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D

Darren J. Wight

mrc national institute for medical research
H指数:13
被引数:406
浏览量:0

个人简介

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工作经历

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荣誉奖项

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Excision of Integrated Human Herpesvirus 6A Genomes Using CRISPR/Cas9 Technology
MICROBIOLOGY SPECTRUM
IF3.8
2023-04-130
OAAI
Aimola, Giulia; Wight, Darren J.; Flamand, Louis; Kaufer, Benedikt B.
Chromosome-Specific Human Herpesvirus 6 Integration and Hematologic Malignancies
JOURNAL OF VIROLOGY
IF3.8
2022-09-141
OA
Heldman, Madeleine R.; Wight, Darren J.; Aiewsakun, Pakorn; Aswad, Amr; Fang, Min; Roychoudhury, Pavitra; Stevens-Ayers, Terry; Jerome, Keith R.; Zerr, Danielle M.; Greninger, Alexander L.; Kaufer, Benedikt B.; Boeckh, Michael; Hill, Joshua A.
Impact of Host Telomere Length on HHV-6 Integration
VIRUSES-BASEL
IF3.5
2022-08-240
OAAI
Wight, Darren J.; Aimola, Giulia; Beythien, Georg; Flamand, Louis; Kaufer, Benedikt B.
Visualization of Marek's Disease Virus Genomes in Living Cells during Lytic Replication and Latency
VIRUSES-BASEL
IF3.5
2022-01-291
OAAI
Vychodil, Tereza; Wight, Darren J.; Nascimento, Mariana; Jolmes, Fabian; Korte, Thomas; Herrmann, Andreas; Kaufer, Benedikt B.
Unbiased optical mapping of telomere-integrated endogenous human herpesvirus 6

端粒整合的内源性人类疱疹病毒6的无偏光学作图

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-11-2318
OAAI
Wight, Darren J.; Aimola, Giulia; Aswad, Amr; Lai, Chi-Yu Jill; Bahamon, Christian; Hong, Karl; Hill, Joshua A.; Kaufer, Benedikt B.
Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa
MOLECULAR BIOLOGY AND EVOLUTION
IF5.3
2020-07-2825
OAAI
Aswad, Amr; Aimola, Giulia; Wight, Darren; Roychoudhury, Pavitra; Zimmermann, Cosima; Hill, Joshua; Lassner, Dirk; Xie, Hong; Huang, Meei-Li; Parrish, Nicholas F.; Schultheiss, Heinz-Peter; Venturini, Cristina; Lager, Susanne; Smith, Gordon C. S.; Charnock-Jones, D. Stephen; Breuer, Judith; Greninger, Alexander L.; Kaufer, Benedikt B.
Abrogation of Marek's disease virus replication using CRISPR/Cas9
SCIENTIFIC REPORTS
IF3.9
2020-07-0219
OAAI
Hagag, Ibrahim T.; Wight, Darren J.; Bartsch, Denise; Sid, Hicham; Jordan, Ingo; Bertzbach, Luca D.; Schusser, Benjamin; Kaufer, Benedikt B.
Multivalent Bacteria Binding by Flexible Polycationic Microsheets Matching Their Surface Charge Density
ADVANCED MATERIALS INTERFACES
IF4.4
2020-06-1710
OAAI
Ahmed, Rameez; Vaishampayan, Ankita; Cuellar-Camacho, Jose Luis; Wight, Darren J.; Donskyi, Ievgen; Unger, Wolfgang; Grohmann, Elisabeth; Haag, Rainer; Wagner, Olaf
Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration
PLOS PATHOGENS
IF4.9
2020-04-2211
OAAI
Gilbert-Girard, Shella; Gravel, Annie; Collin, Vanessa; Wight, Darren J.; Kaufer, Benedikt B.; Lazzerini-Denchi, Eros; Flamand, Louis
Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A
FRONTIERS IN MICROBIOLOGY
IF4.5
2019-06-2621
OAAI
Saviola, Anthony J.; Zimmermann, Cosima; Mariani, Michael P.; Signorelli, Sylvia A.; Gerrard, Diana L.; Boyd, Joseph R.; Wight, Darren J.; Morissette, Guillaume; Gravel, Annie; Dubuc, Isabelle; Flamand, Louis; Kaufer, Benedikt B.; Frietze, Seth
The Role of Marek's Disease Virus UL12 and UL29 in DNA Recombination and the Virus Lifecycle
VIRUSES-BASEL
IF3.5
2019-01-289
OAAI
Previdelli, Renato L.; Bertzbach, Luca D.; Wight, Darren J.; Vychodil, Tereza; You, Yu; Arndt, Sina; Kaufer, Benedikt B.
Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration

人类疱疹病毒6A的病毒蛋白U41和U70对于端粒整合是必不可少的

VIRUSES-BASEL
IF3.5
2018-11-2116
OAAI
Wight, Darren J.; Wallaschek, Nina; Sanyal, Anirban; Weller, Sandra K.; Flamand, Louis; Kaufer, Benedikt B.
The ND10 Complex Represses Lytic Human Herpesvirus 6A Replication and Promotes Silencing of the Viral Genome
VIRUSES-BASEL
IF3.5
2018-07-2910
OAAI
Sanyal, Anirban; Wallaschek, Nina; Glass, Mandy; Flamand, Louis; Wight, Darren J.; Kaufer, Benedikt B.
A Novel Antimicrobial Coating Represses Biofilm and Virulence-Related Genes in Methicillin-Resistant Staphylococcus aureus

一种新型抗菌涂层抑制耐甲氧西林金黄色葡萄球菌的生物膜和毒力相关基因

FRONTIERS IN MICROBIOLOGY
IF4.5
2018-02-1537
OAAI
Vaishampayan, Ankita; de Jong, Anne; Wight, Darren J.; Kok, Jan; Grohmann, Elisabeth
Telomeres and Telomerase: Role in Marek's Disease Virus Pathogenesis, Integration and Tumorigenesis
VIRUSES-BASEL
IF3.5
2017-07-0425
OAAI
Kheimar, Ahmed; Previdelli, Renato L.; Wight, Darren J.; Kaufer, Benedikt B.
The N-Terminus of Murine Leukaemia Virus p12 Protein Is Required for Mature Core Stability
PLOS PATHOGENS
IF4.9
2014-10-3010
OAAI
Wight, Darren J.; Boucherit, Virginie C.; Wanaguru, Madushi; Elis, Efrat; Hirst, Elizabeth M. A.; Li, Wilson; Ehrlich, Marcelo; Bacharach, Eran; Bishop, Kate N.
Molecular Model of Prion Transmission to Humans
EMERGING INFECTIOUS DISEASES
IF6.6
2009-12-0128
OAAI
Jones, Michael; Wight, Darren; Barron, Rona; Jeffrey, Martin; Manson, Jean; Prowse, Christopher; Ironside, James W.; Head, Mark W.
An Antibody to the Aggregated Synthetic Prion Protein Peptide (PrP106-126) Selectively Recognizes Disease-Associated Prion Protein (PrPSc) from Human Brain Specimens
BRAIN PATHOLOGY
IF6.2
2009-03-0515
OAAI
Jones, Michael; Wight, Darren; McLoughlin, Victoria; Norrby, Katherine; Ironside, James W.; Connolly, John G.; Farquhar, Christine F.; MacGregor, Ian R.; Head, Mark W.

研究方向

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B
Benedikt B. Kaufer
H 指数:38论文数:196被引数:4,917
L
Louis Flamand
H 指数:50论文数:189被引数:7,683
G
Giulia Aimola
H 指数:7论文数:13被引数:260
J
Joshua A. Hill
H 指数:45论文数:224被引数:9,421
A
Amr Aswad
H 指数:14论文数:21被引数:683
M
M. G. K. Jones
H 指数:61论文数:822被引数:1.6万
J
James W. Ironside
H 指数:91论文数:751被引数:3.8万
A
Alexander L. Greninger
H 指数:74论文数:665被引数:2.4万
M
Mark Head
H 指数:48论文数:284被引数:8,622
C
Cosima Zimmermann
H 指数:7论文数:11被引数:420