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B

Brijesh Kumar Singh

duke–nus medical school
H指数:43
被引数:6,223

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荣誉奖项

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ESRRA (estrogen related receptor, alpha) induces ribosomal protein RPLP1-mediated adaptive hepatic translation during prolonged starvation

ESRRA（雌激素相关受体，α）诱导核糖体蛋白RPLP1介导的适应性肝翻译以应对持续饥饿

AUTOPHAGY
IF14.3
2025-02-180
OA
Tripathi, Madhulika; Gauthier, Karine; Sandireddy, Reddemma; Zhou, Jin; Gupta, Priyanka; Sakthivel, Suganya; Jiemin, Nah; Arul, Kabilesh; Tikno, Keziah; Park, Sung-Hee; Wu, Yajun; Wang, Lijin; Bay, Boon-Huat; Ho, Lena; Giguere, Vincent; Ghosh, Sujoy; Mcdonnell, Donald P.; Yen, Paul M.; Singh, Brijesh K.
Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fasting
MOLECULAR METABOLISM
IF6.6
2024-09-010
OAAI
Tripathi, Madhulika; Gauthier, Karine; Sandireddy, Reddemma; Zhou, Jin; Guptta, Priyanka; Sakthivel, Suganya; Teo, Wei Wen; Naing, Yadanar Than; Arul, Kabilesh; Tikno, Keziah; Park, Sung-Hee; Wu, Yajun; Wang, Lijin; Bay, Boon-Huat; Sun, Lei; Giguere, Vincent; Chow, Pierce K. H.; Ghosh, Sujoy; Mcdonnell, Donald P.; Yen, Paul M.; Singh, Brijesh K.
Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation

维生素B12和叶酸通过防止syntaxin 17同型半胱氨酸化减少NASH的炎症和纤维化

JOURNAL OF HEPATOLOGY
IF33
2022-11-0157
OAAI
Tripathi, Madhulika; Singh, Brijesh Kumar; Zhou, Jin; Tikno, Keziah; Widjaja, Anissa; Sandireddy, Reddemma; Arul, Kabilesh; Ghani, Siti Aishah Binte Abdul; Bee, George Goh Boon; Wong, Kiraely Adam; Pei, Ho Jia; Shekeran, Shamini Guna; Sinha, Rohit Anthony; Singh, Manvendra K.; Cook, Stuart Alexander; Suzuki, Ayako; Lim, Teegan Reina; Cheah, Chang-Chuen; Wang, Jue; Xiao, Rui-Ping; Zhang, Xiuqing; Chow, Pierce Kah Hoe; Yen, Paul Michael
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression

亚精胺介导的翻译因子EIF5A的促尿作用可改善线粒体脂肪酸氧化并预防非酒精性脂肪性肝炎的进展

NATURE COMMUNICATIONS
IF15.7
2022-09-0342
OAAI
Zhou, Jin; Pang, Jeremy; Tripathi, Madhulika; Ho, Jia Pei; Widjaja, Anissa Anindya; Shekeran, Shamini Guna; Cook, Stuart Alexander; Suzuki, Ayako; Diehl, Anna Mae; Petretto, Enrico; Singh, Brijesh Kumar; Yen, Paul Michael
Caffeine prevents restenosis and inhibits vascular smooth muscle cell proliferation through the induction of autophagy

咖啡因通过诱导自噬防止再狭窄并抑制血管平滑肌细胞增殖

AUTOPHAGY
IF14.3
2022-01-1115
OA
Tripathi, Madhulika; Singh, Brijesh Kumar; Liehn, Elisa A.; Lim, Sheau Yng; Tikno, Keziah; Castano-Mayan, David; Rattanasopa, Chutima; Nilcham, Pakhwan; Ghani, Siti Aishah Binte Abdul; Wu, Zihao; Azhar, Syaza Hazwany; Zhou, Jin; Hernandez-Resendiz, Sauri; Crespo-Avilan, Gustavo E.; Sinha, Rohit Anthony; Farah, Benjamin Livingston; Moe, Kyaw Thu; De Silva, Deidre Anne; Angeli, Veronique; Singh, Manvendra K.; Singaraja, Roshni R.; Hausenloy, Derek J.; Yen, Paul Michael
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-06-0942
OA
Widjaja, Anissa A.; Dong, Jinrui; Adami, Eleonora; Viswanathan, Sivakumar; Ng, Benjamin; Pakkiri, Leroy S.; Chothani, Sonia P.; Singh, Brijesh K.; Lim, Wei Wen; Zhou, Jin; Shekeran, Shamini G.; Tan, Jessie; Lim, Sze Yun; Goh, Joyce; Wang, Mao; Holgate, Robert; Hearn, Arron; Felkin, Leanne E.; Yen, Paul M.; Dear, James W.; Drum, Chester L.; Schafer, Sebastian; Cook, Stuart A.

研究方向

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P
Paul M. Yen
H 指数:63论文数:269被引数:1.7万
周
周瑾
H 指数:36论文数:124被引数:4,100
M
Madhulika Tripathi
H 指数:24论文数:82被引数:2,039
R
Rohit A. Sinha
H 指数:0论文数:1被引数:41
Y
Yajun Wu
H 指数:29论文数:87被引数:3,519
B
Boon‐Huat Bay
H 指数:69论文数:378被引数:1.6万
K
Kenji Ohba
H 指数:16论文数:68被引数:1,107
A
Anissa A. Widjaja
H 指数:26论文数:68被引数:3,870
S
Stuart A. Cook
H 指数:95论文数:467被引数:3.4万
S
Shamini G. Shekeran
H 指数:14论文数:23被引数:1,300