Juliette Legler - Publications, H-index & Citations

Juliette Legler

Utrecht University

53H指数

236论文数

1.2W被引数

收录论文 99

发表时间

Integrative multi-omic analysis reveals epigenetic and neurotransmitter signaling disruption induced by tributyltin in zebrafish eleutheroembryos 整合多组学分析揭示了三丁基锡在斑马鱼囊胚期胚胎中诱导的表观遗传和神经递质信号紊乱

Environmental Epigenetics

IF3.2

2026-09-24

OAAI

Albert Menendez-Pedriza; Janan Gawra; Jorke H Kamstra; Melissa Faria; Marina Bellot; Cristian Gòmez-Canela; Demetrio Raldúa; Juliette Legler; Joaquim Jaumot; Benjamin Piña; Laia Navarro-Martín

Assessment of the obesogenic properties of PFAS using an in vitro-based testing strategy 采用体外测试策略评估PFAS的致肥胖特性

Regulatory Toxicology and Pharmacology

IF3.5

2026-09-01

PREAI

Lentz, Sander B. I.; Bil, Wieneke; Bokkers, Bas G. H.; van Merode, Kristel; Kamstra, Jorke H.; Legler, Juliette

O-QT assistant: a multi-agent AI system for streamlined chemical hazard assessment and read-across analysis using the OECD QSAR toolbox API O-QT assistant：一个利用OECD QSAR toolbox API实现化学危害评估和读跨分析流程化的多智能体AI系统

Computational Toxicology

IF2.9

2025-12-08

OAAI

Ivo Djidrovski; Raymond Pieters; Juliette Legler; Marc Teunis

A Review of Toxicological and Exposure Data on Polymeric Antioxidant By-products 关于聚合物抗氧化剂副产物的毒理学与暴露数据综述

Reviews of Environmental Contamination and Toxicology

IF6.6

2025-10-14

OAAI

Heeteak Kang; Erik K. Rushton; Juliette Legler; Remco H. S. Westerink

Induction of human cytochrome P450 enzymes activity by metabolism disrupting chemicals in the human hepatic cell line HepaRG 代谢紊乱化学物质对人肝细胞系HepaRG中人类细胞色素P450酶活性的诱导

Toxicology

IF4.6

2025-10-09

OAAI

Elodie Person; Nicolas J Cabaton; Laurie Urien; Marlène Z Lacroix; Jorke H Kamstra; Louisa Mediouni; Barbara Kubickova; Agnès Jamin; Sylvie Chevolleau; Sebastian Hoffmann; Juliette Legler; Miriam N Jacobs; Daniel Zalko

The effects of acute and chronic exposure to bisphenols and PFAS on neuronal activity and network development 急性与慢性暴露于双酚类和PFAS对神经元活动及网络发育的影响

Science of The Total Environment

IF8

2025-08-09

OAAI

Lennart V.J. van Melis; Arjuna R. Persad; Anneloes M. Peerdeman; Manon J.H. van Rossum; Regina G.D.M. van Kleef; J. Pepijn Wopken; Juliette Legler; Remco H.S. Westerink

Exposure to organophosphate flame retardants and phthalates alters neuronal activity and network development 暴露于有机磷阻燃剂和邻苯二甲酸酯会改变神经元活动及网络发育

TOXICOLOGY

IF4.6

2025-05-13

OAAI

van Melis, Lennart V. J.; Zimnik, Kyra N.; Persad, Arjuna R.; Bak, Teije; van Rossum, Manon J. H.; van Kleef, Regina G. D. M.; Wopken, J. Pepijn; Legler, Juliette; Westerink, Remco H. S.

A computational dynamic systems model for in silico prediction of neural tube closure defects 一种用于体外预测神经管闭合缺陷的计算动态系统模型

CURRENT RESEARCH IN TOXICOLOGY

IF3

2025-01-01

OAAI

Job H. Berkhout; James A. Glazier; Aldert H. Piersma; Julio M. Belmonte; Juliette Legler; Richard M. Spencer; Thomas B. Knudsen; Harm J. Heusinkveld

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2024-08-01

OAAI

Beausoleil, Claire; Thebault, Anne; Andersson, Patrik; Cabaton, Nicolas J.; Ermler, Sibylle; Fromenty, Bernard; Garoche, Clementine; Griffin, Julian L.; Hoffmann, Sebastian; Kamstra, Jorke H.; Kubickova, Barbara; Lenters, Virissa; Kos, Vesna Munic; Poupin, Nathalie; Remy, Sylvie; Sapounidou, Maria; Zalko, Daniel; Legler, Juliette; Jacobs, Miriam N.; Rousselle, Christophe

The Virtual Human Platform for Safety Assessment (VHP4Safety) Project: Next Generation Chemical Safety Assessment Based on Human Data 安全评估虚拟人平台（VHP4Safety）项目：基于人类数据的下一代化学安全评估

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION

IF5.8

2024-01-01

OAAI

Kienhuis, A; Krul, C; van Engelen, J; Evelo, CT; Hessel, E; Hoekman, J; Kramer, N; Krop, E; Masereeuw, R; Moors, E; Negro, SO; Piersma, AH; Pieters, R; Teunis, M; Willighagen, EL; Legler, J

An adverse outcome pathway for chemical-induced Parkinson's disease: Calcium is key

NEUROTOXICOLOGY

IF3.9

2023-12-01

OAAI

Meerman, Julia J.; Legler, Juliette; Piersma, Aldert H.; Westerink, Remco H. S.; Heusinkveld, Harm J.

A vision for safer food contact materials: Public health concerns as drivers for improved testing 更安全的食品接触材料的愿景: 公共卫生问题是改进测试的驱动力

ENVIRONMENT INTERNATIONAL

IF9.7

2023-10-01

OAAI

Muncke, Jane; Andersson, Anna-Maria; Backhaus, Thomas; Belcher, Scott M.; Boucher, Justin M.; Almroth, Bethanie Carney; Collins, Terrence J.; Geueke, Birgit; Groh, Ksenia J.; Heindel, Jerrold J.; von Hippel, Frank A.; Legler, Juliette; Maffini, Maricel V.; Martin, Olwenn V.; Myers, John Peterson; Nadal, Angel; Nerin, Cristina; Soto, Ana M.; Trasande, Leonardo; Vandenberg, Laura N.; Wagner, Martin; Zimmermann, Lisa; Zoeller, R. Thomas; Scheringer, Martin

The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models

TOXICOLOGY

IF4.6

2023-02-01

OAAI

Proenca, Susana; van Sabben, Nick; Legler, Juliette; Kamstra, Jorke H.; Kramer, Nynke I.

Experimental human placental models for studying uptake, transport and toxicity of micro- and nanoplastics

SCIENCE OF THE TOTAL ENVIRONMENT

IF8

2023-02-01

OAAI

Dusza, Hanna M.; van Boxel, Jeske; van Duursen, Majorie B. M.; Forsberg, Markus M.; Legler, Juliette; Vahakangas, Kirsi H.

Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

MOLECULES

IF4.6

2023-01-07

OAAI

Bouwmeester, Manon C.; Tao, Yu; Proenca, Susana; van Steenbeek, Frank G.; Samsom, Roos-Anne; Nijmeijer, Sandra M.; Sinnige, Theo; van der Laan, Luc J. W.; Legler, Juliette; Schneeberger, Kerstin; Kramer, Nynke I.; Spee, Bart

Uptake, Transport, and Toxicity of Pristine and Weathered Micro- and Nanoplastics in Human Placenta Cells

ENVIRONMENTAL HEALTH PERSPECTIVES

IF9.8

2022-09-01

OAAI

Dusza, Hanna M.; Katrukha, Eugene A.; Nijmeijer, Sandra M.; Akhmanova, Anna; Vethaak, A. Dick; Walker, Douglas I.; Legler, Juliette

Identification of known and novel nonpolar endocrine disruptors in human amniotic fluid

ENVIRONMENT INTERNATIONAL

IF9.7

2022-01-01

OAAI

Dusza, Hanna M.; Manz, Katherine E.; Pennell, Kurt D.; Kanda, Rakesh; Legler, Juliette

Interspecies Differences in Activation of Peroxisome Proliferator-Activated Receptor γ by Pharmaceutical and Environmental Chemicals

ENVIRONMENTAL SCIENCE & TECHNOLOGY

IF11.3

2021-11-29

OAAI

Garoche, Clementine; Boulahtouf, Abdelhay; Grimaldi, Marina; Chiavarina, Barbara; Toporova, Lucia; den Broeder, Marjo J.; Legler, Juliette; Bourguet, William; Balaguer, Patrick

Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study 3T3-L1前脂肪细胞模型系统对代谢破坏化学物质的成脂反应的可重复性: 实验室间研究

TOXICOLOGY

IF4.6

2021-09-01

OAAI

Kassotis, Christopher D.; Hoffman, Kate; Volker, Johannes; Pu, Yong; Veiga-Lopez, Almudena; Kim, Stephanie M.; Schlezinger, Jennifer J.; Bovolin, Patrizia; Cottone, Erika; Saraceni, Astrid; Scandiffio, Rosaria; Atlas, Ella; Leingartner, Karen; Krager, Stacey; Tischkau, Shelley A.; Ermler, Sibylle; Legler, Juliette; Chappell, Vesna A.; Fenton, Suzanne E.; Mesmar, Fahmi; Bondesson, Maria; Fernandez, Mariana F.; Stapleton, Heather M.

Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells

COMMUNICATIONS BIOLOGY

IF5.1

2021-02-15

OAAI

Crespo, Diego; Assis, Luiz H. C.; Zhang, Yu Ting; Safian, Diego; Furmanek, Tomasz; Skaftnesmo, Kai Ove; Norberg, Birgitta; Ge, Wei; Choi, Yung-Ching; den Broeder, Marjo J.; Legler, Juliette; Bogerd, Jan; Schulz, Rudiger W.

研究方向