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N

Nicholas J. Lynch

University of Cambridge
H指数:25
被引数:2,816

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Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections

工程化抗体绕过细菌免疫逃逸以驱动补体介导的保护作用抵抗致命感染

Science Translational Medicine
IF14.6
2026-06-170
PRE
Youssif M. Ali; Munehisa Yabuki; Chanuka H. Arachchilage; Priyanka Khatri; Nicholas J. Lynch; Sebastian Bruchmann; Aaron Weimann; Karen Brown; Rodrigo Andres Floto; Julian Parkhill; Vidmantas Petraitis; Ruta Petraitiene; Thomas J. Walsh; David E. Briles; Larry S. MacDaniel; Heidi Utsugi; Galina Gragerova; Ayesha Misquith; Christiana Doulami; Gregory Demopulos; Wilhelm Schwaeble
Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2023-10-255
OAAI
Ali, Youssif M.; Carnell, George W.; Fumagalli, Stefano; Mercurio, Domenico; Seminara, Serena; Lynch, Nicholas J.; Khatri, Priyanka; Arachchilage, Chanuka H.; Mascheroni, Luca; Kaminski, Clemens; George, Charlotte L.; Stewart, Hazel; Yabuki, Munehisa; Demopulos, Gregory; Heeney, Jonathan L.; Schwaeble, Wilhelm
Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

继发性补体缺乏在严重急性新型冠状病毒肺炎期间损害对肺炎克雷伯菌和金黄色葡萄球菌的抗微生物免疫力

FRONTIERS IN IMMUNOLOGY
IF5.9
2022-04-276
OAAI
Ali, Youssif M.; Lynch, Nicholas J.; Khatri, Priyanka; Bamigbola, Ifeoluwa E.; Chan, Andrew C. Y.; Yabuki, Munehisa; Demopulos, Gregory A.; Heeney, Jonathan L.; Pai, Sumita; Baxendale, Helen; Schwaeble, Wilhelm J.
Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2014-03-2446
OAAI
Ali, Youssif Mohammed; Hayat, Azam; Saeed, Bayad Mawlood; Haleem, Kashif S.; Alshamrani, Saleh; Kenawy, Hany I.; Ferreira, Viviana P.; Saggu, Gurpanna; Buchberger, Anna; Lachmann, Peter J.; Sim, Robert B.; Goundis, Dimitrios; Andrew, Peter W.; Lynch, Nicholas J.; Schwaeble, Wilhelm J.
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2011-04-18181
OAAI
Schwaeble, Wilhelm J.; Lynch, Nicholas J.; Clark, James E.; Marber, Michael; Samani, Nilesh J.; Ali, Youssif Mohammed; Dudler, Thomas; Parent, Brian; Lhotta, Karl; Wallis, Russell; Farrar, Conrad A.; Sacks, Steven; Lee, Haekyung; Zhang, Ming; Iwaki, Daisuke; Takahashi, Minoru; Fujita, Teizo; Tedford, Clark E.; Stover, Cordula M.

研究方向

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W
Wilhelm Schwaeble
H 指数:62论文数:243被引数:1.1万
G
Gregory Demopulos
H 指数:14论文数:68被引数:1,099
P
Priyanka Khatri
H 指数:11论文数:61被引数:439
Y
Youssif M. Ali
H 指数:15论文数:45被引数:1,106
S
Silke Roscher
H 指数:8论文数:21被引数:553
C
Cordula Stover
H 指数:28论文数:132被引数:3,807
C
Chanuka H Arachchilage
H 指数:1论文数:15被引数:11
K
Kristin Ladell
H 指数:47论文数:203被引数:8,252
K
Kelly L. Miners
H 指数:24论文数:77被引数:1,635
W
Wioleta M. Zelek
H 指数:21论文数:101被引数:1,452