未登录 Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant Carmody, Patrick J.; Roushar, Francis J.; Tedman, Austin; Wang, Wei; Herwig, Madeline; Kim, Minsoo; McDonald, Eli F.; Noguera, Karen; Wong-Roushar, Jennifer; Poirier, Jon-Luc; Zelt, Nathan B.; Pockrass, Ben T.; McKee, Andrew G.; Kuntz, Charles P.; Raju, S. Vamsee; Plate, Lars; Penn, Wesley D.; Schlebach, Jonathan P. 分享 收藏
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer Wallace-Povirk, Adrianne; O'Connor, Carrie; Dekhne, Aamod S.; Bao, Xun; Nayeen, Md. Junayed; Schneider, Mathew; Katinas, Jade M.; Wong-Roushar, Jennifer; Kim, Seongho; Polin, Lisa; Li, Jing; Back, Jessica B.; Dann, Charles E.; Gangjee, Aleem; Hou, Zhanjun; Matherly, Larry H. 分享 收藏
Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy (vol 18, pg 1787, 2019) Dekhne, Aamod S.; Shah, Khushbu; Ducker, Gregory S.; Katinas, Jade M.; Wong-Roushar, Jennifer; Nayeen, Md. Junayed; Doshi, Arpit; Ning, Changwen; Bao, Xun; Fruhauf, Josephine; Liu, Jenney; Wallace-Povirk, Adrianne; O'Connor, Carrie; Dzinic, Sijana H.; White, Kathryn; Kushner, Juiwanna; Kim, Seongho; Huttemann, Maik; Polin, Lisa; Rabinowitz, Joshua D.; Li, Jing; Hou, Zhanjun; Dann, Charles E., III; Gangjee, Aleem; Matherly, Larry H. 分享 收藏
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Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoi- midazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors Wallace-Povirk, Adrianne; Tong, Nian; Wong-Roushar, Jennifer; O'Connor, Carrie; Zhou, Xilin; Hou, Zhanjun; Bao, Xun; Garcia, Gloria E.; Li, Jing; Kim, Seongho; Dann, Charles E., III; Matherly, Larry H.; Gangjee, Aleem 分享 收藏
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy Dekhne, Aamod S.; Shah, Khushbu; Ducker, Gregory S.; Katinas, Jade M.; Wong-Roushar, Jennifer; Nayeen, Md Junayed; Doshi, Arpit; Ning, Changwen; Bao, Xun; Fruhauf, Josephine; Liu, Jenney; Wallace-Povirk, Adrianne; O'Connor, Carrie; Dzinic, Sijana H.; White, Kathryn; Kushner, Juiwanna; Kim, Seongho; Huttemann, Maik; Polin, Lisa; Rabinowitz, Joshua D.; Li, Jing; Hou, Zhanjun; Dann, Charles E., III; Gangjee, Aleem; Matherly, Larry H. 分享 收藏
Targeting mitochondrial and cytosolic one carbon metabolism of pancreatic adenocarcinoma via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2-d]pyrimidine analogs Ning, Changwen; Dekhne, Aamod; Nayeen, Md. Junayed; Katinas, Jade M.; Wong, Jennifer; Fruhauf, Josephine; Bao, Xun; O'Connor, Carrie; Wallace-Povirk, Adrianne; Li, Jing; Dann, Charles E.; Gangjee, Aleem; Matherly, Larry H.; Hou, Zhanjun 分享 收藏
Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2-d]pyrimidine antifolates Dekhne, Aamod; Shah, Khushbu; Ducker, Gregory S.; Nayeen, Md. Junayed; Katinas, Jade M.; Wong, Jennifer; Doshi, Arpit; Bao, Xun; Kalpage, Hasini; Liu, Jenney; Kim, Seongho; Wallace-Povirk, Adrianne; Ning, Changwen; O'Connor, Carrie; Hou, Zhanjun; Polin, Lisa; Li, Jing; Huttemann, Maik; Rabinowitz, Joshua D.; Dann, Charles E.; Gangjee, Aleem; Matherly, Larry 分享 收藏
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Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis Golani, Lalit K.; Wallace-Povirk, Adrianne; Deis, Siobhan M.; Wong, Jennifer; Ke, Jiyuan; Gu, Xin; Raghavan, Sudhir; Wilson, Mike R.; Li, Xinxin; Poling, Lisa; de Waal, Parker W.; White, Kathryn; KushnerP, Juiwanna; O'Connor, Carrie; Hou, Zhanjun; Xu, H. Eric; Melcher, Karsten; Dann, Charles E., III; Matherly, Larry H.; Gangjee, Aleem 分享 收藏
Allosteric Opening of the Polypeptide-Binding Site When an Hsp70 Binds ATP Liu, Qinglian; Qi, Ruifeng; Sarbeng, Evans; Liu, Qun; Le, Katherine; Xu, Xinping; Xu, Hongya; Yang, Jiao; Wong, Jennifer; Vorvis, Christina; Hendrickson, Wayne; Zhou, Lei 分享 收藏
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A randomized controlled trial of coiled versus straight swan-neck Tenckhoff catheters in peritoneal dialysis patients 腹膜透析患者盘绕与直天鹅颈Tenckhoff导管的随机对照试验 Johnson, David W.; Wong, Jennifer; Wiggins, Kathryn J.; Kirwan, Robyn; Griffin, Anthony; Preston, John; Wall, Daryl; Campbell, Scott B.; Isbel, Nicole M.; Mudge, David W.; Hawley, Carmel M.; Nicol, David L. 分享 收藏
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