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T

Tobias M.P. Hartwich

Yale University

13H指数
105论文数
1.0K被引数
收录论文 27
发表时间
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Whole-Exome Sequencing Identifies Candidate Genomic Features Associated with Response to Platinum-Based Chemotherapy and Ixabepilone-Based Treatment in Ovarian Cancer全外显子组测序鉴定与卵巢癌对铂类和伊沙匹隆为基础的治疗反应相关的候选基因组特征
errInternational Journal of Molecular Sciences
IF4.9
err2026-08-31
err0
errOAAI
errTobias M. P. Hartwich; Stefania Bellone; Orazio De Tommasi; Sarah Ottum; Victoria Ettorre; Michelle Greenman; Namrata Sethi; Cem Demirkiran; Kevin Y. Yang; Ammal Abbasi; Ludmil B. Alexandrov; Alessandro D. Santin
err分享
err收藏
Integrated expression profiling of trophoblast cell-surface antigen 2 (TROP2), folate receptor alpha (FRα), and human epidermal growth factor receptor 2 (HER2) in endometrial Cancer across molecular classes, genomic alterations, and histologic subtypes子宫内膜癌中滋养层细胞表面抗原2（TROP2）、叶酸受体α（FRα）和人类表皮生长因子受体2（HER2）的整合表达谱分析，涉及分子类别、基因组改变和组织学亚型
errGynecologic Oncology
IF4.1
err2026-08-01
err0
PREAI
errDe Tommasi, Orazio; Palmieri, Luca; Bellone, Stefania; Buza, Natalia; Sethi, Namrata; Ottum, Sarah; Demirkiran, Cem; Hui, Pei; Sun, Tong; Niu, Na; Ettorre, Victoria M.; Hartwich, Tobias M. P.; Tozzi, Roberto; Santin, Alessandro D.
err分享
err收藏
Identification of Maternal Serum Longitudinal Signatures Through Profiling of 96 Cytokines通过96种细胞因子的谱分析鉴定母体血清纵向特征
errLife
IF3.4
err2026-04-22
err0
errOAAI
errViktoriia Kolesnyk; Colleen Sinnott; Tobias Max Philipp Hartwich; Foram Gandhi; Jennifer Culhane; Lisbet Lundsberg; Sonya Abdel-Razeq; Miranda Mansolf; Samantha Novo; Olga Grechukhina; Yang Yang-Hartwich
err分享
err收藏
Folate receptor alpha as a successful biomarker in the treatment of low grade serous ovarian cancer patients using preclinical and clinical models叶酸受体α作为低级别浆液性卵巢癌患者治疗中成功的生物标志物，通过预临床和临床模型进行研究。
errInternational Journal of Gynecological Cancer
IF4.7
err2025-11-08
err0
PREAI
errVictoria M. Ettorre; Beatrice Conca; Cem Demirkiran; Stefania Bellone; Namrata Sethi; Tobias Max Philipp Hartwich; Na Niu; Natalia Buza; Roberto Angioli; Francesco Plotti; Luca Palmieri; Alessandro D. Santin
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err收藏
Antibody Generation Using Cancer-Derived Small Extracellular Vesicles (sEVs): A Platform for Targeted Cancer Therapy and Potential Personalized Applications利用癌症来源的小型外泌体（sEVs）生成抗体：一种靶向癌症治疗和潜在个性化应用的平台
errSMALL
IF12.1
err2025-11-01
err0
PREAI
errFirouzi, Maryam; Kang, Changsun; Ren, Xiaoyu; Jung, Woncheol; Abushukair, Hassan; Hartwich, Tobias M. P.; Ramesh, Rajagopal; Yoon, Je-Hyun; Yang-Hartwich, Yang; Oh, Tae Gyu; Kim, Dongin
err分享
err收藏
Immunohistochemistry, next generation sequencing (NGS), and whole exome sequencing concordance in HER2 testing in uterine serous carcinoma: a retrospective analysis免疫组织化学、下一代测序(NGS)和全外显子组测序在子宫浆液性癌HER2检测中的符合率：一项回顾性分析
errGynecologic Oncology
IF3.7
err2025-10-14
err0
PREAI
errVictoria M. Ettorre; Stefania Bellone; Natalia Buza; Pei Hui; Tobias Max Philipp Hartwich; Cem Demirkiran; Michelle Greenman; Namrata Sethi; Luca Palmieri; Alessandro D. Santin
err分享
err收藏
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancersIDR诱导的CAR凝聚体提高了CAR-Ts对低抗原癌症的细胞毒性
errNature Chemical Biology
IF13.7
err2025-09-29
err0
errOAAI
errXinyan Zhang; Qian Xiao; Longhui Zeng; Fawzaan Hashmi; Kazuki Sato; Tobias Max Philipp Hartwich; Miranda Mansolf; Yang Yang-Hartwich; Xiaolei Su
err分享
err收藏
Preclinical Efficacy of the Estrogen Receptor Degrader Fulvestrant in Combination with RAF/MEK Clamp Avutometinib and FAK Inhibitor in a Low-Grade Serous Ovarian Cancer Animal Model with Acquired Resistance to Chemotherapy and Aromatase Inhibitor雌激素受体降解剂Fulvestrant与RAF/MEK夹具Avutometinib及FAK抑制剂联合应用在低级别浆液性卵巢癌动物模型中的预临床疗效（该模型对化疗和芳香化酶抑制剂产生获得性耐药）
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 8924
IF4.9
err2025-09-21
err0
errOAAI
errCem Demirkiran; Stefania Bellone; Victoria M. Ettorre; Miranda Mansolf; Tobias Max Philipp Hartwich; Blair McNamara; Michelle Greenman; Yang Yang-Hartwich; Elena Ratner; Niccoló G. Santin; Namrata Sethi; Luca Palmieri; Silvia Coma; Jonathan A. Pachter; Sarah Ottum; Alessandro D. Santin
err分享
err收藏
Effective preclinical activity of datopotamab deruxtecan (Dato-DXd), an ADC targeting trophoblast cell-surface antigen 2 (TROP2), against primary cervical carcinoma cell lines and xenografts达波妥昔单抗德鲁克坦（Dato-DXd）是一种靶向滋养层细胞表面抗原2（TROP2）的抗体药物偶联物（ADC），其对原代宫颈癌细胞系和异种移植瘤表现出有效的临床前活性。
errgynecologic oncology
IF4.1
err2025-09-03
err0
PREAI
errVictoria M. Ettorre; Cem Demirkiran; Stefania Bellone; Tobias Max Philipp Hartwich; Michelle Greenman; Blair McNamara; Namrata Sethi; Luca Palmieri; Alessandro D. Santin
err分享
err收藏
Datopotamab deruxtecan, a novel TROP2-tareting antibody-drug conjugate with a topoisomerase I inhibitor payload, shows preclinical activity against primary and metastatic uterine and ovarian TROP2 over-expressing carcinosarcomaDatopotamab deruxtecan，一种靶向TROP2的新型抗体偶联药物，其载荷为拓扑异构酶I抑制剂，在体外显示出对原发性及转移性子宫和卵巢TROP2过表达的癌肉瘤的活性。
errgynecologic oncology
IF4.1
err2025-06-28
err0
PREAI
errMichelle Greenman; Stefania Bellone; Cem Demirkiran; Tobias Max Philipp Hartwich; Victoria M. Ettorre; Blair McNamara; Namrata Sethi; Niccolo G. Santin; Luca Palmieri; Yang Yang-Hartwich; Elena Ratner; Alessandro D. Santin
err分享
err收藏
Preclinical activity of sacituzumab govitecan in TROP2-positive low-grade serous ovarian cancer patient-derived xenograft models沙西妥珠单抗 govitecan 在 TROP2 阳性低级别浆液性卵巢癌患者来源异种移植模型中的临床前活性
errInternational Journal of Gynecological Cancer
IF4.7
err2025-06-25
err0
PREAI
errVictoria M. Ettorre; Cem Demirkiran; Stefania Bellone; Na Niu; Natalia Buza; Namrata Sethi; Tobias Max Philipp Hartwich; Luca Palmieri; Alessandro D. Santin
err分享
err收藏
Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2
errCLINICAL & EXPERIMENTAL METASTASIS
IF3.2
err2024-06-22
err0
PREAI
errMutlu, Levent; McNamara, Blair; Bellone, Stefania; Manavella, Diego D.; Demirkiran, Cem; Greenman, Michelle; Verzosa, Miguel Skyler Z.; Buza, Natalia; Hui, Pei; Hartwich, Tobias Max Philipp; Harold, Justin; Yang-Hartwich, Yang; Zipponi, Margherita; Altwerger, Gary; Ratner, Elena; Huang, Gloria S.; Clark, Mitchell; Andikyan, Vaagn; Azodi, Masoud; Schwartz, Peter E.; Santin, Alessandro D.
err分享
err收藏
Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-16
err1
PREAI
errBellone, Stefania; Jeong, Kyungjo; Halle, Mari Kylleso; Krakstad, Camilla; Mcnamara, Blair; Greenman, Michelle; Mutlu, Levent; Demirkiran, Cem; Hartwich, Tobias Max Philipp; Yang-Hartwich, Yang; Zipponi, Margherita; Buza, Natalia; Hui, Pei; Raspagliesi, Francesco; Lopez, Salvatore; Paolini, Biagio; Milione, Massimo; Perrone, Emanuele; Scambia, Giovanni; Altwerger, Gary; Ravaggi, Antonella; Bignotti, Eliana; Huang, Gloria S.; Andikyan, Vaagn; Clark, Mitchell; Ratner, Elena; Azodi, Masoud; Schwartz, Peter E.; Quick, Charles M.; Angioli, Roberto; Terranova, Corrado; Zaidi, Samir; Nandi, Shuvro; Alexandrov, Ludmil B.; Siegel, Eric R.; Choi, Jungmin; Schlessinger, Joseph; Santin, Alessandro D.
err分享
err收藏
A Benzenesulfornamide with potential to improve chemoresponse of ovarian cancer through activation of AMPK and immunogenic cell death
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errKim, Juhyun; Montero, Nia; Sharma, Shefali; Mansolf, Miranda; Yang, Kevin; Hartwich, Tobias; Yang-Hartwich, Yang
err分享
err收藏
Identification of SORL1 as a key regulator of chemoresistance in ovarian cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errMansolf, Miranda; Jian, Ziyan; Bi, Fangfang; Hartwich, Tobias M.; Yang-Hartwich, Yang
err分享
err收藏
In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-09-07
err1
PREAI
errMutlu, Levent; Manavella, Diego D.; Bellone, Stefania; Mcnamara, Blair; Harold, Justin A.; Mauricio, Dennis; Siegel, Eric R.; Buza, Natalia; Hui, Pei; Hartwich, Tobias Max Philipp; Yang-Hartwich, Yang; Demirkiran, Cem; Verzosa, Miguel Skyler Z.; Altwerger, Gary; Ratner, Elena S.; Huang, Gloria S.; Clark, Mitchell; Andikyan, Vaagn; Azodi, Masoud; Dottino, Peter R.; Schwartz, Peter E.; Santin, Alessandro D.
err分享
err收藏
In vivo efficacy of RAF/MEK clamp avutometinib (VS-6766) in combination with FAK inhibition in low grade serous ovarian cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errMcNamara, Blair; Demirkiran, Cem; Bellone, Stefania; Mutlu, Levent; Zipponi, Margherita; Verzosa, Miguel S.; Harold, Justin; Hartwich, Tobias M.; Altwerger, Gary; Ratner, Elena; Huang, Gloria; Clark, Mitchell; Andikyan, Vaagn; Azodi, Masoud; Schwartz, Peter E.; Dottino, Peter; Santin, Alessandro D.
err分享
err收藏
Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti–PD-1 Immunotherapy in Endometrial Carcinoma
errCancer Discovery
IF33.3
err2022-10-27
err37
errOAAI
errChow, Ryan D.; Michaels, Tai; Bellone, Stefania; Hartwich, Tobias M. P.; Bonazzoli, Elena; Iwasaki, Akiko; Song, Eric; Santin, Alessandro D.
err分享
err收藏
A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2021-12-03
err6
errOAAI
errBi, Fangfang; Jiang, Ziyan; Park, Wonmin; Hartwich, Tobias M. P.; Ge, Zhiping; Chong, Kay Y.; Yang, Kevin; Morrison, Madeline J.; Kim, Dongin; Kim, Jaeyeon; Zhang, Wen; Kril, Liliia M.; Watt, David S.; Liu, Chunming; Yang-Hartwich, Yang
err分享
err收藏
Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells
errONCOGENESIS
IF6.4
err2020-05-29
err11
errOAAI
errKang, Min; Chong, Kay Yi; Hartwich, Tobias M. P.; Bi, Fangfang; Witham, Allyson K.; Patrick, David; Morrisson, Madeline J.; Cady, Sarah L.; Cerchia, Alexandra P.; Kelk, Dawn; Liu, Yifei; Nucci, Jonah; Madarikan, Oluwagbemisola; Ueno, Daiki; Shuch, Brian M.; Yang-Hartwich, Yang
err分享
err收藏

研究方向

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合作学者
合作期刊
J
Joseph Schlessinger
H 指数: 174 · 论文数: 719
A
Akiko Iwasaki
H 指数: 124 · 论文数: 611
G
Giovanni Scambia
H 指数: 117 · 论文数: 3.2K
L
Ludmil B. Alexandrov
H 指数: 96 · 论文数: 480
M
Michael W. Davidson
H 指数: 76 · 论文数: 335
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