未登录A novel CCR4 antagonist induces potent anti-tumor response through inhibition of Treg migration into the tumor microenvironment
Nair, Rashmi; Abbineni, Chandrasekhar; Talluri, Krishna Chaitanya; Dhudashiya, Amit A.; Aravind, A. B.; Kumar, Naveen R.; Ramya, R.; Balasubramanyam, D.; Obanna, Pathur; Madhaiyan, Rabin; Samiulla, D. S.; Daginakatte, Girish; Narayanan, Kishore; Nellore, Kavitha; Chelur, Shekar; Samajdar, Susanta; Ramachandra, Murali .png)
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收藏Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignanciesXiao, Lanbo; He, Tongchen; Klingbeil, Olaf; Eleanor, Young; Wu, Xiaoli; Qiao, Yuanyuan; Parolia, Abhijit; Eyunni, Sanjana; Mannan, Rahul; Mahapatra, Somnath; Kim, NamHoon; Zheng, Heng; Su, Fengyun; Cao, Xuhong; Samajdar, Susanta; Ramachandra, Murali; Vakoc, Christopher R.; Chinnaiyan, Arul M. 分享 收藏 Development of novel anti-SIRPa/ß dual antibody with single-agent phagocytosis activityChakrabarty, Subhra Prakash; Patil, Sandeep Sadashiv; Rajput, Sunaina Singh; Mukerji, Amrita; Aurumugam, Sandhya; Gade, Pooja Balu; Sidhesha, S.; Patra, Anup Kumar; Shivaranjini, C.; Khamkar, Vaishnavi Shivaji; Lavanya, P.; Lakshmeesha, K. N.; Kapoor, Ujjwal; Jagadeesh, R.; Nagaraj, Jwala; Nataraj, Vijaya Shankar; Nellore, Kavitha; Antony, Thomas; Samajdar, Susanta; Ramachandra, Murali 分享 收藏 H3.3K27M diffuse midline gliomas are sensitive to SWI/SNF chromatin remodeler degradationMota, Mateus; Sweha, Stefan; Pun, Matt; Natarajan, Siva Kumar; Ding, Yujie; Chung, Chan; Hawes, Debra; Yang, Fusheng; Judkins, Alexander; Samajdar, Susanta; Cao, Xuhong; Xiao, Lanbo; Parolia, Abhijit; Chinnaiyan, Arul; Venneti, Sriram 分享 收藏 分享 收藏 Discovery of AUR-112, a novel MALT1 protease inhibitor for the treatment of B cell lymphomasBalasubramanian, Wesley Roy; Raju, Sammeta Srinivasa; Vasantha, K. Y.; Reddy, Archana Bhumi; Maben, Janith Mary; Patil, Sandeep Sadashiv; Raghavendra, N. R.; Aithal, Kiran B.; Charamanna, K. B.; Chikkanna, Dinesh; Nellore, Kavitha; Samiulla, D. S.; Daginakatte, Girish; Chelur, Shekar; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 Potent anti-tumor activity of a selective and orally bioavailable reversible covalent CDK12 inhibitorKhare, Leena; Poddutoori, Ramulu; Mukherjee, Subhendu; Samiulla, D. S.; Devaraja, T. S.; Marappan, Sivapriya; Nayak, Shilpa; Sivakumar, Sasirekha; Kaza, Lakshmi; Tgore, Suraj; Dhudashiya, Amit; Raghavendra, N. R.; Gunnepalli, Bhargav; Aravind, A. B.; Amith, A.; Charamanna, K. B.; Antony, Thomas; Nellore, Kavitha; Daginakatte, Girish; Chelur, Shekar; Giri, Sanjeev; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 The discovery of potent KAT6 inhibitors that demonstrate anti-tumor activity in preclinical models of ER plus breast cancerPalanisamy, Gopinath S.; Venkateshappa, Chandregowda; Goyal, Megha; Barrett, Susanna A.; Heam, Brian R.; Daginakatte, Girish; Aravind, A. B.; Samiulla, D. S.; Bera, Kalisankar; Sangeetha, S.; Khare, Leena; Parisian, Alison D.; Heerding, Dirk A.; Ng, Raymond A.; Harmon, Cyrus L.; Samajdar, Susanta; Ramachandra, Murali; Myles, David C. 分享 收藏 Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with VenetoclaxGaur, Tarang; Poddutoori, Ramulu; Khare, Leena; Bagal, Bhausaheb; Rashmi, Sonal; Patkar, Nikhil; Tembhare, Prashant; Pg, Subramanian; Shetty, Dhanlaxmi; Dutt, Amit; Zhang, Qi; Konopleva, Marina; Platzbeckar, Uwe; Gupta, Sudeep; Samajdar, Susanta; Ramchandra, Murali; Khattry, Navin; Hasan, Syed K. 分享 收藏 Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas靶向H3.3K27M弥漫性内源性脑桥胶质瘤的SWI/SNF atp酶Mota, Mateus; Sweha, Stefan R.; Pun, Matt; Natarajan, Siva Kumar; Ding, Yujie; Chung, Chan; Hawes, Debra; Yang, Fusheng; Judkins, Alexander R.; Samajdar, Susanta; Cao, Xuhong; Xiao, Lanbo; Parolia, Abhijit; Chinnaiyan, Arul M.; Venneti, Sriram 分享 收藏 A highly differentiated A2AR inhibitor for potential use in cancer therapyVenkateshappa, Chandregowda; Narayanan, Kishore; Nair, Rashmi; Ab, Aravind; Putta, Ramakishore Vp; Nagaraj, Jwala; Goyal, Megha; Ahuja, Vijay Kamal; Dhudashiya, Amith A.; Ds, Samiulla; Daginakatte, Girish; Antony, Thomas; Nellore, Kavitha; Samajdar, Susanta; Ramachandra, Murali 分享 收藏 分享 收藏 Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of ActionPoddutoori, Ramulu; Aardalen, Kimberly; Aithal, Kiran; Barahagar, Sanjeev Surendranath; Belliappa, Charamanna; Bock, Mark; Chelur, Shekar; Gerken, Andrea; Gopinath, Sreevalsam; Gruenenfelder, Bjoern; Kiffe, Michael; Krishnaswami, Maithreyi; Langowski, John; Madapa, Sudharshan; Narayanan, Kishore; Pandit, Chetan; Panigrahi, Sunil Kumar; Perrone, Mark; Potakamuri, Ravi Kumar; Ramachandra, Murali; Ramanathan, Anuradha; Ramos, Rita; Sager, Emine; Samajdar, Susanta; Subramanya, Hosahalli S.; Thimmasandra, Devaraja Seethappa; Venetsanakos, Eleni; Mobitz, Henrik 分享 收藏 Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic MalignanciesGummadi, Venkateshwar Rao; Boruah, Anima; Ainan, Bharathi Raja; Vare, Brahma Reddy; Manda, Srinivas; Gondle, Hari Prakash; Kumar, Shiva Nagendra; Mukherjee, Subhendu; Gore, Suraj T.; Krishnamurthy, Narasimha Rao; Marappan, Sivapriya; Nayak, Shilpa S.; Nellore, Kavitha; Balasubramanian, Wesley Roy; Bhumireddy, Archana; Giri, Sanjeev; Gopinath, Sreevalsam; Samiulla, Dodheri S.; Daginakatte, Girish; Basavaraju, Aravind; Chelur, Shekar; Eswarappa, Rajesh; Belliappa, Charamanna; Subramanya, Hosahalli S.; Booher, Robert N.; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 Targeting cancer with selective cbp/p300 bromodomain inhibitorsJaleel, Mahaboobi; Senaiar, Ramesh S.; Abbineni, Chandrasekhar; Renukappa, Girish A.; Mukherjee, Subhendu; Marappan, Sivapriya; Samiulla, D. S.; Aravind, A. B.; Kumar, Naveen R.; Reddy, Venkata Siva N.; Babu, Asha; Srinivas, Akhila P.; Yadlapalli, Prasad; Tgore, Suraj; Raghavendra, N. R.; Naik, Chandranath D.; Giri, Sanjeev; Antony, Thomas; Nellore, Kavitha; Chelur, Shekar; Daginakatte, Girish; Ravanti, laura; Myllymaki, Mikko; Wohlfahrt, Gerd; Mattila, Elina; Karlsson, Stefan; Bjorkman, Mari; Riikonen, Reetta; Ikonen, Tarja; Leimu, Laura; Malmstrom, Chira; Korjamo, Timo; Moilanen, Anu; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 First in class orally bioavailable BETBRD degradersAbbineni, Chandrasekhar; Jaleel, Mahaboobi; Mukherjee, Subhendu; Marappan, Sivapriya; Tiwari, Nirbhay Kumar; Samiulla, D. S.; Aravind, A. B.; Kumar, Naveen R.; Bansal, Indu; Reddy, Raghurami B.; Bandaru, N. V. M. Rao; Srinivas, Akhila; Maben, Janith Mary; Tgore, Suraj; Kumar, Avainash; Nankar, Rakesh P.; Naik, Chandranath D.; Antony, Thomas; Nellore, Kavitha; Giri, Sanjeev; Daginakatte, Girish; Chelur, Shekar; Tormakangas, Olli; Wohlfahrt, Gerd; Bjorkman, Mari; Mattila, Elina; Ravanti, Laura; Moilanen, Anu; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 Anti-tumor efficacy of SMARCA degraders in pre-clinical models of cancerSatyam, Leena Khare; Sasmal, Sanjita; Pothuganti, Manoj K.; Sreevidya, M. R.; Ettam, Ashokk; Nunna, Sireesha; Roshaiah, Marla; Chithaluru, Shankaraiah; Pallepati, Rangarao; Pawar, Amitkumar A.; Narukulla, Leela P.; Sripathi, Raghunadh A.; Tgore, Suraj; Nankar, Rakesh P.; Charamanna, K. B.; Gowda, Nagesh S.; Aithal, Kiran; Samiulla, D. S.; Mukherjee, Subhendu; Chelur, Shekar; Nellore, Kavitha; Daginakatte, Girish; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 Preclinical evaluation of pharmacokinetics, pharmacodynamics and efficacy of the dual CD73-A2AR InhibitorsChikkanna, Dinesh; Narayanan, Kishore; Panigrahi, Sunil; Priyadarshini, Garima; Goyal, Megha; Mani, Jiju; Samiulla, D. S.; Dadhania, Sagar; Aravind, A. B.; Daginakatte, Girish; Anthony, Thomas; Nellore, Kavitha; Samajdar, Susanta; Ramachandra, Murali 分享 收藏 Pharmacological characterization of a preclinical candidate covalently inhibiting CDK12Poddutoori, Ramulu; Rajagopalan, Sujatha; Mukherjee, Subhendu; Marappan, Sivapriya; Samiulla, D. S.; Sivakumar, Sasirekha; Nayak, Shilpa S.; Ravindra, M., V; Devaraja, T. S.; Kondela, Srinivas; Tgore, Suraj; Dhudashiya, Amit A.; Charamanna, K. B.; Aravind, A. B.; Amith, A.; Pavithra, S.; Pathange, Hema Sankar; Antony, Thomas; Jaleel, Mahaboobi; Giri, Sanjeev; Daginakatte, Girish; Nellore, Kavitha; Chelur, Shekar; Ramachandra, Murali; Samajdar, Susanta 分享 收藏 ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityHolmstrom, Tim H.; Moilanen, Anu-Maarit; Ikonen, Tarja; Bjorkman, Mari L.; Linnanen, Tero; Wohlfahrt, Gerd; Karlsson, Stefan; Oksala, Riikka; Korjamo, Timo; Samajdar, Susanta; Rajagopalan, Srinivasan; Chelur, Shekar; Narayanan, Kishore; Ramachandra, Raghuveer K.; Mani, Jiju; Nair, Rashmi; Gowda, Nagaraj; Anthony, Thomas; Dhodheri, Samiulla; Mukherjee, Subhendu; Ujjinamatada, Ravi K.; Srinivas, Nanduri; Ramachandra, Murali; Kallio, Pekka J. 分享 收藏 
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