohu; Zhang, Zhisen; Feng, Teng; Zhu, Liangcheng; Rong, Yiping; Shen, Hong; Luk, John M.; Zhang, Xiongwen; Qin, Ning

miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Xu, Zhi; Liu, Angela; Lee, Nikki; Chen, Jinfei; Luk, John M.

Diverse modes of genomic alteration in hepatocellular carcinoma

GENOME BIOLOGY

IF9.4

2014-08-26

103

OAAI

Jhunjhunwala, Suchit; Jiang, Zhaoshi; Stawiski, Eric W.; Gnad, Florian; Liu, Jinfeng; Mayba, Oleg; Du, Pan; Diao, Jingyu; Johnson, Stephanie; Wong, Kwong-Fai; Gao, Zhibo; Li, Yingrui; Wu, Thomas D.; Kapadia, Sharookh B.; Modrusan, Zora; French, Dorothy M.; Luk, John M.; Seshagiri, Somasekar; Zhang, Zemin

An alternative DNA damage pathway to apoptosis in hematological cancers

NATURE MEDICINE

IF50

2014-06-05

PREAI

Luk, John M.; Guan, Kun-Liang

Dysregulated expression of dickkopfs for potential detection of hepatocellular carcinoma dickkopfs表达异常对肝细胞癌的潜在检测

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

IF3.6

2014-05-09

PREAI

Fatima, Sarwat; Luk, John M.; Poon, Ronnie T. P.; Lee, Nikki P.

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

MOLECULAR CANCER

IF33.9

2014-03-21

160

OAAI

Sethi, Gautam; Chatterjee, Snehajyoti; Rajendran, Peramaiyan; Li, Feng; Shanmugam, Muthu K.; Wong, Kwong Fai; Kumar, Alan Prem; Senapati, Parijat; Behera, Amit K.; Hui, Kam Man; Basha, Jeelan; Natesh, Nagashayana; Luk, John M.; Kundu, Tapas K.

miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma

PLOS ONE

IF2.6

2014-01-23

115

OAAI

Liu, Angela M.; Xu, Zhi; Shek, Felix H.; Wong, Kwong-Fai; Lee, Nikki P.; Poon, Ronnie T.; Chen, Jinfei; Luk, John M.

研究方向