Alan Mackay‐Sim - Publications, H-index & Citations

Alan Mackay‐Sim

griﬃth university

71H指数

359论文数

1.9W被引数

收录论文 79

发表时间

Leveraging inertial sensors and dynamic time warping to identify biomarkers for gait impairment in hereditary spastic paraplegia: an exploratory study 利用惯性传感器和动态时间规整识别遗传性痉挛性截瘫痛步态障碍的生物标志物：一项探索性研究

Scientific Reports

IF3.9

2026-07-28

OAAI

Luis De Sousa-De Sousa; Matthew T. O. Worsey; Will Sutton; Hugo G. Espinosa; David Rowlands; David V. Thiel; Pablo García-Fernández; Frank McKeown; Alan Mackay-Sim

Convergent effects of synthetic glucocorticoid dexamethasone and amyloid beta in human olfactory neurosphere-derived cells 合成糖皮质激素地塞米松和β-淀粉样蛋白在人类嗅觉神经球源性细胞中的趋同效应

JOURNAL OF NEUROCHEMISTRY

IF4

2024-11-18

OAAI

Farnum, Zane; Mani, Radhika; Bindoff, Aidan; Wilson, Richard; Fiotakis, Adoni; Stephens, Jessica; Cho, Ellie; Mackay-Sim, Alan

Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress

NEUROBIOLOGY OF DISEASE

IF5.6

2024-09-01

OAAI

Leeson, Hannah C.; Aguado, Julio; Gomez-Inclan, Cecilia; Chaggar, Harman Kaur; Fard, Atefah Taherian; Hunter, Zoe; Lavin, Martin F.; Mackay-Sim, Alan; Wolvetang, Ernst J.

Reduced acetylated α-tubulin in SPAST hereditary spastic paraplegia patient PBMCs

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-03-28

OAAI

Wali, Gautam; Siow, Sue-Faye; Liyanage, Erandhi; Kumar, Kishore R. R.; Mackay-Sim, Alan; Sue, Carolyn M. M.

An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition

CELLS

IF5.2

2022-10-17

OAAI

Rantanen, Laura M.; Bitar, Maina; Lampinen, Riikka; Stewart, Romal; Quek, Hazel; Oikari, Lotta E.; Cuni-Lopez, Carla; Sutharsan, Ratneswary; Thillaiyampalam, Gayathri; Iqbal, Jamila; Russell, Daniel; Penttila, Elina; Lopponen, Heikki; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Koivisto, Anne M.; Haupt, Larisa M.; Mackay-Sim, Alan; Cristino, Alexandre S.; Kanninen, Katja M.; White, Anthony R.

Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer's Disease Patients 阿尔茨海默病患者嗅觉黏膜细胞的单细胞rna-seq分析

CELLS

IF5.2

2022-02-15

OAAI

Lampinen, Riikka; Fazaludeen, Mohammad Feroze; Avesani, Simone; Ord, Tiit; Penttila, Elina; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Saveleva, Liudmila; Kaartinen, Emma; Fernandez Acosta, Francisco; Cruz-Haces, Marcela; Lopponen, Heikki; Mackay-Sim, Alan; Kaikkonen, Minna U.; Koivisto, Anne M.; Malm, Tarja; White, Anthony R.; Giugno, Rosalba; Chew, Sweelin; Kanninen, Katja M.

Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids 抑制cgas-sting途径可改善共济失调-毛细血管扩张症脑类器官的过早衰老标志

AGING CELL

IF7.1

2021-08-30

OAAI

Aguado, Julio; Chaggar, Harman K.; Gomez-Inclan, Cecilia; Shaker, Mohammed R.; Leeson, Hannah C.; Mackay-Sim, Alan; Wolvetang, Ernst J.

Single cell morphology distinguishes genotype and drug effect in Hereditary Spastic Paraplegia

SCIENTIFIC REPORTS

IF3.9

2021-08-17

OAAI

Wali, Gautam; Berkovsky, Shlomo; Whiten, Daniel R.; Mackay-Sim, Alan; Sue, Carolyn M.

Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype 与肌萎缩侧索硬化风险和临床表型相关的新型STMN2变体

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2021-03-26

OAAI

Theunissen, Frances; Anderton, Ryan S.; Mastaglia, Frank L.; Flynn, Loren L.; Winter, Samantha J.; James, Ian; Bedlack, Richard; Hodgetts, Stuart; Fletcher, Sue; Wilton, Steve D.; Laing, Nigel G.; MacShane, Mandi; Needham, Merrilee; Saunders, Ann; Mackay-Sim, Alan; Melamed, Ze'ev; Ravits, John; Cleveland, Don W.; Akkari, P. Anthony

Mitochondrial Function in Hereditary Spastic Paraplegia: Deficits in SPG7 but Not SPAST Patient-Derived Stem Cells

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-08-20

OAAI

Wali, Gautam; Kumar, Kishore Raj; Liyanage, Erandhi; Davis, Ryan L.; Mackay-Sim, Alan; Sue, Carolyn M.

Antibody-Free Targeted Proteomics Assay for Absolute Measurement of α-Tubulin Acetylation

ANALYTICAL CHEMISTRY

IF6.7

2020-07-08

PREAI

Shah, Alok K.; Wali, Gautam; Sue, Carolyn M.; Mackay-Sim, Alan; Hill, Michelle M.

Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

PARTICLE AND FIBRE TOXICOLOGY

IF8.2

2020-06-01

OAAI

Chew, Sweelin; Lampinen, Riikka; Saveleva, Liudmila; Korhonen, Paula; Mikhailov, Nikita; Grubman, Alexandra; Polo, Jose M.; Wilson, Trevor; Komppula, Mika; Ronkko, Teemu; Gu, Cheng; Mackay-Sim, Alan; Malm, Tarja; White, Anthony R.; Jalava, Pasi; Kanninen, Katja M.

Oxidative Stress-Induced Axon Fragmentation Is a Consequence of Reduced Axonal Transport in Hereditary Spastic Paraplegia SPAST Patient Neurons

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-05-07

OAAI

Wali, Gautam; Liyanage, Erandhi; Blair, Nicholas F.; Sutharsan, Ratneswary; Park, Jin-Sung; Mackay-Sim, Alan; Sue, Carolyn M.

SCHIZOPHRENIA PATIENT-DERIVED STEM CELLS FOR SYSTEMS GENOMICS: GENETIC VARIANTS, MOLECULAR PATHWAYS AND CELL FUNCTIONS ALTERED IN INDIVIDUAL PATIENTS

SCHIZOPHRENIA BULLETIN

IF4.8

2019-04-09

OAAI

Cristino, Alexandre; Tyebally, Mubarika; Sabdia, Muhammed; Thillaiyampalam, Gayathri; Mackay-Sim, Alan

DNA methylation in schizophrenia in different patient-derived cell types

NPJ SCHIZOPHRENIA

IF5.7

2017-01-23

OAAI

Vitale, Alejandra M.; Matigian, Nicholas A.; Cristino, Alexandre S.; Nones, Katia; Ravishankar, Sugandha; Bellette, Bernadette; Fan, Yongjun; Wood, Stephen A.; Wolvetang, Ernst; Mackay-Sim, Alan

Olfactory ensheathing cells but not fibroblasts reduce the duration of autonomic dysreflexia in spinal cord injured rats

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

IF3.3

2016-12-01

PREAI

Cloutier, Frank; Kalincik, Tomas; Lauschke, Jenny; Tuxworth, Gervase; Cavanagh, Brenton; Meedeniya, Adrian; Mackay-Sim, Alan; Carrive, Pascal; Waite, Phil

A Grand Challenge. 2. Phenotypic Profiling of a Natural Product Library on Parkinson's Patient-Derived Cells

JOURNAL OF NATURAL PRODUCTS

IF3.6

2016-07-22

OAAI

Vial, Marie-Laure; Zencak, Dusan; Grkovic, Tanja; Gorse, Alain-Dominique; Mackay-Sim, Alan; Mellick, George D.; Wood, Stephen A.; Quinn, Ronald J.

Mechanism of impaired microtubule-dependent peroxisome trafficking and oxidative stress in SPAST-mutated cells from patients with Hereditary Spastic Paraplegia

SCIENTIFIC REPORTS

IF3.9

2016-05-27

OAAI

Wali, Gautam; Sutharsan, Ratneswary; Fan, Yongjun; Stewart, Romal; Velasquez, Johana Tello; Sue, Carolyn M.; Crane, Denis I.; Mackay-Sim, Alan

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients

TRANSLATIONAL PSYCHIATRY

IF6.2

2015-10-20

OAAI

Topol, A.; English, J. A.; Flaherty, E.; Rajarajan, P.; Hartley, B. J.; Gupta, S.; Desland, F.; Zhu, S.; Goff, T.; Friedman, L.; Rapoport, J.; Felsenfeld, D.; Cagney, G.; Mackay-Sim, A.; Savas, J. N.; Aronow, B.; Fang, G.; Zhang, B.; Cotter, D.; Brennand, K. J.

Reduced protein synthesis in schizophrenia patient-derived olfactory cells

TRANSLATIONAL PSYCHIATRY

IF6.2

2015-10-20

OAAI

English, J. A.; Fan, Y.; Foecking, M.; Lopez, L. M.; Hryniewiecka, M.; Wynne, K.; Dicker, P.; Matigian, N.; Cagney, G.; Mackay-Sim, A.; Cotter, D. R.

研究方向