未登录 Multi-omic integration reveals intra-tumour heterogeneity and identifies disulfiram and copper as a synergistic therapy in paediatric ependymoma 多组学整合揭示肿瘤内异质性，并鉴定出二硫仑和铜作为儿科室管膜瘤的协同疗法 Pandele, Alina; Whitby, Alison; Lankford, Sophie; Martinez-Jarquin, Sandra; Bastiancich, Chiara; Macarthur, Donald; Kamaly-Asl, Ian; Barrett, David; Grundy, Richard; Hyun-Kim, Dong; Rahman, Ruman 分享 收藏
Neurosurgical application of olaparib from a thermo-responsive paste potentiates DNA damage to prolong survival in malignant glioma Serra, Riccardo; Smith, Stuart J.; Rowlinson, Jonathan; Gorelick, Noah; Moloney, Cara; McCrorie, Phoebe; Veal, Gareth J.; Berry, Philip; Chalmers, Anthony J.; Suk, Ian; Shakesheff, Kevin M.; Alexander, Cameron; Grundy, Richard G.; Brem, Henry; Tyler, Betty M.; Rahman, Ruman 分享 收藏
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INTRAOPERATIVE APPLICATION OF A POLYMER-BASED HYDROGEL AGAINST MEDULLOBLASTOMA GROUP 3 AND ATYPICAL TERATOID/RHABDOID TUMOURS Moloney, Cara; ElSherbeny, Amr; McCrorie, Phoebe; Porter, Harry; Bastiancich, Chiara; Bayraktutan, Hulya; Oz, Umut Can; Grundy, Richard G.; Nilsson, Karin Forsberg; Brem, Henry; Alexander, Cameron; Tyler, Betty; Smith, Stuart J.; Rahman, Ruman 分享 收藏
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THE MANAGEMENT OF PEDIATRIC AND ADOLESCENT SPINAL EPENDYMOMA; A 20-YEAR NATIONAL EVALUATION INVOLVING UNITED KINGDOM PEDIATRIC ONCOLOGY PRIMARY TREATMENT CENTERS ON BEHALF OF THE UK CHILDREN'S CANCER AND LEUKAEMIA GROUP (CCLG) Deghedy, Marwa; English, Martin; Curry, Helen; Nicholson, James; OHare, Patricia; McCarthy, Anthony; Uzunova, Lena; Curry, Sarah; Wilson, Shaun; Jorgensen, Mette; Thompson, Dominic; Cox, Rachel; Ronghe, Milind; Brougham, Mark; McAndrew, Rachel; Lee, Victoria; Bailey, Simon; Thorbinson, Colin; Goodden, John; Picton, Susan; Dias, Sandra; Saeed, Fozia; Srivatsa, Kavitha; Ritzmann, Timothy; Grundy, Richard; Kilday, John-Paul 分享 收藏
Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups 髓母细胞瘤的代谢物谱，用于分子疾病组的快速和无创检测 Kohe, Sarah; Bennett, Christopher; Burte, Florence; Adiamah, Magretta; Rose, Heather; Worthington, Lara; Scerif, Fatma; MacPherson, Lesley; Gill, Simrandip; Hicks, Debbie; Schwalbe, Edward C.; Crosier, Stephen; Storer, Lisa; Lourdusamy, Ambarasu; Mitra, Dipyan; Morgan, Paul S.; Dineen, Robert A.; Avula, Shivaram; Pizer, Barry; Wilson, Martin; Davies, Nigel; Tennant, Daniel; Bailey, Simon; Williamson, Daniel; Arvanitis, Theodoros N.; Grundy, Richard G.; Clifford, Steven C.; Peet, Andrew C. 分享 收藏
OPTIMISING BIOMARKERS FOR ACCURATE EPENDYMOMA DIAGNOSIS, PROGNOSTICATION AND STRATIFICATION WITHIN INTERNATIONAL CLINICAL TRIALS: A BIOMECA STUDY Chapman, Rebecca J.; Ghasemi, David R.; Andreiuolo, Felipe; Zschernack, Valentina; Espariat, Arnault Tauziede; Buttarelli, Francesca; Giangaspero, Felice; Grill, Jacques; Haberler, Christine; Paine, Simon M. L.; Scott, Ian; Jacques, Thomas S.; Sill, Martin; Stephan, Pfister; Kilday, John Paul; LeBlond, Pierre; Massimino, Maura; Modena, Piergiorgio; Varlet, Pascale; Pietsch, Torsten; Grundy, Richard G.; Pajtler, Kristian W.; Ritzmann, Timothy A. 分享 收藏
A MULTICENTER STUDY OF POOR PROGNOSIS CHROMOSOME 1Q GAIN AND/OR 6Q LOSS IN POSTERIOR FOSSA A EPENDYMOMA SHOWS INCREASED PREVALENCE FROM 20% AT DIAGNOSIS TO 60% AT FIRST RECURRENCE Donson, Andrew; Bertrand, Kelsey; Riemondy, Kent; Gao, Dexiang; Sanford, Bridget; Norris, Gregory; Fu, Rui; Willard, Nicholas; Griesinger, Andrea; Amani, Vladimir; Grimaldo, Enrique; Hankinson, Todd; Booker, Ffyona; Grundy, Richard; Pajtler, Kristian; Ellison, David; Ritzmann, Timothy 分享 收藏
Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study 后颅窝A组室管膜瘤复发时高危染色体1q增加和6q丢失显著增加: 一项多中心研究 Donson, Andrew M.; Bertrand, Kelsey C.; Riemondy, Kent A.; Gao, Dexiang; Zhuang, Yonghua; Sanford, Bridget; Norris, Gregory A.; Chapman, Rebecca J.; Fu, Rui; Willard, Nicholas; Griesinger, Andrea M.; de Sousa, Graziella Ribeiro; Amani, Vladimir; Grimaldo, Enrique; Hankinson, Todd C.; Booker, Ffyona; Sill, Martin; Grundy, Richard G.; Pajtler, Kristian W.; Ellison, David W.; Foreman, Nicholas K.; Ritzmann, Timothy A. 分享 收藏
Lineage switching of the cellular distribution of BRAFV600E in multisystem Langerhans cell histiocytosis Milne, Paul; Bomken, Simon; Slater, Olga; Kumar, Ashish; Nelson, Adam; Roy, Somak; Velazquez, Jessica; Mankad, Kshitij; Nicholson, James; Yeomanson, Dan; Grundy, Richard; Kamal, Ahmed; Penn, Anthony; Pears, Jane; Millen, Gerard; Morland, Bruce; Hayden, James; Lam, Jason; Madkhali, Maymoon; MacDonald, Jamie; Singh, Preeti; Pagan, Sarah; Rodriguez-Galindo, Carlos; Minkov, Milen; Donadieu, Jean; Picarsic, Jennifer; Allen, Carl; Bigley, Venetia; Collin, Matthew 分享 收藏
Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature 具有CIC基因融合的儿科型高级别神经上皮肿瘤具有共同的DNA甲基化特征 Sievers, Philipp; Sill, Martin; Schrimpf, Daniel; Abdullaev, Zied; Donson, Andrew M. M.; Lake, Jessica A. A.; Friedel, Dennis; Scheie, David; Tynninen, Olli; Rauramaa, Tuomas; Vepsalainen, Kaisa L.; Samuel, David; Chapman, Rebecca; Grundy, Richard G. G.; Pajtler, Kristian W. W.; Tauziede-Espariat, Arnault; Metais, Alice; Varlet, Pascale; Snuderl, Matija; Jacques, Thomas S. S.; Aldape, Kenneth; Reuss, David E. E.; Korshunov, Andrey; Wick, Wolfgang; Pfister, Stefan M. M.; von Deimling, Andreas; Sahm, Felix; Jones, David T. W. 分享 收藏
Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study Chapman, Rebecca J.; Ghasemi, David R.; Andreiuolo, Felipe; Zschernack, Valentina; Tauziede Espariat, Arnault; Buttarelli, Francesca R.; Giangaspero, Felice; Grill, Jacques; Haberler, Christine; Paine, Simon M. L.; Scott, Ian; Jacques, Thomas S.; Sill, Martin; Pfister, Stefan; Kilday, John-Paul; Leblond, Pierre; Massimino, Maura; Witt, Hendrik; Modena, Piergiorgio; Varlet, Pascale; Pietsch, Torsten; Grundy, Richard G.; Pajtler, Kristian W.; Ritzmann, Timothy A. 分享 收藏
Recurrent posterior fossa group A (PFA) ependymoma in a young child with constitutional mismatch repair deficiency (CMMRD) 患有宪法错配修复缺陷 (CMMRD) 的幼儿复发性后颅窝A组 (PFA) 室管膜瘤 Briggs, Mayen; Das, Anirban; Firth, Helen; Levine, Adrian; Sanchez-Ramirez, Santiago; Negm, Logine; Ercan, Ayse B.; Chung, Jill; Bianchi, Vanessa; Jalloh, Ibrahim; Phyu, Poe; Thorp, Nicky; Grundy, Richard G.; Hawkins, Cynthia; Trotman, Jamie; Tarpey, Patrick; Tabori, Uri; Allinson, Kieren; Murray, Matthew J. 分享 收藏
Recurrent ACVR1 mutations in posterior fossa ependymoma 后颅窝室管膜瘤的复发性ACVR1突变 Pratt, Drew; Lucas, Calixto-Hope G.; Selvam, Pavalan Panneer; Abdullaev, Zied; Ketchum, Courtney; Quezado, Martha; Armstrong, Terri S.; Gilbert, Mark R.; Papanicolau-Sengos, Antonios; Raffeld, Mark; Choo-Wosoba, Hyoyoung; Chan, Priya; Whipple, Nicholas; Nasrallah, MacLean; Santi, Mariarita; Ramaswamy, Vijay; Giannini, Caterina; Ritzmann, Timothy A.; Grundy, Richard G.; Burford, Anna; Jones, Chris; Hawkins, Cynthia; Venneti, Sriram; Solomon, David A.; Aldape, Kenneth 分享 收藏
Phase II study of intravenous etoposide in patients with relapsed ependymoma (CNS 2001 04) 复发性室管膜瘤患者静脉内依托泊苷的II期研究 (CNS 2001 04) Apps, John R.; Maycock, Shanna; Ellison, David W.; Jaspan, Timothy; Ritzmann, Timothy A.; Macarthur, Donald; Mallucci, Conor; Wheatley, Keith; Veal, Gareth J.; Grundy, Richard G.; Picton, Susan 分享 收藏
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