Christiano R. R. Alves - Publications, H-index & Citations

Christiano R. R. Alves

department of neurology

23H指数

72论文数

1.7K被引数

收录论文 31

发表时间

Profiling circulating Tau and phospho-Tau isoforms in pediatric and adult spinal muscular atrophy identifies selective elevation of pTau-262 in adults 对儿童和成人脊髓性肌萎缩症患者中循环Tau和磷酸化Tau异构体的分析，发现成人中pTau-262选择性升高

Journal of Neurology

IF4.6

2026-07-17

OAAI

Leillani L. Ha; Sunayana Mitra; Doreen T. Ho; Becky Fillingham; James D. Berry; Kathryn J. Swoboda; Christiano R. R. Alves

Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice 使用定制的CRISPR–Cas9碱基编辑器治疗小鼠中的严重血管疾病

Nature Biomedical Engineering

IF26.6

2025-09-11

PREAI

Christiano R. R. Alves; Sabyasachi Das; Vijai Krishnan; Leillani L. Ha; Lauren R. Fox; Hannah E. Stutzman; Claire E. Shamber; Pazhanichamy Kalailingam; Siobhan McCarthy; Christian L. Lino Cardenas; Claire E. Fong; Takahiko Imai; Sunayana Mitra; Shuqi Yun; Rachael K. Wood; Friederike M. C. Benning; Kangsan Roh; Joseph Lawton; Nahye Kim; Rachel A. Silverstein; Joana Ferreira da Silva; Demitri de la Cruz; Rashmi Richa; Jun Xie; Heather L. Gray-Edwards; Rajeev Malhotra; David Y. Chung; Luke H. Chao; Shengdar Q. Tsai; Casey A. Maguire; Mark E. Lindsay; Benjamin P. Kleinstiver; Patricia L. Musolino

Early life safety profiling of gene therapy for spinal muscular atrophy 脊髓性肌萎缩基因疗法的早期安全性评估

GENE THERAPY

IF4.5

2025-04-01

OAAI

Rebecca G. Spellman; Leillani L. Ha; Salomé Da Silva Duarte Lepez; Elizabeth A. Arruda; Emma Rodrigues; Kathryn J. Swoboda; Christiano R. R. Alves

Physical performance and plasma metabolic profile as potential prognostic factors in metastatic lung cancer patients

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

IF3.6

2024-07-26

OAAI

das Neves, Willian; Alves, Christiano R. R.; dos Santos, Gabriela; Alves, Maria-Janieire N. N.; Deik, Amy; Pierce, Kerry; Dennis, Courtney; Buckley, Lily; Clish, Clary B.; Swoboda, Kathryn J.; Brum, Patricia C.; de Castro Junior, Gilberto

Aerobic exercise training mitigates tumor growth and cancer-induced splenomegaly through modulation of non-platelet platelet factor 4 expression

SCIENTIFIC REPORTS

IF3.9

2023-12-11

OAAI

Tobias, Gabriel C.; Gomes, Joao L. P.; Fernandes, Larissa G.; Voltarelli, Vanessa A.; de Almeida, Ney R.; Jannig, Paulo R.; de Souza, Rodrigo W. Alves; Negrao, Carlos E.; Oliveira, Edilamar M.; Chammas, Roger; Alves, Christiano R. R.; Brum, Patricia C.

Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy 用于SMN2功能矫正的碱基编辑器的优化，以治疗脊髓性肌萎缩症

NATURE BIOMEDICAL ENGINEERING

IF26.6

2023-12-06

OAAI

Alves, Christiano R. R.; Ha, Leillani L.; Yaworski, Rebecca; Sutton, Emma R.; Lazzarotto, Cicera R.; Christie, Kathleen A.; Reilly, Aoife; Beauvais, Ariane; Doll, Roman M.; de la Cruz, Demitri; Maguire, Casey A.; Swoboda, Kathryn J.; Tsai, Shengdar Q.; Kothary, Rashmi; Kleinstiver, Benjamin P.

Exercise training modifies the whole blood DNA methylation profile in middle-aged and older women

JOURNAL OF APPLIED PHYSIOLOGY

IF3.3

2023-03-01

PREAI

Rodrigues, Guilherme da Silva; Noronha, Natalia Y.; Almeida, Mariana L.; Sobrinho, Andressa C. da S.; Watanabe, Ligia M.; Pinhel, Marcela A. de S.; de Lima, Joao G. R.; Zhang, Ren; Nonino, Carla B.; Alves, Christiano R. R.; Bueno Junior, Carlos R.

Muscle metabolic stress determines cancer cachexia severity in mice 肌肉代谢应激决定小鼠癌症恶病质的严重程度

FRONTIERS IN PHYSIOLOGY

IF3.4

2022-11-28

OAAI

Alves, Christiano; Goodyear, Laurie; Brum, Patricia

Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation

DIABETES

IF7.5

2022-03-15

OAAI

Kusuyama, Joji; Makarewicz, Nathan S.; Albertson, Brent G.; Alves-Wagner, Ana Barbara; Conlin, Royce H.; Prince, Noah B.; Alves, Christiano R. R.; Ramachandran, Krithika; Kozuka, Chisayo; Xiudong, Yang; Xia, Yang; Hirshman, Michael F.; Hatta, Toshihisa; Nagatomi, Ryoichi; Nozik, Eva S.; Goodyear, Laurie J.

Cancer-induced muscle atrophy is determined by intrinsic muscle oxidative capacity

FASEB JOURNAL

IF4.2

2021-06-12

PREAI

Alves, Christiano R. R.; Eichelberger, Eric J.; das Neves, Willian; Ribeiro, Marcio A. C.; Bechara, Luiz R. G.; Voltarelli, Vanessa A.; de Almeida, Ney R.; Hagen, Lars; Sharma, Animesh; Ferreira, Julio C. B.; Swoboda, Kathryn J.; Slupphaug, Geir; Brum, Patricia C.

Increased systemic HSP70B levels in spinal muscular atrophy infants

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2021-05-15

OAAI

Eichelberger, Eric J.; Alves, Christiano R. R.; Zhang, Ren; Petrillo, Marco; Cullen, Patrick; Farwell, Wildon; Hurt, Jessica A.; Staropoli, John F.; Swoboda, Kathryn J.

Serum Creatinine as a Potential Biomarker of Skeletal Muscle Atrophy in Non-small Cell Lung Cancer Patients 血清肌酐作为非小细胞肺癌患者骨骼肌萎缩的潜在生物标志物

FRONTIERS IN PHYSIOLOGY

IF3.4

2021-04-12

OAAI

das Neves, Willian; Alves, Christiano R. R.; de Souza Borges, Ana Paula; de Castro Jr, Gilberto

Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue

DIABETES

IF7.5

2021-02-09

OAAI

Nigro, Pasquale; Middelbeek, Roeland J. W.; Alves, Christiano R. R.; Rovira-Llopis, Susana; Ramachandran, Krithika; Rowland, Leslie A.; Moller, Andreas B.; Takahashi, Hirokazu; Alves-Wagner, Ana B.; Vamvini, Maria; Makarewicz, Nathan S.; Albertson, Brent G.; Hirshman, Michael F.; Goodyear, Laurie J.

Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

MOLECULAR METABOLISM

IF6.6

2020-09-01

OAAI

Alves, Christiano R. R.; das Neves, Willian; de Almeida, Ney R.; Eichelberger, Eric J.; Jannig, Paulo R.; Voltarelli, Vanessa A.; Tobias, Gabriel C.; Bechara, Luiz R. G.; Faria, Daniele de Paula; Alves, Maria J. N.; Hagen, Lars; Sharma, Animesh; Slupphaug, Geir; Moreira, Jose B. N.; Wisloff, Ulrik; Hirshman, Michael F.; Negrao, Carlos E.; de Castro, Gilberto, Jr.; Chammas, Roger; Swoboda, Kathryn J.; Ruas, Jorge L.; Goodyear, Laurie J.; Brum, Patricia C.

Whole-blood dysregulation of actin-cytoskeleton pathway in adult spinal muscular atrophy patients

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2020-06-17

OAAI

Siranosian, Jennifer J.; Nery, Flavia C.; Alves, Christiano R. R.; Siranosian, Benjamin A.; Lyons, Nicholas J.; Eichelberger, Eric J.; Garner, Reid; Da Silva Duarte Lepez, Salome; Johnstone, Alec J.; Subramanian, Aravind; Swoboda, Kathryn J.

Serum creatinine is a biomarker of progressive denervation in spinal muscular atrophy

NEUROLOGY

IF8.5

2020-03-03

OAAI

Alves, Christiano R. R.; Zhang, Ren; Johnstone, Alec J.; Garner, Reid; Nwe, Pann H.; Siranosian, Jennifer J.; Swoboda, Kathryn J.

Impaired kidney structure and function in spinal muscular atrophy

NEUROLOGY-GENETICS

IF3.7

2019-10-01

OAAI

Nery, Flavia C.; Siranosian, Jennifer J.; Rosales, Ivy; Deguise, Marc-Olivier; Sharma, Amita; Muhtaseb, Abdurrahman W.; Nwe, Pann; Johnstone, Alec J.; Zhang, Ren; Fatouraei, Maryam; Huemer, Natassja; Alves, Christiano R. R.; Kothary, Rashmi; Swoboda, Kathryn J.

Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2019-09-01

OAAI

Alves, Christiano R. R.; MacDonald, Tara L.; Nigro, Pasquale; Pathak, Prerana; Hirshman, Michael F.; Goodyear, Laurie J.; Lessard, Sarah J.

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism

NATURE METABOLISM

IF20.8

2019-02-11

151

OAAI

Takahashi, Hirokazu; Alves, Christiano R. R.; Stanford, Kristin I.; Middelbeek, Roeland J. W.; Nigro, Pasquale; Ryan, Rebecca E.; Xue, Ruidan; Sakaguchi, Masaji; Lynes, Matthew D.; So, Kawai; Mul, Joram D.; Lee, Min-Young; Balan, Estelle; Pan, Hui; Dreyfuss, Jonathan M.; Hirshman, Michael F.; Azhar, Mohamad; Hannukainen, Jarna C.; Nuutila, Pirjo; Kalliokoski, Kari K.; Nielsen, Soren; Pedersen, Bente K.; Kahn, C. Ronald; Tseng, Yu-Hua; Goodyear, Laurie J.

Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity

SCIENTIFIC REPORTS

IF3.9

2018-12-11

OAAI

Souza, Rodrigo W. A.; Alves, Christiano R. R.; Medeiros, Alessandra; Rolim, Natale; Silva, Gustavo J. J.; Moreira, Jose B. N.; Alves, Marcia N.; Wohlwend, Martin; Gebriel, Mohammed; Hagen, Lars; Sharma, Animesh; Koch, Lauren G.; Britton, Steven L.; Slupphaug, Geir; Wisloff, Ulrik; Brum, Patricia C.

研究方向