Michael Lardelli

Adelaide University

H指数:41

被引数:5,972

个人简介

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教育背景

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工作经历

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荣誉奖项

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Ketone-Dependent Restoration of Autophagy and Mitochondrial Quality Control Through VPS35 in a Drosophila Model of C99-Induced Neurodegeneration

通过VPS35介导的酮依赖性自噬和线粒体质量控制恢复，在C99诱导神经退行性的果蝇模型中

Cells

IF5.2

2026-06-150

DNAJC6 Parkinson’s disease: Endolysosomal dysfunction and emerging roles for oligodendrocytes

DNAJC6帕金森病：溶酶体功能障碍和少突胶质细胞的 emerging roles

npj Parkinson's Disease

IF8.2

2026-04-040

OAAI

Housing and husbandry factors affecting zebrafish novel tank test responses: a global multi-laboratory study

影响斑马鱼新水箱测试反应的饲养和繁育因素：一项全球多实验室研究

LAB ANIMAL

IF3.9

2025-05-260

Hillman, Courtney; Fontana, Barbara D.; Amstislavskaya, Tamara G.; Gorbunova, Maria A.; Altenhofen, Stefani; Barthelson, Karissa; Bastos, Leonardo M.; Borba, Joao V.; Bonan, Carla D.; Brennan, Caroline H.; Farias-Cea, Amaury; Cooper, Austin; Corcoran, Jamie; Dondossola, Eduardo R.; Martinez-Duran, Luis M.; Gallas-Lopes, Matheus; Galstyan, David S.; Garcia, Ella O.; Gerken, Ewan; Hindges, Robert; Kenney, Justin W.; Kleshchev, Maxim A.; Kolesnikova, Tatiana O.; Leggieri, Adele; Khatsko, Sergey L.; Lardelli, Michael; Lodetti, Guilherme; Lombardelli, Giulia; Luchiari, Ana C.; Portela, Stefani M.; Medan, Violeta; Moutinho, Lirane M.; Nekhoroshev, Evgeny V.; Petersen, Barbara D.; Petrunich-Rutherford, Maureen L.; Piato, Angelo; Porfiri, Maurizio; Read, Emily; Resmim, Cassio M.; Rico, Eduardo P.; Rosemberg, Denis B.; de Abreu, Murilo S.; Salazar, Catia A.; Stahlhofer-Buss, Thailana; Teixeira, Julia R.; Valentim, Ana M.; Zhdanov, Alexander V.; Iturriaga-Vasquez, Patricio; Wang, Xian; Wong, Ryan Y.; Parker, Matthew O.

Multi-omics analyses of early-onset familial Alzheimer's disease and Sanfilippo syndrome zebrafish models reveal commonalities in disease mechanisms

多组学分析揭示了早期发病的家族性阿尔茨海默病和Sanfilippo综合征斑马鱼模型在疾病机制上的共同点。

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

IF4.2

2025-03-010

PRE

Brain Transcriptome Analysis of a Protein-Truncating Mutation in Sortilin-Related Receptor 1 Associated With Early-Onset Familial Alzheimer's Disease Indicates Early Effects on Mitochondrial and Ribosome Function

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-02-0510

OAAI

The Use of Zebrafish in Transcriptome Analysis of the Early Effects of Mutations Causing Early Onset Familial Alzheimer's Disease and Other Inherited Neurodegenerative Conditions

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-05-074

PRE

Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis

plos biology

IF3.6

2024-02-121

OAAI

An Alternative View of Familial Alzheimer's Disease Genetics

家族性阿尔茨海默病遗传学的另一种观点

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2023-09-129

Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism

DISEASE MODELS & MECHANISMS

IF3.3

2022-01-267

OAAI

PRESENILIN 1 Mutations Causing Early-Onset Familial Alzheimer's Disease or Familial Acne Inversa Differ in Their Effects on Genes Facilitating Energy Metabolism and Signal Transduction

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2021-06-2910

OAAI

Loss of park7 activity has differential effects on expression of iron responsive element (IRE) gene sets in the brain transcriptome in a zebrafish model of Parkinson's disease

MOLECULAR BRAIN

IF2.9

2021-05-249

OAAI

Relevance of a Truncated PRESENILIN 2 Transcript to Alzheimer's Disease and Neurodegeneration

截短的早老素2转录本与阿尔茨海默氏病和神经变性的相关性

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2021-04-204

PREAI

Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer's disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis

BMC GENOMICS

IF3.7

2021-03-2416

OAAI

No observed effect on brain vasculature of Alzheimer's disease-related mutations in the zebrafish presenilin 1 gene

MOLECULAR BRAIN

IF2.9

2021-01-251

OAAI

Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in theSORL1gene implicated in early onset familial Alzheimer's disease

MOLECULAR BRAIN

IF2.9

2020-10-1926

OAAI

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of presenilin 1

HUMAN MOLECULAR GENETICS

IF3.2

2020-06-2612

OAAI

Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production

MOLECULAR BRAIN

IF2.9

2019-05-0323

OAAI

Alternative splicing in a presenilin 2 variant associated with Alzheimer disease

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

IF3.9

2019-03-1032

OAAI

Braggin, Jacquelyn E.; Bucks, Stephanie A.; Course, Meredith M.; Smith, Carole L.; Sopher, Bryce; Osnis, Leah; Shuey, Kiel D.; Domoto-Reilly, Kimiko; Caso, Christina; Kinoshita, Chizuru; Scherpelz, Kathryn P.; Cross, Chloe; Grabowski, Thomas; Nik, Seyyed H. M.; Newman, Morgan; Garden, Gwenn A.; Leverenz, James B.; Tsuang, Debby; Latimer, Caitlin; Gonzalez-Cuyar, Luis F.; Keene, Christopher Dirk; Morrison, Richard S.; Rhoads, Kristoffer; Wijsman, Ellen M.; Dorschner, Michael O.; Lardelli, Michael; Young, Jessica E.; Valdmanis, Paul N.; Bird, Thomas D.; Jayadev, Suman

A Review of the Familial Alzheimer's Disease Locus PRESENILIN 2 and Its Relationship to PRESENILIN 1

家族性阿尔茨海默病位点早老素2及其与早老素1关系的综述

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2018-12-1220

PREAI

Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer's Disease

FRONTIERS IN NEUROSCIENCE

IF3.2

2018-08-1337

OAAI

Michael Lardelli

个人简介

教育背景

工作经历

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