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J

James Douglas Engel

university of michigan

78H指数
291论文数
2.3W被引数
收录论文 83
发表时间
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Murine model for Congenital Dyserythropoietic Anemia Type I先天性红细胞生成障碍性贫血I型的鼠模型
errBlood Advances
IF7.1
err2026-09-10
err0
errOAAI
errAnn Friedman; Richard King; Greggory Myers; Lei Yu; Ingrid L. Bergin; Zesen Lin; Claire Drysdale; Carea Mullin; Edgar D. Cruz; Ginette Balbin-Cuesta; Xiaofang Liu; Patrick J. Gallagher; Guojing Zhu; Beth McGee; Annemarie Lang; Sharon A. Singh; James Douglas Engel; Patrick G. Gallagher; Rami Khoriaty
err分享
err收藏
LSD1 inhibition ameliorates congenital dyserythropoietic anemia type IILSD1抑制改善了先天性 dyserythropoietic anemia type II
errScience Translational Medicine
IF14.6
err2026-03-25
err0
PREAI
errLei Yu; Yu Wang; Richard King; Greggory Myers; Kaiwen Deng; Beth McGee; Ann Friedman; Ginette Balbin-Cuesta; Zesen Lin; Claire Drysdale; Xiaofang Liu; Joseph C. Min; Claire Kerpet; Yuanfang Guan; Patrick J. Gallagher; Ayse Bilge Ozel; Aaron Robida; James Douglas Engel; Rami Khoriaty
err分享
err收藏
Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model新型、高效且口服生物利用的LSD1抑制剂在镰状细胞病小鼠模型中诱导胎儿血红蛋白合成
errBlood
IF23.1
err2025-05-09
err0
PREAI
errYu Wang; Lei Yu; Kaiwen Deng; Mathivanan Packiarajan; Angelo Aguilar; Sojin An; Xiaofang Liu; Greggory Myers; Hoon Oh; Sharon A. Singh; Uhn-soo Cho; Shaomeng Wang; Yuanfang Guan; Andrew D. White; Rami Khoriaty; James Douglas Engel
err分享
err收藏
A genome-wide screen identifies genes required for erythroid differentiation全基因组筛选鉴定出参与红系分化的基因
errNATURE COMMUNICATIONS
IF15.7
err2025-04-12
err0
errOAAI
errMyers, Greggory; Friedman, Ann; Yu, Lei; Pourmandi, Narges; Kerpet, Claire; Ito, Masaki A.; Saba, Rilie; Tang, Vi; Ozel, Ayse Bilge; Bergin, Ingrid L.; Johnson, Craig N.; Ku, Chia-Jui; Wang, Yu; Balbin-Cuesta, Ginette; Lim, Kim-Chew; Lin, Zesen; Drysdale, Claire; Mcgee, Beth; Kurita, Ryo; Nakamura, Yukio; Liu, Xiaofang; Siemieniak, David; Singh, Sharon A.; Lyssiotis, Costas A.; Maillard, Ivan; Weisman, Lois S.; Engel, James Douglas; Khoriaty, Rami
err分享
err收藏
The abundance of the short GATA1 isoform affects megakaryocyte differentiation and leukemic predisposition in mice
errhematology oncology
IF13.5
err2024-02-26
err0
errOAAI
errIshihara, Daishi; Hasegawa, Atsushi; Hirano, Ikuo; Engel, James Douglas; Yamamoto, Masayuki; Shimizu, Ritsuko
err分享
err收藏
Strain-dependent modifiers exacerbate familial leukemia caused by GATA1-deficiency
errhematology oncology
IF13.5
err2024-02-26
err0
errOAAI
errHirano, Ikuo; Abe, Kanako; Engel, James Douglas; Yamamoto, Masayuki; Shimizu, Ritsuko
err分享
err收藏
Murine erythroid differentiation kinetics in vivo under normal and anemic stress conditions
errBLOOD ADVANCES
IF7.1
err2023-09-27
err1
errOAAI
errMyers, Greggory; Wang, Yu; Wang, Qing; Friedman, Ann; Sanchez-Martinez, Alejandra; Liu, Xiaofang; Sharon, Singh A.; Lim, Kim-Chew; Khoriaty, Rami; Engel, James Douglas; Yu, Lei
err分享
err收藏
Linear distance from the locus control region determines ε-globin transcriptional activity与基因座控制区的线性距离决定了 ε-珠蛋白的转录活性
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-04-01
err11
errOAAI
errShimotsuma, Motoshi; Matsuzaki, Hitomi; Tanabe, Osamu; Campbell, Andrew D.; Engel, James Douglas; Fukamizu, Akiyoshi; Tanimoto, Keiji
err分享
err收藏
Reconstitution of human β-globin locus control region hypersensitive sites in the absence of chromatin assembly
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err50
errOAAI
errLeach, KM; Nightingale, K; Igarashi, K; Levings, PP; Engel, JD; Becker, PB; Bungert, J
err分享
err收藏
Human β-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err60
errOAAI
errTanimoto, K; Sugiura, A; Omori, A; Felsenfeld, G; Engel, JD; Fukamizu, A
err分享
err收藏
Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes遗传证据表明小Maf蛋白对于抗氧化反应元件依赖性基因的激活至关重要
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err270
errOAAI
errKatsuoka, F; Motohashi, H; Ishii, T; Aburatani, H; Engel, JD; Yamamoto, M
err分享
err收藏
GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err82
errOAAI
errKobayashi-Osaki, M; Ohneda, O; Suzuki, N; Minegishi, N; Yokomizo, T; Takahashi, S; Lim, KC; Engel, JD; Yamamoto, M
err分享
err收藏
Identification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err17
errOAAI
errShimizu, T; Oishi, T; Omori, A; Sugiura, A; Hirota, K; Aoyama, H; Saito, T; Sugaya, T; Kon, Y; Engel, JD; Fukamizu, A; Tanimoto, K
err分享
err收藏
MafG sumoylation is required for active transcriptional repression
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err52
errOAAI
errMotohashi, Hozumi; Katsuoka, Fumiki; Miyoshi, Chika; Uchimura, Yasuhiro; Saitoh, Hisato; Francastel, Claire; Engel, James Douglas; Yamamoto, Masayuki
err分享
err收藏
Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err57
errOAAI
errKhandekar, M; Suzuki, N; Lewton, J; Yamamoto, M; Engel, JD
err分享
err收藏
MafB is essential for renal development and F4/80 expression in macrophages
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err193
errOAAI
errMoriguchi, Takashi; Hamada, Michito; Morito, Naoki; Terunuma, Tsumoru; Hasegawa, Kazuteru; Zhang, Chuan; Yokomizo, Tomomasa; Esaki, Ritsuko; Kuroda, Etsushi; Yoh, Keigyou; Kudo, Takashi; Nagata, Michio; Greaves, David R.; Engel, James Douglas; Yamamoto, Masayuki; Takahashi, Satoru
err分享
err收藏
Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err48
errOAAI
errKatsuoka, F; Motohashi, H; Tamagawa, Y; Kure, S; Igarashi, K; Engel, JD; Yamamoto, M
err分享
err收藏
MafA is a key regulator of glucose-stimulated insulin secretion
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err514
errOAAI
errZhang, C; Moriguchi, T; Kajihara, M; Esaki, R; Harada, A; Shimohata, H; Oishi, H; Hamada, M; Morito, N; Hasegawa, K; Kudo, T; Engel, JD; Yamamoto, M; Takahashi, S
err分享
err收藏
Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err39
errOAAI
errSuzuki, Mikiko; Yamazaki, Hiromi; Mukai, Harumi Y.; Motohashi, Hozumi; Shi, Lihong; Tanabe, Osamu; Engel, James Douglas; Yamamoto, Masayuki
err分享
err收藏
UG4 Enhancer-Driven GATA-2 and Bone Morphogenetic Protein 4 Complementation Remedies the CAKUT Phenotype in Gata2 Hypomorphic Mutant Mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err22
errOAAI
errAinoya, Keiko; Moriguchi, Takashi; Ohmori, Shin'ya; Souma, Tomokazu; Takai, Jun; Morita, Masanobu; Chandler, Kelly J.; Mortlock, Douglas P.; Shimizu, Ritsuko; Engel, James Douglas; Lim, Kim-Chew; Yamamoto, Masayuki
err分享
err收藏

研究方向

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合作学者
合作期刊
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Masayuki Yamamoto
H 指数: 193 · 论文数: 2.1K
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F
Frank Grosveld
H 指数: 121 · 论文数: 528
F
Frédéric J. de Sauvage
H 指数: 103 · 论文数: 301
Shaomeng Wang 封面图
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