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K

Kaj Blennow

the sahlgrenska academy at the university of gothenburg
H指数:214
被引数:23.2万
浏览量:0

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Alzheimer’s disease genetics converges on microglial and neuronal dysregulation

阿尔茨海默病遗传学研究聚焦于小胶质细胞和神经元功能失调

Nature
IF48.5
2026-10-280
OAAI
Emil Uffelmann; Douglas P. Wightman; Shahram Bahrami; Alexey A. Shadrin; Vera Fominykh; Takafumi Ojima; Chenyang Jiang; Christian Benner; Elisa Moreno; Adrian I. Campos; Jesper Q. Thomassen; Emmanuel Minois-Genin; Hei Man Wu; G. Bragi Walters; Richard Sherva; Tian Lin; Xuemin Wang; Julien Bryois; Kristi Krebs; Marijn Schipper; Akira Narita; Alessandro Serretti; Anja H. Simonsen; Anna L. van Seumeren; Anne Corbett; Anne-Brita Knapskog; Annette M. Hartmann; Anouk den Braber; Argonde C. van Harten; Arvid Harder; Arvid Rongve; Bengt O. Madsen; Betty M. Tijms; Bitten Aagaard; Bjørn Lichtwarck; Bjørn-Eivind Kirsebom; Byron Creese; Chandra A. Reynolds; Sara Hägg; Ida K. Karlsson; Christian Erikstrup; Christina Mikkelsen; Clive Ballard; Dag Aarsland; Daichi Shigemizu; Dan Rujescu; Daniel Gudbjartsson; Eivind Aakhus; Erik Sørensen; Eystein Stordal; Flora H. Duits; Frank J. Wolters; Frederic Blanc; Geert Jan Biessels; Geir Selbæk; Geir Bråthen; Gen Tamiya; Gunhild Waldemar; Harro Seelaar; Helga Eyjolfsdottir; Henne Holstege; Henning Bundgaard; Henrik Zetterberg; Henrik Ullum; Ina Giegling; Ingmar Skoog; Ingrid T. Medbøen; Ingvild Saltvedt; Irena Rektorova; J. Michael Gaziano; Jan Haavik; Jens Hjerling-Leffler; Jiao Luo; Jon Snaedal; Everard G. B. Vijverberg; Julia M. Sealock; Kaj Blennow; Kaja Nordengen; Karin Persson; Katja Scheffler; Koichi Matsuda; Kouichi Ozaki; Lasse Pihlstrøm; Lavinia Athanasiu; Lene Pålhaugen; Marc Hulsman; Margda Waern; Maria Averina; Marianne Wettergreen; Marta R. Moksnes; Martijn Huisman; Masayuki Yamamoto; Mathias Toft; Matthew S. Panizzon; Mie Topholm Bruun; Mohsen Ghanbari; Monique Franc; Nancy L. Pedersen; Nathaniel Y. Bell; Niccoló Tesi; Ole B. Pedersen; Oleksandr Frei; Olivier Bousiges; Per Svenningsson; Pieter J. Visser; Qingqin S. Li; Richard Hauger; Rui Zhang; Shinichi Namba; Sigrid B. Sando; Silke Kern; Srdjan Djurovic; Steinunn Thordardottir; Tanya N. Phung; Thomas Truelsen; Thomas Werge; Thomas F. Hansen; Tomoki Kyosaka; Torgeir Engstad; Tormod Fladby; Victoria Merritt; Sverre Bergh; Wiesje M. van der Flier; Rujin Wang; Eli A. Stahl; Basavaraj Hooli; Lea K. Davis; Mark W. Logue; Kelli Lehto; Anna Zettergren; Ben M. Brumpton; Jian Zeng; Peter M. Visscher; Paul F. O’Reilly; Anubha Mahajan; Manuel Ferreira; Yukinori Okada; Sven J. van der Lee; Sisse R. Ostrowski; Ruth Frikke-Schmidt; Hreinn Stefansson; Karl Heilbron; Ole A. Andreassen; Danielle Posthuma
Locus coeruleus activity is related to sleep and 24-h rest-activity rhythms in the context of plasma Alzheimer’s disease markers: a 7T MRI study of older individuals

蓝斑活动与血浆阿尔茨海默病标志物背景下的睡眠和24小时休息-活动节律相关：一项针对老年人的7T MRI研究

Alzheimers Research & Therapy
IF7.6
2026-10-010
OA
Yuliya Patsyuk; Prokopis Prokopiou; Nicholas J. Ashton; Shorena Janelidze; Kaj Blennow; Oskar Hansson; Henrik Zetterberg; Benedikt A. Poser; Heidi I.L. Jacobs; Maxime Van Egroo
A centiloid-scaled crossover of amyloid and tau influences on plasma p-Tau217 along the Alzheimer’s disease continuum

阿尔茨海默病连续谱中，以百分之一洛德为单位计的淀粉样蛋白和tau蛋白影响对血浆p-Tau217的交叉影响

Alzheimers Research & Therapy
IF7.6
2026-09-290
OAAI
Hyunwoo Lee; Yuna Gu; Heekyoung Kang; Daeun Shin; Sohyun Yim; Seonghyeon Kim; Hee Kyung Park; Hee Jin Kim; Duk L. Na; Henrik Zetterberg; Kaj Blennow; Fernando Gonzalez-Ortiz; Nicholas J Ashton; Joseph Therriault; Nesrine Rahmouni; Pedro Rosa-Neto; Michael W. Weiner; Sang Won Seo; Jun Pyo Kim
Circulating Metabolite Signatures Associated With Amyloid Positivity, Cognitive Performance and Plasma P-tau181 Levels in Cognitively Unimpaired Older Adults

与淀粉样蛋白阳性、认知表现和血浆P-tau181水平相关的循环代谢物特征在认知功能完好老年人中的研究

Molecular Neurobiology
IF4.3
2026-09-140
OAAI
Tahmida Sharmin; James D. Doecke; Pratishtha Chatterjee; Hamid R. Sohrabi; Henrik Zetterberg; Nicholas J. Ashton; Manohar L. Garg; Kaj Blennow; Ralph N. Martins
CSF p-tau205: a biomarker of Alzheimer’s disease progression and biological staging

脑脊液p-tau205：阿尔茨海默病进展和生物学分期的生物标志物

Molecular Psychiatry
IF10.1
2026-08-270
OA
Juan Lantero-Rodriguez; Shorena Janelidze; Sebastian Palmqvist; Luisa Sophie Braun-Wohlfahrt; Jakub Vavra; Divya Bali; Anna Orduña Dolado; Niklas Mattsson-Carlgren; Erik Stomrud; Henrik Zetterberg; Kaj Blennow; Oskar Hansson; Laia Montoliu-Gaya; Gemma Salvadó
Cerebrospinal fluid biomarkers reveal transdiagnostic synaptic dysfunction across major psychiatric disorders

脑脊液生物标志物揭示主要精神疾病跨诊断的突触功能障碍

Nature Communications
IF15.7
2026-07-300
OA
Andreas Göteson; Johanna Nilsson; Elena Camporesi; Anna Luisa Klahn; Elin Hörbeck; Robert Sigström; Lina Jonsson; Timea Sparding; Erik Pålsson; Aurimantas Pelanis; Anneli Goulding; Anniella Isgren; Sophie Erhardt; Simon Cervenka; Cynthia M. Bulik; Henrik Zetterberg; Kaj Blennow; Carl M. Sellgren; Ann Brinkmalm; Mikael Landén
Spatiotemporal dynamics of tau extent and load increase in Alzheimer’s disease across four longitudinal cohorts

阿尔茨海默病中tau蛋白范围和负荷增加的时空动态变化：基于四项纵向队列研究

Nature Aging
IF19.4
2026-07-140
OAAI
Arthur C. Macedo; Lydia Trudel; Joseph Therriault; Nesrine Rahmouni; Étienne Aumont; Gleb Bezgin; Seyyed Ali Hosseini; Cécile Tissot; Tevy Chan; Stijn Servaes; Brandon Hall; Yi-Ting Wang; Kely Quispialaya-Socualaya; Marcel S. Woo; Jaime Fernandez-Arias; Jenna Stevenson; Yansheng Zheng; Marina Pereira Gonçalves; Firoza Z. Lussier; João Pedro Ferrari-Souza; Pamela C. L. Ferreira; Bruna Bellaver; Guilherme Povala; Livia Silva do Amaral; Gassan Massarweh; Jean-Paul Soucy; Karin L. Meeker; Meredith N. Braskie; Tobey J. Betthauser; Bradley T. Christian; Ramiro Eduardo Rea Reyes; Jessica K. Caldwell; Nicholas J. Ashton; Thomas K. Karikari; Henrik Zetterberg; Kaj Blennow; Eduardo R. Zimmer; Andréa L. Benedet; Sterling C. Johnson; Tharick A. Pascoal; Pedro Rosa-Neto
Gut bacterial metabolite imidazole propionate potentiates Alzheimer’s disease pathology

肠道细菌代谢物咪唑丙酸盐加剧阿尔茨海默病病理

Nature Communications
IF15.7
2026-06-260
OAAI
Vaibhav Vemuganti; Jea Woo Kang; Qijun Zhang; Eric R. McGregor; James R. Hilser; Ruben Aquino-Martinez; Sandra Harding; Joseph Lawrence Harpt; Katharina R. Beck; Hailey Bussan; Jessamine F. Kuehn; Yuetiva Deming; Rachel Studer; Sterling C. Johnson; Sanjay Asthana; Henrik Zetterberg; Kaj Blennow; Corinne D. Engelman; Hooman Allayee; Rozalyn M. Anderson; Tyler K. Ulland; Fredrik Bäckhed; Barbara B. Bendlin; Federico E. Rey
Circulating Sphingomyelins Correlate With Plasma T-Tau in Cognitively Unimpaired Older Adults at Risk of Developing Alzheimer's Disease

循环鞘磷脂与认知未受损且具有阿尔茨海默病风险的老年人群的血浆总tau蛋白相关

Journal of Neurochemistry
IF4
2026-05-080
OA
Tahmida Sharmin; James D. Doecke; Pratishtha Chatterjee; Steve Pedrini; Hamid R. Sohrabi; Nicholas J. Ashton; Henrik Zetterberg; Manohar L. Garg; Kaj Blennow; Ralph N. Martins
GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy

脑脊液阿尔茨海默病生物标志物的GWAS荟萃分析揭示了调控脂质、脑容量和自噬的基因位点

Nature Communications
IF15.7
2026-04-210
OAAI
Jigyasha Timsina; Chenyang Jiang; Daniel L. McCartney; Feifei Tao; Maria Carolina Dalmasso; Jenna Najar; Federica Anastasi; Olena Ohlei; Raquel Puerta Fuentes; Chenyu Yang; Joseph Bradley; Daniel Western; Muhammad Ali; Ciyang Wang; Chengran Yang; Ying Wu; Menghan Liu; John Budde; Julie Williams; Rebecca Mahoney; Atahualpa Castillo Morales; Timothy J. Hohman; Logan Dumitrescu; Ting-Chen Wang; Niccolo’ Tesi; Silke Kern; Margda Waern; Ingmar Skoog; Argonde van Harten; Yolande A. L. Pijnenburg; Wiesje M. van der Flier; Pascual Sánchez-Juan; Eloy Rodriguez-Rodriguez; Luca Kleineidam; Oliver Peters; Anja Schneider; Fahri Küçükali; Céline Bellenguez; Benjamin Grenier-Boley; Sami Heikkinen; Itziar de Rojas; Dan Rujescu; Norbert Scherbaum; Lucrezia Hausner; Emrah Düzel; Timo Grimmer; Jens Wiltfang; Rik Vandenberghe; Sebastiaan Engelborghs; Stefanie Heilmann-Heimbach; Matthias Schmid; Thomas Tegos; Nikolaos Scarmeas; Oriol Dols-Icardo; Fermin Moreno; Jordi Pérez-Tur; María J. Bullido; Raquel Sánchez-Valle; Victoria Álvarez; Pablo García-González; Pablo Mir; Luis M. Real; Gerard Piñol-Ripoll; Jose María García-Alberca; Harro Seelaar; Inez Ramakers; Janne Papma; Marc Hulsman; Christoph Laske; Stefan Teipel; Josef Priller; Robert Perneczky; Katharina Buerger; Markus M. Nöthen; Piotr Lewczuk; Johannes Kornhuber; Harald Hampel; Ina Giegling; Oliver Goldhardt; Janine Diehl-Schmid; Victor Andrade; Michael MT. Heneka; Lutz Frölich; Jonathan Vogelgsang; Caroline Graff; Hakan Thonberg; Abbe Ullgren; Goran Papenberg; Jean-François Deleuze; Carole Dufouil; Michael Wagner; Frank Jessen; Henne Holstege; Cornelia van Duijn; Thibaud Lebouvier; Olivier Hannon; Ville Leinonen; Hilkka Soininen; Sanna-Kaisa Herukka; Vilmantas Giedraitis; Malin Löwenmark; Lena Kilander; Patricia Genius; Blanca Rodríguez; Emma S. Luckett; Arcadi Navarro; Amanda Cano; Marta Marquié; Kaj Blennow; Henrik Zetterberg; Alberto Lleo; Mercè Boada; Agustin Ruiz; Virginia Man-Yee Lee; Vivianna M. Van Deerlin; Yuetiva Deming; Sterling C. Johnson; Corinne D. Engelman; Pau Pastor; Ignacio Alvarez; Elaine R. Peskind; Amanda J. Heslegrave; Andrew J. Saykin; Kwangsik Nho; Suzanne E. Schindler; John C. Morris; David M. Holtzman; Eric McDade; Alan E. Renton; Alison Goate; Laura Ibanez; Matthias Riemenschneider; Marilyn S. Albert; Simon M. Laws; Tenielle Porter; Eleanor K. O’Brien; Leslie M. Shaw; Betty M. Tijms; Martin Ingelsson; Pieter Jelle Visser; Mikko Hiltunen; Kristel Sleegers; Craig W. Ritchie; Rebecca Sims; Michael Belloy; Jean-Charles Lambert; Natalia Vilor-Tejedor; Maria Victoria Fernández; Qingqin S. Li; Michael W. Nagle; Riccardo E. Marioni; Alfredo Ramirez; Lars Bertram; Sven J. van der Lee; Carlos Cruchaga
Author Correction: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans

作者更正：食用改良的地中海生酮饮食可逆转人类阿尔茨海默病的外周脂质特征

Communications Medicine
IF6.3
2026-04-060
OAAI
Bryan J. Neth; Kevin Huynh; Corey Giles; Tingting Wang; Natalie A. Mellett; Thy Duong; Colette Blach; Leyla Schimmel; Thomas C. Register; Kaj Blennow; Henrik Zetterberg; Richa Batra; Annalise Schweickart; Amanda Hazel Dilmore; Cameron Martino; Matthias Arnold; Jan Krumsiek; Xianlin Han; Pieter C. Dorrestein; Rob Knight; Peter J. Meikle; Suzanne Craft; Rima Kaddurah-Daouk
A Bayesian classification model for differential diagnosis of Alzheimer's disease and frontotemporal dementia using plasma biomarkers

基于血浆生物标志物的阿尔茨海默病和额颞叶痴呆鉴别诊断的贝叶斯分类模型

JOURNAL OF ALZHEIMERS DISEASE
IF3.1
2026-04-060
PRE
Tommaso Costa; Donato Liloia; Enrico Premi; Nicholas Ashton; Henrik Zettemberg; Kaj Blennow; Alessandro Padovani; Barbara Borroni
Physical activity across the life course and neural biomarkers

生命历程中的身体活动与神经生物标志物

Journal of Alzheimer’s Disease
IF0
2026-02-230
PRE
Elisa R. Torres; Eloise D. Lopez; Lydia McBurrows; Gwendlyn Kollmorgen; Margherita Carboni; Sterling C. Johnson; Henrik Zetterberg; Kaj Blennow; Barbara B. Bendlin
N-Truncated Superoxide Dismutase-1 in Cerebrospinal Fluid Is Folded and Active

脑脊液中截断型超氧化物歧化酶-1是折叠且具有活性的

Journal of Neurochemistry
IF4
2026-02-100
OAAI
Laura Leykam; Karin M. E. Forsberg; Peter M. Andersen; Thomas Brännström; Sophia Weiner; John Rönnholm; Kaj Blennow; Henrik Zetterberg; Stefan L. Marklund; Johan Gobom; Per Zetterström
Biomarker-integrated prognostic stagings for Alzheimer’s Disease

阿尔茨海默病的生物标志物综合预后分期

Nature Communications
IF15.7
2026-02-020
OAAI
Daeun Shin; Sungjoo Lee; Jun Pyo Kim; Hyemin Jang; Jihwan Yun; Min Young Chun; Jehyun Ahn; Seongmi Kim; Kyoungmin Kim; Soyeon Yoon; Hee Jin Kim; Heekyoung Kang; Sohyun Yim; Hee Kyung Park; Seonghyeon Kim; Duk L. Na; Henrik Zetterberg; Kaj Blennow; Fernando Gonzalez-Ortiz; Nicholas J. Ashton; Michael W. Weiner; Sang Won Seo; Kyunga Kim
Early functional changes and plasma GFAP in Swedish families with Autosomal Dominant Alzheimer’s disease mutations

常染色体显性遗传阿尔茨海默病突变的瑞典家庭的早期功能变化和血浆GFAP

Translational Psychiatry
IF6.2
2026-01-270
OAAI
Emma S. Luckett; Mariola Zapater-Fajari; Ove Almkvist; Charlotte Johansson; Konstantinos Chiotis; Marco Bucci; Anders Wall; Nicholas J. Ashton; Kaj Blennow; Henrik Zetterberg; Elena Rodriguez-Vieitez; Caroline Graff; Agneta Nordberg
Double cutoff strategies for plasma pTau217 to predict Tau PET positivity across multiple assay platforms: Tau-enriched and Tau-scarce cohorts for cost-effective clinical use

血浆pTau217的双重截止策略，以预测跨多个测定平台的Tau PET阳性: Tau富集和Tau稀缺的队列，以实现具有成本效益的临床使用

Alzheimer's Research & Therapy
IF7.6
2026-01-140
OAAI
Heekyoung Kang; Yuna Gu; Jungah Lee; Soyeon Yoon; Henrik Zetterberg; Kaj Blennow; Fernando Gonzalez-Ortiz; Nicholas J. Ashton; Theresa A. Day; Michael W. Weiner; Daeun Shin; Sohyun Yim; Seonghyeon Kim; Hee Kyung Park; Min Young Chun; Eun Hye Lee; Jun Pyo Kim; Hee Jin Kim; Duk L. Na; Hyemin Jang; Sang Won Seo
Inflammation‐related proteomic changes in response to amyloid and tau pathologies

对淀粉样蛋白和tau病理学反应的炎症相关蛋白质组变化

Alzheimers & Dementia
IF11.1
2026-01-080
OA
Ilaria Pola; Nicholas J. Ashton; Marco Antônio De Bastiani; Luiza Santos Machado; Guilherme Povala; Wagner S. Brum; Nesrine Rahmouni; Kübra Tan; Marisa N. Denkinger; Stijn Servaes; Joseph Therriault; Tharick A Pascoal; Kaj Blennow; Henrik Zetterberg; Eduardo R. Zimmer; Pedro Rosa‐Neto; Andrea L. Benedet
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology

一种微创的干血斑生物标志物检测方法，用于检测阿尔茨海默病的病理学

Nature Medicine
IF50
2026-01-050
OAAI
Hanna Huber; Laia Montoliu-Gaya; Wagner S. Brum; Jakub Vávra; Yara Yakoub; Haley Weninger; Luisa Sophie Braun-Wohlfahrt; Joel Simrén; Mercé Boada; Agustín Ruiz; Amanda Cano; Adelina Orellana; Sergi Valero; Laia Cañada; Natalia Tantinya; Ana Belen Nogales; Pilar Sanz-Cartagena; Anna Dittrich; Ingmar Skoog; Millie Sander-Long; Clive Ballard; Megan Richards; Mary O’Leary; Frederikke Kragh Clemmensen; Hannah H. D. Wandall; Daniele Altomare; Valentina Cantoni; Erik Stomrud; Sebastian Palmqvist; Alberto Lleo; Daniel Alcolea; Maria Carmona Iragui; Aida Sanjuan Hernandez; Bessy Benejam; Laura Videla Toro; Alpana Singh; Marisa N. Denkinger; Anja Hviid Simonsen; Silke Kern; Anne Corbett; Juan Fortea; Lee Honigberg; Barbara Borroni; Oskar Hansson; Xavier Morató; Kaj Blennow; Henrik Zetterberg; Nicholas J. Ashton
Microglia as a key player in Aβ‐related astrocyte reactivity

小胶质细胞作为Aβ相关星形胶质细胞反应性的关键参与者

Alzheimers & Dementia
IF11.1
2025-12-250
OAAI
João Pedro Ferrari‐Souza; Guilherme Povala; Nesrine Rahmouni; Bruna Bellaver; Pamela C.L. Ferreira; Douglas Teixeira Leffa; Firoza Z Lussier; Cristiano Aguzzoli; Wagner Scheeren Brum; Marco Antônio De Bastiani; Giovanna Carello‐Collar; Wyllians Vendramini Borelli; Joseph Therriault; Arthur C. Macedo; Stijn Servaes; Jenna Stevenson; Ilaria Pola; Serge Gauthier; Diogo O. Souza; Lucas Porcello Schilling; Mychael V. Lourenco; Gallen Triana‐Baltzer; Hartmuth C. Kolb; Andrea L. Benedet; Nicholas J. Ashton; Dana L Tudorascu; Henrik Zetterberg; Kaj Blennow; Tharick A Pascoal; Pedro Rosa‐Neto; Eduardo R. Zimmer

研究方向

暂未获取到该数据
H
Henrik Zetterberg
H 指数:190论文数:3,744被引数:17.9万
N
Nicholas J. Ashton
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O
Oskar Hansson
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T
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Henrik Zetterberg
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Ingmar Skoog
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P
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H
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